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https://digitalcommons.library.umaine.edu/mmb-me/1620/thumbnail.jp

Dim Light Exposure or Melatonin Ingestion Lowers a Type 2 Diabetic\u27s Blood Glucose Removal Rate: A Single Case

International Journal of Exercise Science 12(2): 1161-1168, 2019. The purpose of this case study isto compare a Type 2 diabetic\u27s postprandial glucoregulatory ability under two different room lighting conditions. The subject was a 56-year-old physically active male with well controlled blood glucose levels (HbA1c ≤ 6% for 5 y) from a combination of diet, exercise, and medication. Two hours post evening meal (380 kcal, 18 g fat, 44 g carbohydrate, 12 g protein), a 45 g carbohydrate challenge was given, and blood glucose was measured every 30 minutes for 2.5 hours under three conditions: dim light (\u3c50 lux) (DL), bright light (\u3e40000 lux) (BL), and bright light plus 6 mg melatonin (BLM). Each condition was repeated 3 times over a period of 6 months with each trial a minimum of seven days apart. The area under the average glucose concentration vs.time plot was different between the three conditions (BL = 909 +76; DL = 1078 +106; and BLM = 1130 +45 mmol∙min∙l-1). Visual inspection of the average blood glucose vs.time plot suggested that DL and BLM displayed very similar patterns and magnitude, with both DL and BLM having the blood glucose concentrations at each time point that are noticeably greater than BL. Additionally, the average (± standard deviation) blood glucose concentrations for DL (8.8 ± 0.9 mmol∙l-1) and BLM (9.1 ± 1.1 mmol∙l-1) were respectively 18% and 22% greater than BL (7.5 ± 0.5 mmol∙l-1). Melatonin and/or dim light can reduce a Type 2 diabetic\u27s glucoregulatory ability

Double-impulse magnetic focusing of launched cold atoms.

We have theoretically investigated three-dimensional focusing of a launched cloud of cold atoms using a pair of magnetic lens pulses (the alternate-gradient method). Individual lenses focus radially and defocus axially or vice versa. The performance of the two possible pulse sequences are compared and found to be ideal for loading both 'pancake' and 'sausage' shaped magnetic/optical microtraps. It is shown that focusing aberrations are considerably smaller for double-impulse magnetic lenses compared to single-impulse magnetic lenses. An analysis of clouds focused by the double-impulse technique is presented

Waste not, want not: CO2 (re)cycling into block polymers

A new way to combine two different polymerisation reactions, using a single catalyst, results in efficient block polymer synthesis. The selective polymerisation of mixtures of L-lactide-O-carboxyanhydride and cyclohexene oxide, using a di-zinc catalyst in a one-pot procedure, allows the preparation of poly(L-lactide-b-cyclohexene carbonate). The catalysis near quantitatively recycles the carbon dioxide released during polyester formation into the subsequent polycarbonate block, with an atom economy of up to of 91%

Modelling Esker Formation on Mars

International audience<p><strong>Introduction:</strong>  Eskers are sinuous sedimentary ridges that are widespread across formerly glaciated landscapes on Earth. They form when sediment in subglacial tunnels is deposited by meltwater. Some sinuous ridges on Mars have been identified as eskers; whilst some are thought to have formed early in Mars’ history beneath extensive ice sheets, smaller, younger systems associated with extant glaciers in Mars’ mid latitudes have also been identified. Elevated geothermal heating and formation during periods with more extensive glaciation have been suggested as possible prerequisites for recent Martian esker deposition.</p><p>Here, we adapt a model of esker formation with g and other constants altered to Martian values, using it initially to investigate the impact of Martian conditions on subglacial tunnel systems, before investigating the effect of varying water discharge on esker deposition.</p><p><strong>Methods:</strong> To investigate the effect of these values on the operation of subglacial tunnel systems we first conduct a series of model experiments with steady water discharge, varying the assumed liquid density (r<sub>w</sub>) from 1000 kgm<sup>-3</sup> to 1980 kgm<sup>-3</sup> (the density of saturated perchlorate brine) and ice hardness (A) from 2.4x10<sup>-24</sup> Pa<sup>-3</sup>s<sup>-1</sup> to 5x10<sup>-27</sup> Pa<sup>-3</sup>s<sup>-1</sup> (a temperature range of 0°C to -50°C). We then investigate the impact of variable water discharge on esker formation to simulate very simply a possible release of meltwater from an assumed geothermal event beneath a Martian glacier or ice cap.</p><p><strong>Results and Discussion:</strong>  A key aspect of model behaviour is the decrease in sediment carrying capacity towards the ice margin due to increased tunnel size as ice thins. Our results suggest that Martian parameters emphasise this effect, making deposition more likely over a greater length of the conduit. Lower gravity has the largest impact; it reduces the modeled closure rate of subglacial tunnels markedly as this varies with overburden stress (and hence g) cubed. Frictional heating from flowing water also drops, but much less sensitively. Thus, for a given discharge, the tunnels tend to be larger, leading to lower water pressure and a reduction in flow power. This effect is amplified for harder ice. Higher inferred fluid density raises the flow power, but by a smaller amount.</p><p>These effects are clearly seen in the variable discharge experiments. Sediment is deposited on the falling limb of the hydrograph, when the tunnels are larger than the equivalent steady-state water discharge would produce. Sediment deposition occurs much further upglacier from the glacier snout, and occurs earlier on the falling limb leading to longer periods in which deposition occurs.</p><p><strong>Conclusions:</strong> Our results suggest that esker formation within a subglacial meltwater tunnel would be more likely on Mars than Earth, primarily because subglacial tunnels tend to be larger for equivalent water discharges, with consequent lower water flow velocities. This allows sediment deposition over longer lengths of tunnel, and to greater depths, than for terrestrial systems. Future work will use measured bed topography of a mid-latitude esker to assess the impact of topography on deposition patterns and esker morphology, and we will expand the range of discharges and sediment supply regimes investigated.</p&gt

