924 research outputs found

    Child Murder: A Re-examination Of Durkheim\u27s Theory Of Homicide

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    The current study examines county-level characteristics and their impact on child homicide. This work uses Durkheimian theory and tests the concept of solidarity by using variables that constitute integration and regulation. In addition, some variables are drawn from other theoretical perspectives, mainly social disorganization and anomie theories, to better explore additional macro-level indicators. Data were obtained from multiple locations. Homicide data for children, from birth through five years, utilized in this work came from the National Incident-Based Reporting System. County level socio-demographics were obtained from the Census. Political party affiliation (Republican or Democrat) came from Politico, and religious data were collected by InfoGroup and organized into groups by the Association of Religion Data Archives. This study aims to increase our understanding of how macro-level contextual and situational factors may help guide policy makers, law enforcement personnel, and any other individuals who are concerned with areas where there are varying degrees of risk for child homicid

    An Overview and Critique of NCAA Policy Regarding the Use of Sport Psychology Consultants at the Division I Level

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    Over the past 20 years the National Collegiate Athletic Association Division-I (NCAA) has restricted the activities of sport psychology consultants (SPCs) working with student-athletes, particularly at the Division I (D-I) level. In some cases, the restrictions have been based on the assumption that what SPCs do is actually “coaching.” Thus, if SPCs are permitted to interact with student-athletes during practices and competitions they must be considered as “countable” coaches. In this paper, we briefly discuss the history of NCAA rules governing the activities of SPCs, provide excerpts from the sport psychology literature and the NCAA D-I Manual that illustrate how the specialized work of SPCs is different from that of coaches, suggest reasons why allowing student-athletes and coaches access to SPCs during practices and competitions would be beneficial to both groups, and propose ways NCAA legislation might be amended to allow SPCs to work with student-athletes in a manner similar to the ways other athletic department support personnel (e.g., athletic trainers and strength and conditioning coaches) are permitted to do

    Navigating Rough Waters: Public Swimming Pools, Discrimination, and the Law

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    Historically, swimming pools have been a focal point of racial tension. Discrimination and segregation are inextricably tied to the history of public swimming usage in the United States. Pools are public spaces that are physically and visually intimate. History has revealed that both de jure (enacted through the law by the government) and de facto (occurs through social interaction) discrimination have contributed to segregatory practices in the United States. The purpose of this article is twofold: 1) to examine the social pattern of discrimination that has stymied the growth of swimming in communities of color in the United States; and 2) to examine key legal cases that helped to mitigate discriminatory practices in the use of public swimming pools in the United States. Landmark cases such as Plessy v. Ferguson, Brown v. Topeka, and Dawson v. Mayor and City Council of Baltimore each helped to cast a bright light on the practice of segregation and public swimming pools. In spite of the history of discrimination and segregation relative to public swimming pools in the United States, citizens, stakeholder groups and professional associations must be advocates to ensure that public pools are protected and that the patterns of discrimination and “neuvo-segregation” do not persist

    Inflammation as a Central Mechanism in Alzheimer\u27s Disease

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    Alzheimer\u27s disease (AD) is a progressive neurodegenerative disorder that is characterized by cognitive decline and the presence of two core pathologies, amyloid β plaques and neurofibrillary tangles. Over the last decade, the presence of a sustained immune response in the brain has emerged as a third core pathology in AD. The sustained activation of the brain\u27s resident macrophages (microglia) and other immune cells has been demonstrated to exacerbate both amyloid and tau pathology and may serve as a link in the pathogenesis of the disorder. In the following review, we provide an overview of inflammation in AD and a detailed coverage of a number of microglia-related signaling mechanisms that have been implicated in AD. Additional information on microglia signaling and a number of cytokines in AD are also reviewed. We also review the potential connection of risk factors for AD and how they may be related to inflammatory mechanisms

    Racist or Radical? The Strange Case of Robert Moses and the Building of New York City\u27s Aquatics Infrastructure

