Capturing planar shapes by approximating their outlines

AbstractA non-deterministic evolutionary approach for approximating the outlines of planar shapes has been developed. Non-uniform Rational B-splines (NURBS) have been utilized as an underlying approximation curve scheme. Simulated Annealing heuristic is used as an evolutionary methodology. In addition to independent studies of the optimization of weight and knot parameters of the NURBS, a separate scheme has also been developed for the optimization of weights and knots simultaneously. The optimized NURBS models have been fitted over the contour data of the planar shapes for the ultimate and automatic output. The output results are visually pleasing with respect to the threshold provided by the user. A web-based system has also been developed for the effective and worldwide utilization. The objective of this system is to provide the facility to visualize the output to the whole world through internet by providing the freedom to the user for various desired input parameters setting in the algorithm designed

Laser sensor for detection of SF6 leaks in high powerinsulated switchgear systems

A novel photoacoustic spectrometer (PA) has been developed for in-situ detection of SF6 leaks in low concentrations. The developed system is equipped with a sound alarm system and has been tested in the laboratory for very minute SF6 leaks. This newly developed SF6 detection device utilizes a high quality factor resonant photoacoustic cell and continuous wave (CW) line tunable CO2 laser at 10.55 m wavelength. Whenever SF6 is detected an acoustic signal is generated and no signal appears from ambient air if there is no leakage of SF6. An electret microphone is used for the detection of these acoustic signals. The system is capable of detecting leaks of the order of 3.5 ppbv (parts per billion by volume) concentration. This device has been proved to have significant applications to industrial organizations that have electric power gas insulated systems (GIS). It could be also applied for other applications such as monitoring of environmental pollutants with minimal adjustment

Laser sensor for detection of SF6 leaks in high powerinsulated switchgear systems

A novel photoacoustic spectrometer (PA) has been developed for in-situ detection of SF6 leaks in low concentrations. The developed system is equipped with a sound alarm system and has been tested in the laboratory for very minute SF6 leaks. This newly developed SF6 detection device utilizes a high quality factor resonant photoacoustic cell and continuous wave (CW) line tunable CO2 laser at 10.55 m wavelength. Whenever SF6 is detected an acoustic signal is generated and no signal appears from ambient air if there is no leakage of SF6. An electret microphone is used for the detection of these acoustic signals. The system is capable of detecting leaks of the order of 3.5 ppbv (parts per billion by volume) concentration. This device has been proved to have significant applications to industrial organizations that have electric power gas insulated systems (GIS). It could be also applied for other applications such as monitoring of environmental pollutants with minimal adjustment

Conceptual design and performance evaluation of a hybrid concentrating photovoltaic system in preparation for energy

Concentrating sunlight and focussing it on smaller sized solar cells increases the device's power output per unit active area. However, this process tends to increase the solar cell temperature considerably and has the potential to compromise system reliability. Adding a heat exchanger system to regulate this temperature rise, can improve the electrical performance whilst simultaneously providing an additional source of low temperature heat. In this study the performance of a low concentrator photovoltaic system with thermal (LCPV/T) extraction was conceptualised and evaluated in depth. An experimental analysis was performed using a first-generation prototype consisting of 5 units of Cross Compound Parabolic Concentrators (CCPC) connected to a heat extraction unit. A bespoke rotating table was used as experimental apparatus to effectively evaluate the optical performance of the system, as a function of its angular positions to replicate the motion of actual sun. Key design performance parameters for the LCPV/T collector are presented and discussed. This work also provides a useful technique to effectively calculate system performance, as a function of the orientation-dependant electrical characterisation parameters data. Finally, a Computational Fluid Dynamics (CFD) model was also applied to investigate the efficacy of the heat exchanger and hence estimate the overall co-generation benefit of using such optimisation techniques on realistic CPV systems. It was highlighted through these simulations that the water flow rate had the potential to be a critical power-generation optimisation criterion for LCPV-T systems. The maximum power output at normal incidence with concentrators and no water flow was found to be 78.4 mW. The system was found to perform with an average electrical efficiency ranging between 10 and 16% when evaluated at five different geographic locations. Experimental analysis of the data obtained showed an increase in power of 141% (power ratio 2.41) compared to the analogous non-concentrating counterpart. For example, in the case of London which receives an annual solar radiation of 1300 kWh/m2 the system is expected to generate 210 kWh/m2. This may reduce further to include losses due to temperature, reflectance/glazing losses, and electrical losses in cabling and inverter by up to 36% leading to an annual power output of 134 kWh/m2 of module

Cigarette pack messages about toxic chemicals: A randomised clinical trial

Background The USA can require tobacco companies to disclose information about harmful and potentially harmful chemicals in cigarette smoke, but the impact of these messages is uncertain. We sought to assess the effect of placing messages about toxic chemicals on smokers' cigarette packs. Methods Participants were 719 adult cigarette smokers from California, USA, recruited from September 2016 through March 2017. We randomly assigned smokers to receive either factual messages about chemicals in cigarette smoke and their health harms (intervention) or messages about not littering cigarette butts (control) on the side of their cigarette packs for 3 weeks. The primary trial outcome was intention to quit smoking. Results In intent-to-treat analyses, smokers whose packs had chemical messages did not have higher intentions to quit smoking at the end of the trial than those whose packs had control messages (P=0.56). Compared with control messages, chemical messages led to higher awareness of the chemicals (28% vs 15%, P<0.001) and health harms (60% vs 52%, P=0.02) featured in the messages. In addition, chemical messages led to greater negative affect, thinking about the chemicals in cigarettes and the harms of smoking, conversations about the messages and forgoing a cigarette (all P<0.05). Discussion Chemical messages on cigarette packs did not lead to higher intentions to quit among smokers in our trial. However, chemical messages informed smokers of chemicals in cigarettes and harms of smoking, which directly supports their implementation and would be critical to defending the messages against cigarette company legal challenges. Trial registration number NCT02785484

