Working to Improve Human Papilloma Virus Vaccination Uptake in Michigan

Increased cases of Human Papillomavirus (HPV) related cancers and low HPV vaccine uptake are public health concerns that directly affect young adults and adolescents around the country. The HPV vaccine is recommended to prevent HPV associated cancers. Increased awareness and health education interventions are needed to promote the importance of the HPV vaccine and to achieve an HPV vaccine completion rate of 80% as outlined by the Healthy People 2020 goal. The Michigan Cancer Consortium HPV vaccine Priority Workgroup is working to improve vaccine uptake in Michigan through statewide projects that promote health education resources and address barriers associated with low HPV vaccine uptake

Impact of the Resident Microbiota on the Nutritional Phenotype of Drosophila melanogaster

Background: Animals are chronically infected by benign and beneficial microorganisms that generally promote animal health through their effects on the nutrition, immune function and other physiological systems of the host. Insight into the host-microbial interactions can be obtained by comparing the traits of animals experimentally deprived of their microbiota and untreated animals. Drosophila melanogaster is an experimentally tractable system to study host-microbial interactions. Methodology/Principal Findings: The nutritional significance of the microbiota was investigated in D. melanogaster bearing unmanipulated microbiota, demonstrated by 454 sequencing of 16S rRNA amplicons to be dominated by the a-proteobacterium Acetobacter, and experimentally deprived of the microbiota by egg dechorionation (conventional and axenic flies, respectively). In axenic flies, larval development rate was depressed with no effect on adult size relative to conventional flies, indicating that the microbiota promotes larval growth rates. Female fecundity did not differ significantly between conventional and axenic flies, but axenic flies had significantly reduced metabolic rate and altered carbohydrate allocation, including elevated glucose levels. Conclusions/Significance: We have shown that elimination of the resident microbiota extends larval development and perturbs energy homeostasis and carbohydrate allocation patterns of of D. melanogaster. Our results indicate that th

APPLYING SIGNAL-DETECTION THEORY TO THE STUDY OF OBSERVER ACCURACY AND BIAS IN BEHAVIORAL ASSESSMENT

We evaluated the feasibility and utility of a laboratory model for examining observer accuracy within the framework of signal-detection theory (SDT). Sixty-one individuals collected data on aggression while viewing videotaped segments of simulated teacher–child interactions. The purpose of Experiment 1 was to determine if brief feedback and contingencies for scoring accurately would bias responding reliably. Experiment 2 focused on one variable (specificity of the operational definition) that we hypothesized might decrease the likelihood of bias. The effects of social consequences and information about expected behavior change were examined in Experiment 3. Results indicated that feedback and contingencies reliably biased responding and that the clarity of the definition only moderately affected this outcome