Modelo agrícola e impacto socioambiental en la Argentina: monocultivo y agronegocios

Este trabajo está animado por el hecho de disentir con todas aquellas interpretaciones aferradas al paradigma epistemológico positivista, que niega el reconocimiento de la intencionalidad, la autoreflexividad, la creación y la pasión que acompañan a toda producción de conocimiento. En consonancia con ello, nos permitimos destacar la interdisciplinaridad de la propuesta, que conjuga nuestros avances en la investigación en el campo de las Ciencias Médicas, la Ecología y la Antropología Social, contemplando y fortaleciendo la necesidad de pensar en términos de la diversidad sociocultural que poseen las poblaciones afectadas por el modelo agrícola, en particular por la explotación sojera, así como la desigualdad estructural que las atraviesa y las condiciona. Las investigaciones se caracterizan por reconocer que lo que nos sucede y nos preocupa, respecto de nuestra sociedad y de la humanidad en su conjunto, puede y debe ser pensado superando la noción de un hombre estándar que no existe más que en la ficción (Foucault, 1966), la de un hombre en sentido genérico, superando al mismo tiempo la noción de pensamiento único.Asociación de Universidades Grupo Montevideo (AUGM

Mesoscale eddy variability in the Caribbean Sea

The spatial distribution, and the monthly and seasonal variability of mesoscale eddy observations derived from the AVISO eddy atlas are assessed in the Caribbean Sea during 1993–2019. The average lifetime for the whole set of eddies is 62 ± 37 days, mean amplitude of 7 ± 4 cm for cyclonic and 7 ± 4 cm for anticyclonic and mean radius of 100 ± 31 km for cyclonic and 108 ± 32 km for anticyclonic. Cyclonic eddies are on average more nonlinear than anticyclonic ones. The spatio-temporal variability in the number of eddy observations is evaluated against the Mean Eddy Kinetic Energy (MEKE) derived from geostrophic currents as well as from seasonal winds. Spatial distribution of eddy observations is correlated with MEKE while the migration of the intertropical convergence zone explains the advection of eddies towards the southern part of the basin.Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. JMS received the joint funding from the Generalitat Valenciana and the European Social Fund under Grant APOSTD/2020/254. AO received financial support from projects Mocca and Lamarca (grants # RTI2018-093941-B-C31 and PID2021-123352OB-C31) funded by MCIN/AEI/ and by “ERDF A way of making Europe”, and from Fundación Iberostar and Université de Toulon-VAR. MELA is funded by Corporación CE-Marin through Convocatoria 14, 2018 supporting PhD candidates

Modelo procedimental para la caracterización y valoración de residuos de aparatos eléctricos y electrónicos, RAEE

The following work arises from the survey of information that allowed to evaluate the current situation of electrical and electronic waste (WEEE) in Chile. Identifying the characterization methods in each material to establish conditions, appraisals and procedures in the proper handling of these in post of the new Law of Extended Producer Responsibility (EPR). The result obtained establishes a procedural model applicable to the Teaching of Engineering and Design among other disciplines, which will systematize decision making and planning from an ecoefficient perspective, thus promoting projects of technological and economic interest for sustainable management of electrical and electronic waste.El siguiente trabajo surge a partir del relevamiento de información que permitió evaluar la situación actual de los residuos eléctricos y electrónicos (RAEE) en Chile. Identificando los métodos de caracterización en cada material para establecer condiciones, valorizaciones y procedimientos en el manejo adecuado de éstos en post de la nueva Ley de Responsabilidad extendida del Productor (REP). El resultado obtenido establece un modelo procedimental aplicable a la Enseñanza de la Ingeniería y el Diseño entre otras disciplinas, que permitirá sistematizar la toma de decisiones y la planeación desde una perspectiva Ecoeficiente, potenciando de esta forma proyectos de interés tecnológico y económico para el manejo sostenible de los residuos eléctricos y electrónicos.O trabalho surge a partir do relevamento de informação que permitiu avaliar a situação atual dos resíduos elétricos e eletrônicos (RAEE) em Chile. Identificando os métodos de caracterização em cada material para estabelecer condições, valorizações e procedimentos na gestão adequada de estes em favor da nova Lei de Responsabilidade estendidas do Produtor (REP). O resultado obtido estabelece um modelo procedimental aplicável à engenharia e o design entre outras disciplinas, que permitirá sistematizar a tomada de decisões e o planejamento desde uma perspectiva eco – eficiente, potenciando deste modo projetos de interesse tecnológico e econômico para o manejo sustentável dos resíduos elétricos e eletrônicos

