Dissolved Organic Matter in the Gulf of Cadiz: Distribution and Drivers of Chromophoric and Fluorescent Properties

The Gulf of Cadiz (GoC) connects the Mediterranean Sea with the Atlantic Ocean through the Strait of Gibraltar. Particular hydrographic processes take place in the GoC, such as riverine discharges and surface circulation marked by wind-induced seasonal upwelling. Although physical processes have been widely studied, little is known about the biogeochemical processes that occur in the basin, especially those involving organic matter. Therefore, vertical and seasonal dynamics of dissolved organic carbon (DOC) and optical properties of dissolved organic matter (DOM, absorbance and fluorescence) were measured in 766 samples collected between 5 and 800 m depth during four oceanographic cruises to obtain quantitative and qualitative information about DOM in the GoC. We performed parallel factor analysis (PARAFAC) to identify the main fluorophores present in the GoC, and an optimum multiparameter water mass analysis to differentiate the effect of water mass mixing from the biogeochemical processes in deep waters. PARAFAC analysis validated six fluorescent components; three humic-like, two protein-like, and a possible mixture of polycyclic aromatic hydrocarbon-like with protein-like material. DOC average concentration was 77.0 +/- 12.7 mu M, with higher values in surface and coastal waters during summer, mainly related to primary production. Linear relationships between DOC and apparent oxygen utilization indicate differences in oxygen consumption within the deep waters, which could be related to upwelling zones. Seasonal and spatial differences were also observed in the distribution of fluorescent DOM. Protein-like components were the most abundant fraction, with an average contribution of 64.75% +/- 7.85%, being higher in summer and surface waters, associated with an increase in biological activity. Our results indicate that water mass mixing is the main driver of the major humic-like components, while biogeochemical processes at a local scale explain DOC and protein-like components distribution. Our findings suggest that modeling DOM dynamics in the GoC is complicated due to its complex hydrography and the presence of multiple sources and sinks of DOM

AVALIAÇÃO DA IMPLEMENTAÇÃO DO PROGRAMA DE GESTÃO DE MATERIAIS E EQUIPAMENTOS ASSOCIADO AO PLANEJAMENTO ESTRATÉGICO DO HU/UFSC

Os hospitais de ensino vêm passando por profundas e aceleradas transformações, sobretudo decorrentes da implantação de novas políticas para a saúde. Para alcançarem suas metas esses hospitais, em especial, o Hospital Universitário Prof. Polydoro Ernani de São Thiago da Universidade Federal de Santa Catarina – HU/UFSC, foco desse estudo, tem sido forçado a adotar ferramentas mais eficazes de gestão, entre as quais está a elaboração de um planejamento estratégico. Foi a partir desse escopo, que surgiu o planejamento estratégico no HU/UFSC, intitulado de Plano 2012, que desde o inicio configurou-se como uma poderosa ferramenta capaz de auxiliar na tomada de decisão e apoiar ao necessário processo de mudança da organização. Considerando que o planejamento estratégico é um processo composto por ações inter-relacionadas e interdependentes, essa pesquisa se propôs avaliar a implementação das ações estratégicas formuladas no Programa de Gestão de Materiais e Equipamentos, associado ao Plano 2012. Como resultado da pesquisa concluiu-se que, a despeito de sua importância, nenhuma das ações estratégicas desse Programa foram efetivamente implementadas, o que caracterizou uma grande fragilidade dessa área, frente às novas demandas impostas ao HU/UFSC

Measuring adherence to inhaled control medication in patients with asthma: Comparison among an asthma app, patient self-report and physician assessment

Previous studies have demonstrated the feasibility of using an asthma app to support medication management and adherence but failed to compare with other measures currently used in clinical practice. However, in a clinical setting, any additional adherence measurement must be evaluated in the context of both the patient and physician perspectives so that it can also help improve the process of shared decision making. Thus, we aimed to compare different measures of adherence to asthma control inhalers in clinical practice, namely through an app, patient self-report and physician assessment. This study is a secondary analysis of three prospective multicentre observational studies with patients (≥13 years old) with persistent asthma recruited from 61 primary and secondary care centres in Portugal. Patients were invited to use the InspirerMundi app and register their inhaled medication. Adherence was measured by the app as the number of doses taken divided by the number of doses scheduled each day and two time points were considered for analysis: 1-week and 1-month. At baseline, patients and physicians independently assessed adherence to asthma control inhalers during the previous week using a Visual Analogue Scale (VAS 0-100). A total of 193 patients (72% female; median [P25-P75] age 28 [19-41] years old) were included in the analysis. Adherence measured by the app was lower (1 week: 31 [0-71]%; 1 month: 18 [0-48]%) than patient self-report (80 [60-95]) and physician assessment (82 [51-94]) (p 0.05). There was a moderate correlation between patient self-report and physician assessment (ρ = 0.596, p < 0.001). Adherence measured by the app was lower than that reported by the patient or the physician. This was expected as objective measurements are commonly lower than subjective evaluations, which tend to overestimate adherence. Nevertheless, the low adherence measured by the app may also be influenced by the use of the app itself and this needs to be considered in future studies.info:eu-repo/semantics/publishedVersio

