Temporal Variability of Phosphorus Concentration in the Stream to Squam Lake, New Hampshire During Storm Events

Phosphorus (P) enrichment to most rivers and lakes degrades the water quality, particularly by stimulating the growth of aquatic plants and algae. To determine the relative importance of precipitation events to the nutrient inputs to lakes, P input was estimated at Livermore Cove Brook, tributary of Squam Lake, NH during 3 storm events in summer 2016. Water samples were collected hourly during the events using ISCO samplers and analyzed for specific conductivity, turbidity, total P (TP), total dissolved P (TDP), total particulate P (TPP), soluble reactive P (SRP), dissolved organic P (DOP) and deuterium isotope (2H). 2H was used in two-component mixing analysis to calculate the % of new-water as a proxy for direct runoff. TP concentrations peaked with stream flow (up to 453.7 ppb) with much higher concentration in rising limb than on falling limb resulted in clockwise hysteresis. We believe this is due to the changing contribution of different water sources to the streams and variable mobility of sediment P during runoff. The SRP was minor component during event but was more significant during baseflow periods. We also found that DOP was most dominant form of P except during strong runoff periods where TPP was an important component

Morpho-physiological and biochemical response of rice (Oryza sativa L.) to drought stress: A review

Global food shortages are caused mainly by drought, the primary driver of yield loss in agriculture worldwide. Drought stress negatively impacts the physiological and morphological characteristics of rice (Oryza sativa L.), limiting the plant productivity and hence the economy of global rice production. Physiological changes due to drought stress in rice include constrained cell division and elongation, stomatal closure, loss of turgor adjustment, reduced photosynthesis, and lower yields. Morphological changes include inhibition of seed germination, reduced tillers, early maturity, and reduced biomass. In addition, drought stress leads to a metabolic alteration by increasing the buildup of reactive oxygen species, reactive stress metabolites, antioxidative enzymes, and abscisic acid. Rice tends to combat drought through three major phenomena; tolerance, avoidance, and escape. Several mitigation techniques are introduced and adapted to combat drought stress which includes choosing drought-tolerant cultivars, planting early types, maintaining adequate moisture levels, conventional breeding, molecular maintenance, and creating variants with high-yielding characteristics. This review attempts to evaluate the various morpho-physiological responses of the rice plant to drought, along with drought stress reduction techniques

Bark Extract of Lantana camara in 1M HCl as Green Corrosion Inhibitor for Mild Steel

Lantana camara, an invasive species that adversely affects habitant, bioregions and environment has been studied as corrosion inhibitor. Methanolic extract of barks of Lantana camara in 1 M hydrochloric acid was tested as corrosion inhibitor on mild steel using potentiodynamic polarization technique. The corrosion inhibition efficiency of extract varied with concentration of extract and immersion of time. The inhibition was found to increase with increase in concentration of the extract. The polarization behavior of mild steel revealed that maximum inhibition efficiency is 97.33 % and 89.93 % respectively in the 1000 and 200 ppm concentration of the inhibitor respectively. The results showed that the extract of the barks of Lantana camara served as a mixed type inhibitor

Autologous blood products : Leucocyte and Platelets Rich Fibrin (L-PRF) and Platelets Rich Plasma (PRP) gel to promote cutaneous ulcer healing – a systematic review

Objective To summarise evidence on the effectiveness of Platelet-Rich Plasma (PRP) gel and Leucocyte and Platelet Rich Fibrin (L-PRF) gel as agents promoting ulcer healing compared with the standard wound dressing techniques alone. Design Systematic review. Eligibility criteria Individual patient randomised controlled trials on skin ulcers of all types excluding traumatic lesions. Intervention group: treatment with topical application of L-PRF gel or PRP gel to the wound surface. Control group: treatment with standard skin ulcer care using normal saline, normgel or hydrogel dressings. Information sources Medline (Ovid), Excerpta Medica Database (EMBASE), Scopus, Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Web of Science and manual search of studies from previous systematic reviews and meta-analyses. The papers published from 1946 to 2022 with no restriction on geography and language were included. The last date of the search was performed on 29 August 2022. Data extraction and synthesis Independent reviewers identified eligible studies, extracted data, assessed risk of bias using V.2 of the Cochrane risk-of-bias tool for randomised trials tool and assessed certainty of evidence by using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. Main outcome measures Time to complete healing, proportion healed at a given time and rate of healing. Results Seven studies met the inclusion criteria, five using PRP gel and two using L-PRF gel. One study showed a better proportion of complete healing, three reported reduced meantime to complete healing and five showed improved rate of healing per unit of time in the intervention group. The risk of bias was high across all studies with one exception and the GRADE showed very low certainty of evidence. Conclusion The findings show potential for better outcomes in the intervention; however, the evidence remains inconclusive highlighting a large research gap in ulcer treatment and warrant better-designed clinical trial

A randomised Trial of Autologous Blood products, leukocyte and platelet-rich fibrin (L-PRF), to promote ulcer healing in LEprosy : The TABLE trial

Introduction: Autologous blood products like Platelet Rich Plasma (PRP) and Leukocyte and Platelets Rich Fibrin (L-PRF) have been used for many years across many types of skin ulcers. However, the effectiveness of autologous blood products on wound healing is not well established. Methods: We evaluated the ‘second generation’ autologous product- Leukocyte and Platelet- Rich Fibrin (L-PRF). Our trial was undertaken on patients suffering from neuropathic leprosy ulcers at the Anandaban hospital which serves the entire country of Nepal. We conducted a 1:1 (n = 130) individually randomised trial of L-PRF (intervention) vs. normal saline dressing (control) to compare rate of healing and time to complete healing. Rate of healing was estimated using blind assessments of ulcer areas based on three different measurement methods. Time to complete healing was measured by the local unblinded clinicians and by blind assessment of ulcer images. Results: The point estimates for both outcomes were favourable to L-PRF but the effect sizes were small. Unadjusted mean differences (intervention vs control) in mean daily healing rates (cm2) were respectively 0.012 (95% confidence interval 0.001 to 0.023, p = 0.027); 0.016 (0.004 to 0.027, p = 0.008) and 0.005 (-0.005 to 0.016, p = 0.313) across the three measurement methods. Time to complete healing at 42 days yielded Hazard Ratios (unadjusted) of 1.3 (0.8 to 2.1, p = 0.300) assessed by unblinded local clinicians and 1.2 (0.7 to 2.0, p = 0.462) on blind assessment. Conclusion: Any benefit from L-PRF appears insufficient to justify routine use in care of neuropathic ulcers in leprosy. Trial registration: ISRCTN14933421. Date of trial registration: 16 June 2020

Congenital microcephaly: Case definition & guidelines for data collection, analysis, and presentation of safety data after maternal immunisation.

Need for developing case definitions and guidelines for data collection, analysis, and presentation for congenital microcephaly as an adverse event following maternal immunisation Congenital microcephaly, also referred to as primary microcephaly due to its presence in utero or at birth, is a descriptive term for a structural defect in which a fetus or infant’s head (cranium) circumference is smaller than expected when compared to other fetuses or infants of the same gestational age, sex and ethnic background