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    Who was Robert Moses? In this article, we want to cast a bright light on Robert Moses as a visionary urban planner, which included the comprehensive planning of the outdoor and indoor aquatic infrastructure for New York City. Second, we want to highlight some of his administration\u27s significant accomplishments and challenges in providing aquatics opportunities for diverse populations, including people of color. Finally, we aspire to illustrate what happens when officials with power and authority in local government are permitted to operate without scrutiny and are unbeholden to a meaningful series of checks and balances. Robert Moses’ tenure as a 40-year-plus appointed public official highlighted the need for accountability in public service. During his expansive career, Moses held more than 12 bureaucratic appointments, sometimes concurrently, allowing him to drive his infrastructure development agenda funded by the WPA mercurially. His herculean list of accomplishments included parks, highways, 11 large swimming pools, civic centers, sports stadiums, 13 bridges, 658 playgrounds, 416 miles of parkway, 150,000 units of public housing, and the 1964-65 World’s Fair, which cost in today\u27s economy approximately $150 billion (Adiv, 2015). One of the central jewels in the crown of his accomplishments was the planning, design, and construction of the outdoor and indoor swimming infrastructure of New York City. Unfortunately, many of Moses\u27 achievements were overshadowed by allegations of racial politics, a lack of accountability for his decisions and policy actions, and reports of his disdain for blacks, Puerto Ricans, and low-income people. He was also called dictatorial, power-hungry, and vindictive during his long tenure in public service. Moses was rebuked for his lack of inclusion in planning processes and making resource allocation decisions based on the racial composition of a community

    An experimental design approach to the chemical characterisation of pectin polysaccharides extracted from Cucumis melo Inodorus

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    Extracted pectins have been utilised in a number of applications in both the food and pharmaceutical industries where they are generally used as gelling agents, thickeners and stabilisers, although a number of pectins have been shown to be bioactive. These functional properties will depend upon extraction conditions. A statistical experimental design approach was used to study the effects of extraction conditions pH, time and temperature on pectins extracted from Cucumis melo Inodorus. The results show that the chemical composition is very sensitive to these conditions and that this has a great influence on for example the degree of branching. Higher temperatures, lower pHs and longer extraction times lead to a loss of the more acid labile arabinofuranose residues present on the pectin side chain. The fitting of regression equations relating yield and composition to extraction conditions can therefore lead to tailor-made pectins for specific properties and/ or applications

    Carbohydrate-active enzymes exemplify entropic principles in metabolism

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    Statistical thermodynamics and in vitro experimentation demonstrate that metabolic enzymes can be driven by an increase in the entropy of a reaction system, and point to a role for entropy gradients in the emergence of robust metabolic functions in vivo

    Traumatic brain injury in hTau model mice: Enhanced acute macrophage response and altered long-term recovery

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    TBI induces widespread neuroinflammation and accumulation of microtubule associated protein tau (MAPT) - two key pathological features of tauopathies. This study sought to characterize the microglial/macrophage response to TBI in genomic-based MAPT transgenic mice in a Mapt knockout background (called hTau). Two-month-old hTau and age-matched control male and female mice received a single lateral fluid percussion TBI or sham injury. Separate groups of mice were aged to an acute (3 days post-injury [DPI]) or chronic (135 DPI) post-injury time point. As judged by tissue immunostaining for macrophage markers, microglial/macrophage response to TBI was enhanced at 3 DPI in hTau mice compared to control TBI and sham mice. However, MAPT phosphorylation increased in hTau mice regardless of injury group. Flow cytometric analysis revealed distinct populations of microglia and macrophages within all groups at 135 DPI. Unexpectedly, microglial reactivity was significantly reduced in hTau TBI mice compared to all other groups. Instead, hTau TBI mice showed a persistent macrophage response. In addition, TBI enhanced MAPT pathology in the temporal cortex and hippocampus of hTau TBI mice compared to controls 135 DPI. A battery of behavioral test revealed that TBI in hTau mice resulted in compromised use of spatial search strategies to complete a water maze task despite lack of motor or visual deficits. Collectively, these data indicate that the presence of wild-type human tau alters the microglial/macrophage response to a single TBI, induces delayed, region-specific MAPT pathology, and alters cognitive recovery; however, the causal relationship between these events remains unclear. These results highlight the potential significance of communication between MAPT and microglia/macrophages following TBI and emphasize the role of neuroinflammation in post-injury recovery

    Citizen Engagement in Aquatics Equity: The Case of Winston Waterworks

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    Historically, swimming pools have been a source of inequity when it comes to the distribution of recreation services in the United States. Many of the problems that correlate with the inequitable allocation of recreation resources including public swimming pools began with ideas about race, geography, poor planning practices and faulty policymaking (Rothstein, 2017). Moreover, one of the primary outcomes of engaged, inclusive planning is equity in the provision of recreation programs and facilities. In this essay, we offer a summary of key legal cases that help address questions related resource allocation related to public swimming pools. Finally, we present a short case study on the Winston Water Works Project in Winston-Salem, North Carolina. This case illustrates the power of grassroots level advocacy, engaged community planning, and policymaking that protects the recreation infrastructure in a community and moves the needle of social justice toward equity. Our principle interest in this paper is in the equitable provision and distribution of aquatics programming and facilities
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