1,111 research outputs found

    Creating value in online communities: the sociomaterial configuring of strategy, platform, and stakeholder engagement

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    How is value created in an online community (OC) over time? We explored this question through a longitudinal field study of an OC in the healthcare arena. We found that multiple kinds of value were produced and changed over time as different participants engaged with the OC and its evolving technology in various ways. To explain our findings, we theorize OC value as performed through the ongoing sociomaterial configuring of strategies, digital platforms, and stakeholder engagement. We develop a process perspective to explain these dynamics and identify multiple different kinds of value being created by an OC over time: financial, epistemic, ethical, service, reputational, and platform. Our research points to the importance of expanding the notion of OC users to encompass a broader understanding of stakeholders. It further suggests that creating OC value increasingly requires going beyond a dyadic relationship between the OC and the firm to encompassing a more complex relationship involving a wider ecosystem of stakeholders.Eivor Oborn is part-funded/supported by the National Institute for Health Research (NIHR) Collaborations for Leadership in Applied Health Research and Care West Midlands

    Episode 1: Knowledge Management and Analytics with Dr. Jay Liebowitz

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    If you are interested in Knowledge Management and Analytics, this podcast will be an enlightening experience for you. Join University Libraries as we interview Dr. Jay Liebowitz, a Visiting Professor of the Stillman School of Business at Seton Hall and one of most highly ranked in knowledge management strategy. The interview covered, among other topics, Dr. Liebowitz’s newest book: A Research Agenda for Knowledge Management and Analytics

    Trajectory dynamics in innovation: developing and transforming a mobile money service across time and place

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    This paper examines how and why innovations are reshaped as they become implemented and used in locales that are distant and distinct from those where the innovation was initially developed. Drawing on an in-depth field study of the innovation process that produced a mobile money system for Kenya, we contribute an understanding of the particular dynamics that arise when an innovation trajectory interacts with local trajectories that constitute the local conditions and practices of specific places. We identify four distinct patterns of trajectory dynamics — separation, coordination, diversification, and integration — each of which has different implications for the innovation, its implementation, and consequences on the ground. Developing a model of trajectory dynamics in innovation, we theorize the processes through which innovations are transformed over time as they interact with multiple local trajectories, and the specific innovation outcomes that are generated as a result. Such theorizing reconceptualizes traditional notions of innovation diffusion by explicating how and why innovations change in multiple and unexpected ways as they move to particular places and engage with local conditions and practices

    Microscopic correlation between chemical and electronic states in epitaxial graphene on SiC(000-1)

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    We present energy filtered electron emission spectromicroscopy with spatial and wave-vector resolution on few layer epitaxial graphene on SiC$(000-1) grown by furnace annealing. Low energy electron microscopy shows that more than 80% of the sample is covered by 2-3 graphene layers. C1s spectromicroscopy provides an independent measurement of the graphene thickness distribution map. The work function, measured by photoelectron emission microscopy (PEEM), varies across the surface from 4.34 to 4.50eV according to both the graphene thickness and the graphene-SiC interface chemical state. At least two SiC surface chemical states (i.e., two different SiC surface structures) are present at the graphene/SiC interface. Charge transfer occurs at each graphene/SiC interface. K-space PEEM gives 3D maps of the k_|| pi - pi* band dispersion in micron scale regions show that the Dirac point shifts as a function of graphene thickness. Novel Bragg diffraction of the Dirac cones via the superlattice formed by the commensurately rotated graphene sheets is observed. The experiments underline the importance of lateral and spectroscopic resolution on the scale of future electronic devices in order to precisely characterize the transport properties and band alignments

    Justifying health IT investments: a process model of framing practices and reputational value

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    Despite important research contributions on the financial and operational dimensions of information technology (IT) value, justifying health IT (HIT) investments remains a difficult and enduring issue for IT managers. Recent work has expanded our understanding of HIT value, by focusing on the initial resource allocation stage, and through conceptualizations of value across multiple dimensions. Building on these developments, we adopt a performative perspective to examine the research question of how practitioners justify early stage HIT investments, with a focus on reputational value. We explored this question through a comparative field study of two hospital organizations in the English National Health Service (NHS). We found that practitioners' temporally orientated framing practices matter in justifying HIT investments, enacting different possibilities for reputational value. We develop a process model to explain these dynamics and highlight the mutability of reputational value, which can lead to different possibilities for restoring, enhancing, or maintaining reputation. We conclude by discussing the implications for justifying HIT investments.Stavros was supported by a scholarship from the Economic and Social Research Council (Grant Number: 1491536). Eivor Oborn was supported by the National Institute for Health Research (NIHR) Collaborations for Leadership in Applied Health Research and Care West Midlands

    Decoupling of economic growth and emissions in China’s cities: A case study of the Central Plains urban agglomeration

