Somewhere In The World : Dans Un Coin Du Monde

https://digitalcommons.library.umaine.edu/mmb-vp/5335/thumbnail.jp

Crew Motion and the Dynamic Environment of Spaceborne Experiments

Analytical study of crew motion on dynamic environment of orbiting laboratorie

Evaluating Matrix Circuits

The circuit evaluation problem (also known as the compressed word problem) for finitely generated linear groups is studied. The best upper bound for this problem is $\mathsf{coRP}$, which is shown by a reduction to polynomial identity testing. Conversely, the compressed word problem for the linear group $\mathsf{SL}_3(\mathbb{Z})$ is equivalent to polynomial identity testing. In the paper, it is shown that the compressed word problem for every finitely generated nilpotent group is in $\mathsf{DET} \subseteq \mathsf{NC}^2$. Within the larger class of polycyclic groups we find examples where the compressed word problem is at least as hard as polynomial identity testing for skew arithmetic circuits

Locally Chain-Parsable Languages

If a context-free language enjoys the local parsability property then, no matter how the source string is segmented, each segment can be parsed in- dependently, and an efficient parallel parsing algorithm becomes possible. The new class of locally chain-parsable languages (LCPL), included in deterministic context-free languages, is here defined by means of the chain-driven automa- ton and characterized by decidable properties of grammar derivations. Such au- tomaton decides to reduce or not a factor in a way purely driven by the terminal characters, thus extending the well-known concept of Input-Driven (ID) (visibly) pushdown machines. LCPL extend and improve the practically relevant operator- precedence languages (Floyd), which are known to strictly include the ID lan- guages, and for which a parallel-parser generator exists. Consistently with the classical results for ID, chain-compatible LCPL are closed under reversal and Boolean operations, and language inclusion is decidable

RNAi phenotype profiling of kinases identifies potential therapeutic targets in Ewing's sarcoma

<p>Abstract</p> <p>Background</p> <p>Ewing's sarcomas are aggressive musculoskeletal tumors occurring most frequently in the long and flat bones as a solitary lesion mostly during the teen-age years of life. With current treatments, significant number of patients relapse and survival is poor for those with metastatic disease. As part of novel target discovery in Ewing's sarcoma, we applied RNAi mediated phenotypic profiling to identify kinase targets involved in growth and survival of Ewing's sarcoma cells.</p> <p>Results</p> <p>Four Ewing's sarcoma cell lines TC-32, TC-71, SK-ES-1 and RD-ES were tested in high throughput-RNAi screens using a siRNA library targeting 572 kinases. Knockdown of 25 siRNAs reduced the growth of all four Ewing's sarcoma cell lines in replicate screens. Of these, 16 siRNA were specific and reduced proliferation of Ewing's sarcoma cells as compared to normal fibroblasts. Secondary validation and preliminary mechanistic studies highlighted the kinases STK10 and TNK2 as having important roles in growth and survival of Ewing's sarcoma cells. Furthermore, knockdown of STK10 and TNK2 by siRNA showed increased apoptosis.</p> <p>Conclusion</p> <p>In summary, RNAi-based phenotypic profiling proved to be a powerful gene target discovery strategy, leading to successful identification and validation of STK10 and TNK2 as two novel potential therapeutic targets for Ewing's sarcoma.</p

Plasmas and Controlled Nuclear Fusion

Contains reports on ten research projects split into three sections.National Science Foundation (Grant GK-2581

Effect of the GaAsP shell on optical properties of self-catalyzed GaAs nanowires grown on silicon

We realize growth of self-catalyzed core-shell GaAs/GaAsP nanowires (NWs) on Si substrates using molecular-beam epitaxy. Transmission electron microscopy (TEM) of single GaAs/GaAsP NWs confirms their high crystal quality and shows domination of the zinc-blende phase. This is further confirmed in optics of single NWs, studied using cw and time-resolved photoluminescence (PL). A detailed comparison with uncapped GaAs NWs emphasizes the effect of the GaAsP capping in suppressing the non-radiative surface states: significant PL enhancement in the core-shell structures exceeding 2000 times at 10K is observed; in uncapped NWs PL is quenched at 60K whereas single core-shell GaAs/GaAsP NWs exhibit bright emission even at room temperature. From analysis of the PL temperature dependence in both types of NW we are able to determine the main carrier escape mechanisms leading to the PL quench

Filling a blank on the map: 60 years of fisheries in Equatorial Guinea

Despite a scarcity of pertinent information, it has been possible to reconstruct time series of marine fisheries catches for Equatorial Guinea from 1950 to 2010 using per capita fish consumption and population numbers for small-scale fisheries, catch rates and number of vessels for industrial fisheries and discard rates to estimate the discarded bycatch. Small-scale fisheries, industrial large-scale fisheries, domestic and legal and illegal foreign fisheries and their discards are all included. Total catches were estimated at 2.7 million tonnes over the time period considered, of which 653 000 t were caught domestically compared to 187 000 t reported by FAO. This shows that fisheries have more importance for Equatorial Guinea's food security than the official data suggest. In contrast to what is suggested by official figures, fisheries were shown to be strongly impacted by civil and political unrest; notably, they declined overall because of civil and political conflicts, socio-demographic dynamics, and a growing role of the newly discovered oil resources, which directly and indirectly threaten the food security of the people of Equatorial Guinea

Beyond sequential presentation: Misconceptions and misrepresentations of sequential lineups

Malpass, Tredoux, and McQuiston-Surrett (2009), hereinafter 'MTM', provide comments on the sequential lineup, research comparing sequential and simultaneous lineups, and the policy implications of this literature. We will comment on points of agreement and disagreement. First, we agree with the following: (1) Peer review, publication of results, and diversity of methods, procedures, and subject populations significantly contribute to the value of research as a basis both for psychological understanding and for recommended policy. (2) Absence of error, omission, and confounds make interpretation and application easier. These conclusions are not revolutionary but seem to occupy a great deal of MTM's thinking. We disagree with many things that MTM have to say but have room here only to address a few.div_PaS14pub3253pub