40 research outputs found
Auditory Cortex Basal Activity Modulates Cochlear Responses in Chinchillas
- Author
- AB Elgoyhen
- AB Elgoyhen
- AE Luebke
- AJ Fenoy
- Alex León
- AM Thompson
- B Coomber
- BJ Hefti
- BR Schofield
- Carlos M. Hamamé
- CC Hunt
- CG Le Prell
- CG Le Prell
- D Elgueda
- D Lima da Costa
- Diego Elgueda
- DK Ryugo
- EJ Tehovnik
- F Luo
- FM Antunes
- J de Boer
- J Fex
- J Ruel
- J Zhang
- JA Groff
- JA Winer
- JJ Guinan Jr
- JR Doucet
- Jun Yan
- KN Darrow
- KT Nakamoto
- L Robles
- M Contreras
- M Eybalin
- M Feliciano
- M Riga
- María A. Silva
- ML Gifford
- MS Malmierca
- N Harel
- N Harel
- N Suga
- ND Engineer
- P Froehlich
- Paul H. Delano
- PH Delano
- R Galambos
- R Velluti
- RF Huffman
- RK de Venecia
- RV Harrison
- S Hatzopoulos
- S Khalfa
- SF Maison
- SG Lomber
- SG Lomber
- SW Kuffler
- VM Bajo
- W Zhang
- WB Warr
- WH Mulders
- WH Mulders
- WH Mulders
- X Liu
- X Perrot
- XY Zheng
- Z Xiao
- Z Xiao
- Z Xiao
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
Background: The auditory efferent system has unique neuroanatomical pathways that connect the cerebral cortex with sensory receptor cells. Pyramidal neurons located in layers V and VI of the primary auditory cortex constitute descending projections to the thalamus, inferior colliculus, and even directly to the superior olivary complex and to the cochlear nucleus. Efferent pathways are connected to the cochlear receptor by the olivocochlear system, which innervates outer hair cells and auditory nerve fibers. The functional role of the cortico-olivocochlear efferent system remains debated. We hypothesized that auditory cortex basal activity modulates cochlear and auditory-nerve afferent responses through the efferent system. Methodology/Principal Findings: Cochlear microphonics (CM), auditory-nerve compound action potentials (CAP) and auditory cortex evoked potentials (ACEP) were recorded in twenty anesthetized chinchillas, before, during and after auditory cortex deactivation by two methods: lidocaine microinjections or cortical cooling with cryoloops. Auditory cortex deactivation induced a transient reduction in ACEP amplitudes in fifteen animals (deactivation experiments) and a permanent reduction in five chinchillas (lesion experiments). We found significant changes in the amplitude of CM in both types of experiments, being the most common effect a CM decrease found in fifteen animals. Concomitantly to CM amplitude changes, we found CAP increases in seven chinchillas and CAP reductions in thirteen animals. Although ACE
Combination of CMS searches for heavy resonances decaying to pairs of bosons or leptons
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullah WAT Wan
- Abdullin S
- Abercrombie D
- Acharya H
- Acosta D
- Acosta JG
- Adam W
- Adams MR
- Adams T
- Adan D Perez
- Adzic P
- Afanasiev S
- Agapitos A
- Aggleton R
- Agram J-L
- Aguilar-Benitez M
- Ahmad A
- Ahmad M
- Ahmad W Haj
- Ahuja S
- Akbiyik M
- Akchurin N
- Akgun B
- Albajar C
- Albergo S
- Albert A
- Albrow M
- Alcaraz Maestre J
- Aleksandrov A
- Alexander J
- Alhusseini M
- Alimena J
- Allen B
- Almond J
- Alvarez Fernandez A
- Alverson G
- Alves FL
- Alves GA
- Alyari M
- Amapane N
- Ambrogi F
- Amendola C
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- Amsler C
- Anagnostou G
- Anampa K Hurtado
- Anderson D
- Andrea J
- Andreev V
- Andreev Yu
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- Angioni GL Pinna
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- Kreczko L
- Kreis B
- Kress T
- Krintiras G
- Krofcheck D
- Krolikowski J
- Kropivnitskaya A
- Kruecker D
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- Lagarde F
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- Lelas D
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- Neutelings I
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- Obertino MM
- Obraztsov S
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- Organtini G
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- Padula Sandra S
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- Potenza R
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- Prado Da Silva WL
- Presilla M
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- Prisciandaro J
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- Rane A
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- Rappoccio S
- Raspereza A
- Rastogi A
- Rath Y
- Rathjens D
- Ratti SP
- Rauch MP
- Rauco G
- Ravera F
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- Razis PA
- Re V
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- Rebello Teles P
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- Redondo I
- Regnard S
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- Reithler H
- Rembser J
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- Rodriguez Bouza V
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- Roguljic M
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- Rohlf J