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    Recently, the economy has grown rapidly in China’s Central Plains urban agglomeration, with high energy consumption and a huge pressure on reducing CO2 emissions. Thus, low-carbon development is an important measure to solve economic, energy and environmental problems. To analyse low-emission development, this paper clarifies the evolutionary characteristics of CO2 emissions and the decoupling relationship between GDP and CO2 emissions based on the latest available data from 2000 to 2015. The results indicate that CO2 emissions of Pingdingshan and Changzhi are higher in the same year. The ratios from coal consumption accounting for the total CO2 emissions are clearly bigger than from other energy types and industrial processes. Changzhi, Luoyang and Pingdingshan have reached their peaks. Five cities have experienced strong decoupling after 2010, 13 cities present weak decoupling, 4 cities present growth connection, and 7 cities show growth negative decoupling. It can be concluded that a relatively smaller proportion of industry and strict policy implementations of coal reduction are the main factors in inhibiting the decoupling. So the proportion of coal purification should be increased firstly. Then, the energy consumption structure should be changed from the traditional coal consumption structure to coal, oil and gas. Lastly, economic means can be used to control CO2 emissions

    Benznidazole biotransformation and multiple targets in <i>Trypanosoma</i> cruzi revealed by metabolomics

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    &lt;b&gt;Background&lt;/b&gt;&lt;p&gt;&lt;/p&gt; The first line treatment for Chagas disease, a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi, involves administration of benznidazole (Bzn). Bzn is a 2-nitroimidazole pro-drug which requires nitroreduction to become active, although its mode of action is not fully understood. In the present work we used a non-targeted MS-based metabolomics approach to study the metabolic response of T. cruzi to Bzn.&lt;p&gt;&lt;/p&gt; &lt;b&gt;Methodology/Principal findings&lt;/b&gt;&lt;p&gt;&lt;/p&gt; Parasites treated with Bzn were minimally altered compared to untreated trypanosomes, although the redox active thiols trypanothione, homotrypanothione and cysteine were significantly diminished in abundance post-treatment. In addition, multiple Bzn-derived metabolites were detected after treatment. These metabolites included reduction products, fragments and covalent adducts of reduced Bzn linked to each of the major low molecular weight thiols: trypanothione, glutathione, Îł-glutamylcysteine, glutathionylspermidine, cysteine and ovothiol A. Bzn products known to be generated in vitro by the unusual trypanosomal nitroreductase, TcNTRI, were found within the parasites, but low molecular weight adducts of glyoxal, a proposed toxic end-product of NTRI Bzn metabolism, were not detected.&lt;p&gt;&lt;/p&gt; &lt;b&gt;Conclusions/significance&lt;/b&gt;&lt;p&gt;&lt;/p&gt; Our data is indicative of a major role of the thiol binding capacity of Bzn reduction products in the mechanism of Bzn toxicity against T. cruzi

    China CO2 emission accounts 1997–2015

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    China is the world’s top energy consumer and CO2 emitter, accounting for 30% of global emissions. Compiling an accurate accounting of China’s CO2 emissions is the first step in implementing reduction policies. However, no annual, officially published emissions data exist for China. The current emissions estimated by academic institutes and scholars exhibit great discrepancies. The gap between the different emissions estimates is approximately equal to the total emissions of the Russian Federation (the 4th highest emitter globally) in 2011. In this study, we constructed the time-series of CO2 emission inventories for China and its 30 provinces. We followed the Intergovernmental Panel on Climate Change (IPCC) emissions accounting method with a territorial administrative scope. The inventories include energy-related emissions (17 fossil fuels in 47 sectors) and process-related emissions (cement production). The first version of our dataset presents emission inventories from 1997 to 2015. We will update the dataset annually. The uniformly formatted emission inventories provide data support for further emission-related research as well as emissions reduction policy-making in China

    Ferroelectricity in a quasiamorphous ultrathin BaTiO3 film

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    Until now, the quasiamorphous (QA) phase in BaTiO3 (BTO), SrTiO3 (STO), and BaZrO3 was achieved by pulling a thick film through a steep temperature gradient. Here, we show that a room-temperature deposited ultrathin film, subsequently annealed in O-2 can also produce a QA phase. The atomic, electronic, and ferroelectric (FE) structure of a QA, ultrathin BTO grown on STO were studied by x-ray diffraction (XRD), x-ray photoelectron diffraction (XPD), x-ray photoelectron spectroscopy (XPS), and piezoforce microscopy (PFM). The absence of long-range order is confirmed by in-and out-of-plane XRD as well as Ti 2p XPD. FE polarized domains with good retention have been successfully written into the QA film and exhibit a clear P-E hysteresis loop. Substrate clamping frustrates volume expansion during annealing leading to a QA film. Photoelectron spectroscopy confirms a similar overall electronic structure as for thicker films but with some significant differences. Simple charge-transfer arguments are not sufficient to explain the high-resolution core-level spectra. Ba, Ti, and O all show components associated with a surface region. We suggest that the observation of such a component in the Ti 2p spectrum is linked with the high dynamic charge tensor induced by the large off-center displacement of the Ti ion.8420French National Research Agency (ANR) [ANR-10-BLAN-1012]CEAFrench National Research Agency (ANR) [ANR-10-BLAN-1012
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