177 research outputs found
Outcasts of the Gods? The Struggle over Slavery in New Zealand
In some ways, Hazel Petrieâs new book is an enigma. Having read it, readers might have a problem in pin-pointing just what constituted the âstruggleâ over slavery in MÄori New Zealand. Were inter-MÄori wars fought to end the practice
Farmacotecnia de las hojas de coca
El principio activo mĂĄs importante de la Coca, que fuera aislado por Goedeke en 1855 y mejor estudiado por Niemann en 1859, dĂĄndole el nombre que aun lleva -cocaĂna-, sĂłlo llegĂł a usarse como anestĂ©sico local en 1884, despuĂ©s de los trabajos de Carlos Koller sobre su aplicaciĂłn en OftalmologĂa.
Conocidas las extraordinarias propiedades anestĂ©sicas de este alcaloide, empezaron a usarse las soluciones extractivas de la coca, para el tratamiento de los estados inflamatorios y dolorosos de las mucosas, especialmente de la boca y la faringe, como una tĂ©cnica sencilla, prĂĄctica y poco peligrosa para aprovechar dichas virtudes terapĂ©uticas. La droga fuĂ© adquiriendo rĂĄpidamente importancia terapĂ©utica y las Farmacopeas y los Formularios Oficiales, asĂ como los tratados de TerapĂ©utica, fueron incorporĂĄndola entre - sus monografĂas, haciendo de la CocaĂna el prototipo del anestĂ©sico local.
Los textos de FarmacologĂa y los Formularios terapĂ©uticos en general, describen las propiedades y los usos terapĂ©uticos de la coca y de su principal alcaloide, la cocaĂna. Los mĂĄs antiguos citan el uso terapĂ©utico de la droga madre, en sus diversas formas farmacĂ©uticas, ya sea para uso interno (polvos, elixires, extractos, tinturas, vinos, etc), para uso externo (colutorios, gargarismos, etc). Entre los extractivos usados se mencionan la infusiĂłn y el cocimiento, pero no manifiestan un criterio definido sobre su valor terapĂ©utico ni sobre la concentraciĂłn de los mismos.Tesis digitalizada en SEDICI gracias a la Biblioteca Central de la Facultad de Ciencias Exactas (UNLP).Al momento de presentaciĂłn de esta tesis, la actual Facultad de Ciencias Exactas se denominaba Facultad de QuĂmica y Farmacia.Facultad de Ciencias Exacta
Farmacotecnia de las hojas de coca
El principio activo mĂĄs importante de la Coca, que fuera aislado por Goedeke en 1855 y mejor estudiado por Niemann en 1859, dĂĄndole el nombre que aun lleva -cocaĂna-, sĂłlo llegĂł a usarse como anestĂ©sico local en 1884, despuĂ©s de los trabajos de Carlos Koller sobre su aplicaciĂłn en OftalmologĂa.
Conocidas las extraordinarias propiedades anestĂ©sicas de este alcaloide, empezaron a usarse las soluciones extractivas de la coca, para el tratamiento de los estados inflamatorios y dolorosos de las mucosas, especialmente de la boca y la faringe, como una tĂ©cnica sencilla, prĂĄctica y poco peligrosa para aprovechar dichas virtudes terapĂ©uticas. La droga fuĂ© adquiriendo rĂĄpidamente importancia terapĂ©utica y las Farmacopeas y los Formularios Oficiales, asĂ como los tratados de TerapĂ©utica, fueron incorporĂĄndola entre - sus monografĂas, haciendo de la CocaĂna el prototipo del anestĂ©sico local.
Los textos de FarmacologĂa y los Formularios terapĂ©uticos en general, describen las propiedades y los usos terapĂ©uticos de la coca y de su principal alcaloide, la cocaĂna. Los mĂĄs antiguos citan el uso terapĂ©utico de la droga madre, en sus diversas formas farmacĂ©uticas, ya sea para uso interno (polvos, elixires, extractos, tinturas, vinos, etc), para uso externo (colutorios, gargarismos, etc). Entre los extractivos usados se mencionan la infusiĂłn y el cocimiento, pero no manifiestan un criterio definido sobre su valor terapĂ©utico ni sobre la concentraciĂłn de los mismos.Tesis digitalizada en SEDICI gracias a la Biblioteca Central de la Facultad de Ciencias Exactas (UNLP).Al momento de presentaciĂłn de esta tesis, la actual Facultad de Ciencias Exactas se denominaba Facultad de QuĂmica y Farmacia.Facultad de Ciencias Exacta
AplicaciĂłn para la suscripciĂłn a eventos deportivos
[ES] Hoy en dĂa el deporte forma parte de la vida cotidiana de gran parte la poblaciĂłn, tanto sea de forma individual o realizando deportes de equipo, por eso el objetivo de este trabajo es diseñar e implementar una aplicaciĂłn mĂłvil que permita a los usuarios practicar diferentes deportes (futbol, vĂłley, PĂĄdel, bĂĄsquet, etc.) aun si no disponen del nĂșmero suficiente de integrantes para conformar un equipo completo. Concretamente se diseñarĂĄ una aplicaciĂłn que permitirĂĄ a los usuarios la creaciĂłn de diferentes eventos deportivos para que otros usuarios se puedan unir y poder practicar el deporte en cuestiĂłn.
