Oral health status and associated lifestyle behaviors in a sample of Iranian adults : an exploratory household survey

Background Poor oral hygiene can lead to serious diseases, such as periodontitis, tooth decay, pain and discomfort in teeth or gums, infections, and loss of teeth. In Iran, adults aged 50 y and older are a high-risk group for oral health problems, and this age group will grow in the coming decades. Despite increasing attention on healthy aging, there is relatively less emphasis on oral hygiene and health-related problems. The present study investigated the oral health status of Iranian adults using the oral health self-assessment questionnaire (OHQ) developed by the World Health Organization (WHO). Methods A population-based household survey of a sample of adults aged 18-65 y was conducted. In this study, the participants were recruited between May and October 2016 in Tabriz, Iran, and the study population was sampled using a multi-stage cluster sampling design. The WHO's OHQ for adults was used for measuring oral health status and oral hygiene behavior. Results In total, 2310 respondents completed the survey. The mean age (SD) of the participants was 41.6(23.4) y. Males accounted for 48.8% of the participants. Of the 2310 respondents,187 (8.1%) individuals were edentulous, 152(20.7%) of whom were aged 51-65 y. Furthermore, 72.3% of those aged 51-65 y were dentate, and 50% of adults aged 51-65 y said they had 20 or more teeth. About one-third of the participants reported that they did not brush their teeth daily (23% of those aged 18-35 y,35.9% of those aged 36-50 y, and 44.6% for those aged 51-65 y). In the sample, 39.4% of individuals aged 18-35 y,34.1% of individuals aged 36-50 y, and 26.6% of individuals aged 51-65 y had visited a dentist less than 6 month ago. One-third of the participants consumed sweets and sugary drinks daily. Conclusions Although the majority of Iranian adults considered their oral health status good, only a small percentage of the sample visited their dentist regularly. Furthermore, visits to the dentist declined in accordance with increasing age, a time when the incidence of oral health problems may increase. Poor oral health may increase the risk of adverse health outcomes, particularly among the aging population

Pattern and Visual Prognostic Factors of Behcet’s Uveitis in Northwest Iran

Purpose: To investigate the pattern of ocular involvement in Behcet’s disease (BD) with predictors of patients’ final state of vision. Methods: This historical cohort encompassed the clinical records of 200 patients diagnosed according to the International Criteria for BD (ICBD), over a period of 17 years between 2004 and 2021. Results: The prevalence of Behcet’s uveitis (BU) was more common in females and patients in the fourth decade of life. Ninety-five patients (47.5%) had evidence of ocular involvement in the initial ophthalmologic evaluation, and 171 patients (85.5%) manifested evidence of BU during the follow-up visits of which bilateral non-granulomatous panuveitis was the most common anatomical pattern of involvement (32.9%) followed by posterior (27.6%), anterior (26.5%), and intermediate (13.8%) uveitis. The prevalent accompanying signs were oral aphthous (67%), skin lesions (29%), and genital ulcers (19.5%). Cystoid macular edema (CME) was the most frequent ocular complication (62%), followed by cataract (57.5%) and epiretinal membranes (ERM) (36.5%). Univariate analysis showed the following determinants: male gender, younger age at onset, panuveitis, posterior uveitis, retinal vasculitis, and longer duration of uveitis as poorer visual prognostic factors of the disease. Multivariate analysis demonstrated a higher chance of poor visual prognosis of BD in patients with panuveitis, posterior uveitis, retinal vasculitis, and longer duration of uveitis. Conclusion: This cohort study demonstrated an overview on epidemiological patterns of BU along with the visual prognostic factors in Iranian patients

Optical coherence tomography angiography in intermediate uveitis-related cystoid macular edema

