The privacy and control paradoxes in the context of smartphone apps

This research examines how various factors, such as the degree of e-privacy concerns and control over data access permissions, can influence a user's intention to install a smartphone app. We conducted two survey-based experiments with 441 participants. In each experiment, we manipulated the degree of control over the number and type of data access permissions granted to different fictional apps. In Study 1, participants were informed about the set of permissions the apps required. In Study 2, participants indicated which individual permissions they were willing to grant to the apps. In both experiments, we assessed the level of e-privacy concerns, perceived app importance, and the intention to install the apps. The results suggest that the type of app plays a central role in determining both the perceived benefit of installing the app and the level of e-privacy concerns. The intention to install an app is more strongly associated with perceived app importance than with e-privacy concerns (especially when app importance is high, and users have explicit control over which specific data access permissions they want to grant). The implications of these results are discussed regarding psychological factors involved in app installation decision-making process and the importance of promoting data protection by design

EFEITOS DE UM AMBIENTE VIRTUAL E DO TIPO DE CONSEQUÊNCIAS SOBRE A APRENDIZAGEM DE DISCRIMINAÇÕES SIMPLES EM PRÉ-ESCOLARES

The present study evaluated the effects of a virtual environment and the type of consequences for correct responses, on learning process of visual simple discriminations and reversals, and on the maintenance of preschool children in experimental situation. The virtual environment was a dynamic scenario presented on the computer screen, which simulated a forest with trees, on which the stimuli were presented. Experiments 1 and 2 compared the effects of Conditions A and B. Both conditions used the virtual environment, however, the consequence for correct responses were cartoon videos in Condition A, and an auditory visual animation with stars in Condition B. The results indicated that using videos as consequences for correct responses produced errorless and maintained children committed in experimental situation. Experiment 3 compared effects of Conditions A and C. Both conditions used videos as consequences for correct responses; however, in Condition A the scenario was the virtual environment, while in Condition C it was a white static background. The results indicated that the scenarios did not produced differential effects on variables considered dependents. Together, the results indicated that the type of consequences were more decisive on producing learning than the virtual environment. Keywords: virtual environment, reinforcement, simple discrimination, discrimination reversal, children.   Este estudo avaliou os efeitos de um ambiente virtual e do tipo de consequência para acertos, sobre o processo de aprendizagem e a reversão de discriminações simples visuais, e sobre a manutenção de pré-escolares em situação experimental. O ambiente virtual era um cenário dinâmico apresentado na tela do computador, que simulava uma floresta com árvores sobre as quais eram posicionados os estímulos. Os experimentos 1 e 2 compararam os efeitos das condições A e B. Ambas empregaram o ambiente virtual, porém, como consequência para cada resposta correta, na Condição A eram exibidos trechos de vídeos de desenhos animados, e na Condição B, uma breve animação de estrelas coloridas com sons. Os resultados dos experimentos apontaram que o emprego de vídeos produziu menos erros e manteve as crianças engajadas em situação experimental. O Experimento 3 comparou os efeitos das condições A e C. Ambas empregaram vídeos como consequências para acertos; porém, na Condição A o cenário era o ambiente virtual, e na Condição C, um fundo branco e estático. Os resultados indicaram que os cenários não tiveram efeitos diferenciais sobre as variáveis consideradas dependentes. Em conjunto, os resultados indicaram que os tipos de consequências foram mais determinantes da aprendizagem do que o emprego do ambiente virtual. Palavras-chave: ambiente virtual, reforço, discriminação simples, reversão de discriminação, crianças.

Factores de riesgo cardiovascular en pacientes pediátricos después de un año de trasplante renal

OBJECTIVE: To identify the prevalence of diabetes mellitus and the presence of cardiovascular risk factors in pediatric patients after one year of renal transplant. METHODS: This was an exploratory retrospective study. Data were collected from 111 medical records of pediatric patients (aged 0 to incomplete 18 year old) who underwent renal transplant at both the Hospital do Rim and Hypertension (Renal and High Blood Pressure Hospital) and the São Paulo Hospital of the Federal University of São Paulo between January 2000 and January 2006. RESULTS: A half of patients (50.5%) used high blood pressure medications prior to undergoing renal transplant. A year after renal transplant the use of high blood pressure medications by the pediatric patients was reduced by 28%. Before transplant, 13.5% of the patients were overweighed and did not have any significant changes in their weight after the transplant (12.6%). There was an increase in the number of overweight patients after a year of renal transplant by 50.0%. Approximately 1.0% of the patients developed diabetes mellitus after the renal transplant. CONCLUSION: Obesity, high blood pressure, and diabetes mellitus were common conditions among pediatric patients after renal transplant.OBJETIVO: Identificar la frecuencia de diabetes mellitus y la presencia de factores de riesgo cardiovascular en pacientes pediátricos después de un año de trasplante renal. MÉTODOS: Estudio retrospectivo, de orden documental y exploratorio, realizado de enero de 2000 a enero de 2006, abarcando 111 fichas de pacientes pediátricos (0 a 18 años incompletos) sometidos a trasplante renal en el Hospital del Riñón e Hipertensión y en el Hospital São Paulo de la Universidad Federal de São Paulo. RESULTADOS: Fueron analizados 111 pacientes, 50,5% utilizaban anti-hipertensores antes del trasplante renal. Un año después este número cayó para 28%. En el pre-trasplante, 13,5% pacientes presentaron sobrepeso y después de un año no hubo alteración importante (12,6%). El número de pacientes obesos aumentó 50% después de un año de trasplante renal. Aproximadamente 1% de los niños desarrollaron diabetes mellitus después del trasplante renal. CONCLUSIÓN: La presencia de exceso de peso (sobrepeso y obesidad), hipertensión arterial y diabetes mellitus son frecuentes en pacientes pediátricos después del trasplante renal.OBJETIVO: Identificar a frequência de diabetes mellitus e a presença de fatores de risco cardiovascular em pacientes pediátricos após um ano de transplante renal. MÉTODOS: Estudo retrospectivo, de cunho documental e exploratório, realizado de janeiro de 2000 a janeiro de 2006, abrangendo 111 prontuários de pacientes pediátricos (0 a 18 anos incompletos) submetidos a transplante renal no Hospital do Rim e Hipertensão e no Hospital São Paulo da Universidade Federal de São Paulo (UNIFESP). RESULTADOS: Foram analisados 111 pacientes, 50,5% utilizavam anti-hipertensivos antes do transplante renal. Um ano após este número caiu para 28%. No pré-transplante 13,5% pacientes apresentaram sobrepeso e após um ano não houve alteração importante (12,6%). O número de pacientes obesos aumentou 50% após um ano de transplante renal. Aproximadamente 1% das crianças desenvolveram diabetes mellitus pós-tranplante renal. CONCLUSÃO: A presença de excesso de peso (sobrepeso e obesidade), hipertensão arterial e diabetes mellitus são freqüentes em pacientes pediátricos pós-tranplante renal.Associação Beneficente São CristóvãoUNIFESPCentro Universitário São CamiloHemocentro do Hospital Oswaldo CruzHospital do Rim e HipertensãoHospital São PauloUNIFESP Departamento de PediatriaUNIFESP Hospital do Rim e Hipertensão Ambulatório de Transplante RenalUNIFESP Departamento de MedicinaHospital do Rim e Hipertensão Unidade de TransplanteUNIFESPHospital São PauloUNIFESP, Depto. de PediatriaUNIFESP, Hospital do Rim e Hipertensão Ambulatório de Transplante RenalUNIFESP, Depto. de MedicinaSciEL

HIV infection: time from diagnosis to initiation of antiretroviral therapy in Portugal, a multicentric study

© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).The benefits of antiretroviral therapy (ART) for persons living with HIV (PLWH) are well established. Rapid ART initiation can lead to improved clinical outcomes. Portugal has one of the highest rates of new HIV diagnoses in the European Union, and an average time until ART initiation above the recommendations established by the national guideline according to data from the first two years after its implementation in 2015, with no more recent data available after that. This study aimed to evaluate time from the first hospital appointment until ART initiation among newly diagnosed HIV patients in Portugal between 2017 and 2018, to investigate differences between hospitals, and to understand the experience of patient associations in supporting the navigation of PLWH throughout referral and linkage to the therapeutic process. To answer to these objectives, a twofold design was followed: a quantitative approach, with an analysis of records from five Portuguese hospitals, and a qualitative approach, with individual interviews with three representatives of patient associations. Overall, 847 and 840 PLWH initiated ART in 2017 and in 2018, respectively, 21 days (median of the two years) after the first appointment, with nearly half coming outside the mainstream service for hospital referral, and with observed differences between hospitals. In 2017–2018, only 38.0% of PLWH initiated ART in less than 14 days after the first hospital appointment. From the interviews, barriers of administrative and psychosocial nature were identified that may hinder access to ART. Patient associations work to offer a tailored support to patients’ navigation within the health system, which can help to reduce or overcome those potential barriers. Indicators related to time until ART initiation can be used to monitor and improve access to specialized care of PLWH.info:eu-repo/semantics/publishedVersio

Dysarthria in hereditary spastic paraplegia type 4

Objective: To describe the speech pattern of patients with hereditary Spastic Paraplegia type 4 (SPG4) and correlated it with their clinical data. Methods: Cross-sectional study was carried out in two university hospitals in Brazil. Two groups participated in the study: the case group (n = 28) with a confirmed genetic diagnosis for SPG4 and a control group (n = 17) matched for sex and age. The speech assessment of both groups included: speech task recording, acoustic analysis, and auditory-perceptual analysis. In addition, disease severity was assessed with the Spastic Paraplegia Rating Scale (SPRS). Results: In the auditory-perceptual analysis, 53.5% (n = 15) of individuals with SPG4 were dysarthric, with mild to moderate changes in the subsystems of phonation and articulation. On acoustic analysis, SPG4 subjects’ performances were worse in measurements related to breathing (maximum phonation time) and articulation (speech rate, articulation rate). The articulation variables (speech rate, articulation rate) are related to the age of onset of the first motor symptom. Conclusion: Dysarthria in SPG4 is frequent and mild, and it did not evolve in conjunction with more advanced motor diseases. This data suggest that diagnosed patients should be screened and referred for speech therapy evaluation and those pathophysiological mechanisms of speech involvement may differ from the length-dependent degeneration of the corticospinal tract

Insecticide resistance in Aedes aegypti populations from Ceará, Brazil

<p>Abstract</p> <p>Background</p> <p>Organophosphates and pyrethroids are used widely in Brazil to control <it>Aedes aegypti</it>, the main vector of dengue viruses, under the auspices of the National Programme for Dengue Control. Resistance to these insecticides is widespread throughout Brazil. In Ceará the vector is present in 98% of districts and resistance to temephos has been reported previously. Here we measure resistance to temephos and the pyrethroid cypermethrin in three populations from Ceará and use biochemical and molecular assays to characterise resistance mechanisms.</p> <p>Results</p> <p>Resistance to temephos varied widely across the three studied populations, with resistance ratios (RR₉₅) of 7.2, 30 and 192.7 in Juazeiro do Norte, Barbalha and Crato respectively. The high levels of resistance detected in Barbalha and Crato (RR₉₅≥ 30) imply a reduction of temephos efficacy, and indeed in simulated field tests reduced effectiveness was observed for the Barbalha population. Two populations (Crato and Barbalha) were also resistant to cypermethrin, whilst Juazeiro do Norte showed only an altered susceptibility. The <it>Ile1011Met kdr </it>mutation was detected in all three populations and <it>Val1016Ile </it>in Crato and Juazeiro do Norte. <it>1011Met </it>was significantly associated with resistance to cypermethrin in the Crato population. Biochemical tests showed that only the activity of esterases and GSTs, among the tested detoxification enzymes, was altered in these populations when compared with the Rockefeller strain.</p> <p>Conclusions</p> <p>Our results demonstrate that two <it>A. aegypti </it>populations from Ceará are under strong selection pressure by temephos, compromising the field effectiveness of this organophosphate. Our results also provide evidence that the process of reducing resistance to this larvicide in the field is difficult and slow and may require more than seven years for reversal. In addition, we show resistance to cypermethrin in two of the three populations studied, and for the first time the presence of the allele <it>1016Ile </it>in mosquito populations from northeastern Brazil. A significant association between <it>1011M</it>et and resistance was observed in one of the populations. Target-site mechanisms seem not to be implicated in temephos resistance, reinforcing the idea that for the studied populations, detoxification enzymes most likely play a major role in the resistance to this insecticide.</p

Preschoolers inclusion of objects in classes of equivalent photos

The present study aimed to investigate whether preschool children would acquire arbitrary conditional discriminations between pictures of objects, whether they would form equivalence classes between the photos and if they would then incorporate the objects themselves into classes (with no direct teaching of relations between them). An additional objective was to determine whether children would group together schematic drawings of objects in the same classes. Six children around the age of four participated. Initially, tests aimed to evaluate generalized repertoires of conditional discriminations by identity (between photos and between objects). Next, conditional discriminations were taught that served as a baseline for forming three equivalence classes between photographs of abstract objects (without names). Half of the participants underwent the Sample as Node Training (AB / AC) and the other half the Linear- Series Training (AB / BC). Multiple probes that assessed both baseline relations, as well as derived relations (symmetries and equivalences), were used to evaluate the effects of teaching on the learning process and the acquisition of discriminations, as well as the emergence of derived relations. Following the emergence of classes with the use of photos, arbitrary conditional discrimination tests were performed between objects and between objects and photos, in order to assess the expansion of the original classes. Lastly, the children underwent conditional discrimination tests between schematic figures. All participants accurately performed identity-matching conditional discriminations between photos and between objects, and conditional discrimination between objects and their photos. In the probes prior to the teaching participants answered at random in the baseline (AB, and AC or BC), symmetry (BA and CA or CB) and equivalence relations (BC and CB; or AC and CA). After the acquisition of the first base line (AB), the probes showed that AB was maintained as well as the emergence of BA symmetries. Following the second baseline (AC or BC), most participants maintained AC (or BC) and presented the symmetries (CA or CB); however, deterioration of AB and BA occurred for four children, whereas one child formed equivalence classes. For the others, the equivalence relations emerged after the teaching of mixed baselines (training simultaneously with AB and AC or with AB and BC). Three participants showed positive results in tests of equivalence between objects, and exhibited expansion classes while simultaneously matching objects and photos. Two responded according to the classes in the tests with schematic figures. Apparently, the training structure produced no systematic effects neither on the emergence of relations between photos, nor on the expansion of classes. The results carry important implications for understanding the symbolic behavior involving levels of correspondence between two-dimensional and tridimensional stimuli. Methodological limitations should be addressed in future studies which evaluate the role of critical variables for the photos-objects equivalence based on the teaching involving only one of the stimuli modalities.Financiadora de Estudos e ProjetosO presente trabalho teve por objetivo verificar se crianças pré-escolares aprenderiam discriminações condicionais arbitrárias entre fotografias de objetos, se formariam classes de equivalência entre as fotos e se, em seguida, incorporariam os próprios objetos às classes (sem ensino direto de relações entre eles). Um objetivo adicional foi verificar se as crianças agrupariam desenhos esquemáticos dos objetos nas mesmas classes. Participaram seis crianças com cerca de quatro anos de idade. Inicialmente, testes avaliaram repertórios generalizados de discriminações condicionais por identidade (entre fotos e entre objetos). Em seguida, foram ensinadas discriminações condicionais que serviram como linha de base para a formação de três classes de equivalência entre fotografias de objetos abstratos (sem nomes). Metade dos participantes realizou o Treino de Modelo como Nódulo (AB/AC) e outra metade o Treino Linear (AB/BC). Um delineamento de múltiplas sondagens, que avaliava tanto relações de linha de base, quanto relações derivadas (simetrias e equivalências), foi empregado para avaliar os efeitos do ensino sobre a aprendizagem e a retenção de discriminações, bem como sobre a emergência de relações derivadas. Após a emergência das classes com fotos, foram realizados testes de discriminação condicional arbitrária entre objetos, e entre fotos e objetos, com o objetivo de avaliar a expansão das classes originais. Por último, as crianças realizaram testes de discriminação condicional entre as figuras esquemáticas. Todos os participantes realizaram acuradamente discriminações condicionais de identidade entre fotos e entre objetos, e discriminações condicionais entre objetos e suas fotos. Nas sondas antes do ensino os participantes responderam ao acaso nas relações de linha de base (AB, e AC ou BC), de simetria (BA e CA ou CB) e de equivalência (BC e CB; ou AC e CA). Após a aprendizagem da primeira linha de base (AB), as sondas mostraram manutenção de AB e emergência das simetrias BA. Após a segunda linha de base (AC ou BC), a maioria dos participantes manteve AC (ou BC) e apresentou as simetrias (CA ou CB); porém para quatro crianças ocorreu deterioração de AB e BA, enquanto uma criança formou classes de equivalência. Para os demais as relações de equivalência emergiram após o ensino da linha de base cheia (treino misto simultâneo com AB e AC ou BC). Três participantes apresentaram resultados positivos nos testes de equivalência entre objetos, e mostraram expansão classes, relacionando simultaneamente objetos e fotos. Dois responderam de acordo com as classes nos testes com figuras esquemáticas. A estrutura de treino aparentemente não produziu efeitos sistemáticos sobre a emergência de relações entre fotos, nem sobre a expansão das classes. Os resultados têm importantes implicações para a compreensão do comportamento simbólico envolvendo níveis de correspondência entre estímulos bi e tridimensionais. Limitações metodológicas deverão ser equacionadas em estudos futuros que avaliem o papel de variáveis críticas para a equivalência fotos-objetos a partir do ensino com apenas uma das modalidades de estímulos

