11,022 research outputs found
The Specialized Role of the S1 Transmembrane Segment in the Gating of the Hv1 Proton Channel
Relative Humidity and Activity Patterns of \u3cem\u3eIxodes scapularis\u3c/em\u3e (Acari: Ixodidae)
Laboratory studies have shown clear relationships between relative humidity (RH) and the activity and survival of Ixodes scapularis Say (blacklegged tick). However, field studies have produced conflicting results. We examined this relationship using weekly tick count totals and hourly RH observations at three field sites, stratified by latitude, within the state of Rhode Island. Records of nymphal tick abundance were compared with several RH-related variables (e.g., RH at time of sampling and mean weekly daytime RH). In total, 825 nymphs were sampled in 2009, a year of greater precipitation, with a weighted average leaf litter RH recorded at time of sampling of 85.22%. Alternatively, 649 nymphs were collected in 2010, a year of relatively low precipitation, and a weighted average RH recorded at time of sampling was 75.51%. Negative binomial regression analysis of tick count totals identified cumulative hours P = 0.0037; 2010: P \u3c 0.0001). Mean weekly daytime RH did not significantly predict tick activity in either year. However, mean weekly daytime RH recorded with 1-wk lag before sample date was a significant variable (P = 0.0016) in 2010. These results suggest a lag effect between moisture availability and patterns of tick activity and abundance. Differences in the relative importance of each RH variable between years may have been due to abnormally wet summer conditions in 2009
Resolution of the clinical features of tyrosinemia following orthotopic liver transplantation for hepatoma
The clinical history before transplantation and subsequent clinical and biochemical course of 3 children and one adult with hereditary tyrosinemia treated by orthotopic hepatic transplantation is described. All four patients are now free of their previous dietary restrictions and appear to be cured of both their metabolic disease and their hepatic neoplasm. © 1986 Elsevier Science Publishers B.V. All rights reserved
Proton Stability in Six Dimensions
We show that Lorentz and gauge invariance explain the long proton lifetime
within the standard model in six dimensions. The baryon-number violating
operators have mass dimension 15 or higher. Upon TeV-scale compactification of
the two universal extra dimensions on a square orbifold, a discrete
subgroup of the 6-dimensional Lorentz group continues to forbid dangerous
operators.Comment: PRL accepted versio
Post-translational derepression of invertase activity in source leaves via down-regulation of invertase inhibitor expression is part of the plant defense response
There is increasing evidence that pathogens do not only elicit direct defense responses, but also cause pronounced changes in primary carbohydrate metabolism. Cell-wall-bound invertases belong to the key regulators of carbohydrate partitioning and source-sink relations. Whereas studies have focused so far only on the transcriptional induction of invertase genes in response to pathogen infection, the role of post-translational regulation of invertase activity has been neglected and was the focus of the present study. Expression analyses revealed that the high mRNA level of one out of three proteinaceous invertase inhibitors in source leaves of Arabidopsis thaliana is strongly repressed upon infection by a virulent strain of Pseudomonas syringae pv. tomato DC3000. This repression is paralleled by a decrease in invertase inhibitor activity. The physiological role of this regulatory mechanism is revealed by the finding that in situ invertase activity was detectable only upon infection by P. syringae. In contrast, a high invertase activity could be measured in vitro in crude and cell wall extracts prepared from both infected and non-infected leaves. The discrepancy between the in situ and in vitro invertase activity of control leaves and the high in situ invertase activity in infected leaves can be explained by the pathogen-dependent repression of invertase inhibitor expression and a concomitant reduction in invertase inhibitor activity. The functional importance of the release of invertase from post-translational inhibition for the defense response was substantiated by the application of the competitive chemical invertase inhibitor acarbose. Post-translational inhibition of extracellular invertase activity by infiltration of acarbose in leaves was shown to increase the susceptibility to P. syringae. The impact of invertase inhibition on spatial and temporal dynamics of the repression of photosynthesis and promotion of bacterial growth during pathogen infection supports a role for extracellular invertase in plant defense. The acarbose-mediated increase in susceptibility was also detectable in sid2 and cpr6 mutants and resulted in slightly elevated levels of salicylic acid, demonstrating that the effect is independent of the salicylic acid-regulated defense pathway. These findings provide an explanation for high extractable invertase activity found in source leaves that is kept inhibited in situ by post-translational interaction between invertase and the invertase inhibitor proteins. Upon pathogen infection, the invertase activity is released by repression of invertase inhibitor expression, thus linking the local induction of sink strength to the plant defense response
