Pollination ecology of Agave palmeri in New Mexico, and landscape use of Leptonycteris nivalis in relation to Agaves

Where animals spend time can provide important clues to their ecological needs, but this information is very difficult to obtain for small volant animals. The research described in Chapter 1 was an attempt to discern how L. nivalis utilize the landscape in relation to the distribution of Agave havardiana in Big Bend National Park, Texas. I found that although the landscape use of Leptonycteris nivalis is centered on habitat with high concentrations of blooming A.havardiana, it is not restricted to those areas, and furthermore adults and juveniles may differ in their behavior. Adult females may remain near food sources in order to replenish energy stores lost to migration and the demands of reproduction, whereas juveniles may feed early in the evening and then undertake occasional far-reaching expeditions, perhaps in order to create a navigational map. If this behavior is widespread among juveniles, it emphasizes the need to carefully assess the risk of constructing wind-turbine energy facilities not just within agave-rich habitat, but anywhere near the range of this endangered bat species. The research described in Chapter 2 focused on documenting the importance of flowering agaves as a food resource for the many vertebrate and invertebrate, diurnal and nocturnal visitors. I found that A. palmeri was visited by a wide variety of vertebrate and invertebrate visitors, many of which are pollinators of other plants, and that there was considerable variation in visitation rates in space and time - in fact, bats were not even observed at one of the study sites. Increased visitation was associated with larger plant sizes for all visitor types assessed. In Chapter 3, I explored how the fruit and seed production of A. palmeri at these three sites were affected by the plants morphology, phenology (timing of bloom), prior reproductive success, and the patterns of visitation by different animal guilds. Models indicated that bats were the most effective visitors, because periods with high bat visitation rates also had very high seed. Periods with high bird visitation resulted in many fruits but with poor seed set, possibly indicating that they are responsible for some degree of reproduction, though the exact mechanism is not clear. Floral branch position interacted in a complex manner with prior fruit set, affecting fruit set, seed set, and mean seed mass. Plants with high prior fruit set showed decreased seed set in fruits on late-blooming branches, possibly indicative of resource limitation

Physical and biological controls on fine sediment transport and storage in rivers

Excess fine sediment, comprising particles <2 mm in diameter, is a major cause of ecological degradation in rivers. The erosion of fine sediment from terrestrial or aquatic sources, its delivery to the river, and its storage and transport in the fluvial environment are controlled by a complex interplay of physical, biological and anthropogenic factors. Whilst the physical controls exerted on fine sediment dynamics are relatively well-documented, the role of biological processes and their interactions with hydraulic and physico-chemical phenomena has been largely overlooked. The activities of biota, from primary producers to predators, exert strong controls on fine sediment deposition, infiltration and resuspension. For example, extracellular polymeric substances (EPS) associated with biofilms increase deposition and decrease resuspension. In lower energy rivers, aquatic macrophyte growth and senescence are intimately linked to sediment retention and loss, whereas riparian trees are dominant ecosystem engineers in high energy systems. Fish and invertebrates also have profound effects on fine sediment dynamics through activities that drive both particle deposition and erosion depending on species composition and abiotic conditions. The functional traits of species present will determine not only these biotic effects but also the responses of river ecosystems to excess fine sediment. We discuss which traits are involved and put them into context with spatial processes that occur throughout the river network. Whilst strides towards better understanding of the impacts of excess fine sediment have been made, further progress to identify the most effective management approaches is urgently required through close communication between authorities and scientists

Patterns of extrapulmonary metastases in sarcoma surveillance

Soft tissue sarcomas (STS) most commonly metastasize to the lungs. Current surveillance guidelines variably recommend abdominal and pelvic imaging, but there is little evidence to support this. We sought to determine the proportion of initial pulmonary versus extrapulmonary metastases, the time to development of each, and factors to identify patients that would benefit from abdominopelvic surveillance. We retrospectively reviewed 382 patients who underwent surgical treatment for STS at a single institution. Of the 33% (126/382) of patients who developed metastases, 72% (90/126) were pulmonary, 22% (28/126) were extrapulmonary, and 6% (8/126) developed both simultaneously. Initial extrapulmonary metastases occurred later (log ran

Economic Conditions And How It Effects Trade Between The U.S. And India

This paper examines the economic conditions that effect trade between the U.S. and India. Examining the existing economic conditions of both countries is important to determine the current and future trade issues that both countries may face. Since India’s formation in 1947 and up until 1991, India was a closed economy with strict controls and regulations regarding trade. After a severe economic crisis in 1991 India started opening its borders to foreign trade, embraced globalization and drastically liberalized its trade policy.  However, the exploding population in India is having strong economic and environmental implications for India and how it relates to the rest of the world.