The privacy and control paradoxes in the context of smartphone apps

This research examines how various factors, such as the degree of e-privacy concerns and control over data access permissions, can influence a user’s intention to install a smartphone app. We conducted two survey-based experiments with 441 participants. In each experiment, we manipulated the degree of control over the number and type of data access permissions granted to dierent fictional apps. In Study 1, participants were informed about the set of permissions the apps required. In Study 2, participants indicated which individual permissions they were willing to grant to the apps. In both experiments, we assessed the level of e-privacy concerns, perceived app importance, and the intention to install the apps. The results suggest that the type of app plays a central role in determining both the perceived benefit of installing the app and the level of e-privacy concerns. The intention to install an app is more strongly associated with perceived app importance than with e-privacy concerns (especially when app importance is high, and users have explicit control over which specific data access permissions they want to grant). The implications of these results are discussed regarding psychological factors involved in app installation decision-making process and the importance of promoting data protection by design

The privacy and control paradoxes in the context of smartphone apps

This research examines how various factors, such as the degree of e-privacy concerns and control over data access permissions, can influence a user's intention to install a smartphone app. We conducted two survey-based experiments with 441 participants. In each experiment, we manipulated the degree of control over the number and type of data access permissions granted to different fictional apps. In Study 1, participants were informed about the set of permissions the apps required. In Study 2, participants indicated which individual permissions they were willing to grant to the apps. In both experiments, we assessed the level of e-privacy concerns, perceived app importance, and the intention to install the apps. The results suggest that the type of app plays a central role in determining both the perceived benefit of installing the app and the level of e-privacy concerns. The intention to install an app is more strongly associated with perceived app importance than with e-privacy concerns (especially when app importance is high, and users have explicit control over which specific data access permissions they want to grant). The implications of these results are discussed regarding psychological factors involved in app installation decision-making process and the importance of promoting data protection by design