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- Rolandi G
- Romeo F
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- Ronchese P
- Roozbahani B
- Rorie J
- Rose A
- Rosenzweig D
- Roskas C
- Roskes J
- Rosowsky A
- Rossi A
- Rossi AM
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- Rossin R
- Rout PK
- Rovelli C
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- Rovere M
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- Royon C
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- Ruggles T
- Ruini D
- Ruiz del Arbol P Martinez
- Ruiz-Jimeno A
- Rumerio P
- Rusack R
- Ruspa M
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- Ryd A
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- Ryutin R
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- Safronov G
- Saggio A
- Sagir S
- Saha G
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- Sahoo DK
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- Sandeep K
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- Santanastasio F
- Santocchia A
- Santoro A
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- Sauvan JB
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- Scodellaro L
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- Segura Delgado MA
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- Seitz C
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- Sekmen S
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- Seo SH
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- Sevilla M Franco
- Sexton-Kennedy E
- Sfar H Rejeb
- Sguazzoni G
- Shah Aashaq
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- Shchelina K
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- Sheldon P
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- Shirazi SMA Ghiasi
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- Shopova M
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- Simonetto F
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- Sirois Y
- Siroli GP
- Sirunyan AM
- Skatchkov N
- Skinnari L
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- Skovpen Y
- Skuja A
- Slabospitskii S
- Smirnov I
- Smirnov V
- Smith C
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- Snow GR
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- Sola V
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- Suranyi O
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- Tiko A
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- Tiwari PC
- Tkaczyk S
- Tlisov D
- Tok UG
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- Tomalin IR
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- Toropin A
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- Tos K
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- Tran NV
- Treille D
- Trevisani N
- Triantis FA
- Tricomi A
- Triossi A
- Tripathi M
- Trocino D
- Trocsanyi ZL
- Troshin S
- Trovato M
- Tsamalaidze Z
- Tsiakkouri D
- Tsipolitis G
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- Tumasyan A
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- Tuominen E
- Tuominiemi J
- Turkcapar S
- Turkot O
- Tuuva T
- Tuve C
- Tytgat M
- Tyurin N
- Uchida K
- Ujvari B
- Ulmer KA
- Ulrich R
- Undleeb S
- Uniyal R
- Uplegger L
- Uribe Estrada C
- Usai E
- Uvarov L
- Uzunian A
- Vaandering EW
- Vagnerini A
- Vai I
- Vaitkus J
- Valencia Palomo L
- Valuev V
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- Van Parijs I
- Van Putte S
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- Vander Velde C
- Vanlaer P
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- Veckalns V
- Veelken C
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- Velkovska J
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- Venditti R
- Venturi A
- Verbeke W
- Verdini PG
- Veres GI
- Verma Ravindra Kumar
- Vermassen B
- Vernieri C
- Verweij M
- Verwilligen P
- Verzetti M
- Verzocchi M
- Veszpremi V
- Vesztergombi G
- Vidal R
- Vila I
- Vilela Pereira A
- Viliani L
- Virdee T
- Virdi AK
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- Vitulo P
- Vizan Garcia JM
- Vlasov E
- Vlimant JR
- Voevodina E
- Volkov A
- Volobouev I
- Vormwald B
- Vorobiev I
- Vorobyev A
- Voutilainen M
- Voytishin N
- Wadud MA
- Wagner SR
- Walczak M
- Walia G
- Wallny R
- Walsh R
- Waltenberger W
- Wamorkar T
- Wang B
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- Wang J
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- Wang X
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- Waqas M
- Wardle N
- Watson I
- Wayne M
- Weber HA
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- Wei H
- Weinberg M
- Wen Y
- Wertz S
- West C
- Wetzel J
- Whitbeck A
- Wichmann K
- Wickramage N
- Wiedenbeck S
- Wiederkehr SA
- Wightman A
- Williams J
- Williams T
- Willmott C
- Wimpenny S
- Winer BL
- Winterbottom D
- Wisecarver A
- Wissing C
- Wittich P
- Wittmann J
- Wittmer B
- Woehrmann C
- Wolf M
- Wolf R
- Wolfe E
