176 research outputs found

    Neutron total cross sections on nuclei at Fermilab energies

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    We have measured total cross sections for neutrons on protons, deuteriom, beryllium, carbon, aluminium, iron, copper, cadmium, tungsten, lead, and uranium for momenta between 30 and 300 GeV/c. The measurements were carried out in a small-angle neutral beam at Fermilab. Typical accuracy of the data is 0.5 to 1%. The cross sections are consistent with an A0.77+/-0.01 dependence over the entire momentum range. The cross sections are compared with theoretical predictions. Agreement is found only if inelastic screening is included. Nuclear radii obtained from our data are in good agreement with previous determinations.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/22036/1/0000454.pd

    On inconsistency of experimental data on primary nuclei spectra with sea level muon intensity measurements

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    For the first time a complete set of the most recent direct data on primary cosmic ray spectra is used as input into calculations of muon flux at sea level in wide energy range EÎŒ=1−3⋅105E_\mu=1-3\cdot10^5 GeV. Computations have been performed with the CORSIKA/QGSJET and CORSIKA/VENUS codes. The comparison of the obtained muon intensity with the data of muon experiments shows, that measurements of primary nuclei spectra conform to sea level muon data only up to several tens of GeV and result in essential deficit of muons at higher energies. As it follows from our examination, uncertainties in muon flux measurements and in the description of nuclear cascades development are not suitable to explain this contradiction, and the only remaining factor, leading to this situation, is underestimation of primary light nuclei fluxes. We have considered systematic effects, that may distort the results of the primary cosmic ray measurements with the application of the emulsion chambers. We suggest, that re-examination of these measurements is required with the employment of different hadronic interaction models. Also, in our point of view, it is necessary to perform estimates of possible influence of the fact, that sizable fraction of events, identified as protons, actually are antiprotons. Study of these cosmic ray component begins to attract much attention, but today nothing definite is known for the energies >40>40 GeV. In any case, to realize whether the mentioned, or some other reasons are the sources of disagreement of the data on primaries with the data on muons, the indicated effects should be thoroughly analyzed

    Atmospheric Muon Flux at Sea Level, Underground, and Underwater

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    The vertical sea-level muon spectrum at energies above 1 GeV and the underground/underwater muon intensities at depths up to 18 km w.e. are calculated. The results are particularly collated with a great body of the ground-level, underground, and underwater muon data. In the hadron-cascade calculations, the growth with energy of inelastic cross sections and pion, kaon, and nucleon generation in pion-nucleus collisions are taken into account. For evaluating the prompt muon contribution to the muon flux, we apply two phenomenological approaches to the charm production problem: the recombination quark-parton model and the quark-gluon string model. To solve the muon transport equation at large depths of homogeneous medium, a semi-analytical method is used. The simple fitting formulas describing our numerical results are given. Our analysis shows that, at depths up to 6-7 km w. e., essentially all underground data on the muon intensity correlate with each other and with predicted depth-intensity relation for conventional muons to within 10%. However, the high-energy sea-level data as well as the data at large depths are contradictory and cannot be quantitatively decribed by a single nuclear-cascade model.Comment: 47 pages, REVTeX, 15 EPS figures included; recent experimental data and references added, typos correcte

    Sustainability appraisal: Jack of all trades, master of none?

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    Sustainable development is a commonly quoted goal for decision making and supports a large number of other discourses. Sustainability appraisal has a stated goal of supporting decision making for sustainable development. We suggest that the inherent flexibility of sustainability appraisal facilitates outcomes that often do not adhere to the three goals enshrined in most definitions of sustainable development: economic growth, environmental protection and enhancement, and the wellbeing of the human population. Current practice is for sustainable development to be disenfranchised through the interpretation of sustainability, whereby the best alternative is good enough even when unsustainable. Practitioners must carefully and transparently review the frameworks applied during sustainability appraisal to ensure that outcomes will meet the three goals, rather than focusing on a discourse that emphasises one or more goals at the expense of the other(s)

