1,148 research outputs found
CO ro-vibrational lines in HD100546: A search for disc asymmetries and the role of fluorescence
We have studied the emission of CO ro-vibrational lines in the disc around
the Herbig Be star HD100546 with the final goal of using these lines as a
diagnostic to understand inner disc structure in the context of planet
formation. High-resolution IR spectra of CO ro-vibrational emission at eight
different position angles were taken with CRIRES at the VLT. From these spectra
flux tables, CO ro-vibrational line profiles, and population diagrams were
produced. We have investigated variations in the line profile shapes and line
strengths as a function of slit position angle. We used the thermochemical disc
modelling code ProDiMo based on the chemistry, radiation field, and temperature
structure of a previously published model for HD100546. Comparing observations
and the model, we investigated the possibility of disc asymmetries, the
excitation mechanism (UV fluorescence), the geometry, and physical conditions
of the inner disc. The observed CO ro-vibrational lines are largely emitted
from the inner rim of the outer disc at 10-13 AU. The line shapes are similar
for all v levels and line fluxes from all vibrational levels vary only within
one order of magnitude. All line profile asymmetries and variations can be
explained with a symmetric disc model to which a slit correction and pointing
offset is applied. Because the angular size of the CO emitting region (10-13
AU) and the slit width are comparable the line profiles are very sensitive to
the placing of the slit. The model reproduces the line shapes and the fluxes of
the v=1-0 lines as well as the spatial extent of the CO ro-vibrational
emission. It does not reproduce the observed band ratios of 0.5-0.2 with higher
vibrational bands. We find that lower gas volume densities at the surface of
the inner rim of the outer disc can make the fluorescence pumping more effcient
and reproduce the observed band ratios.Comment: 20 pages, 21 figure
Models and metaphors: complexity theory and through-life management in the built environment
Complexity thinking may have both modelling and metaphorical applications in the through-life management of the built environment. These two distinct approaches are examined and compared. In the first instance, some of the sources of complexity in the design, construction and maintenance of the built environment are identified. The metaphorical use of complexity in management thinking and its application in the built environment are briefly examined. This is followed by an exploration of modelling techniques relevant to built environment concerns. Non-linear and complex mathematical techniques such as fuzzy logic, cellular automata and attractors, may be applicable to their analysis. Existing software tools are identified and examples of successful built environment applications of complexity modelling are given. Some issues that arise include the definition of phenomena in a mathematically usable way, the functionality of available software and the possibility of going beyond representational modelling. Further questions arising from the application of complexity thinking are discussed, including the possibilities for confusion that arise from the use of metaphor. The metaphor of a 'commentary machine' is suggested as a possible way forward and it is suggested that an appropriate linguistic analysis can in certain situations reduce perceived complexity
A phylogenomic analysis of the role and timing of molecular adaptation in the aquatic transition of cetartiodactyl mammals
This work was funded by the European Research Council (ERC 1076 Starting grant no. 310482) awarded to S.J.R. and a Newton International Fellowship awarded to M.R.M
The inter- and intrarater reliability and agreement for field-based assessment of scapular control, shoulder range of motion, and shoulder isometric strength in elite adolescent athletes
Objectives
To investigate the intra- and interrater reliability and agreement for field-based assessment of scapular control, shoulder range of motion (ROM), and shoulder isometric strength in elite youth athletes.
Design
Test-retest reliability and agreement study.
Setting
Eight blinded raters (two for each assessment) assessed players on field during two testing sessions separated by one week.
Participants
162 elite youth handball players with or without a history of previous shoulder pain within the preceding six months.
Main outcome measures
Kappa (κ) and prevalence-adjusted bias-adjusted kappa (PABAK) coefficients for scapular control reliability, and 95% limits of agreement (LOA) for ROM and strength agreement.
Results
Scapular control demonstrated substantial to almost perfect reliability (κ 0.67 to 0.84, PABAK from 0.68 to 0.88). Mean strength values ranged from 0.9 N/kg to 1.6 N/kg, and LOAs ranged from −0.7 N/kg to 0.8 N/kg. Rotational strength revealed additionally systematic bias between and within rater. No or acceptable systematic bias were evident for ROM and abduction strength measures. Mean values and LOAs for ROM ranged between 39.9° to 52.3°, and from −12.6° to 9.9°, respectively.
Conclusions
Scapular control and ROM can be assessed on the field with acceptable reliability. The threshold for reliable measurements of isometric strength using handheld-dynamometers is high
Organocatalysis with Endogenous Compounds: Towards Novel Non-enzymatic Reactions
The aldol reaction of the endogeneous compounds acetone and methylglyoxal has been studied using organocatalysis in relation to biologically relevant non-enzymatic reactions. Under preparative conditions, 3-hydroxy-2,5-hexadione, known as Henze’s ketol, is formed in high yield and with enantioselectivities up to 88% ee. Furthermore, Henze’s ketol is also formed under simulated physiological conditions at micromolar scale, indicating that this reaction might take place in living organisms
Determining ‘Age at Death’ for Forensic Purposes using Human Bone by a Laboratory-based Analytical Method
Determination of age-at-death (AAD) is an important and frequent requirement in contemporary forensic science and in the reconstruction of past populations and societies from their remains. Its estimation is relatively straightforward and accurate (±3 years) for immature skeletons by using morphological features and reference tables within the context of forensic anthropology. However, after skeletal maturity (>35 yrs) estimates become inaccurate, particularly in the legal context. In line with the general migration of all the forensic sciences from reliance upon empirical criteria to those which are more evidence-based, AAD determination should rely more-and-more upon more quantitative methods. We explore here whether well-known changes in the biomechanical properties of bone and the properties of bone matrix, which have been seen to change with age even after skeletal maturity in a traceable manner, can be used to provide a reliable estimate of AAD. This method charts a combination of physical characteristics some of which are measured at a macroscopic level (wet & dry apparent density, porosity, organic/mineral/water fractions, collagen thermal degradation properties, ash content) and others at the microscopic level (Ca/P ratios, osteonal and matrix microhardness, image analysis of sections). This method produced successful age estimates on a cohort of 12 donors of age 53–85 yr (7 male, 5 female), where the age of the individual could be approximated within less than ±1 yr. This represents a vastly improved level of accuracy than currently extant age estimation techniques. It also presents: (1) a greater level of reliability and objectivity as the results are not dependent on the experience and expertise of the observer, as is so often the case in forensic skeletal age estimation methods; (2) it is purely laboratory-based analytical technique which can be carried out by someone with technical skills and not the specialised forensic anthropology experience; (3) it can be applied worldwide following stringent laboratory protocols. As such, this technique contributes significantly to improving age estimation and therefore identification methods for forensic and other purposes
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