833 research outputs found
Exceptional quantum subgroups for the rank two Lie algebras B2 and G2
Exceptional modular invariants for the Lie algebras B2 (at levels 2,3,7,12)
and G2 (at levels 3,4) can be obtained from conformal embeddings. We determine
the associated alge bras of quantum symmetries and discover or recover, as a
by-product, the graphs describing exceptional quantum subgroups of type B2 or
G2 which encode their module structure over the associated fusion category.
Global dimensions are given.Comment: 33 pages, 27 color figure
Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background
The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is universal for the studied pathogen; it has seldom been clarified whether drug-resistance mechanisms vary with the pathogen's genotype. Nevertheless this is of critical importance in gaining an understanding of the complexity of this global threat and in underpinning epidemiological surveillance of pathogen drug resistance in the field. This study aimed to assess the molecular and phenotypic heterogeneity that emerges in natural parasite populations under drug treatment pressure. We studied lines of the protozoan parasite Leishmania (L.) donovani with differential susceptibility to antimonial drugs; the lines being derived from clinical isolates belonging to two distinct genetic populations that circulate in the leishmaniasis endemic region of Nepal. Parasite pathways known to be affected by antimonial drugs were characterised on five experimental levels in the lines of the two populations. Characterisation of DNA sequence, gene expression, protein expression and thiol levels revealed a number of molecular features that mark antimonial-resistant parasites in only one of the two populations studied. A final series of in vitro stress phenotyping experiments confirmed this heterogeneity amongst drug-resistant parasites from the two populations. These data provide evidence that the molecular changes associated with antimonial-resistance in natural Leishmania populations depend on the genetic background of the Leishmania population, which has resulted in a divergent set of resistance markers in the Leishmania populations. This heterogeneity of parasite adaptations provides severe challenges for the control of drug resistance in the field and the design of molecular surveillance tools for widespread applicability
Higher education in Indonesia: Contemporary challenges in governance, access, and quality
This chapter presents the development of Indonesian higher education since its origins to current
challenges in the fields of governance, autonomy, access, equity, quality, and
internationalization. Indonesia has a massive and diversified tertiary education, including
experiments in community colleges and online programs. The higher educational system remains
mainly centralized, with the exception of some reforms towards financial autonomy. Insufficient
public funding hinders the capacity to provide adequate teaching, research, and facilities among
other aspects. The consequential rise in student fees contributes to an overrepresentation of
students from Java, urban centers, and higher social classes
ENERGY VALORIZATION OF OLIVE WASTE WATER, THEIR SLUDGE AND TREATMENT BY METHANE PRODUCTION
The anaerobic digestion of oil wastes water and the sludges of their treatment is a biological process that allows the production of energy in the form of biogas. Our study is based on the comparison of the methanogenic capacity between the biogas of the oil wastes water and the sludges of their treatment.Olive wastes water were previously treated by electrocoagulation and adsorption in optimal conditions. The sludge generated by the various treatments, estimated at 50 g/L of oil wastes water, is in turn treated by anaerobic digestion.The production of methane from the two wastes is accompanied by the reduction of their pollutant load evaluated in non-biodegradable organic matter, polyphenols and fat respectively by 39 %, 45 % and 39 % for sludge of oil wastes water and 36 %, 31 % and 39 % for oil waste water; a total yield of pollutant load of oil waste water from about 75 % to 78 %. The total amount of methane produced for 30 days and 49 days respectively by olive mill wastewater and their treatment sludge is 300.7 cm3/L and 889.9 cm3/L is an energy equivalent of 2.92 Wh/L and 8.72 Wh/L.The use of the anaerobic digestion process of oil wastes water treatment sludge is efficient and cost-effective for biogas production while eliminating their harmful effects on the environment.