Public Understanding of Cigarette Smoke Chemicals: Longitudinal Study of US Adults and Adolescents

Introduction: The US Food and Drug Administration has increased communication efforts that aim to raise public awareness of the harmful constituents (ie, chemicals) in cigarette smoke. We sought to investigate whether the public's awareness of these chemicals has increased in light of such efforts. Methods: Participants were national probability samples of 11 322 US adults and adolescents recruited in 2014-2015 (wave 1) and 2016-2017 (wave 2). Cross-sectional telephone surveys assessed awareness of 24 cigarette smoke chemicals at both timepoints. Results: The proportion of US adults aware of cigarette smoke chemicals did not differ between waves 1 and 2 (25% and 26%, p =. 19). In contrast, awareness of chemicals among adolescents fell from 28% to 22% (p <. 001), mostly due to lower awareness of carbon monoxide, arsenic, benzene, and four other chemicals. Belief that most of the harmful chemicals in cigarette smoke come from burning the cigarette also fell from waves 1 to 2 (adults: 31% vs. 26%; adolescents: 47% vs. 41%, both ps <. 05). Participants were more likely to be aware of cigarette smoke chemicals if they had been exposed to anti-smoking campaign advertisements (p <. 05) or had previously sought chemical information (p <. 05). Cigarette smoke chemical awareness did not differ between smokers and nonsmokers. Conclusion: Awareness of cigarette smoke chemicals remains low and unchanged among adults and decreased somewhat among adolescents. The association of chemical awareness with information exposure via campaigns and information seeking behavior is promising. More concerted communication efforts may be needed to increase public awareness of cigarette smoke chemicals, which could potentially discourage smoking. Implications: Awareness of the toxic chemicals in cigarette smoke may contribute to quitting. The US Food and Drug Administration is making efforts to increase public awareness of these chemicals. Two national surveys (2014-2017) found that chemical awareness was low among adults and adolescents. Although awareness did not change among adults, awareness among adolescents dropped over time. In addition, exposure to anti-smoking campaigns and chemical information seeking behavior were associated with higher awareness of chemicals in cigarette smoke. Campaigns and other efforts may be needed to increase awareness of cigarette smoke chemicals

Tracking development assistance for health and for COVID-19 : a review of development assistance, government, out-of-pocket, and other private spending on health for 204 countries and territories, 1990-2050

Background The rapid spread of COVID-19 renewed the focus on how health systems across the globe are financed, especially during public health emergencies. Development assistance is an important source of health financing in many low-income countries, yet little is known about how much of this funding was disbursed for COVID-19. We aimed to put development assistance for health for COVID-19 in the context of broader trends in global health financing, and to estimate total health spending from 1995 to 2050 and development assistance for COVID-19 in 2020. Methods We estimated domestic health spending and development assistance for health to generate total health-sector spending estimates for 204 countries and territories. We leveraged data from the WHO Global Health Expenditure Database to produce estimates of domestic health spending. To generate estimates for development assistance for health, we relied on project-level disbursement data from the major international development agencies' online databases and annual financial statements and reports for information on income sources. To adjust our estimates for 2020 to include disbursements related to COVID-19, we extracted project data on commitments and disbursements from a broader set of databases (because not all of the data sources used to estimate the historical series extend to 2020), including the UN Office of Humanitarian Assistance Financial Tracking Service and the International Aid Transparency Initiative. We reported all the historic and future spending estimates in inflation-adjusted 2020 US$, 2020 US$ per capita, purchasing-power parity-adjusted US$per capita, and as a proportion of gross domestic product. We used various models to generate future health spending to 2050. Findings In 2019, health spending globally reached$8. 8 trillion (95% uncertainty interval [UI] 8.7-8.8) or $1132 (1119-1143) per person. Spending on health varied within and across income groups and geographical regions. Of this total,$40.4 billion (0.5%, 95% UI 0.5-0.5) was development assistance for health provided to low-income and middle-income countries, which made up 24.6% (UI 24.0-25.1) of total spending in low-income countries. We estimate that $54.8 billion in development assistance for health was disbursed in 2020. Of this,$13.7 billion was targeted toward the COVID-19 health response. $12.3 billion was newly committed and$1.4 billion was repurposed from existing health projects. $3.1 billion (22.4$2.4 billion (17.9%) was for supply chain and logistics. Only $714.4 million (7.7$1519 (1448-1591) per person in 2050, although spending across countries is expected to remain varied. Interpretation Global health spending is expected to continue to grow, but remain unequally distributed between countries. We estimate that development organisations substantially increased the amount of development assistance for health provided in 2020. Continued efforts are needed to raise sufficient resources to mitigate the pandemic for the most vulnerable, and to help curtail the pandemic for all. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4 (62.3 (55.1�70.8) million) to 6.4 (58.3 (47.6�70.7) million), but is predicted to remain above the World Health Organization�s Global Nutrition Target of <5 in over half of LMICs by 2025. Prevalence of overweight increased from 5.2 (30 (22.8�38.5) million) in 2000 to 6.0 (55.5 (44.8�67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic. © 2020, The Author(s)