80 research outputs found
Fitting the integrated Spectral Energy Distributions of Galaxies
Fitting the spectral energy distributions (SEDs) of galaxies is an almost
universally used technique that has matured significantly in the last decade.
Model predictions and fitting procedures have improved significantly over this
time, attempting to keep up with the vastly increased volume and quality of
available data. We review here the field of SED fitting, describing the
modelling of ultraviolet to infrared galaxy SEDs, the creation of
multiwavelength data sets, and the methods used to fit model SEDs to observed
galaxy data sets. We touch upon the achievements and challenges in the major
ingredients of SED fitting, with a special emphasis on describing the interplay
between the quality of the available data, the quality of the available models,
and the best fitting technique to use in order to obtain a realistic
measurement as well as realistic uncertainties. We conclude that SED fitting
can be used effectively to derive a range of physical properties of galaxies,
such as redshift, stellar masses, star formation rates, dust masses, and
metallicities, with care taken not to over-interpret the available data. Yet
there still exist many issues such as estimating the age of the oldest stars in
a galaxy, finer details ofdust properties and dust-star geometry, and the
influences of poorly understood, luminous stellar types and phases. The
challenge for the coming years will be to improve both the models and the
observational data sets to resolve these uncertainties. The present review will
be made available on an interactive, moderated web page (sedfitting.org), where
the community can access and change the text. The intention is to expand the
text and keep it up to date over the coming years.Comment: 54 pages, 26 figures, Accepted for publication in Astrophysics &
Space Scienc
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Leptin is an adipocyte-secreted hormone, the circulating levels of which correlate closely with overall adiposity. Although rare mutations in the leptin (LEP) gene are well known to cause leptin deficiency and severe obesity, no common loci regulating circulating leptin levels have been uncovered. Therefore, we performed a genome-wide association study (GWAS) of circulating leptin levels from 32,161 individuals and followed up loci reaching P<10(-6) in 19,979 additional individuals. We identify five loci robustly associated (P<5 × 10(-8)) with leptin levels in/near LEP, SLC32A1, GCKR, CCNL1 and FTO. Although the association of the FTO obesity locus with leptin levels is abolished by adjustment for BMI, associations of the four other loci are independent of adiposity. The GCKR locus was found associated with multiple metabolic traits in previous GWAS and the CCNL1 locus with birth weight. Knockdown experiments in mouse adipose tissue explants show convincing evidence for adipogenin, a regulator of adipocyte differentiation, as the novel causal gene in the SLC32A1 locus influencing leptin levels. Our findings provide novel insights into the regulation of leptin production by adipose tissue and open new avenues for examining the influence of variation in leptin levels on adiposity and metabolic health
Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci.
Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, but the nature of the suggestive comorbidity is still unknown. We used a novel genetic pleiotropy-informed conditional False Discovery Rate (FDR) method to identify single nucleotide polymorphisms (SNPs) associated with BMD by leveraging cardiovascular disease (CVD) associated disorders and metabolic traits. By conditioning on SNPs associated with the CVD-related phenotypes, type 1 diabetes, type 2 diabetes, systolic blood pressure, diastolic blood pressure, high density lipoprotein, low density lipoprotein, triglycerides and waist hip ratio, we identified 65 novel independent BMD loci (26 with femoral neck BMD and 47 with lumbar spine BMD) at conditional FDR < 0.01. Many of the loci were confirmed in genetic expression studies. Genes validated at the mRNA levels were characteristic for the osteoblast/osteocyte lineage, Wnt signaling pathway and bone metabolism. The results provide new insight into genetic mechanisms of variability in BMD, and a better understanding of the genetic underpinnings of clinical comorbidity
The VMC survey II : A multi-wavelength study of LMC planetary nebulae and their mimics
Original article can be found at : http://www.aanda.org/ Copyright The European Southern ObservatoryThe VISTA Magellanic Cloud (VMC) survey is assembling a deep, multi-epoch atlas of Y JKs photometry across the Magellanic Clouds. Prior to the VMC survey only the brightest Magellanic Cloud PNe (MCPNe) were accessible at near-infrared (NIR) wavelengths. It is now possible for the first time to assemble the NIR properties of MCPNe and to identify contaminating non-PNe mimics which are best revealed at NIR wavelengths (e.g. HII regions and symbiotic stars). To maintain the unique scientific niche that MCPNe occupy these contaminants must be removed. Here we conduct a VMC-led, multi-wavelength study of 102 objects previously classified as PNe that are located within the first six VMC tiles observed. We present images, photometry, lightcurves, diagnostic colour-colour diagrams and spectral energy distributions used to analyse the entire sample. At least five PNe have newly resolved nebula morphologies, a task previously only possible with the HST. A total 45/67 (67%) of Reid & Parker (RP) catalogued objects were reclassified as non-PNe, most of which were located in the vicinity of 30 Doradus. This sample included 16 field stars, 5 emission line stars, 19 HII regions, 4 symbiotic star candidates and 1 young stellar object. We discuss possible selection effects responsible for their inclusion in the RP catalogue and the implications for binary central star surveys targeting LMC PNe. A total of five new LMC symbiotic star candidates identified, compared to eight previously known, underlines the important role the VMC survey will have in advancing Magellanic symbiotic star studies.Peer reviewe
Digestibility of nine hybrid sorghum grains fed to finishing steers winter 1971-72
Nine hybrid sorghum grains representing hetero-yellow, all-waxy, white, part-waxy, and white endosperm were fed to finishing steers to determine digestibility. Hybrids were all planted on the same irrigated bottom field and harvested and stored separately till fed. The sorghum grains were dry-rolled and incorporated into 90% concentrate rations. Digestibilities were determined using chromic oxide
Part III: Digestibility of eight hybrid sorghum grains and three hybrid corns
Apparent coefficient of digestion (COD) was determined for eight hybrid sorghum grains and three hybrid corns named in Part I
Top spoilage losses in horizontal silos in western Kansas
The top 3 feet from 30 horizontal silos was
sampled at three depths to determine top
spoilage losses, using ash content as an internal
marker. When compared to face samples, corn
and forage sorghum silages exhibited similar
additional organic matter (OM) losses in the top
18 inches. In the top 18 inches, covering silage
reduced spoilage losses of OM from 41 to 27
percentage units compared to uncovered
counterparts. Covering corn silage reduced
spoilage losses of OM from 49 to 31 and 9 to 1
percentage units in the top and second 18
inches, respectively. Similar reductions in OM
losses from covering were observed in the
forage sorghum silages. Although spoilage
losses observed in covered silages appear high,
covering silage stored in horizontal silos greatly
reduced the estimated storage losses in the top 3
feet
- …