Mapping on slope seepage problem using Electrical Resistivity Imaging (ERI)
The stability of slope may influenced by several factors such as its geomaterial properties, geometry and environmental factors. Problematic slope due to seepage phenomenon will influenced the slope strength thus promoting to its failure. In the past, slope seepage mapping suffer from several limitation due to cost, time and data coverage. Conventional engineering tools to detect or mapped the seepage on slope experienced those problems involving large and high elevation of slope design. As a result, this study introduced geophysical tools for slope seepage mapping based on electrical resistivity method. Two spread lines of electrical resistivity imaging were performed on the slope crest using ABEM SAS 4000 equipment. Data acquisition configuration was based on long and short arrangement, schlumberger array and 2.5 m of equal electrode spacing interval. Raw data obtained from data acquisition was analyzed using RES2DINV software. Both of the resistivity results show that the slope studied consists of three different anomalies representing top soil (200 – 1000 Ωm), perched water (10 – 100 Ωm) and hard/dry layer (> 200 Ωm). It was found that seepage problem on slope studied was derived from perched water zones with electrical resistivity value of 10 – 100 Ωm. Perched water zone has been detected at 6 m depth from the ground level with varying thickness at 5 m and over. Resistivity results have shown some good similarity output with reference to borehole data, geological map and site observation thus verified the resistivity results interpretation. Hence, this study has shown that the electrical resistivity imaging was applicable in slope seepage mapping which consider efficient in term of cost, time, data coverage and sustainability
Role of PACAP and VIP Signalling in Regulation of Chondrogenesis and Osteogenesis
Pituitary adenylate cyclase activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are multifunctional proteins that can regulate diverse physiological processes. These are also regarded as neurotrophic and anti-inflammatory substances in the CNS, and PACAP is reported to prevent harmful effects of oxidative stress. In the last decade more and more data accumulated on the similar function of PACAP in various tissues, but its cartilage- and bone-related presence and functions have not been widely investigated yet. In this summary we plan to verify the presence and function of PACAP and VIP signalling tool kit during cartilage differentiation and bone formation. We give evidence about the protective function of PACAP in cartilage regeneration with oxidative or mechanically stress and also with the modulation of PACAP signalling in vitro in osteogenic cells. Our observations imply the therapeutic perspective that PACAP might be applicable as a natural agent exerting protecting effect during joint inflammation and/or may promote cartilage regeneration during degenerative diseases of articular cartilage
From laboratory experiments to LISA Pathfinder: achieving LISA geodesic motion
International audienceThis paper presents a quantitative assessment of the performance of the upcoming LISA Pathfinder geodesic explorer mission. The findings are based on the results of extensive ground testing and simulation campaigns using flight hardware and flight control and operations algorithms. The results show that, for the central experiment of measuring the stray differential acceleration between the LISA test masses, LISA Pathfinder will be able to verify the overall acceleration noise to within a factor two of the LISA requirement at 1 mHz and within a factor 10 at 0.1 mHz. We also discuss the key elements of the physical model of disturbances, coming from LISA Pathfinder and ground measurement, that will guarantee the LISA performance
Impact of composts prepared from olive waste on the growth and production parameters of some fruit trees
In agriculture, the use of organic amendments allows a better sustainability and productivity of the crop by improving the quality and structure of the soil, due to their richness in organic matter and nutrients such as phosphorus, nitrogen, potassium, etc. This study aims to evaluate the effect of two composts of different compositions on the growth and yield of three types of trees: peach, pear and orange. The experimental design used is a randomized block with three replications. The treatment of trees was carried out by four types of amendments which were composts with olive waste (OW), olive mill wastewater (OMW), manure (M) and NPK fertilizer (F) of type 10-15-12. Their fertilizing power was evaluated by monitoring the morphological parameters of plant growth: height, trunk diameter, number of branches, and those of production including size, weight of fruit and yield. The obtained outcomes reveal that the two composts have a very highly significant effect on the investigated parameters. The production was recorded only in peach trees with a total yield of 31.5 t/ha; 25.5 t/ha; 22.5 t/ha; 18.5 t/ha, respectively for OW, OMW, F and M
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