Environmental assessment: Landform Classification for Land Use Planning in Developed Areas: An Example in Segovia Province (Central Spain)

Landform-based physiographic maps, also called land systems inventories, have been widely and successfully used in undeveloped/rural areas in several locations, such as Australia, the western United States, Canada, and the British ex-colonies. This paper presents a case study of their application in a developed semi-urban/suburban area (Segovia, Spain) for land use planning purposes. The paper focuses in the information transfer process, showing how land use decision-makers, such as governments, planners, town managers, etc., can use the information developed from these maps to assist them. The paper also addresses several issues important to the development and use of this information, such as the goals of modem physiography, the types of landform-based mapping products, the problem of data management in developed areas, and the distinctions among data, interpretations, and decisions.Depto. de Geodinámica, Estratigrafía y PaleontologíaFac. de Ciencias GeológicasTRUEpu

Ergotism in a patient with antiretroviral therapy with protease inhibitors (ritonavir)

Ergotismo es el término usado para definir el efecto adverso producido por la administración de medicamentos derivados del Ergot. En general, es resultado de sobredosis o interacciones medicamentosas en su metabolismo, el cual se lleva a cabo por isoenzimas hepáticas del grupo del citocromo P450 y CYPA4. Entre estos efectos, el principal es el α-adrenérgico, que se caracteriza por un grave vasoespasmo, generalizado, con predominio en las extremidades inferiores, que puede llevar incluso a la isquemia de la extremidad y obligar a su amputación. En este artículo se presenta un caso de ergotismo de un hombre de 33 años de edad con antecedente de VIH, en manejo con ritonavir, quien consultó a un centro hospitalario por cefalea y fue manejado con ergotamina. El caso fue confirmado por medio de un examen Doppler arterial de las extremidades inferiores y requirió manejo endovascular. Finalmente, se amputó parte del área afectada.Reporte de caso3549-3552Ergotism is the term which is used to define the adverse effect produced by the administration of drugs derived from Ergot. Generally speaking, this adverse effect occurs as a result of an overdose or drug interactions in the metabolism, which is carried out by the isoenzymes of the P450 and CYPA4 cytochrome group. Among these effects, the main one is the alpha adrenergic agonista effect which is characterized by severe generalized vasospasm, predominantly in the lower extremities. This can even lead to limb ischemia and amputation. This article presents a case of ergotism in a 33-year old patient with an HIV diagnosis who was being medicated with Ritonavir. The patient went to a hospital center complaining of headache and was medicated with Ergotamine. The case was confirmed by an arterial Doppler exam of the lower extremities and endovascular management was required. The patient finally required an amputation of the affected area

Frequency of breast cancer with hereditary risk features in Spain: Analysis from GEICAM “El Álamo III” retrospective study

Purpose: To determine the frequency of breast cancer (BC) patients with hereditary risk features in a wide retrospective cohort of patients in Spain. Methods: a retrospective analysis was conducted from 10, 638 BC patients diagnosed between 1998 and 2001 in the GEICAM registry “El Álamo III”, dividing them into four groups according to modified ESMO and SEOM hereditary cancer risk criteria: Sporadic breast cancer group (R0); Individual risk group (IR); Familial risk group (FR); Individual and familial risk group (IFR) with both individual and familial risk criteria. Results: 7, 641 patients were evaluable. Of them, 2, 252 patients (29.5%) had at least one hereditary risk criteria, being subclassified in: FR 1.105 (14.5%), IR 970 (12.7%), IFR 177 (2.3%). There was a higher frequency of newly diagnosed metastatic patients in the IR group (5.1% vs 3.2%, p = 0.02). In contrast, in RO were lower proportion of big tumors (> T2) (43.8% vs 47.4%, p = 0.023), nodal involvement (43.4% vs 48.1%, p = 0.004) and lower histological grades (20.9% G3 for the R0 vs 29.8%) when compared to patients with any risk criteria. Conclusions: Almost three out of ten BC patients have at least one hereditary risk cancer feature that would warrant further genetic counseling. Patients with hereditary cancer risk seems to be diagnosed with worse prognosis factors