- Womersley WJ
- Wong K
- Wood D
- Woodard A
- Woods N
- Wright D
- Wright J
- Wrthwein F
- Wu Z
- Wulz C-E
- Wyslouch B
- Xia F
- Xiao M
- Xiao R
- Xie S
- Xie W
- Yagil A
- Yalvac M
- Yang UK
- Yang YC
- Yates BR
- Yazgan E
- Yetkin EA
- Yohay R
- Yoo HD
- Yoo J
- Yoon I
- Yu D
- Yu GB
- Yu I
- Yu SS
- Yuan L
- Yumiceva F
- Yusli MN
- Zabi A
- Zaganidis N
- Zahid S
- Zaleski S
- Zalewski P
- Zanetti A
- Zanetti M
- Zarubin A
- Zarucki M
- Zecchinelli AG
- Zenaiev O
- Zenz SC
- Zeuner WD
- Zghiche A
- Zhang A
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- Zhang J
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- Zhokin A
- Zhu DH
- Zhu RY
- Zientek M
- Zlebcik R
- Zobec J
- Zoi I
- Zolkapli Z
- Zorbakir IS
- Zorbilmez C
- Zotto P
- Zou D
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Publication venue
- Elsevier
- Publication date
- 01/01/2019
- Field of study
CMS Collaboration: et al.A statistical combination of searches for heavy resonances decaying to pairs of bosons or leptons is presented. The data correspond to an integrated luminosity of 35.9 fb collected during 2016 by the CMS experiment at the LHC in proton-proton collisions at a center-of-mass energy of 13 TeV. The data are found to be consistent with expectations from the standard model background. Exclusion limits are set in the context of models of spin-1 heavy vector triplets and of spin-2 bulk gravitons. For mass-degenerate W′ and Z′ resonances that predominantly couple to the standard model gauge bosons, the mass exclusion at 95% confidence level of heavy vector bosons is extended to 4.5 TeV as compared to 3.8 TeV determined from the best individual channel. This excluded mass increases to 5.0 TeV if the resonances couple predominantly to fermions.Individuals have received support from the Marie-Curie program and the European Research Council and Horizon 2020 Grant, contract Nos. 675440, 752730, and 765710 (European Union); the Programa Estatal de Fomento de la Investigación Científica y Técnica de Excelencia María de Maeztu, grant MDM-2015-0509 and the Programa Severo Ochoa del Principado de Asturias
Search for the production of W^{\pm} W^{\pm} W^{\mp} events at \sqrt{s} = 13 TeV
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullah WATW
- Abdullin S
- Abercrombie D
- Acharya H
- Acosta D
- Acosta JG
- Adam W
- Adams MR
- Adams T
- Adan DP
- Adzic P
- Afanasiev S
- Agapitos A
- Agarwal G
- Aggleton R
- Agram J-L
- Aguilar-Benitez M
- Ahmad A
- Ahmad M
- Ahmad M
- Ahmad WH
- Ahuja S
- Akbiyik M
- Akchurin N
- Akgun B
- Albajar C
- Albergo S
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- Alcaraz Maestre J
- Aleksandrov A
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- Alhusseini M
- Alimena J
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- Alvarez Gonzalez B
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- Yusli MN
- Zabi A
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- Zalewski P
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- Zecchinelli AG
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- Zolkapli Z
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- Zuolo D
- Publication venue
- AMER PHYSICAL SOC
- Publication date
- 01/07/2019
- Field of study
A search for the production of events containing three W bosons predicted by the standard model is reported. The search is based on a data sample of proton-proton collisions at a center-of-mass energy of 13 TeV recorded by the CMS experiment at the CERN LHC and corresponding to a total integrated luminosity of 35.9 fb^{-1}. The search is performed in final states with three leptons (electrons or muons), or with two same-charge leptons plus two jets. The observed (expected) significance of the signal for W^{\pm} W^{\pm} W^{\mp} production is 0.60 (1.78) standard deviations, and the ratio of the measured signal yield to that expected from the standard model is 0.34_{-0.34}^{+0.62}. Limits are placed on three anomalous quartic gauge couplings and on the production of massive axionlike particles
Measurement of the Higgs boson width and evidence of its off-shell contributions to ZZ production
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdalla H
- Abdullin S
- Abercrombie D
- Abreu A
- Acharya H
- Acosta D
- Adam W
- Adamidis K
- Adams E
- Adams MR
- Adams T
- Adan DP
- Addesa FM
- Adloff C
- Adzic P
- Afanasiev S
- Agapitos A
- Agarwal G
- Aggleton R
- Agram J-L
- Aguilar-Benitez M
- Ahmad A
- Ahmad M
- Ahmad WH
- Ahmed A
- Ahuja S
- Aime C
- Akchurin N
- Akgun B
- Akpinar A
- Albergo S
- Albert A
- Albrecht S
- Albrow M
- Alcaraz Maestre J
- Alda Junior WL
- Aleksandrov A
- Alexander J
- Alhusseini M
- Alimena J
- Alison J
- Almond J
- Alpana A
- Alvarez Fernandez A
- Alvarez Gonzalez B
- Alverson G
- Alves BAFS
- Alves GA
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- Zorbilmez C
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- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
