La imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia, Bogotá, D.C.

Con el presente informe se plantea la creación de unas estrategias que promuevan el empoderamiento, afrontamiento y resiliencia de las realidades de las víctimas del conflicto armado en Colombia, especialmente los desplazados y exiliados, mediante el análisis del relato de dos víctimas de este conflicto se identifican los aspectos psicosociales emergentes y cómo han logrado afrontar los hechos de violencia sufridos. En los relatos de historias que retornan, se analiza el video de la Comisión de la verdad “Historias que retornan capítulo 4 – Nelson”, víctima de secuestro y extorsión quien sale del país y se reconoce como víctima, exiliado y sobreviviente. Como estrategia se plantean unas preguntas de tipo circular, reflexivo y estratégico, con las cuales se busca que el protagonista descubra su realidad y proyecte acciones de bienestar emocional. En la segunda actividad del informe, se analiza el video “Masacre en El Salado” Relatos de resiliencia después de 20 años, a través de un análisis se identifican los emergentes psicosociales y los impactos bio-psico-socioculturales, y se trazan estrategias de afrontamiento y los recursos para generar alternativas de solución de los conflictos. Como última actividad se comparte la herramienta Foto-Voz realizada desde la mirada colaborativa en los escenarios de violencia seleccionados en la ciudad de Bogotá y las conclusiones del trabajo realizado.This report proposes the creation of strategies that promote empowerment, coping and resilience of the realities of the victims of the armed conflict in Colombia, especially the displaced and exiled, through the analysis of the story of two victims of this conflict are identified the emerging psychosocial aspects and how they have managed to deal with the acts of violence suffered. In the accounts of stories that return, the video of the Truth Commission "Stories that return chapter 4 - Nelson" is analyzed, a victim of kidnapping and extortion who leaves the country and recognizes himself as a victim, exile and survivor. As a strategy, circular, reflexive and strategic questions are posed, with which the protagonist discovers his reality and projects emotional well-being actions. In the second activity of the report, the video "Massacre in El Salado" Stories of resilience after 20 years is analyzed, through an analysis the emerging psychosocial and bio-psycho-sociocultural impacts are identified, and coping strategies are outlined. and the resources to generate alternative solutions to conflicts. As a last activity, the Photo-Voice tool carried out from the collaborative perspective in the selected violence scenarios in the City of Bogotá and the conclusions of the work carried out are shared

Comparación de regiones hipervariables del gen rRNA 16S para el estudio de la microbiota intestinal en acuicultura

Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects for farmed fish, so its potential on the skin needs to be studied more deeply. The wounded specimens that received the diet with SpPdp11 showed a decrease in the abundance of Enterobacteriaceae, Photobacterium and Achromobacter related to bacterial biofilm formation, as well as the overexpression of genes involved in signaling mechanisms (itpr3), cell migration and differentiation (panxa, ttbk1a, smpd3, vamp5); and repression of genes related to cell proliferation (vstm4a, areg), consistent with a more efficient skin healing processes than that observed in the wounded control group. In addition, among the groups of damaged skin with different diets, Achromobacter, f_Ruminococcaceae, p_Bacteroidetes, Fluviicola and Flavobacterium genera with significant differences showed positive correlations with genes related to cell migration and negative correlations with inflammation and cell proliferation and may be the target of future studies.Este estudio fue apoyado por subvenciones del Ministerio de Economía y Competitividad (MINECO) (AGL-2017-83370-C1-R y AGL-2017-83370-C3-R). Partial funding for open access charge: Universidad de Málag

Construction of miRNA-mRNA networks for the identification of lung cancer biomarkers in liquid biopsies.

Lung cancer (LC) is the most common cause of cancer death worldwide mostly due to the low survival rate: 75% of cases are identified in advanced stages. In this study, the list of useful biomarkers to make an early diagnosis using liquid biopsies was expanded. A total of 30 samples of LC were analyzed to define potential miRNA biomarkers in liquid biopsies for LC. The biomarkers have been identified in interaction networks miRNA-mRNA. The potential biomarkers have been then validated in large cohorts. A total of 15 candidate miRNAs, that regulate the repression of 30 mRNAs, have been identified as a specific functional interaction network for squamous carcinoma, while the specific functional interaction network of adenocarcinoma consists of four candidate miRNAs that seem to handle the repression of five mRNA. Inspection of expression levels in larger cohorts validates the usefulness of the 11 candidates as biomarkers in liquid biopsies. The 11 candidate miRNAs found could be utilized to form diagnostic predictive biomarkers for LC in liquid biopsies

Social and environmental factors in the diversity of tomato landraces from the South-Central region of Mexico

ABSTRACT: In the present study, we investigated the influence of social and environmental factors in the genetic diversity of tomato landraces in the South-Central region of Mexico. A total of 30 tomato landraces, collected in 18 villages with different ethnolinguistic affiliations, were analyzed. We reported that the genetic diversity of tomato landraces is associated with the ethnolinguistic group, weather, and soil-type present in the region studied. Our results showed that there are morphological differences between landraces grown by different ethnolinguistic groups; however, there was also evidence of morphological similarities between landraces from groups with different ethnolinguistic affiliations. Finally, different selection criteria, mainly fruit color, size and shape, plays an important role in the phenotypic divergence among landraces grown in different traditional farming systems

Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries

Background Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks. Methods The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned. Results A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31). Conclusion Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)