Atlas y libro rojo de la flora vascular amenazada de España: adenda 2010

Endemismo del centro-oeste y noroeste ibérico conocido de bastantes localidades, pero con área muy disyunta y con una ocupación real pequeña, con poblaciones fragmentadas constituidas por muy pocos individuos

Phenotypic profile of expanded NK cells in chronic lymphoproliferative disorders: a surrogate marker for NK-cell clonality

[EN]Currently, the lack of a universal and specific marker of clonality hampers the diagnosis and classification of chronic expansions of natural killer (NK) cells. Here we investigated the utility of flow cytometric detection of aberrant/altered NK-cell phenotypes as a surrogate marker for clonality, in the diagnostic work-up of chronic lymphoproliferative disorders of NK cells (CLPD-NK). For this purpose, a large panel of markers was evaluated by multiparametric flow cytometry on peripheral blood (PB) CD56(low) NK cells from 60 patients, including 23 subjects with predefined clonal (n = 9) and polyclonal (n = 14) CD56(low) NK-cell expansions, and 37 with CLPD-NK of undetermined clonality; also, PB samples from 10 healthy adults were included. Clonality was established using the human androgen receptor (HUMARA) assay. Clonal NK cells were found to show decreased expression of CD7, CD11b and CD38, and higher CD2, CD94 and HLADR levels vs. normal NK cells, together with a restricted repertoire of expression of the CD158a, CD158b and CD161 killer-associated receptors. In turn, NK cells from both clonal and polyclonal CLPD-NK showed similar/overlapping phenotypic profiles, except for high and more homogeneous expression of CD94 and HLADR, which was restricted to clonal CLPD-NK. We conclude that the CD94(hi)/HLADR+ phenotypic profile proved to be a useful surrogate marker for NK-cell clonality.This work has been partially supported by the following grants: FIS 02/1244-FEDER, DTS 15/00119-FEDER, RTICC RD06/0020/0035-FEDER and RTICC RD12/0036/0048-FEDER from the Fondo de Investigación Sanitaria, Instituto de Salud Carlos III, Ministerio de Economía y Competitividad, Madrid, Spain; SA103/03 and SA079U14 from the Consejería de Educación, Junta de Castilla y León, Valladolid, Spain. The research activities of the EuroFlow Consortium were supported by the European Commission (grant STREP EU-FP6, LSHB-CT-2006–018708, entitled ‘Flow cytometry for fast and sensitive diagnosis and follow-up of hematological malignancies’)

Hospitalizations associated with rotavirus gastroenteritis in Spain, 2001–2005

<p>Abstract</p> <p>Background</p> <p>This study aims to describe and analyze hospital admissions in Spain due to rotavirus infections among children aged 5 years or under during the period 2001–2005, along with the associated health cost.</p> <p>Methods</p> <p>To update estimates of rotavirus hospitalizations rates in Spain, we conducted a retrospective study of 5 years of national hospitalization data associated with acute gastroenteritis using the Minimum Basic Data Set.</p> <p>Results</p> <p>During the study period, a total of 17.1% of all admissions due to acute gastroenteritis of any etiology in children aged ≤ 5 years were attributable to rotavirus infection as determined by the rotavirus-specific International Classification of Diseases, ninth revision, Clinical Modification code. A mean incidence of 135 hospital admissions attributable to rotavirus per 100,000 children aged ≤ 5 years was found. Hospitalizations associated with rotavirus had a marked winter-time seasonality. The estimated cost of hospital admission attributable to rotavirus has risen from 3 million euros estimated for 2001 to almost 7 million euros estimated in 2005.</p> <p>Conclusion</p> <p>Rotavirus gastroenteritis remains an important cause of hospitalizations in Spanish children, mostly during the winter season.</p