Disqvisitio theologica: quod S. Coena non sit sacramentvm praeparationis: breuiter & modeste expendens, contra celeberr. doct. Christoph. Matth. Pfaffium. Quam consensu ven. facult. theol. in Reg. Acad. Ab. sub praesidio doct. Andreae Bergii, s. theol. prof. primar. & archipraepos. Ab. Publico examini submittit avctor Matthias Hallenivs ibidem mag. docens & v. lect. sch. cath. d. III. Decembr. M.DCC.XXXVII. In auditorio maximo horis ante meridiem consuetis

Dedicatio: Ernestus Johannes Creutz, Jonas Fahlenius, Samuel Blomfelt, Adamus Fredenstierna, Johannes Arckenholtz.Arkit: 3 arkintunnuksetonta lehteä, A-B4 [C2].Painovuosi nimekkeestä

Discursus physiologico-logicus, de operationibus intellectus humani, quem consensu amplis. facult. philos. in Reg. ad Auram Acad. sub praesidio viri amplissimi dn. Andreae Pryss, poeseos professoris reg. & ord. Pro gradu magisterii publ. cand. phil. examini modeste submittit alumnus regius. Iohannes Fortelius Biörneburgensis. Die Deo volente 17. Junii an. MDCCXXIX. loco horisque solitis.

Variantti B.Invokaatio: Ductore Jehovah!Gratulaatio: Jean H. Svahn, Martin Svahn, Nicolaus Idman.Painovuosi nimekkeestä.Arkit: 1 arkintunnukseton lehti, A-D4. - S. [2] tyhjä.Ensimmäinen gratulaatio on ruotsinkielinen. Toinen gratulaatio on ranskankielinen

Network coordination following discharge from psychiatric inpatient treatment : a study protocol

Background: Inadequate discharge planning following inpatient stays is a major issue in the provision of a high standard of care for patients who receive psychiatric treatment. Studies have shown that half of patients who had no pre-discharge contact with outpatient services do not keep their first outpatient appointment. Additionally, discharged patients who are not well linked to their outpatient care networks are at twice the risk of re-hospitalization. The aim of this study is to investigate if the Post-Discharge Network Coordination Program at ipw has a demonstrably significant impact on the frequency and duration of patient re-hospitalization. Subjects are randomly assigned to either the treatment group or to the control group. The treatment group participates in the Post-Discharge Network Coordination Program. The control group receives treatment as usual with no additional social support. Further outcome variables include: social support, change in psychiatric symptoms, quality of life, and independence in daily functioning. Methods/design: The study is conducted as a randomized controlled trial. Subjects are randomly assigned to either the control group or to the treatment group. Computer generated block randomization is used to assure both groups have the same number of subjects. Stratified block randomization is used for the psychiatric diagnosis of ICD-10, F1. Approximately 160 patients are recruited in two care units at Psychiatrie-Zentrum Hard Embrach and two care units at Klinik Schlosstal Winterthur. Discussion: The proposed post-discharge network coordination program intervenes during the critical post-discharge period. It focuses primarily on promoting the integration of the patients into their social networks, and additionally to coordinating outpatient care and addressing concerns of daily life

The brief symptom inventory and the outcome questionnaire-45 in the assessment of the outcome quality of mental health interventions

Self-report questionnaires are economical instruments for routine outcome assessment. In this study, the performance of the German version of the Outcome Questionnaire-45 (OQ-45) and the Brief Symptom Inventory (BSI) was evaluated when applied in analysis of the outcome quality of psychiatric and psychotherapeutic interventions. Pre-post data from two inpatient samples (N = 5711) and one outpatient sample (N = 239) were analyzed. Critical differences (reliable change index) and cut-off points between functional and dysfunctional populations were calculated using the Jacobson and Truax method of calculating clinical significance. Overall, the results indicated that the BSI was more accurate than the OQ-45 in correctly classifying patients as clinical subjects. Nonetheless, even with the BSI, about 25% of inpatients with schizophrenia attained a score at admission below the clinical cut-off. Both questionnaires exhibited the highest sensitivity to psychopathology with patients with personality disorders. When considering the differences in the pre-scores, both questionnaires showed the same sensitivity to change. The advantage of using these self-report measures is observed primarily in assessing outpatient psychotherapy outcome. In an inpatient setting two main problems-namely, the low response rate and the scarce sensitivity to psychopathology with severely ill patients-limit the usability of self-report questionnaires

