Optimisation d'un système hybride innovateur pour camion à ordures

Un système hybride hydraulique parallèle à pression assistée (SHHPPA) a déjà été identifié dans la littérature comme étant très efficace pour une application sur des camions à ordures. Par contre, ce système de base comporte quelques lacunes en termes d'efficacité énergétique. Les travaux d'études de ce mémoire présentent une version innovatrice et optimisée de ce système. Son optimisation a été réalisée à l'aide d'un modèle de simulation numérique utilisant des données d'entrées enregistrées sur un camion à ordures opérant en conditions réelles. L'analyse de 756 différentes configurations, effectuée à l'aide de ce modèle a déterminé que la configuration optimale permet de retransmettre 40,7% de l'énergie de freinage disponible à la prise de puissance du moteur à combustion interne. Ceci correspond approximativement à une réduction de la consommation de carburant de 15,8 %

Detection of the Galaxy Lensing the Doubly-imaged Quasar SBS 1520+530

H band observations with a spatial resolution of 0.15" carried out with the Canada-France-Hawaii Telescope adaptive optics system show a galaxy between the components of the double BAL quasar SBS 1520+530, thereby confirming this system as a gravitational lens. The galaxy is located 0.40" from the fainter of the two QSO images and is offset 0.12" from the line joining them. The H magnitude of the lensing galaxy is ~1 mag fainter than expected from the velocity dispersion derived for the lensing galaxy were it at z = 0.71 or z = 0.81, the redshifts of the two absorption line systems.Comment: 11 pages latex including one table and 2 postscript figures. Corrected typo. Accepted by AJ. Also available at http://www.hia.nrc.ca/science/preprint/preprint.htm

NASA Land Information System (LIS) Water Availability to Support Reclamation ET Estimation

The U.S. Bureau of Reclamation identified the remote sensing of evapotranspiration (ET) as an important water flux for study and designated a test site in the Lower Colorado River basin. A consortium of groups will work together with the goal to develop more accurate and cost effective techniques using the enhanced spatial and temporal coverage afforded by remote sensing. ET is a critical water loss flux where improved estimation should lead to better management of Reclamation responsibilities. There are several areas where NASA satellite and modeling data may be useful to meet Reclamation's objectives for improved ET estimation. In this paper we outline one possible contribution to use NASA's data integration capability of the Land Information System (LIS) to provide a merger of observational (in situ and satellite) with physical process models to provide estimates of ET and other water availability outputs (e.g., runoff, soil moisture) retrospectively, in near real-time, and also providing short-term predictions

Tackling loneliness evidence review

n 2018, some of us (Barreto, Matthews, Qualter, Victor) contributed to an ESRC Think Piece on Loneliness and recommended that there needed to be increased investment from UKRI for research examining loneliness. We highlighted key gaps in the evidence and suggested those areas for priority funding. Since then, there has been increased investment for research on loneliness from UKRI and some of those evidence gaps have or are being filled. However, some have not been addressed and there remain important gaps to fill. In the 2018 ESRC Think Piece, the following recommendations were made: (1) the monitoring of loneliness and its drivers and consequences across the population and among specific subgroups, (2) the capturing of changes in prevalence or groups most affected by transient loneliness, with a view to understanding when and how it becomes chronic, (3) comparisons of local estimates of loneliness with national estimates, and (4) greater measurement consistency for population level surveys. In the first section of our review, we discuss the extent to which those recommendations have been endorsed, with new funding and knowledge made available