Since the discovery of the Higgs boson in 2012, detailed studies of its properties have been ongoing. Besides its mass, its width—related to its lifetime—is an important parameter. One way to determine this quantity is to measure its off-shell production, where the Higgs boson mass is far away from its nominal value, and relating it to its on-shell production, where the mass is close to the nominal value. Here we report evidence for such off-shell contributions to the production cross-section of two Z bosons with data from the CMS experiment at the CERN Large Hadron Collider. We constrain the total rate of the off-shell Higgs boson contribution beyond the Z boson pair production threshold, relative to its standard model expectation, to the interval [0.0061, 2.0] at the 95% confidence level. The scenario with no off-shell contribution is excluded at a p-value of 0.0003 (3.6 standard deviations). We measure the width of the Higgs boson as ΓH=3.2+2.4−1.7MeV, in agreement with the standard model expectation of 4.1 MeV. In addition, we set constraints on anomalous Higgs boson couplings to W and Z boson pairs
A comparison of methods for estimating forage intake, digestibility, and fecal output in red deer (Cervus elaphus)
- Publication venue
- Oxford University Press (OUP) on behalf of the American Society of Animal Science
- Publication date
- 26/02/2020
- Field of study
The objective of this experiment was to determine appropriate methods for estimating fecal output, digestibility, and intake in red deer (Cervus elaphus). Dry matter intake (DMI), digestibility, and fecal output were estimated using the dual-marker (titanium dioxide; TiO₂ and indigestible acid detergent fiber) technique, double n-alkane ratio technique (ALK) and the pulse dose (Yttrium; Y) technique to determine a suitable method to estimate DMI, fecal output, and digestibility measurements. Four male and four female deer were stratified by sex and randomly assigned either fresh-cut perennial ryegrass (Lolium perenne L.) or fresh-cut plantain (Plantago lanceolata) ad libitum in a cross-over design experiment. Actual DMI (mean ± SD: 1.5 ± 0.36 kg DM/d), digestibility (0.70 ± 0.06), and fecal output (0.45 ± 0.1 kg DM/d) were measured daily over the collection periods, and the average of each period was used for methods’ comparison. The ALK method adequately estimated digestibility and fecal output of plantain; however, overestimated digestibility (P 0.10) in DMI when diets were pooled. The overestimated DMI of the ryegrass diet led to ALK predicting greater intake when deer consumed ryegrass than plantain, which was the opposite of actual measurements. The pulse dosed Y overestimated (P < 0.05) fecal output and consequently DMI for both plantain and ryegrass, however, indicated similar trends to actual values. The dual-marker technique using TiO₂ was able to detect the statistical differences between plantain and ryegrass as the actual measurements, had moderate to strong precision (r = 0.50 to 0.66) and statistical agreement (P < 0.05) with the pooled diet data. Therefore, the dual-marker technique provided the best alternative estimation method to actual measurements of forage DMI of grazing red deer
Inverse Genetic Association Between Alcohol Preference and Severity of Alcohol Withdrawal in Two Sets of Rat Lines Selected for the Same Phenotype
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Vasoactive Intestinal Peptide and Corticotropin-Releasing Hormone Increase ??-Endorphin Release and Proopiomelanocortin Messenger RNA Levels in Primary Cultures of Hypothalamic Cells: Effects of Acute and Chronic Ethanol Treatment
- Author
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- Field of study
Nonhuman primate hybridization and the taxonomic status of Neanderthals
- Author
- Albrecht
- Brockelman
- Br�uer
- Bynum
- Cann
- Cann
- Cann
- Ciani
- d'Errico
- Devor
- Donnelly
- Duarte
- Frayer
- Froehlich
- Froehlich
- Groves
- Harpending
- Hiernaux
- Howells
- Howells
- Hublin
- Jolly
- Kidder
- Kidder
- Klein
- Krings
- Krings
- Marshall
- McHenry
- Mellars
- Norborg
- Osborne
- Ovchinnikov
- Paterson
- Pearson
- Phillips-Conroy
- Phillips-Conroy
- Prat
- Prat
- Relethford
- Relethford
- Relethford
- Relethford
- Relethford
- Relethford
- Scholz
- Simmons
- Simmons
- Simmons
- Smith
- Smith
- Straus
- Stringer
- Stringer
- Stringer
- Supriatna
- Susanne
- Tattersall
- Turb�n
- Watanabe
- Watanabe
- Watanabe
- Wilkinson
- Williams-Blangero
- Wolpoff
- Wolpoff
- Wolpoff
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2001
- Field of study
Effects of Dopamine D1 and D2 Receptor Agonists and Antagonists on Basal and Ethanol-Modulated ?-Endorphin Secretion from Hypothalamic Neurons in Primary Cultures
- Author
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Optimum simple and complex power-law channels
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study