Factors influencing patients’ recovery and the efficacy of a psychosocial post-discharge intervention : post hoc analysis of a randomized controlled trial

Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)Purpose: The aim of this post hoc analysis was to examine self-reported recovery following a post-discharge intervention and to focus on the moderators of this intervention programme. Methods: RCT using parallel group block randomisation, including 151 patients with ≤3 hospitalisations within the last 3 years, a GAF score ≤60, and aged 18–64 years, assessed at two psychiatric hospitals from Zurich, Switzerland, between September 2011 and February 2014. In the present study, the main outcome was the OQ-45 as assessed prior to discharge from the index hospitalisation and at 12-month follow-up. Participants received either the post-discharge intervention provided by a social worker or treatment as usual (TAU). Results: Patients in the intervention group showed substantially less recovery over the 12-month observation period than controls (d = 0.44). In the TAU group, 15.6 % remained clinically impaired at 12-month follow-up as opposed to 48.1 % in the intervention group (p = 0.001). Among participants in the intervention group, an interdisciplinary meeting of significant network members was associated with less recovery (d = 0.46). Involuntary index admission (d = 0.42) and high educational degree (d = 0.52) were significant moderators of the intervention. Both factors related to less recovery over time in the intervention group relative to TAU. Conclusions: According to the OQ-45, this psychosocial post-discharge intervention revealed an unintended negative effect on self-reported recovery over time. Specifically, the meeting of significant network members related to a moderate deteriorating effect, suggesting that the involvement of some carers, relatives, or friends may cause harm to the patient. Considering with reservation pending replication, these findings could have important implications for brief interventions targeted at patients’ social networks

Relaxed eddy accumulation measurements of the sea-to-air transfer of dimethylsulfide over the northeastern Pacific

Author Posting. © American Geophysical Union, 2004. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution. The definitive version was published in Journal of Geophysical Research 109 (2004): C01025, doi:10.1029/2002JC001616.Gas transfer rates were determined from relaxed eddy accumulation (REA) measurements of the flux of dimethylsulfide (DMS) over the northeastern Pacific Ocean. This first application of the REA technique for the measurement of DMS fluxes over the open ocean produced estimates of the gas transfer rate that are on average higher than those calculated from commonly used parameterizations. The relationship between the total gas transfer rate and wind speed was found to be gas kgas = 0.53 (±0.05) U102. Because of the effect of the airside resistance, the waterside transfer rate was up to 16% higher than kgas. Removal of the airside transfer component from the total transfer rate resulted in a relation between wind speed and waterside transfer of k660 = 0.61 (±0.06) U102. However, DMS fluxes showed a high degree of scatter that could not readily be accounted for by wind speed and atmospheric stability. It has to be concluded that these measurements do not permit an accurate parameterization of gas transfer as a function of wind speed.Funding for this work came from the Netherlands Organization for Scientific Research (NWO) and from the NOP project: ‘Micrometeorology of air/sea fluxes of carbon dioxide’ No. 951203. This work was also supported in part by the Office of Naval Research Grant No. N00014-00-1-0403, NOAA CICOR Grant No. NA87RJ0445, and the U.S. National Science Foundation Grant ATM- 0120569

Antidepressant Use During Acute Inpatient Care Is Associated With an Increased Risk of Psychiatric Rehospitalisation Over a 12-Month Follow-Up After Discharge