Gauge Field Formulation of Adiabatic Spin Torques
Previous calculation of spin torques for small-amplitude magnetization
dynamics around a uniformly magnetized state [J. Phys. Soc. Jpn. {\bf 75}
(2006) 113706] is extended here to the case of finite-amplitude dynamics. This
is achieved by introducing an `` adiabatic'' spin frame for conduction
electrons, and the associated SU(2) gauge field. In particular, the Gilbert
damping is shown to arise from the time variation of the spin-relaxation source
terms in this new frame, giving a new physical picture of the damping. The
present method will allow a `` first-principle'' derivation of spin torques
without any assumptions such as rotational symmetry in spin space.Comment: 4 pages, 3 figure
Vesicles in Apollo 15 Green Glasses: The Nature of Ancient Lunar Gases
Detailed studies of Apollo 15 green glass and related beads have shown they were formed in gas-rich fire fountains.. As the magmatic fluid became super-saturated in volatile gas, bubbles or vesicles formed within the magma. These exsolved gases became trapped within vesicles as the glasses were ejected from the fire-fountain and subsequently quenched. One of the keys to understanding formation processes on the ancient moon includes determining the composition of volatile species and elements, including metals, dissolved in magmatic gases. Here we report the nature of mineral phases spatially associated with vesicles in a green glass bead from Apollo sample 15411,42. The phases reflect the composition of the cooling/degassing magmatic vapors and fluids present at the time of bead formation approx, 3 Ga ag
Towards W b bbar + j at NLO with an automatized approach to one-loop computations
We present results for the O(alpha_s) virtual corrections to q g -> W b bbar
q' obtained with a new automatized approach to the evaluation of one-loop
amplitudes in terms of Feynman diagrams. Together with the O(alpha_s)
corrections to q q' -> W b bbar g, which can be obtained from our results by
crossing symmetry, this represents the bulk of the next-to-leading order
virtual QCD corrections to W b bbar + j and W b + j hadronic production,
calculated in a fixed-flavor scheme with four light flavors. Furthermore, these
corrections represent a well defined and independent subset of the 1-loop
amplitudes needed for the NNLO calculation of W b bbar. Our approach was tested
against several existing results for NLO amplitudes including selected
O(alpha_s) one-loop corrections to W + 3 j hadronic production. We discuss the
efficiency of our method both with respect to evaluation time and numerical
stability.Comment: 14 pages, 3 figure
Brightness, distribution, and evolution of sunspot umbral dots
We present a 106-minute TiO (705.7nm) time series of high spatial and
temporal resolution that contains thousands of umbral dots (UDs) in a mature
sunspot in the active region NOAA 10667 at =0.95. The data were acquired
with the 1-m Swedish Solar Telescope on La Palma. With the help of a multilevel
tracking (MLT) algorithm the sizes, brightnesses, and trajectories of 12836
umbral dots were found and analyzed. The MLT allows UDs with very low contrast
to be reliably identified. Inside the umbra we determine a UD filling factor of
11%. The histogram of UD lifetimes is monotonic, i.e. a UD does not have a
typical lifetime. Three quarters of the UDs lived for less than 150s and showed
no or little motion. The histogram of the UD diameters exhibits a maximum at
225km, i.e. most of the UDs are spatially resolved. UDs display a typical
horizontal velocity of 420m/s and a typical peak intensity of 51% of the mean
intensity of the quiet photosphere, making them on average 20% brighter than
the local umbral background. Almost all mobile UDs (large birth-death distance)
were born close to the umbra-penumbra boundary, move towards the umbral center,
and are brighter than average. Notably bright and mobile UDs were also observed
along a prominent UD chain, both ends of which are located at the
umbra-penumbra boundary. Their motion started primarily at either of the ends
of the chain, continued along the chain, and ended near the chain's center. We
observed the splitting and merging of UDs and the temporal succession of both.
For the first time the evolution of brightness, size, and horizontal speed of a
typical UD could be determined in a statistically significant way. Considerable
differences between the evolution of central and peripheral UDs are found,
which point to a difference in origin
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