Efficacy of beta radiation in prevention of post-angioplasty restenosis

Restenosis remains a major limitation of coronary angioplasty in spite of major advances in techniques and technology. Recent studies have demonstrated that ionizing radiation may limit the degree of this problem. Gamma radiation has been shown to be effective in reducing in stent restenosis in humans, and beta radiation following encouraging results in animals has been shown to be feasible in humans. The objective of this study was to assess the feasibility of a 5 F non-centered catheter to deliver beta radiation emitting seeds to the lesion site post angioplasty and its effect on restenosis. Following successful angioplasty, patients were randomized to treatment with 12, 14 or 16 Gy at the angioplasty site. This was delivered with a 5 F non-centered catheter. Twelve beta radiation emitting seeds (90Sr/Y) were delivered to an area 3 cm in length to cover the angioplasty site. Angiographic follow-up was performed at 6 months. Baseline and follow-up angiograms were performed by blinded investigators at a core laboratory. This interim report comprises the first 35 patients to complete 6-month angiographic follow-up. There were no major radiation incidents. Four patients had evidence of angiographic restenosis. The MLD (mm) and percent stenosis were 0.77 +/- 0.27/72.5 +/- 8.6 pre angioplasty, 2.08 +/- 0.4/25.7 +/- 9.8 post angioplasty and radiation and 2.05 +/- 0.59/25.7 +/- 19.8 at follow-up respectively. CONCLUSION: Beta radiation can be feasibly and safely delivered post coronary angioplasty with a very encouraging reduction of restenosis

A Branched Kinetic Scheme Describes the Mechanochemical Coupling of Myosin Va Processivity in Response to Substrate

Myosin Va is a double-headed cargo-carrying molecular motor that moves processively along cellular actin filaments. Long processive runs are achieved through mechanical coordination between the two heads of myosin Va, which keeps their ATPase cycles out of phase, preventing both heads detaching from actin simultaneously. The biochemical kinetics underlying processivity are still uncertain. Here we attempt to define the biochemical pathways populated by myosin Va by examining the velocity, processive run-length, and individual steps of a Qdot-labeled myosin Va in various substrate conditions (i.e., changes in ATP, ADP, and Pi) under zero load in the single-molecule total internal reflection fluorescence microscopy assay. These data were used to globally constrain a branched kinetic scheme that was necessary to fit the dependences of velocity and run-length on substrate conditions. Based on this model, myosin Va can be biased along a given pathway by changes in substrate concentrations. This has uncovered states not normally sampled by the motor, and suggests that every transition involving substrate binding and release may be strain-dependent. © 2012 Biophysical Society

Variation in competent and respectful delivery care in Kenya and Malawi: a retrospective analysis of national facility surveys.

OBJECTIVE: Although substantial progress has been made in increasing access to care during childbirth, reductions in maternal and neonatal mortality have been slower. Poor-quality care may be to blame. In this study, we measure the quality of labour and delivery services in Kenya and Malawi using data from observations of deliveries and explore factors associated with levels of competent and respectful care. METHODS: We used data from nationally representative health facility assessment surveys. A total of 1100 deliveries in 392 facilities across Kenya and Malawi were observed and quality was assessed using two indices: the quality of the process of intrapartum and immediate postpartum care (QoPIIPC) index and a previously validated index of respectful maternity care. Data from standardised observations of care were analysed using descriptive statistics and multivariable random-intercept regression models to examine factors associated with variation in quality of care. We also quantified the variance in quality explained by each domain of covariates (patient-, provider- and facility-level and subnational divisions). RESULTS: Only 61-66% of basic elements of competent and respectful care were performed. In adjusted models, better-staffed facilities, private hospitals and morning deliveries were associated with higher levels of competent and respectful care. In Malawi, younger, primipara and HIV-positive women received higher-quality care. Quality also differed substantially across regions in Kenya, with a 25 percentage-point gap between Nairobi and the Coast region. Quality was also higher in higher-volume facilities and those with caesarean section capacity. Most of the explained variance in quality was due to regions in Kenya and to facility, and patient-level characteristics in Malawi. CONCLUSIONS: Our findings suggest considerable scope for improvement in quality. Increasing staffing and shifting births to higher-volume facilities - along with promotion of respectful care in these facilities - should be considered in sub-Saharan Africa to improve outcomes for mothers and newborns

MP757: Eastern Regional Potato Trials 2005: Summary of NE1014 Regional Project Field Testing of New Potato Clones

The objectives of this regional potato trial are (1) to develop pest-resistant, early-maturing, long-dormant potato varieties that will process from cold storage; (2) to evaluate new and specialty variet­ies developed in the Northeast; (3) to determine climatic effects on performance to develop pre­dictive models for potato improvement; and (4) determine heritability/linkage relationships and improve the genetic base of tetraploid cultivated varieties. The results presented in this report reflect a portion of the activity directed toward objectives 1, 2 and 3.https://digitalcommons.library.umaine.edu/aes_miscpubs/1018/thumbnail.jp