Background: Some evidence suggests that antidepressants may relate to poor outcomes in depression. The aim of this study was, therefore, to examine, whether antidepressant use may worsen the long-term outcome in real-world psychiatric patients with both primarily affective and non-affective mental disorders.Methods: Based on a total of n = 151 inpatients with a mixed range of diagnoses enrolled at two psychiatric hospitals in Zurich, Switzerland, matched pairs of n = 45 antidepressant users and n = 45 non-users were selected via nearest neighbor propensity score matching. Pairs were matched according to 14 clinically relevant covariates assessing psychosocial impairments, functioning deficits and illness severity. The two outcomes of interest were the number and total duration of all rehospitalisations over a 12-month follow-up after discharge from the hospital based on the official clinical registry.Results: Altogether 35.6% of antidepressant users were rehospitalised at least once, as compared to 22.2% in matched non-users. Two or more rehospitalisations occurred in 22.2% of antidepressant users but only in 2.2% of non-users. In antidepressant users, the mean total duration of rehospitalisations was 22.22 days, as compared to 8.51 in matched non-users. According to Poisson regression analyses, antidepressant use during acute inpatient care prospectively relates to both a higher risk (incidence rate ratio [IRR] = 3.64, 95% confidence interval [95%-CI] = 1.71–7.75, p = 0.001) and a longer duration (IRR = 2.61, 95%-CI = 1.01–6.79, p = 0.049) of subsequent rehospitalisations. These findings were consistently replicated when traditional multivariable regression analysis was applied to the full sample. Findings also replicated when patients with affective and non-affective disorders were analyzed separately.Conclusions: Our findings raise the possibility that, in the long-term, antidepressants may impair recovery and increase the risk of rehospitalisation in patients with both primarily affective and non-affective disorders. More work is required to explore possible aetiopathological pathways leading to psychiatric rehospitalisation

Surface ocean iron fertilization: the role of subduction zone and hotspot volcanic ash and fluxes into the Pacific Ocean

Surface ocean iron (Fe) fertilization can affect the marine primary productivity (MPP), thereby impacting on CO2 exchanges at the atmosphere-ocean interface and eventually on climate. Mineral (aeolian or desert) dust is known to be a major atmospheric source for the surface ocean biogeochemical iron cycle, but the significance of volcanic ash is poorly constrained. We present the results of geochemical experiments aimed at determining the rapid release of Fe upon contact of pristine volcanic ash with seawater, mimicking their dry deposition into the surface ocean. Our data show that volcanic ash from both subduction zone and hot spot volcanoes (n = 44 samples) rapidly mobilized significant amounts of soluble Fe into seawater (35–340 nmol/g ash), with a suggested global mean of 200 ± 50 nmol Fe/g ash. These values are comparable to the range for desert dust in experiments at seawater pH (10–125 nmol Fe/g dust) presented in the literature (Guieu et al., 1996; Spokes et al., 1996). Combining our new Fe release data with the calculated ash flux from a selected major eruption into the ocean as a case study demonstrates that single volcanic eruptions have the potential to significantly increase the surface ocean Fe concentration within an ash fallout area. We also constrain the long-term (millennial-scale) airborne volcanic ash and mineral dust Fe flux into the Pacific Ocean by merging the Fe release data with geological flux estimates. These show that the input of volcanic ash into the Pacific Ocean (128–221 × 1015 g/ka) is within the same order of magnitude as the mineral dust input (39–519 × 1015 g/ka) (Mahowald et al., 2005). From the similarity in both Fe release and particle flux follows that the flux of soluble Fe related to the dry deposition of volcanic ash (3–75 × 109 mol/ka) is comparable to that of mineral dust (1–65 × 109 mol/ka). Our study therefore suggests that airborne volcanic ash is an important but hitherto underestimated atmospheric source for the Pacific surface ocean biogeochemical iron cycle