Para el desarrollo de la aplicaciĂłn mĂłvil se utilizarĂĄ Java como lenguaje de programaciĂłn y para el resto de las partes de nuestro sistema (servidor, base de datos, etc.) se utilizarĂĄ tecnologĂa Firebase porque nos proporciona una amplia gama de servicios y herramientas que nos ayudarĂĄn y facilitarĂĄn el trabajo a la hora de desarrollar y ademĂĄs porque es una tecnologĂa que estĂĄ siendo muy utilizada en el mundo laboral hoy en dĂa[EN] Nowadays sport is part of the daily life of a large part of the society, either individually or in team sports, so the objective of this project is to design and implement a phone application that allows users to practice different sports (soccer, volleyball, paddle, basketball, etc.) even if they do not have enough members to form a complete team. Specifically, this application will be designed that will allow users to create different sporting events so that other users can join and be able to practice the sport in question.
The development of the mobile application will be based on Java as a programming language and for the rest of the parts of our system (server, database, etc.) we wilñl use Firebase becaus, on the one hand, it provides us a wide range of development services and tools, and on the other hand, it is a technology that is being widely used in the world of work today.Yerle Ballara, CM. (2020). Aplicación para la suscripción a eventos deportivos. http://hdl.handle.net/10251/151019TFG
Therapeutic targets in rheumatoid arthritis: the interleukin-6 receptor
RA is a chronic, debilitating disease in which articular inflammation and joint destruction are accompanied by systemic manifestations including anaemia, fatigue and osteoporosis. IL-6 is expressed abundantly in the SF of RA patients and is thought to mediate many of the local and systemic effects of this disease. Unlike a number of other cytokines, IL-6 can activate cells through both membrane-bound (IL-6R) and soluble receptors (sIL-6R), thus widening the number of cell types responsive to this cytokine. Indeed, trans-signalling, where IL-6 binds to the sIL-6R, homodimerizes with glycoprotein 130 subunits and induces signal transduction, has been found to play a key role in acute and chronic inflammation. Elevated levels of IL-6 and sIL-6R in the SF of RA patients can increase the risk of joint destruction and, at the joint level, IL-6/sIL-6R can stimulate pannus development through increased VEGF expression and increase bone resorption as a result of osteoclastogenesis. Systemic effects of IL-6, albeit through conventional or trans-signalling, include regulation of acute-phase protein synthesis, as well as hepcidin production and stimulation of the hypothalamo-pituitary-adrenal axis, the latter two actions potentially leading to anaemia and fatigue, respectively. This review aims to provide an insight into the biological effects of IL-6 in RA, examining how IL-6 can induce the articular and systemic effects of this disease
Franchises lost and gained: post-coloniality and the development of womenâs rights in Canada
The Canadian constitution is to some extent characterised by its focus on equality, and in particular gender equality. This development of womenâs rights in Canada and the greater engagement of women as political actors is often presented as a steady linear process, moving forwards from post-enlightenment modernity. This article seeks to disturb this âdiscourse of the continuous,â by using an analysis of the pre-confederation history of suffrage in Canada to both refute a simplistic linear view of womenâs rights development and to argue for recognition of the Indigenous contribution to the history of womenâs rights in Canada.
The gain of franchise and suffrage movements in Canada in the late nineteenth and early twentieth century are, rightly, the focus of considerable study (Pauker 2015), This article takes an alternative perspective. Instead, it examines the exercise of earlier franchises in pre-confederation Canada. In particular it analyses why franchise was exercised more widely in Lower Canada and relates this to the context of the removal of franchises from women prior to confederation
Crosslink Density Changes during the Hydrolysis of Tridimensional Polyesters
The hydrolysis of almost ideal networks based on macrodiols of average molar mass about 2 kg mol 1, with LŒ18 ester groups per chain is studied. Tensile testing is used to evaluate the crosslink density through the statistical theory of rubber elasticity at two temperatures and three values of relative humidity. A kinetic model for ester consumption including an autocatalysis term is proposed and combined with two original approaches for modeling the crosslink density changes. This allows kinetic parameters of hydrolysis to be determined, and very good predictions are obtained for the variations of crosslink density (or elastic modulus) in the three aging conditions considered. The initial curvature of elastic modulus versus time is predicted positive for weak autocatalysis and negative for strong autocatalysis. The obtained conversion ratio at degelation is found to decrease sharply with the number of esters per elastically active chaincontrat de recherche SAFRAN - ART
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