4,319 research outputs found
Understanding Society: design overview
Understanding Society, the UK Household Longitudinal Study, builds on the success of the British Household Panel Survey (BHPS). This paper describes some of the key elements of the design and conduct of the study and suggests how Understanding Society is distinctive as a longitudinal survey. Its large sample size offers new opportunities to study sub-groups that may be too small for separate analysis on other studies. The new content included in Understanding Society, not least the bio-measures, provides exciting prospects for interdisciplinary research across the social and medical sciences. The Innovation Panel is already proving to be an invaluable resource for research in longitudinal survey methodology. Finally, the inclusion of the BHPS sample within Understanding Society enables this long running panel to continue into the future, opening up inter-generational research and the opportunity to look at very long-term trajectories of change. This paper also describes the four sample components: the general population sample, ethnic minority boost sample, the Innovation Panel, and participants from the BHPS. Each component has a multistage sample designs, mostly with stratification and clustering. A complex weighting strategy is being developed to support varied analyses. This overview also describes the instruments, methods of data collection, and the timetable for data collection. A summary of the survey content?s is provided. With the data becoming available the user community is beginning to benefit from this investment in longitudinal studies
DYNAMICS OF FOOD PRICE INFLATION
A supply-shift concept of food price inflation is offered as an explanation of why food prices have increased in recent years. This view is consistent with cost-push theories of inflation. The effects of higher farm product prices on food prices are analyzed using Pascal distributed lag models of the price adjustment process. Estimates are presented for 23 selected food products. The results indicate that higher farm prices are passed through to the retail level most quickly for food products which are not highly processed.Demand and Price Analysis,
DEMAND AND SUPPLY OF VEGETABLE OIL PRODUCTS IN THE UNITED STATES: A SHORT-RUN ANALYSIS
Demand and Price Analysis,
ESTIMATING MARKETING MARGIN COST COMPONENTS: AN APPLICATION OF SIMULATION TO PRODUCTS OF THE VEGETABLE OIL INDUSTRY
Demand and Price Analysis,
Mixing and transport by ciliary carpets: a numerical study
We use a 3D computational model to study the fluid transport and mixing due
to the beating of an infinite array of cilia. In accord with recent
experiments, we observe two distinct regions: a fluid transport region above
the cilia and a fluid mixing region below the cilia tip. The metachronal wave
due to phase differences between neighboring cilia is known to enhance the
fluid transport above the ciliary tip. In this work, we show that the
metachronal wave also enhances the mixing rates in the sub-ciliary region,
often simultaneously with the flow rate enhancement. Our results suggest that
this simultaneous enhancement in transport and mixing is due to an enhancement
in shear flow. As the flow above the cilia increases, shear rate in the fluid
increases and such shear enhances stretching, which is an essential ingredient
for mixing. Estimates of the mixing time scale indicate that, compared to
diffusion, the mixing due to the cilia beat may be significant and sometimes
dominates chemical diffusion.Comment: submitted to Journal of Fluid Mechanic
Das Lizzie-Lied: The Lizzie Song
To hear the music go to http://quizzes.denison.edu/modlangs/podcasts/shaun.mp
Mechanisms Of Hormonal Regulation Of Invasiveness And Metastasis Of Luminal Breast Cancer
ABSTRACT
MECHANISMS OF HORMONAL REGULATION OF INVASIVENESS AND METASTASIS OF LUMINAL BREAST CANCER
By
THOMAS MCFALL
December 2017
Advisor: Dr. Manohar Ratnam
Major: Cancer Biology
Degree: Doctor of Philosophy
Over 20% of breast cancer cases present with distal metastasis and they are predominantly of luminal subtypes. As luminal breast cancer is relatively indolent, it is believed that progression to metastasis must occur over many years, generally well into post-menopausal years. Unfortunately, very little is known about the mechanisms by which these hormone receptor positive tumors metastasize, likely in part due to their slow metastatic rates in animal model systems as well. Moreover, the literature lacks adequate mechanistic understanding of cross talk between estradiol (E2) and progesterone, particularly in the context of breast cancer invasion and metastasis. In this thesis, we sought to investigate the roles of estrogen and progesterone and their nuclear receptors to better understand hormonal regulation of metastasis at physiologically relevant hormone levels both pre- and post-menopause. The novelty of our experimental approach and study design is three-fold: 1. exploration of the isoform-specific actions of the progesterone receptor; 2. investigation of selective micro RNA mediated pathways of cross talk between estrogen and progesterone and 3. development of a quantitative lymph node infiltration assay to monitor metastasis of luminal breast cancer in xenograft models
Why American Parents Choose Homeschooling
This study explored factors that impact parents’ decisions to homeschool their children and examined the relationship between selected demographic factors and families that homeschool using an online survey snowball sample. Past research has focused on four main constructs: religious reasons, school safety, academic instruction, and a child’s special needs. This study elaborated on these four constructs and expanded to include other reasons parents might homeschool such as a need for family time, family travel, distance to school, financial reasons, or wanting to take a nontraditional approach to student learning. Findings suggest that academic instruction, family time and the desire to take a nontraditional approach to education are the reasons that parents homeschool. Demographically the homeschool population has not changed since the landmark 1999 Rudner study. However, the reasons that parents choose to homeschool have shifted to reflect the current state of unrest education in the United States
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