280 research outputs found
Monitoring neurotoxins in industry: development of a neurobehavioral test battery
Huguet Françoise. 104 - Elémens (Les) ou premières instructions de la jeunesse. In: , . Les Livres pour l'Enfance et la Jeunesse de Gutenberg à Guizot. Les collections de la Bibliothèque de l'Institut National de Recherche Pédagogique. Paris : Institut national de recherche pédagogique, 1997. p. 57. (Bibliothèque de l'Histoire de l'Education, 16
Coincident extremely large sporadic sodium and sporadic E layers observed in the lower thermosphere over Colorado and Utah
International audienceOn the night of 2 June 2002, the sodium lidar in Fort Collins, CO (40.6 N, 105 W) measured an extremely strong sporadic sodium layer lasting from 03:30 to 05:00 UT with several weaker layers later in the night at 06:00 and 09:00 UT. There is a double layer structure with peaks at 101 and 104 km. The peak sodium density was 21 000 atoms/cm3 with a column abundance of up to twice that of the normal sodium layer. The peak density was 500 times greater than the typical density at that altitude. The sporadic layer abundance and strength factor were higher than any reported in the literature. The two lidar beams, separated by 70 km at this altitude, both measured 0.6 h periodicities in the abundance, but out of phase with each other by 0.3 h. There is also evidence for strong wave activity in the lidar temperatures and winds. The NOAA ionosonde in Boulder, CO (40.0 N, 105 W) measured a critical frequency (foEs) of 14.3 MHz at 03:00 UT on this night, the highest value anytime during 2002. The high values of total ion density inferred means that Na+ fraction must have been only a few percent to explain the neutral Na layer abundances. The Bear Lake, Utah (41.9 N, 111.4 W) dynasonde also measured intense Es between 02:00 and 05:00 UT and again from 06:00 to 08:00 UT about 700 km west of the lidar, with most of the ionograms during these intervals measuring Es up to 12 MHz, the limit of the ionosonde sweep. Other ionosondes around North America on the NGDC database measured normal foEs values that night, so it was a localized event within North America. The peak of Es activity observed in Europe during the summer of 2002 occurred on 4 June. The observations are consistent with the current theories where a combination of wind shears and long period waves form and push downward a concentrated layer of ions, which then chemically react and form a narrow layer of sodium atoms
Occupational lead neurotoxicity: Improvement in behavioural effects after reduction of exposure.
To evaluate critical exposure levels and the reversibility of lead neurotoxicity a group of lead exposed foundry workers and an unexposed reference population were followed up for three years. During this period, tests designed to monitor neurobehavioural function and lead dose were administered. Evaluations of 160 workers during the first year showed dose dependent decrements in mood, visual/motor performance, memory, and verbal concept formation. Subsequently, an improvement in the hygienic conditions at the plant resulted in striking reductions in blood lead concentrations over the following two years. Attendant improvement in indices of tension (20% reduction), anger (18%), depression (26%), fatigue (27%), and confusion (13%) was observed. Performance on neurobehavioural testing generally correlated best with integrated dose estimates derived from blood lead concentrations measured periodically over the study period; zinc protoporphyrin levels were less well correlated with function. This investigation confirms the importance of compliance with workplace standards designed to lower exposures to ensure that individual blood lead concentrations remain below 50 micrograms/dl
ASTRA: ASTrometry and phase-Referencing Astronomy on the Keck interferometer
ASTRA (ASTrometric and phase-Referencing Astronomy) is an upgrade to the
existing Keck Interferometer which aims at providing new self-phase referencing
(high spectral resolution observation of YSOs), dual-field phase referencing
(sensitive AGN observations), and astrometric (known exoplanetary systems
characterization and galactic center general relativity in strong field regime)
capabilities. With the first high spectral resolution mode now offered to the
community, this contribution focuses on the progress of the dual field and
astrometric modes.Comment: 10 pages, 6 figures, 2 tables, SPIE 201
Keck Interferometer Nuller Data Reduction and On-Sky Performance
We describe the Keck Interferometer nuller theory of operation, data reduction, and on-sky performance, particularly as it applies to the nuller exozodiacal dust key science program that was carried out between 2008 February and 2009 January. We review the nuller implementation, including the detailed phasor processing involved in implementing the null-peak mode used for science data and the sequencing used for science observing. We then describe the Level 1 reduction to convert the instrument telemetry streams to raw null leakages, and the Level 2 reduction to provide calibrated null leakages. The Level 1 reduction uses conservative, primarily linear processing, implemented consistently for science and calibrator stars. The Level 2 processing is more flexible, and uses diameters for the calibrator stars measured contemporaneously with the interferometer’s K-band cophasing system in order to provide the requisite accuracy. Using the key science data set of 462 total scans, we assess the instrument performance for sensitivity and systematic error. At 2.0 Jy we achieve a photometrically-limited null leakage uncertainty of 0.25% rms per 10 minutes of integration time in our broadband channel. From analysis of the Level 2 reductions, we estimate a systematic noise floor for bright stars of ~0.2% rms null leakage uncertainty per observing cluster in the broadband channel. A similar analysis is performed for the narrowband channels. We also provide additional information needed for science reduction, including details on the instrument beam pattern and the basic astrophysical response of the system, and references to the data reduction and modeling tools
Regular breakfast consumption and type 2 diabetes risk markers in 9- to 10-year-old children in the child heart and health study in England (CHASE): a cross-sectional analysis.