Background: Cystoid macular edema (CME) is the leading cause of permanent visual impairment in patients with uveitis, particularly in patients with intermediate uveitis (IU). This study was aimed at comparing the changes in the macular microvasculature in patients with IU with uveitic non-responsive CME and without macular edema. Methods: In this case-control study, 55 eyes of patients with IU were assessed for macular microvascular structures, including vascular density, foveal avascular zone (FAZ) measurement, and vascular morphological changes, using spectral-domain optical coherence tomography angiography (OCT-A) with the AngioVue OCT-A system. We divided patients into the following two groups: the case group, including 30 eyes with IU-related non-responsive CME, and the control group, including 25 eyes with IU without macular edema. Results: Participants in the case and control groups had comparable age (P = 0.753) and sex (P = 0.124) distributions. Superficial capillary plexus vessel density in the case group was significantly decreased in the whole image (P = 0.027) and the parafoveal area (P  = 0.001) compared to the control group. However, there were no statistically significant differences between the two groups in terms of foveal superficial vessel density, deep capillary plexus vessel density, FAZ area, FAZ perimeter, FAZ acircularity index, or foveal vessel density in a 300-µm-wide annulus around the FAZ (all P > 0.05). Vascular morphological changes, such as the capillary tuft, telangiectatic vessels, or micro-aneurism, were not different in the overview images of the OCT-A printout between the two groups. Conclusions: The mean superficial capillary plexus vessel density was lower in eyes with IU-related nonresponsive CME than in those without macular edema. We observed more cystoid spaces in SCP than in DCP. Microcystic changes in the inner retina and ischemia may be the underlying cause in eyes with nonresponsive CME. Future prospective longitudinal studies with healthy, matched controls are warranted to confirm our findings

Comparison of Azithromycin and Pyrimethamine/Sulfadiazine Treatment in Ocular Toxoplasmosis in North West of Iran

Objective: Ocular toxoplasmosis (OT), characterized by necrotizing retinochoroiditis, scar formation and decreased vision, is recognized as the most prevalent cause of posterior uveitis in Iran. Although pyrimethamine/sulfadiazine combination remains the standard treatment particularly for patients with sight-threatening lesions, intolerance, inaccessibility and adverse drug reactions to this regimen have imposed us to seek for alternative treatments. Materials and Methods: In this prospective randomized control clinical trial study, 72 patients with active, non-vision threatening toxoplasmic chorioretinitis were randomly divided into 2 treatment regimen: 36 patients treated with standard protocol with pyrimethamine/sulfadiazine, and 36 patients received azithromycin for 6 weeks. All patients were followed up for 24 months. The clinical outcomes measured before and after intervention were, time to disease inactivity (lesion borders sharpening and scarring), changes in the size of retinochoroidal lesion, rate of recurrence, adverse drug reactions and visual acuity (VA). Results: No significant difference was noted between the 2 groups regarding age, gender, and VA before treatment. Significant improvement was noted in VA for each group during treatment. VA increased by 0.39 logMAR units in group 1 (P = 0.00) and 0.35 logMAR units in group 2 (P = 0.00). There was no statistically significant difference between the 2 groups concerning visual improvement (P = 0.33) and reduction in retinal lesion size and activity. There were totally 22 cases who experienced recurrences during the follow up period (4 [11.1%] patients of control group and 18 [50%] of intervention group [P = 0.00]), indicating significant lower recurrence in control group. Treatment tolerance was significantly better for the azithromycin group due to lower adverse drug reactions (P = 0.00). Conclusion: Azithromycin at a dose of 250 mg/d was shown to be effective for the treatment of active, non-vision threatening toxoplasmic retinochoroiditis similar to classic treatment with Pyrimethamine/Sulfadiazine regimen. However, recurrences and adverse drug reactions seem to differ significantly which notes the need for further studies and also vigilant selection of treatment protocols

Clinical Course of Uveitis in Children in a Tertiary Ophthalmology Center in Northwest Iran