    Neutron-proton differential cross sections in the range 70 to 400 GeV/c

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    We report the results of an experiment which measured np elastic scattering differential cross sections over a range in -t from 0.15 to ~3.6 (GeV/c)2 for incident neutron momenta from 70 to 400 GeV/c. We find the logarithmic slope parameter, evaluated at -t = 0.2 (GeV/c)2, to be consistent with existing proton-proton parametrizations. The data exhibit a dip in the cross section near -t = 1.4 (GeV/c)2 for incident neutron momenta above 200 GeV/c. For neutron momenta less than 280 GeV/c, the neutron-proton cross sections are found to be higher than existing proton-proton data in the range 0.7 [les] -t [les] 1.3 (GeV/c)2 which is in contradiction to most Regge predictions.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/23627/1/0000590.pd

    Measurement of the Atmospheric Muon Spectrum from 20 to 3000 GeV

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    The absolute muon flux between 20 GeV and 3000 GeV is measured with the L3 magnetic muon spectrometer for zenith angles ranging from 0 degree to 58 degree. Due to the large exposure of about 150 m2 sr d, and the excellent momentum resolution of the L3 muon chambers, a precision of 2.3 % at 150 GeV in the vertical direction is achieved. The ratio of positive to negative muons is studied between 20 GeV and 500 GeV, and the average vertical muon charge ratio is found to be 1.285 +- 0.003 (stat.) +- 0.019 (syst.).Comment: Total 32 pages, 9Figure

    Targeting of highly conserved Dengue virus sequences with anti-Dengue virus trans-splicing group I introns

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    <p>Abstract</p> <p>Background</p> <p>Dengue viruses (DENV) are one of the most important viral diseases in the world with approximately 100 million infections and 200,000 deaths each year. The current lack of an approved tetravalent vaccine and ineffective insecticide control measures warrant a search for alternatives to effectively combat DENV. The <it>trans</it>-splicing variant of the <it>Tetrahymena thermophila </it>group I intron catalytic RNA, or ribozyme, is a powerful tool for post-transcriptional RNA modification. The nature of the ribozyme and the predictability with which it can be directed makes it a powerful tool for modifying RNA in nearly any cell type without the need for genome-altering gene therapy techniques or dependence on native cofactors.</p> <p>Results</p> <p>Several anti-DENV Group I <it>trans</it>-splicing introns (αDENV-GrpIs) were designed and tested for their ability to target DENV-2 NGC genomes <it>in situ</it>. We have successfully targeted two different uracil bases on the positive sense genomic strand within the highly conserved 5'-3' cyclization sequence (CS) region common to all serotypes of DENV with our αDENV-GrpIs. Our ribozymes have demonstrated ability to specifically <it>trans</it>-splice a new RNA sequence downstream of the targeted site <it>in vitro </it>and in transfected insect cells as analyzed by firefly luciferase and RT-PCR assays. The effectiveness of these αDENV-GrpIs to target infecting DENV genomes is also validated in transfected or transformed Aedes mosquito cell lines upon infection with unattenuated DENV-2 NGC.</p> <p>Conclusions</p> <p>Analysis shows that our αDENV-GrpIs have the ability to effectively <it>trans</it>-splice the DENV genome <it>in situ</it>. Notably, these results show that the αDENV-GrpI 9v1, designed to be active against all forms of Dengue virus, effectively targeted the DENV-2 NGC genome in a sequence specific manner. These novel αDENV-GrpI introns provide a striking alternative to other RNA based approaches for the transgenic suppression of DENV in transformed mosquito cells and tissues.</p

    Calculation of the Flux of Atmospheric Neutrinos

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    Atmospheric neutrino-fluxes are calculated over the wide energy range from 30 MeV to 3,000 GeV for the study of neutrino-physics using the data from underground neutrino-detectors. The atmospheric muon-flux at high altitude and at sea level is studied to calibrate the neutrino-fluxes at low energies and high energies respectively. The agreement of our calculation with observations is satisfactory. The uncertainty of atmospheric neutrino-fluxes is also studied.Comment: 51 page
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