Propagation of short-period gravity waves at high-latitudes during the MaCWAVE winter campaign

As part of the MaCWAVE (Mountain and Convective Waves Ascending Vertically) winter campaign an all-sky monochromatic CCD imager has been used to investigate the properties of short-period mesospheric gravity waves at high northern latitudes. Sequential measurements of several nightglow emissions were made from Esrange, Sweden, during a limited period from 27–31 January 2003. Coincident wind measurements over the altitude range (~80–100 km) using two meteor radar systems located at Esrange and Andenes have been used to perform a novel investigation of the intrinsic properties of five distinct wave events observed during this period. Additional lidar and MSIS model temperature data have been used to investigate their nature (i.e. freely propagating or ducted). Four of these extensive wave events were found to be freely propagating with potential source regions to the north of Scandinavia. No evidence was found for strong orographic forcing by short-period waves in the airglow emission layers. The fifth event was most unusual exhibiting an extensive, but much smaller and variable wavelength pattern that appeared to be embedded in the background wind field. Coincident wind measurements indicated the presence of a strong shear suggesting this event was probably due to a large-scale Kelvin-Helmholtz instability

Why don't many obese pregnant and post-natal women engage with a weight management service?

Objective: This study investigated the views and experiences of obese pregnant and post-natal women who had declined or disengaged from an evidence-based weight management service, and their reasons for doing so. Background: Despite significant risks of maternal obesity to both mother and baby, the majority of obese women offered tailored weight management support during or after pregnancy declined to use it, and many women who accepted the service disengaged soon after. Methods: Semi-structured interviews regarding women’s views and experiences were conducted with obese pregnant and post-natal women who declined the service (N = 7) and women who disengaged from the service (N = 11) and analysed thematically. Results: Four main themes were identified. ‘First contact counts’ related to inadequate explanation of the service by the referrer, being offended by the referral, and negative expectations of the service. ‘Missed opportunities for support’ describes what support declining women identified as desirable, such as regular weight monitoring. ‘No need for help’, and ‘Service not meeting needs’ related to personal choices regarding weight management, including not wanting support and preferring group-based services. Conclusions: While some obese pregnant and post-natal women did not want any type of weight management support, many did but failed to engage with the service on offer due to a variety of barriers. A more sensitive and transparent referral process and further tailoring of the service to meet individual needs may increase uptake and continued use of this service. The inclusion of non-participants and non-completers formed a valuable element of service evaluation

Selective CO₂ capture in metal-organic frameworks with azine-functionalized pores generated by mechanosynthesis

Two new three-dimensional porous Zn(II)-based metal-organic frameworks, containing azine-functionalized pores, have been readily and quickly isolated via mechanosynthesis, by using a nonlinear dicarboxylate and linear N-donor ligands. The use of nonfunctionalized and methyl-functionalized N-donor ligands has led to the formation of frameworks with different topologies and metal-ligand connectivities and therefore different pore sizes and accessible volumes. Despite this, both metal-organic frameworks (MOFs) possess comparable BET surface areas and CO₂ uptakes at 273 and 298 K at 1 bar. The network with narrow and interconnected pores in three dimensions shows greater affinity for CO compared to the network with one-dimensional and relatively large pores-attributable to the more effective interactions with the azine groups

Therapeutic Effects of Liposome-Enveloped Ligusticum chuanxiong Essential Oil on Hypertrophic Scars in the Rabbit Ear Model

Hypertrophic scarring, a common proliferative disorder of dermal fibroblasts, results from an overproduction of fibroblasts and excessive deposition of collagen. Although treatment with surgical excision or steroid hormones can modify the symptoms, numerous treatment-related complications have been described. In view of this, we investigated the therapeutic effects of essential oil (EO) from rhizomes of Ligusticum chuanxiong Hort. (Umbelliferae) on formed hypertrophic scars in a rabbit ear model. EO was prepared as a liposomal formulation (liposome-enveloped essential oil, LEO) and a rabbit ear model with hypertrophic scars was established. LEO (2.5, 5, and 10%) was applied once daily to the scars for 28 days. On postoperative day 56, the scar tissue was excised for masson's trichrome staining, detection of fibroblast apoptosis, assays of the levels of collagens I and III, and analysis of the mRNA expression of matrix metalloproteinase-1 (MMP-1), caspase-3 and -9, and transforming growth factor beta 1 (TGF-β1). In addition, the scar elevation index (SEI) was also determined. As a result, LEO treatment significantly alleviated formed hypertrophic scars on rabbit ears. The levels of TGF-β1, MMP-1, collagen I, and collagen III were evidently decreased, and caspase -3 and -9 levels and apoptosis cells were markedly increased in the scar tissue. SEI was also significantly reduced. Histological findings exhibited significant amelioration of the collagen tissue. These results suggest that LEO possesses the favorable therapeutic effects on formed hypertrophic scars in the rabbit ear model and may be an effective cure for human hypertrophic scars

Pilot parallel randomised controlled trial of protective socks against usual care to reduce skin tears in high risk people: 'STOPCUTS'.

Skin tears are common in older adults and those taking steroids and warfarin. They are traumatic, often blunt injuries caused by oblique knocks to the extremities. The epidermis may separate from the dermis or both layers from underlying tissues leaving a skin flap or total loss of tissue, which is painful and prone to infection. 'Dermatuff™' knee-length socks containing Kevlar fibres (used in stab-proof vests and motorcyclists' clothing) aim to prevent skin tears. The acceptability of the socks and the feasibility of a randomised controlled trial (RCT) had not been explored.Royal Devon & Exeter NHS Foundation TrustThis article is freely available via Open Access. Click on the Additional Link above to access the full-text via the publisher's site.NIHR Research for Patient BenefitEDGE Project ID: 1854