Objective: In the present research, the clinical course of pediatric uveitis was studied by examining the demographic characteristics of afflicted children, the results of clinical examinations, and uveitis complications. Materials and Methods: The present research was a retrospective study in which the medical records of 243 children who had been visited and diagnosed as uveitis in the uveitis clinic of Nikookari Eye hospital of Tabriz in 2003-2015, were reviewed. The data were statistically analyzed by descriptive statistics and mean comparison tests in IBM-SPSS 23 and the significance level of P<0.05. Results:According to the results, 73 (30%), 146 (60.1%), 12 (4.9%), and 12 (4.9%) eyes diagnosed with uveitis had anterior, intermediate, posterior, and panuveitis type, respectively. In addition, 73 cases of uveitis (30%) were acute and 170 cases (70%) were chronic. Based on the LogMAR chart, the mean visual acuity before and after treatment was 0.39 and 0.15 for the right eye and 0.4 and 0.09 for the left eye, which suggests a significant difference. The most common complications observed in this study were macular edema (32.5%) and cataract (22.6%). Conclusion: This study indicates that intermediate uveitis is the most common type of pediatric uveitis, while anterior uveitis is the second. Posterior and panuveitis are less common in our study. The prevalence of chronic uveitis is significantly high in pediatric group which could justify the higher rate of complications in this age group

The influence of men’s masculine gender-role attitude and behaviour on sexual relationships and reproductive health in Malaysia: A cross-sectional study

Background: This article is an extension of previous research on masculinity and sexual and reproductive health using a newly developed local masculinity scale, KANITA Masculinity Scale, to study men’s masculine gender-role attitude and behavior in Malaysia. Objective: To explore how Malaysian men’s masculine gender-role attitude and behavior influence sexual relationships and reproductive health. Materials and Methods: This cross-sectional study used the localized genderequitable men scale to measure the attitude of Malaysian men toward sexual relationships and reproductive health. A questionnaire survey was administered to a sample of 168 men of ages 20–64 yr, in Malaysia. Data were analyzed using SmartPLS version 3.2.6. Results: The findings of the study showed that men’s traditional behavior and controlling nature are positively associated with the inequality in sexual relationships (p &lt; 0.05, t = 1.838; and p &lt; 0.05, t = 3.750, respectively) and reproductive health (p &lt; 0.05, t = 2.196; and p &lt; 0.05, t = 4.133, respectively). In other words, men who offer stronger endorsement of traditional behavior and control over women report more negative condom attitude and greater priority of men’s desire in sexual relationships. In contrast, there was no significant relationship between men’s response to family and feminine roles in men with sexual relationships and reproductive health. Conclusion: Our findings highlight the importance of considering traditional masculinity ideology when considering the role of men in sexual relationships and reproductive health. Our findings suggest gender transformative policies and programs seeking to inspire men for more gender-equitable relationships with their partners. Key words: Attitudes, Masculinity, Gender-role, Sexual health, Reproductive health, Malaysia

A Multiport Isolated Resonant LLC Converter for Grid-Tied Renewable Energy Powered Bidirectional EV Charger

This paper proposes an integrated bidirectional multiport DC-DC converter for battery charging of plug-in electric vehicles, which is able to integrate the photovoltaic (PV) system, traction batteries, and the AC grid. The presented converter is more reliable than the conventional topologies because both PV panels and the grid can simultaneously or separately deliver power to the high voltage batteries. In addition, the topology is bidirectional can transfer power from batteries to the AC grid by employing half-bridge CLLC converter with fewer switches. Moreover, a unified controller along with optimum maximum power point tracking (MPPT) algorithm is utilized for control of the converter. The converter topology, control system, and operating scenarios are analyzed by using state space modeling. To evaluate the whole system performance, MATLAB/Simulink software is used to test the converter’s operation during different conditions. The simulation results depict that the proposed converter is not only able to control the batteries charge and discharge according to the state of the charge, but also maintain the DC-link voltage of the grid side to be in constant level