Possible Transport of Basal Debris to the Surface of a Mid-Latitude Glacier on Mars

International audience<p><strong>Introduction:</strong> We observe internal flow structures within a viscous flow feature (VFF; 51.24°W, 42.53°S) interpreted as a debris-covered glacier in Nereidum Montes, Mars. The structures are exposed in the wall of a gully that is incised through the VFF, parallel to its flow-direction. They are near to the glacier terminus and appear to connect its deep interior (and possibly its bed) to arcuate flow-transverse foliations on its surface. Such foliations are common on VFF surfaces, but their relation to VFF-internal structures and ice flow is poorly understood. The VFF-internal structures we observe are reminiscent of up-glacier dipping shear structures that transport basal debris to glacier surfaces on Earth.</p><p>Subglacial environments on Mars are of astrobiological interest due to the availability of water ice and shelter from Mars’ surface radiation environment. However, current limitations in drilling technology prevent their direct exploration. If debris on VFF surfaces contains a component of englacial and/or subglacial debris, those materials could be sampled without access to the subsurface. This could reduce the potential cost and complexity of future missions that aim to explore englacial and subglacial environments on Mars.</p><p><strong>Methods: </strong>We use a 1 m/pixel digital elevation model (DEM) derived from 25 cm/pixel High Resolution Imaging Science Experiment (HiRISE) stereo-pair images, and a false-colour (merged IRB) HiRISE image. We measured the dip and strike of the VFF-internal structures using ArcGIS 10.7 and QGIS software. We also input the DEM (and an inferred glacier bed topography derived from it) into ice flow simulations using the Ice Sheet System Model, assuming no basal sliding and present-day mean annual surface temperature (210K).</p><p><strong>Results and Discussion: </strong>The VFF-internal structures dip up-glacier at ~20° from the bed. This is inconsistent with their formation by bed-parallel ice-accumulation layering without modification by ice flow. The VFF-internal structures and surface foliations are spectrally ‘redder’ than adjacent VFF portions, which appear ‘bluer’. This could result from differences in debris concentration and/or surficial dust trapping between the internal structures and the bulk VFF. Modelling experiments suggest that the up-glacier-dipping structures occur at the onset of a compressional regime as ice flow slowed towards the VFF terminus.</p><p>In cold-based glaciers on Earth, up-glacier-dipping folds are common approaching zones of enhanced ice rigidity near the glacier margin. Where multiple folds co-exist, the outermost typically comprises basal ice with a component of subglacial debris entrained in the presence of interfacial films of liquid water at sub-freezing temperatures. In polythermal glaciers, debris-rich up-glacier-dipping thrust faults form where sliding wet-based ice converges with cold-based ice.</p><p><strong>Conclusions: </strong>We propose that the observed up-glacier-dipping VFF-internal structures are englacial shear zones formed by compressional ice flow. They could represent transport pathways for englacial and subglacial material to the VFF surface. The majority of extant mid-latitude VFF on Mars are thought to have been perennially cold-based; thus we favour the hypothesis that the VFF-internal structures are folds formed under a cold-based thermal regime. Under this mechanism, the outermost surface foliation, and its corresponding VFF-internal structure, is the most likely to contain subglacial debris.</p&gt

Reflections on undertaking the Probation Qualifying Framework scheme during the transforming rehabilitation changes

This article reflects upon the author’s experience of undertaking the PQF (Probation Qualifying Framework) training scheme during the chaotic period of Transforming Rehabilitation. The author asserts that the uncertainty and precarious nature of the changes were detrimental to an effective learning environment, which ultimately promoted a practice culture of punitiveness and control and did not allow learners the space to be skilful and confident practitioners, comfortable working autonomously. Furthermore, the author contends there is an emerging culture within the NPS (National Probation Service) increasingly fostered on ‘risk management’, which is reflected in the vocational nature of PQF training and is contributing towards a widening cultural gap that is emerging between the community rehabilitation companies and NPS

Internal Structure of a Glacier on Mars Revealed by Gully Incision

International audienceDebris transport from / A Mars glacier bed to / Flowlines on surface