The spectral difference between solar flare HXR coronal and footpoint sources due to wave-particle interactions

Investigate the spatial and spectral evolution of hard X-ray (HXR) emission from flare accelerated electron beams subject to collisional transport and wave-particle interactions in the solar atmosphere. We numerically follow the propagation of a power-law of accelerated electrons in 1D space and time with the response of the background plasma in the form of Langmuir waves using the quasilinear approximation.}{We find that the addition of wave-particle interactions to collisional transport for a transient initially injected electron beam flattens the spectrum of the footpoint source. The coronal source is unchanged and so the difference in the spectral indices between the coronal and footpoint sources is \Delta \gamma > 2, which is larger than expected from purely collisional transport. A steady-state beam shows little difference between the two cases, as has been previously found, as a transiently injected electron beam is required to produce significant wave growth, especially at higher velocities. With this transiently injected beam the wave-particle interactions dominate in the corona whereas the collisional losses dominate in the chromosphere. The shape of the spectrum is different with increasing electron beam density in the wave-particle interaction case whereas with purely collisional transport only the normalisation is changed. We also find that the starting height of the source electron beam above the photosphere affects the spectral index of the footpoint when Langmuir wave growth is included. This may account for the differing spectral indices found between double footpoints if asymmetrical injection has occurred in the flaring loop.Comment: 10 pages, 10 FIgures, accepted for publication in A&

Can gas in young debris disks be constrained by their radial brightness profiles?

Disks around young stars are known to evolve from optically thick, gas-dominated protoplanetary disks to optically thin, almost gas-free debris disks. It is thought that the primordial gas is largely removed at ages of ~10 Myr, but it is difficult to discern the true gas densities from gas observations. This suggests using observations of dust: it has been argued that gas, if present with higher densities, would lead to flatter radial profiles of the dust density and surface brightness than those actually observed. However, here we show that these profiles are surprisingly insensitive to variation of the parameters of a central star, location of the dust-producing planetesimal belt, dustiness of the disk and - most importantly - the parameters of the ambient gas. This result holds for a wide range of gas densities (three orders of magnitude), for different radial distributions of the gas temperature, and different gas compositions. The brightness profile slopes of -3...-4 we find are the same that were theoretically found for gas-free debris disks, and they are the same as actually retrieved from observations of many debris disks. Our specific results for three young (10-30 Myr old), spatially resolved, edge-on debris disks (beta Pic, HD 32297, and AU Mic) show that the observed radial profiles of the surface brightness do not pose any stringent constraints on the gas component of the disk. We cannot exclude that outer parts of the systems may have retained substantial amounts of primordial gas which is not evident in the gas observations (e.g. as much as 50 Earth masses for beta Pic). However, the possibility that gas, most likely secondary, is only present in little to moderate amounts, as deduced from gas detections (e.g. ~0.05 Earth masses in the beta Pic disk), remains open, too.Comment: Accepted for publication in Astronomy and Astrophysic

Variable turbulent convection as the cause of the Blazhko effect - testing the Stothers model

The amplitude and phase modulation observed in a significant fraction of the RR Lyrae variables - the Blazhko effect - represents a long-standing enigma in stellar pulsation theory. No satisfactory explanation for the Blazhko effect has been proposed so far. In this paper we focus on the Stothers (2006) idea, in which modulation is caused by changes in the structure of the outer convective zone, caused by a quasi-periodically changing magnetic field. However, up to this date no quantitative estimates were made to investigate whether such a mechanism can be operational and whether it is capable of reproducing the light variation we observe in Blazhko variables. We address the latter problem. We use a simplified model, in which the variation of turbulent convection is introduced into the non-linear hydrodynamic models in an ad hoc way, neglecting interaction with the magnetic field. We study the light curve variation through the modulation cycle and properties of the resulting frequency spectra. Our results are compared with Kepler observations of RR Lyr. We find that reproducing the light curve variation, as is observed in RR Lyr, requires a huge modulation of the mixing length, of the order of +/-50 per cent, on a relatively short time-scale of less than 40 days. Even then, we are not able to reproduce neither all the observed relations between modulation components present in the frequency spectrum, nor the relations between Fourier parameters describing the shape of the instantaneous light curves.Comment: 17 pages, 13 figures, accepted for publication in MNRAS; for associated animation, see http://homepage.univie.ac.at/radek.smolec/publications/KASC11a