BACKGROUND: Regular breakfast consumption may protect against type 2 diabetes risk in adults but little is known about its influence on type 2 diabetes risk markers in children. We investigated the associations between breakfast consumption (frequency and content) and risk markers for type 2 diabetes (particularly insulin resistance and glycaemia) and cardiovascular disease in children.
METHODS AND FINDINGS: We conducted a cross-sectional study of 4,116 UK primary school children aged 9-10 years. Participants provided information on breakfast frequency, had measurements of body composition, and gave fasting blood samples for measurements of blood lipids, insulin, glucose, and glycated haemoglobin (HbA1c). A subgroup of 2,004 children also completed a 24-hour dietary recall. Among 4,116 children studied, 3,056 (74%) ate breakfast daily, 450 (11%) most days, 372 (9%) some days, and 238 (6%) not usually. Graded associations between breakfast frequency and risk markers were observed; children who reported not usually having breakfast had higher fasting insulin (percent difference 26.4%, 95% CI 16.6%-37.0%), insulin resistance (percent difference 26.7%, 95% CI 17.0%-37.2%), HbA1c (percent difference 1.2%, 95% CI 0.4%-2.0%), glucose (percent difference 1.0%, 95% CI 0.0%-2.0%), and urate (percent difference 6%, 95% CI 3%-10%) than those who reported having breakfast daily; these differences were little affected by adjustment for adiposity, socioeconomic status, and physical activity levels. When the higher levels of triglyceride, systolic blood pressure, and C-reactive protein for those who usually did not eat breakfast relative to those who ate breakfast daily were adjusted for adiposity, the differences were no longer significant. Children eating a high fibre cereal breakfast had lower insulin resistance than those eating other breakfast types (p for heterogeneity <0.01). Differences in nutrient intakes between breakfast frequency groups did not account for the differences in type 2 diabetes markers.
CONCLUSIONS: Children who ate breakfast daily, particularly a high fibre cereal breakfast, had a more favourable type 2 diabetes risk profile. Trials are needed to quantify the protective effect of breakfast on emerging type 2 diabetes risk. Please see later in the article for the Editors' Summary
Asteroseismology of the Beta Cephei star 12 (DD) Lacertae: photometric observations, pulsational frequency analysis and mode identification
We report a multisite photometric campaign for the Beta Cephei star 12
Lacertae. 750 hours of high-quality differential photoelectric Stromgren,
Johnson and Geneva time-series photometry were obtained with 9 telescopes
during 190 nights. Our frequency analysis results in the detection of 23
sinusoidal signals in the light curves. Eleven of those correspond to
independent pulsation modes, and the remainder are combination frequencies. We
find some slow aperiodic variability such as that seemingly present in several
Beta Cephei stars. We perform mode identification from our colour photometry,
derive the spherical degree l for the five strongest modes unambiguously and
provide constraints on l for the weaker modes. We find a mixture of modes of 0
<= l <= 4. In particular, we prove that the previously suspected rotationally
split triplet within the modes of 12 Lac consists of modes of different l;
their equal frequency splitting must thus be accidental.
One of the periodic signals we detected in the light curves is argued to be a
linearly stable mode excited to visible amplitude by nonlinear mode coupling
via a 2:1 resonance. We also find a low-frequency signal in the light
variations whose physical nature is unclear; it could be a parent or daughter
mode resonantly coupled. The remaining combination frequencies are consistent
with simple light-curve distortions.
The range of excited pulsation frequencies of 12 Lac may be sufficiently
large that it cannot be reproduced by standard models. We suspect that the star
has a larger metal abundance in the pulsational driving zone, a hypothesis also
capable of explaining the presence of Beta Cephei stars in the LMC.Comment: 12 pages, 7 figures, MNRAS, in pres
Preliminary seismological and geological studies of the San Fernando, California, earthquake of February 9 1971
The San Fernando earthquake was the largest earthquake to occur in the metropolitan Los
Angeles area in more than 50 years. It has tentatively been assigned a magnitude, M_L of 6.6, a focal
depth of 13.0 km, and an epicentral location about 12 km east of Newhall, California, at 34°24.0'N,
118°23.7'W (Figure 1), but these figures undoubtedly will be modified as further data become available.
Although the focal depth is not as well defined as the epicenter, it is consistent with other
observations suggesting thrusting on a fault plane dipping north about 45 ° and breaking the surface
in the Sylmar-San Fernando area (Figure 1). It should be emphasized that the hypocenter of
the main shock represents only the point of initial rupture. Breaking, presumably, then propagated
southward and upward from this point, so that the main geological and engineering effects
were observed farther south where the fault was shallower and the displacement greater. The location
of the main shock is based on readings from permanent stations of the Caltech network, as
well as the U. S. Geological Survey station at Point Mugu (SBLG) and the California Department
of Water Resources stations at Pyramid (PYR) and Cedar Springs (CSP). Portable Caltech seismographs
were installed in the epicentral area as early as 3 hr following the main shock, and,
within a few days, there were at least 30 portable units in the region operated by various groups
and agencies
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