Electrochemical alcohols oxidation mediated by N-hydroxyphthalimide on nickel foam surface

Alcohol to aldehyde conversion is a critical reaction in the industry. Herein, a new electrochemical method is introduced that converts 1 mmol of alcohols to aldehydes and ketones in the presence of N-hydroxyphthalimide (NHPI, 20 mol%) as a mediator; this conversion is achieved after 8.5 h at room temperature using a piece of Ni foam (1.0 cm2) and without adding an extra-base or a need for high temperature. Using this method, 10 mmol (1.08 g) of benzyl alcohol was also successfully oxidized to benzaldehyde (91%) without any by-products. This method was also used to oxidize other alcohols with high yield and selectivity. In the absence of a mediator, the surface of the nickel foam provided oxidation products at the lower yield. After the reaction was complete, nickel foam (anode) was characterized by a combination of scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), X-ray absorption spectroscopy (XAS), X-ray photoelectron spectroscopy (XPS), and spectroelectrochemistry, which pointed to the formation of nickel oxide on the surface of the electrode. On the other hand, using other electrodes such as Pt, Cu, Fe, and graphite resulted in a low yield for the alcohol to aldehyde conversion

The effect of saffron supplementation on blood pressure in adults:A systematic review and dose-response meta-analysis of randomized controlled trials

Background: The favorable influences of saffron supplementation on metabolic diseases have previously been shown. We aimed to assess the effects of saffron supplementation on blood pressure in adults. Methods: A systematic search was performed in Scopus, Embase, and the Cochrane library databases to find randomized controlled trials (RCTs) related to the effect of saffron supplementation on blood pressure in adults up to March 2021. The primary search yielded 182 publications, of which eight RCTs were eligible. Results: Our results showed that saffron supplementation resulted in a significant decrease in systolic blood pressure (weighted mean difference (WMD): −0.65 mmHg; 95% CI: −1.12 to −0.18, p = 0.006) and diastolic blood pressure (DBP) (WMD: −1.23 mmHg; 95% CI: −1.64 to −0.81, p p-nonlinearity = 0.008). Conclusions: Saffron supplementation may significantly improve both systolic and diastolic blood pressure in adults. It should be noted that the hypotensive effects of saffron supplementation were small and may not reach clinical importance

A systematic review and meta-analysis of pregnancy and COVID-19: Signs and symptoms, laboratory tests, and perinatal outcomes

Background: Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 appeared in December 2019 in Wuhan, China. Objective: To investigate the clinical manifestations including signs and symptoms, laboratory results, and perinatal outcomes in pregnant women with COVID-19. Materials and Methods: Scholarly databases such as PubMed via LitCovid hub, Embase, Scopus, Web of sciences, and Google scholar were searched on April 7, 2020. Meta-analysis was performed via comprehensive meta-analysis software using the Mantel-Haenszel method. The event rate with 95% CI was calculated for each variable. Results: Ten studies were selected. The pooled prevalence for fever, post-partum fever, cough, myalgia, fatigue, dyspnea, sore throat, and diarrhea were 66.8%, 37.1%, 35%, 24.6 %, 14.9%, 14.6%, 11.5%, and 7.6%, respectively. Laboratory test results were 49.8% for lymphopenia, 47.7% for leukocytosis, 83.7% for elevated neutrophil ratio, 57% for elevated C-reactive protein, and 71.4% for decreased lymphocyte ratio. The rate of cesarean section for delivery in all cases was 84%. Of the newborns of the corona positive mothers, only one had a positive test result. Also, there was only one death due to a decreased lymphocyte ratio. Conclusion: Fever was the most common sign and symptom in pregnant women with COVID-19. Among the laboratory tests, the highest amount was related to elevated neutrophil ratio. It seems that due to the differences between pregnant women and the general population, special measures should be considered to treat these patients. Key words: COVID-19, Pregnancy, Diagnosis, Signs and symptoms, Meta-analysis