Estimated incidence of previously undetected atrial fibrillation on a 14-day continuous electrocardiographic monitor and associated risk of stroke

Aims There is uncertainty about whether and how to perform screening for atrial fibrillation (AF). To estimate the incidence of previously undetected AF that would be captured using a continuous 14-day ECG monitor and the associated risk of stroke. Methods and results We analysed data from a cohort of patients >65 years old with hypertension and a pacemaker, but without known AF. For each participant, we simulated 1000 ECG monitors by randomly selecting 14-day windows in the 6 months following enrolment and calculated the average AF burden (total time in AF). We used Cox proportional hazards models adjusted for CHA(2)DS(2)-VASc score to estimate the risk of subsequent ischaemic stroke or systemic embolism (SSE) associated with burdens of AF > and 6 min was 3.10% (95% CI 2.53-3.72). This was consistent across strata of age and CHA(2)DS(2)-VASc scores. Over a mean follow-up of 2.4 years, the rate of SSE among patients with 6 min of AF. Conclusions Approximately 3% of individuals aged >65 years with hypertension may have more than 6 min of AF detected by a 14-day ECG monitor. This is associated with a stroke risk of over 2% per year. Whether oral anticoagulation will reduce stroke in these patients is unknown

Planetary population synthesis

In stellar astrophysics, the technique of population synthesis has been successfully used for several decades. For planets, it is in contrast still a young method which only became important in recent years because of the rapid increase of the number of known extrasolar planets, and the associated growth of statistical observational constraints. With planetary population synthesis, the theory of planet formation and evolution can be put to the test against these constraints. In this review of planetary population synthesis, we first briefly list key observational constraints. Then, the work flow in the method and its two main components are presented, namely global end-to-end models that predict planetary system properties directly from protoplanetary disk properties and probability distributions for these initial conditions. An overview of various population synthesis models in the literature is given. The sub-models for the physical processes considered in global models are described: the evolution of the protoplanetary disk, the planets' accretion of solids and gas, orbital migration, and N-body interactions among concurrently growing protoplanets. Next, typical population synthesis results are illustrated in the form of new syntheses obtained with the latest generation of the Bern model. Planetary formation tracks, the distribution of planets in the mass-distance and radius-distance plane, the planetary mass function, and the distributions of planetary radii, semimajor axes, and luminosities are shown, linked to underlying physical processes, and compared with their observational counterparts. We finish by highlighting the most important predictions made by population synthesis models and discuss the lessons learned from these predictions - both those later observationally confirmed and those rejected.Comment: 47 pages, 12 figures. Invited review accepted for publication in the 'Handbook of Exoplanets', planet formation section, section editor: Ralph Pudritz, Springer reference works, Juan Antonio Belmonte and Hans Deeg, Ed

Exotic ρ±ρ0\rho^\pm\rho^0 state photoproduction

It is shown that the list of unusual mesons planned for a careful study in photoproduction can be extended by the exotic states $X^\pm(1600)$ with $I^G(J ^{PC})=2^+(2^{++})$ which should be looked for in the $\rho^\pm\rho^0$ decay channels in the reactions $\gamma N\to\rho^\pm\rho^0N$ and $\gamma N\to\rho^\pm \rho^0\Delta$. The full classification of the $\rho^\pm\rho^0$ states by their quantum numbers is presented. A simple model for the spin structure of the $\gamma p\to f_2(1270)p$, $\gamma p\to a^0_2(1320)p$, and $\gamma N\to X^\pm (N, \Delta)$ reaction amplitudes is formulated and the tentative estimates of the corresponding cross sections at the incident photon energy $E_\gamma\approx 6$ GeV are obtained: $\sigma(\gamma p\to f_2(1270)p)\approx0.12$ $\mu$b, $\sigma(\gamma p\to a^0_2(1320)p)\approx0.25$ $\mu$b, $\sigma(\gamma N\to X^\pm N\to\rho^\pm\rho^0N)\approx0.018$ $\mu$b, and $\sigma(\gamma p\to X^-\Delta^{++ }\to\rho^-\rho^0\Delta^{++})\approx0.031$ $\mu$b. The problem of the $X^\pm$ signal extraction from the natural background due to the other $\pi^\pm\pi^0 \pi^+\pi^-$ production channels is discussed. In particular the estimates are presented for the $\gamma p\to h_1(1170)\pi^+n$, $\gamma p\to\rho'^{+}n\to \pi^+\pi^0\pi^+\pi^-n$, and $\gamma p\to\omega\rho^0p$ reaction cross sections. Our main conclusion is that the search for the exotic $X^\pm(2^+(2^{++}))$ states is quite feasible at JEFLAB facility. The expected yield of the $\gamma N\to X^\pm N\to\rho^\pm\rho^0N$ events in a 30-day run at the 100% detection efficiency approximates $2.8\times10^6$ events.Comment: 19 pages, revtex, 1 figure in postscipt, some comments and references added, a few minor typos corrected, to be published in Phys. Rev.

Acute kidney disease and renal recovery : consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup

Consensus definitions have been reached for both acute kidney injury (AKI) and chronic kidney disease (CKD) and these definitions are now routinely used in research and clinical practice. The KDIGO guideline defines AKI as an abrupt decrease in kidney function occurring over 7 days or less, whereas CKD is defined by the persistence of kidney disease for a period of > 90 days. AKI and CKD are increasingly recognized as related entities and in some instances probably represent a continuum of the disease process. For patients in whom pathophysiologic processes are ongoing, the term acute kidney disease (AKD) has been proposed to define the course of disease after AKI; however, definitions of AKD and strategies for the management of patients with AKD are not currently available. In this consensus statement, the Acute Disease Quality Initiative (ADQI) proposes definitions, staging criteria for AKD, and strategies for the management of affected patients. We also make recommendations for areas of future research, which aim to improve understanding of the underlying processes and improve outcomes for patients with AKD

The Evolution of Compact Binary Star Systems

We review the formation and evolution of compact binary stars consisting of white dwarfs (WDs), neutron stars (NSs), and black holes (BHs). Binary NSs and BHs are thought to be the primary astrophysical sources of gravitational waves (GWs) within the frequency band of ground-based detectors, while compact binaries of WDs are important sources of GWs at lower frequencies to be covered by space interferometers (LISA). Major uncertainties in the current understanding of properties of NSs and BHs most relevant to the GW studies are discussed, including the treatment of the natal kicks which compact stellar remnants acquire during the core collapse of massive stars and the common envelope phase of binary evolution. We discuss the coalescence rates of binary NSs and BHs and prospects for their detections, the formation and evolution of binary WDs and their observational manifestations. Special attention is given to AM CVn-stars -- compact binaries in which the Roche lobe is filled by another WD or a low-mass partially degenerate helium-star, as these stars are thought to be the best LISA verification binary GW sources.Comment: 105 pages, 18 figure

Genetic and Cellular Characterization of Caenorhabditis elegans Mutants Abnormal in the Regulation of Many Phase II Enzymes

Background: The phase II detoxification enzymes execute a major protective role against xenobiotics as well as endogenous toxicants. To understand how xenobiotics regulate phase II enzyme expression, acrylamide was selected as a model xenobiotic chemical, as it induces a large number and a variety of phase II enzymes, including numerous glutathione S-transferases (GSTs) in Caenorhabditis elegans. Methodology/Principal Findings: To begin dissecting genetically xenobiotics response pathways (xrep), 24 independent mutants of C. elegans that exhibited abnormal GST expression or regulation against acrylamide were isolated by screening about 3.5610 5 genomes of gst::gfp transgenic strains mutagenized with ethyl methanesulfonate (EMS). Complementation testing assigned the mutants to four different genes, named xrep-1,-2,-3, and-4. One of the genes, xrep-1, encodes WDR-23, a nematode homologue of WD repeat-containing protein WDR23. Loss-of-function mutations in xrep-1 mutants resulted in constitutive expression of many GSTs and other phase II enzymes in the absence of acrylamide, and the wild-type xrep-1 allele carried on a DNA construct successfully cured the mutant phenotype of the constitutive enzyme expression. Conclusions/Significance: Genetic and cellular characterization of xrep-1 mutants suggest that a large number of GSTs and other phase II enzymes induced by acrylamide are under negative regulation by XREP-1 (WDR-23), which is likely to be a functional equivalent of mammalian Keap1 and a regulator of SKN-1, a C. elegans analogue of cap-n-collar Nrf2 (nuclea