Unitarity analysis of general Born-Infeld gravity theories

We develop techniques of analyzing the unitarity of general Born-Infeld (BI) gravity actions in D-dimensional spacetimes. Determinantal form of the action allows us to find a compact expression quadratic in the metric fluctuations around constant curvature backgrounds. This is highly nontrivial since for the BI actions, in principle, infinitely many terms in the curvature expansion should contribute to the quadratic action in the metric fluctuations around constant curvature backgrounds, which would render the unitarity analysis intractable. Moreover in even dimensions, unitarity of the theory depends only on finite number of terms built from the powers of the curvature tensor. We apply our techniques to some four-dimensional examples.Comment: 26 pages, typos corrected, version to appear in Phys. Rev.

Banach lattices of L-weakly and M-weakly compact operators

We give conditions for the linear span of the positive L-weakly compact (resp. M-weakly compact) operators to be a Banach lattice under the regular norm, for that Banach lattice to have an order continuous norm, to be an AL-space or an AM-space.Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [2219]; Research Foundation of Namik Kemal UniversityNamik Kemal University [NKUBAP.00.10.AR.15.04]The first author was supported by The Scientific and Technological Research Council of Turkey (TUBITAK) within the context of 2219-Post Doctoral Fellowship Program and by the Research Foundation of Namik Kemal University (Project No. NKUBAP.00.10.AR.15.04.)

Shortcuts to high symmetry solutions in gravitational theories

We apply the Weyl method, as sanctioned by Palais' symmetric criticality theorems, to obtain those -highly symmetric -geometries amenable to explicit solution, in generic gravitational models and dimension. The technique consists of judiciously violating the rules of variational principles by inserting highly symmetric, and seemingly gauge fixed, metrics into the action, then varying it directly to arrive at a small number of transparent, indexless, field equations. Illustrations include spherically and axially symmetric solutions in a wide range of models beyond D=4 Einstein theory; already at D=4, novel results emerge such as exclusion of Schwarzschild solutions in cubic curvature models and restrictions on ``independent'' integration parameters in quadratic ones. Another application of Weyl's method is an easy derivation of Birkhoff's theorem in systems with only tensor modes. Other uses are also suggested.Comment: 10 page

Photonuclear reactions with Zinc: A case for clinical linacs

The use of bremsstrahlung photons produced by a linac to induce photonuclear reactions is wide spread. However, using a clinical linac to produce the photons is a new concept. We aimed to induce photonuclear reactions on zinc isotopes and measure the subsequent transition energies and half-lives. For this purpose, a bremsstrahlung photon beam of 18 MeV endpoint energy produced by the Philips SLI-25 linac has been used. The subsequent decay has been measured with a well-shielded single HPGe detector. The results obtained for transition energies are in good agreement with the literature data and in many cases surpass these in accuracy. For the half-lives, we are in agreement with the literature data, but do not achieve their precision. The obtained accuracy for the transition energies show what is achievable in an experiment such as ours. We demonstrate the usefulness and benefits of employing clinical linacs for nuclear physics experiments

Gravitating Instantons In 3 Dimensions

We study the Einstein-Chern-Simons gravity coupled to Yang-Mills-Higgs theory in three dimensional Euclidean space with cosmological constant. The classical equations reduce to Bogomol'nyi type first order equations in curved space. There are BPS type gauge theory instanton (monopole) solutions of finite action in a gravitational instanton which itself has a finite action. We also discuss gauge theory instantons in the vacuum (zero action) AdS space. In addition we point out to some exact solutions which are singular.Comment: 17 pages, 4 figures, title has changed, gravitational instanton actions are adde

Energy in Generic Higher Curvature Gravity Theories

We define and compute the energy of higher curvature gravity theories in arbitrary dimensions. Generically, these theories admit constant curvature vacua (even in the absence of an explicit cosmological constant), and asymptotically constant curvature solutions with non-trivial energy properties. For concreteness, we study quadratic curvature models in detail. Among them, the one whose action is the square of the traceless Ricci tensor always has zero energy, unlike conformal (Weyl) gravity. We also study the string-inspired Einstein-Gauss-Bonnet model and show that both its flat and Anti-de-Sitter vacua are stable.Comment: 18 pages, typos corrected, one footnote added, to appear in Phys. Rev.

A novel thiazolidine compound induces caspase-9 dependent apoptosis in cancer cells

Cataloged from PDF version of article.The forward chemogenomics strategy allowed us to identify a potent cytotoxic thiazolidine compound as an apoptosis-inducing agent. Chemical structures were designed around a thiazolidine ring, a structure already noted for its anticancer properties. Initially, we evaluated these novel compounds on liver, breast, colon and endometrial cancer cell lines. The compound 3 (ALC67) showed the strongest cytotoxic activity (IC50 ∼5 μM). Cell cycle analysis with ALC67 on liver cells revealed SubG1/G1 arrest bearing apoptosis. Furthermore we demonstrated that cytotoxicity of this compound was due to the activation of caspase-9 involved apoptotic pathway, which is death receptor independent. © 2012 Elsevier Ltd. All rights reserve

Yang-Mills Solutions on Euclidean Schwarzschild Space

We show that the apparently periodic Charap-Duff Yang-Mills `instantons' in time-compactified Euclidean Schwarzschild space are actually time independent. For these solutions, the Yang-Mills potential is constant along the time direction (no barrier) and therefore, there is no tunneling. We also demonstrate that the solutions found to date are three dimensional monopoles and dyons. We conjecture that there are no time-dependent solutions in the Euclidean Schwarzschild background.Comment: 12 pages, references added, version to appear in PR

Turner syndrome and associated problems in turkish children: A multicenter study

Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosi) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto’s thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. © Journal of Clinical Research in Pediatric Endocrinology

Calorons in Weyl Gauge

We demonstrate by explicit construction that while the untwisted Harrington-Shepard caloron $A_\mu$ is manifestly periodic in Euclidean time, with period $\beta=\frac{1}{T}$, when transformed to the Weyl ($A_0=0$) gauge, the caloron gauge field $A_i$ is periodic only up to a large gauge transformation, with winding number equal to the caloron's topological charge. This helps clarify the tunneling interpretation of these solutions, and their relation to Chern-Simons numbers and winding numbers.Comment: 10 pages, 10 figures, a sign typo in equation 27 is correcte