Measurement of the B0-anti-B0-Oscillation Frequency with Inclusive Dilepton Events

The $B^0$-$\bar B^0$ oscillation frequency has been measured with a sample of 23 million \B\bar B pairs collected with the BABAR detector at the PEP-II asymmetric B Factory at SLAC. In this sample, we select events in which both B mesons decay semileptonically and use the charge of the leptons to identify the flavor of each B meson. A simultaneous fit to the decay time difference distributions for opposite- and same-sign dilepton events gives $\Delta m_d = 0.493 \pm 0.012{(stat)}\pm 0.009{(syst)}$ ps$^{-1}$.Comment: 7 pages, 1 figure, submitted to Physical Review Letter

Discovery, fine-mapping, and conditional analyses of genetic variants associated with C-reactive protein in multiethnic populations using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) study

C-reactive protein (CRP) is a circulating biomarker indicative of systemic inflammation. We aimed to evaluate genetic associations with CRP levels among non-European-ancestry populations through discovery, fine-mapping and conditional analyses. A total of 30 503 non-European-ancestry participants from 6 studies participating in the Population Architecture using Genomics and Epidemiology study had serum high-sensitivity CRP measurements and ~200 000 single nucleotide polymorphisms (SNPs) genotyped on the Metabochip. We evaluated the association between each SNP and log-transformed CRP levels using multivariate linear regression, with additive genetic models adjusted for age, sex, the first four principal components of genetic ancestry, and study-specific factors. Differential linkage disequilibrium patterns between race/ ethnicity groups were used to fine-map regions associated with CRP levels. Conditional analyses evaluated for multiple independent signals within genetic regions. One hundred and sixty-three unique variants in 12 loci in overall or race/ ethnicity-stratified Metabochip-wide scans reached a Bonferroni-corrected P-value<2.5E-7. Three loci have no (HACL1, OLFML2B) or only limited (PLA2G6) previous associations with CRP levels. Six loci had different top hits in race/ethnicityspecific versus overall analyses. Fine-mapping refined the signal in six loci, particularly in HNF1A. Conditional analyses provided evidence for secondary signals in LEPR, IL1RN and HNF1A, and for multiple independent signals in CRP and APOE. We identified novel variants and loci associated with CRP levels, generalized known CRP associations to a multiethnic study population, refined association signals at several loci and found evidence for multiple independent signals at several well-known loci. This study demonstrates the benefit of conducting inclusive genetic association studies in large multiethnic populations

[O III] emission line as a tracer of star-forming galaxies at high redshifts: comparison between Hα and [O III] emitters at z=2.23 in HiZELS

We investigate the properties of z = 2.23 Hα and [O III] λ5007 emitters using the narrow-band-selected samples obtained from the High-z Emission Line Survey. We construct two samples of the Hα and [O III] emitters and compare their integrated physical properties. We find that the distribution of stellar masses, dust extinction, star formation rates (SFRs), and specific SFRs (sSFRs) is not statistically different between the two samples. When we separate the full galaxy sample into three subsamples according to the detections of the Hα and/or [O III] emission lines, most of the sources detected with both Hα and [O III] show log(sSFRUV) ≳ −9.5. The comparison of the three subsamples suggests that sources with strong [O III] line emission tend to have the highest star-forming activity out all galaxies that we study. We argue that the [O III] emission line can be used as a tracer of star-forming galaxies at high redshift, and that it is especially useful to investigate star-forming galaxies at z > 3, for which Hα emission is no longer observable from the ground

What's Seneca to Him? Senecan Shakespeare

Although for Scaliger Seneca was even greater than Euripides, it has often been acknowledged that Romantic writers have bequeathed us a negative legacy that has debased him as second-rate, imitative, and inauthentic compared to Greek authors. Such harsh criticism has distorted for centuries “our understanding of Shakespeare’s engagement with Senecan tragedy”, so much so that “even if Shakespeareans now acknowledge Seneca to be important for early modern tragedy we remain unlikely to see his influence as an especially robust or interesting one” (Perry 2021, 2). If T.S. Eliot inaugurated an interpretation of the linkage between Seneca and Shakespeare through interest in inwardness and self-dramatisation, the foregrounding of the self (or of Braden’s “autarkic selfhood”, 1985) is made possible only by situating this experience within the playworld, in spaces visualising and framing the surfacing of unconscious desires and repressed passions beyond plot structures. By focusing on questions of authorial construction, appropriation, domestication, but also ‘improvement’ and expansion, this issue engages with these different threads of confluences, aware of, and dallying with, perspectival mobility about what constructing Senecan Shakespeare may mean