Service user engagement in healthcare education as a mechanism for value based recruitment: An evaluation study

Within the United Kingdom (UK) there is an increasing focus on Values Based Recruitment (VBR) of staff working in the National Health Service (NHS) in response to public inquiries criticising the lack of person-centred care. All NHS employees are recruited on the basis of a prescribed set of values. This is extended to the recruitment of student healthcare professionals, yet there is little research of how to implement this. Involving Service Users in healthcare educational practice is gaining momentum internationally, yet involvement of service users in VBR of ‘would be’ healthcare professionals remains at an embryonic phase. Adult nurses represent the largest healthcare workforce in the UK, yet involvement of service users in their recruitment has received scant attention. This paper is an evaluation of the inclusion of service users in a VBR of 640 adult student nurses

Comparing Communication Doctoral Programs, Alumni, and Faculty: The Use of Google Scholar

This paper examines three aspects of doctoral programs in Communication: (a) how doctoral department faculty compare using combined citations to published work using Google Scholar, (b) the contribution in quantity and quality (measured by citations) of alumni teaching in doctoral programs, and (c) identifying the top 25 most cited communication doctoral faculty in Google Scholar. The goal is to provide a series of additional alternatives for faculty and program evaluation beyond simply counting the number of published journal articles

Integration of kinase and calcium signaling at the level of chromatin underlies inducible gene activation in T cells

TCR signaling pathways cooperate to activate the inducible transcription factors NF-κB, NFAT, and AP-1. In this study, using the calcium ionophore ionomycin and/or PMA on Jurkat T cells, we show that the gene expression program associated with activation of TCR signaling is closely related to specific chromatin landscapes. We find that calcium and kinase signaling cooperate to induce chromatin remodeling at ∼2100 chromatin regions, which demonstrate enriched binding motifs for inducible factors and correlate with target gene expression. We found that these regions typically function as inducible enhancers. Many of these elements contain composite NFAT/AP-1 sites, which typically support cooperative binding, thus further reinforcing the need for cooperation between calcium and kinase signaling in the activation of genes in T cells. In contrast, treatment with PMA or ionomycin alone induces chromatin remodeling at far fewer regions (∼600 and ∼350, respectively), which mostly represent a subset of those induced by costimulation. This suggests that the integration of TCR signaling largely occurs at the level of chromatin, which we propose plays a crucial role in regulating T cell activation

Screening for asthma in Cantonese-speaking immigrant children

BACKGROUND: Asthma prevalence among Chinese immigrant children is poorly understood and attempts to screen these children have produced varied outcomes. We sought to learn how to improve screening for asthma in Chinese immigrant children. METHODS: Children (n = 152) were administered the Brief Pediatric Asthma Screen in either Cantonese or English, they then viewed and reacted to a video showing people wheezing and subsequently took a pulmonary function test. RESULTS: The diagnosed asthma prevalence for our study population was 27.0%, with another 5.3% having possible undiagnosed asthma. Very few children had spirometry findings below normal. In multivariate analysis, being native born (p = 0.002) and having a family history of asthma (p = 0.003) were statistically associated with diagnosis of asthma. After viewing the video, 35.6% of respondents indicated that the images differed from their conception of wheezing. Of four translations of the word "wheeze" no single word was chosen by a majority. CONCLUSION: Our findings suggest that asthma diagnoses are higher for Chinese children who were born in the US suggesting that desegregation of data might reveal at risk subpopulations. Care needs to be taken when diagnosing asthma for Cantonese speakers because of the centrality of the word wheeze and the challenges of translation

A longitudinal study of well-being, confidence and competence in junior doctors and the impact of emergency medicine placements.

OBJECTIVES: To measure levels of, and change in junior doctor well-being, confidence and self-reported competence over their second postgraduate training year and the impact of emergency department (ED) placements on these outcomes. DESIGN: A longitudinal study using an online survey administered at four time points (2010-2011). SETTING: 28 Acute Hospital Trusts, drawn from nine participating Postgraduate Deaneries in England. PARTICIPANTS: Junior doctors who had a placement in an ED as part of their second postgraduate training year. MAIN OUTCOME MEASURES: Levels of anxiety, depression, motivation, job satisfaction, confidence and self-reported competence, collected at four time points spread over the period of the doctor's second training year (F2). RESULTS: 217 junior doctors were recruited to the study. Over the year there was a significant increase in their overall job satisfaction, confidence and self-reported competence. Junior doctors also reported significantly increased levels of motivation and anxiety, and significantly decreased levels of extrinsic job satisfaction when working in ED compared with other specialties. There were also significant increases in both junior doctor confidence and self-reported competence after their placement in ED relative to other specialties. CONCLUSIONS: While elements of junior doctor well-being worsened in their ED placement compared with their time spent in other specialties, the increased levels of anxiety and reduced extrinsic job satisfaction were within the normal range for other healthcare workers. These deficits were also balanced by greater improvements in motivation, confidence in managing common acute clinical conditions and perceived competence in performing acute procedures compared with benefits offered by placements in other specialties

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy