Estilos de pensamiento en universitarios y su relación con el Espacio Europeo de Educación Superior

Los estilos de pensamiento, tal como establece la Teoría del Autogobierno Mental de Sternberg (1999), representan la forma en que cada individuo prefiere procesar la información y tratar con las tareas, lo que relacionado con el ámbito académico y con las diferencias individuales entorno al rendimiento, puede suponer que los estudiantes obtengan mejores resultados ante determinados tipos de actividades y con unos sistemas de evaluación concretos. El presente trabajo se ha desarrollado con la intención de conocer, qué estilos de pensamiento son los más representativos en los estudiantes universitarios de primer curso, y además, reflexionar de manera teórica, acerca de aquellos que con el nuevo sistema de enseñanza-aprendizaje de la futura Educación Superior, se ajustarán más favorablemente a las exigencias del Espacio Europeo. Para ello se ha trabajado con una muestra de 559 alumnos/as de primer curso de la Universidad de Oviedo, con un total de 190 hombres (34 %) y 369 mujeres (66 %), que han respondido al Thinking Styles Questionnaire for Students (TSQS) de Sternberg y Wagner (1991).Thinking Styles, as Stenberg (1999) sets in his Mental Self-Government Theory, represent the way each individual prefers to process information and face the tasks. Referring to the academic area and individual differences in achievement it could mean that students reach a better performance on some specific tasks with a particular assessment method. This work has been developed to know what the most representative first-year students´ Thinking Styles are and which of them fits or fit better with the new teaching-learning process that the EHEA enacts. For this aim the present research works with a sample of 559 first-year students from the University of Oviedo, 190 men (34 %) and 369 women (66 %), who answered the Thinking Styles Questionnaire for Students (TSQS) (Sternberg & Wagner, 1991).peerReviewe

Metagenome sequencing of prokaryotic microbiota from two hypersaline ponds of a marine saltern in Santa Pola, Spain

Marine salterns are composed of several shallow ponds with a salinity gradient, from seawater to salt saturation, with gradually changing microbial populations. Here, we report the metagenome sequencing of the prokaryotic microbiota of two ponds with 13% and 33% salinity from a saltern in Santa Pola, Spain

Metagenomic sequence of prokaryotic microbiota from an intermediate-salinity pond of a saltern in Isla Cristina, Spain

Marine salterns are artificial multipond systems designed for the commercial production of salt by evaporation of seawater. We report here the metagenomic sequence of the prokaryotic microbiota of a pond with intermediate salinity (21% total salts) of a saltern located in Isla Cristina, Huelva, southwest Spain

Social sciences, art and physical activity in leisure environments. An inter-disciplinary project for teacher training

Factors such as social change and increasing urbanization processes in the early years of the 21st century have caused a reduction in the amount of time that children devote to leisure activities in the open-air, resulting in more sedentary lifestyles than children in previous decades. An education in healthy habits from early ages to increase children’s physical and mental well-being together with their level of cultural knowledge contributes to the acquisition of a Leisure Culture that allows children to perceive the close environment as a scene for learning and enjoyment. It is thus be necessary for schools to foster pedagogical experiences, taking the physical and cultural environment as teaching resources. An innovation project is proposed which will be implemented with 25 university students from the School of Teacher Training and Education at the University of Oviedo (Oviedo, Spain). The project will consist of the proposal of educational itineraries through the city of Oviedo and Mount Naranco. As teachers-to-be, students must combine knowledge of the related areas and generate inter-disciplinary activities throughout the routes that will foster respect for the environment and leisure based on culture and physical activity, attitudes that they will transmit to their own students in the future

Draft Genome of Spiribacter salinus M19-40, an Abundant Gammaproteobacterium in Aquatic Hypersaline Environments

We have previously used a de novo metagenomic assembly approach to describe the presence of an abundant gammaproteobacterium comprising nearly 15% of the microbial community in an intermediate salinity solar saltern pond. We have obtained this microbe in pure culture and describe the genome sequencing of the halophilic photoheterotrophic microbe, Spiribacter salinus M19-40

3D-printed PLA medical devices: physicochemical changes and biological response after sterilisation treatments

Financiado para publicación en acceso aberto: Universidade de Vigo/CISUGPolylactic acid (PLA) has become one of the most commonly used polymers in medical devices given its biocompatible, biodegradable and bioabsorbable properties. In addition, due to PLA’s thermoplastic behaviour, these medical devices are now obtained using 3D printing technologies. Once obtained, the 3D-printed PLA devices undergo different sterilisation procedures, which are essential to prevent infections. This work was an in-depth study of the physicochemical changes caused by novel and conventional sterilisation techniques on 3D-printed PLA and their impact on the biological response in terms of toxicity. The 3D-printed PLA physicochemical (XPS, FTIR, DSC, XRD) and mechanical properties as well as the hydrophilic degree were evaluated after sterilisation using saturated steam (SS), low temperature steam with formaldehyde (LTSF), gamma irradiation (GR), hydrogen peroxide gas plasma (HPGP) and CO2 under critical conditions (SCCO). The biological response was tested in vitro (fibroblasts NCTC-929) and in vivo (embryos and larvae wild-type zebrafish Danio rerio). The results indicated that after GR sterilisation, PLA preserved the O:C ratio and the semi-crystalline structure. Significant changes in the polymer surface were found after HPGP, LTSF and SS sterilisations, with a decrease in the O:C ratio. Moreover, the FTIR, DSC and XRD analysis revealed PLA crystallisation after SS sterilisation, with a 52.9% increase in the crystallinity index. This structural change was also reflected in the mechanical properties and wettability. An increase in crystallinity was also observed after SCCO and LTSF sterilisations, although to a lesser extent. Despite these changes, the biological evaluation revealed that none of the techniques were shown to promote the release of toxic compounds or PLA modifications with toxicity effects. GR sterilisation was concluded as the least reactive technique with good perspectives in the biological response, not only at the level of toxicity but at all levels, since the 3D-printed PLA remained almost unaltered.POCTEP INTERREG España- Portugal | Ref. BLUEBIOLABInterreg Atlantic Area | Ref. BLUEHUMAN EAPA_151/2016Ministerio de Ciencia e Innovación | Ref. PID 2020-115415RB-100Xunta de Galicia | Ref. ED431C 2021/49Xunta de Galicia | Ref. ED481A 2019/314Xunta de Galicia | Ref. IN606A-2017/011Fundação para a Ciência e a Tecnologia | Ref. UIDB/50016/202

Regulation of the transcriptional program by DNA methylation during human αβ T-cell development

© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. Thymocyte differentiation is a complex process involving well-defined sequential developmental stages that ultimately result in the generation of mature T-cells. In this study, we analyzed DNA methylation and gene expression profiles at successive human thymus developmental stages. Gain and loss of methylation occurred during thymocyte differentiation, but DNA demethylation was much more frequent than de novo methylation and more strongly correlated with gene expression. These changes took place in CpG-poor regions and were closely associated with T-cell differentiation and TCR function. Up to 88 genes that encode transcriptional regulators, some of whose functions in T-cell development are as yet unknown, were differentially methylated during differentiation. Interestingly, no reversion of accumulated DNA methylation changes was observed as differentiation progressed, except in a very small subset of key genes (RAG1, RAG2, CD8A, PTCRA, etc.), indicating that methylation changes are mostly unique and irreversible events. Our study explores the contribution of DNA methylation to T-cell lymphopoiesis and provides a fine-scale map of differentially methylated regions associated with gene expression changes. These can lay the molecular foundations for a better interpretation of the regulatory networks driving human thymopoiesis.Plan Nacional de [I+D+I 2008–2011]; Instituto de Salud Carlos III [grant number PI12/02587]; Red Española de Investigación Renal (REDinREN) [grant number RD12/0021/0018 and RD12/0021/0021]; Spanish Ministry of Science and Innovation [grant number SAF2010- 15106 and PLE2009-0110]; European Union [Fondos FEDER]Peer Reviewe

Autocuidado y su relación con factores sociolaborales en Psicólogos Clínicos: Un Estudio sobre Prácticas de Bienestar Profesional

The research analyzed the Self-care guidelines and their relationship with socio-labour factors in Clinical Psychologists within the line of research of Professional Well-being Practices. Variables related to self-care actions, self-care patterns according to marital status, seniority in the profession and frequency of self-care according to working hours were analyzed. The methodology used is descriptive-correlational with a quantitative approach and a prospective cross-sectional non-experimental design. A questionnaire was applied to a sample of clinical psychologists at the national level in Paraguay. The results allow us to conclude that most clinical psychologists recognize the importance of self-care and tend to practice it with some frequency. However, specific groups are identified, such as separated or divorced psychologists and those with more professional experience, who dedicate less dedication to maintaining regular self-care practices. In addition, the importance of providing resources and strategies to balance the workload with self-care in all clinical psychologists is highlighted, to improve their emotional well-being and quality of work life, which in turn can positively impact their ability to provide quality care to their patients.La investigación analizó las pautas de Autocuidado y su relación con factores sociolaborales en Psicólogos Clínicos dentro de la línea de investigación de Prácticas de Bienestar Profesional. Se analizaron variables relacionadas con acciones de autocuidado, patrones de autocuidado según su estado civil, según su antigüedad en la profesión y frecuencia de autocuidado según horas de trabajo. La metodología utilizada es de nivel descriptivo – correlacional con enfoque cuantitativo y de diseño no experimental trasversal prospectivo. Se empleó un cuestionario a una muestra de psicólogos clínicos de Asunción y del Departamento Central en Paraguay. Los resultados permiten concluir que la mayoría de los psicólogos clínicos reconocen la importancia del autocuidado y tienden a practicarlo con cierta frecuencia. Sin embargo, se identifican grupos específicos, como los psicólogos separados o divorciados y aquellos con mayor experiencia profesional, son los que dedican menor dedicación por mantener prácticas regulares de autocuidado. Además, se destaca la importancia de brindar recursos y estrategias para equilibrar la carga laboral con el autocuidado en todos los psicólogos clínicos, con el fin de mejorar su bienestar emocional y calidad de vida laboral, lo que a su vez puede impactar positivamente en su capacidad para brindar una atención de calidad a sus pacientes

Analysis of the impact of social determinants and primary care morbidity on population health outcomes by combining big data: A research protocol

In recent years, different tools have been developed to facilitate analysis of social determinants of health (SDH) and apply this to health policy. The possibility of generating predictive models of health outcomes which combine a wide range of socioeconomic indicators with health problems is an approach that is receiving increasing attention. Our objectives are twofold: (1) to predict population health outcomes measured as hospital morbidity, taking primary care (PC) morbidity adjusted for SDH as predictors; and (2) to analyze the geographic variability of the impact of SDH-adjusted PC morbidity on hospital morbidity, by combining data sourced from electronic health records and selected operations of the National Statistics Institute (Instituto Nacional de Estadística/INE).MethodsThe following will be conducted: a qualitative study to select socio-health indicators using RAND methodology in accordance with SDH frameworks, based on indicators published by the INE in selected operations; and a quantitative study combining two large databases drawn from different Spain’s Autonomous Regions (ARs) to enable hospital morbidity to be ascertained, i.e., PC electronic health records and the minimum basic data set (MBDS) for hospital discharges. These will be linked to socioeconomic indicators, previously selected by geographic unit. The outcome variable will be hospital morbidity, and the independent variables will be age, sex, PC morbidity, geographic unit, and socioeconomic indicators.AnalysisTo achieve the first objective, predictive models will be used, with a test-and-training technique, fitting multiple logistic regression models. In the analysis of geographic variability, penalized mixed models will be used, with geographic units considered as random effects and independent predictors as fixed effects.DiscussionThis study seeks to show the relationship between SDH and population health, and the geographic differences determined by such determinants. The main limitations are posed by the collection of data for healthcare as opposed to research purposes, and the time lag between collection and publication of data, sampling errors and missing data in registries and surveys. The main strength lies in the project’s multidisciplinary nature (family medicine, pediatrics, public health, nursing, psychology, engineering, geography)

Soluble co-signaling molecules predict long-term graft outcome in kidney-transplanted patients

Co-signaling molecules are responsible for full T-cell activation after solid organ transplantation. Their increased expression can lead to the release of a soluble form that can modulate the immune response post-transplantation. We analyzed the presence of co-signaling molecules (sCD30, sCD40, sCD137, sCTLA-4, sCD80, sCD28, sCD40L, sPD-1, and sPD-L1) in serum from kidney-transplanted patients (n = 59) obtained at different times (before transplantation, and 15 days, 3 months and 1 year post-transplantation) and their contribution to graft outcome was evaluated using principal component analysis. Before transplantation, high levels of soluble co-signaling molecules (mainly sCD30, sCD137 and sCD40) were detected in all patients. These molecules were modulated soon after receiving an allograft but never attained similar levels to those of healthy controls. A signature based on the determination of six soluble co-stimulatory (sCD30, sCD40, sCD137 and sCD40L) and co-inhibitory (sPD-1 and sPD-L1) molecules at 3 months post-transplantation allowed a group of patients to be identified (27.12%) with a worse long-term graft outcome. Patients with high levels of soluble molecules showed a progressive and gradual deterioration of kidney function (increased creatinine and proteinuria levels and decreased estimated glomerular filtration rate) over time and a higher risk of graft loss at 6 years post-transplantation than patients with low levels of these molecules (62.55% versus 5.14%, p<0.001). Thus, our data show an aberrant expression of soluble co-signaling molecules in kidney-transplanted patients whose quantification at 3 months post-transplantation might be a useful biomarker of immune status and help to predict long-term graft evolution