ANICE : An Artificial Neuro-Linguistic Interactive Computer Entity

Mental health problems are hard to talk about, especially when the questions asked do not allow the individual to answer freely. That is the case for most inquiries, where questions usually request very restricted answers like yes or no. This thesis proposes a chatbot that tries to avoid the problem of restricting users to small answers. The chatbot will focus on people feeling burned out due to stress related to their studies. The chatbot tries to replicate two forms with questions about burnout that are used as guidelines. Both these forms are developed based on questions done by psychologists. Because rule-based chatbots have a limited vocabulary, natural language understand- ing and neural-based techniques are tested and validated to see if the chatbot performs well using these techniques. The techniques tested are word2vec and spacy components. The evaluation results show that it is feasible to implement a chatbot that uses rules and also techniques for natural language processing. Additionally, the tests did indicate that both spacy and word2vec are great resources for NLU. Word2vec proves to perform slightly better at specific times related to identifying intents that are domain-specific. Finally, the results from the users experience show that this is a promising work that could help students dealing with burnout.Problemas de saúde mental são um tema difícil de abordar, especialmente quando as perguntas feitas não permitem ao indivíduo responder livremente. Este é o caso da maio- ria dos inquéritos, onde as perguntas geralmente exigem respostas muito restritas, como sim ou não. Esta tese propõe um chatbot que tenta evitar o problema de restringir os utilizadores a pequenas respostas. O chatbot concentrar-se-á em utilizadores que se sen- tem esgotados devido ao stress relacionado com os estudos. O chatbot tenta replicar dois formulários com perguntas sobre burnout, isto é, estes formulários são utilizados como diretrizes. Ambos os formulários são desenvolvidos com base em perguntas feitas por psicólogos. Como os chatbots baseados em regras têm um vocabulário limitado, a compreensão da linguagem natural e as técnicas baseadas em redes neuronais são testadas e validadas para ver se o chatbot tem um bom funcionamento utilizando essas técnicas. As técnicas baseadas em redes neuronais que são testadas são o word2vec e componentes spacy. Os resultados da avaliação mostram que é viável implementar um chatbot que uti- lize regras e também técnicas de processamento de linguagem natural. Além disso, os testes indicam que tanto os componentes spacy quanto o word2vec são ótimos recursos para processamento de linguagem natural. O Word2vec tem um desempenho um pouco melhor em momentos específicos relacionados à identificação de intenções do domínio de estudo. Por fim, os resultados da experiência dos utilizadores mostram que este é um trabalho promissor que pode ajudar os utilizadores a lidar com o burnout

A INFLUÊNCIA DA LIDERANÇA NA CONDUÇÃO DO PROCESSO DE IMPLEMENTAÇÃO DO PLANEJAMENTO ESTRATÉGICO

Os hospitais de ensino vêm passando por profundas e aceleradas transformações, sobretudo decorrentes da implantação de novas políticas para a saúde. Para alcançarem suas metas e manter-se competitivas, essas instituições tem sido forçadas a adotar ferramentas mais eficazes de gestão, entre as quais está a elaboração de um planejamento estratégico. Este estudo tem como objetivo central, analisar qual a influência da liderança na condução do processo de implementação do planejamento estratégico em um hospital de ensino. O estudo foi realizado no Hospital Universitário Prof. Polydoro Ernani de São Thiago da Universidade Federal de Santa Catarina – HU/UFSC, onde foi realizada entrevista semi-estruturada com o coordenador da Equipe de Planejamento Estratégico do HU/UFSC. Autores como Bennis (1999), Drucker (2006), Senge (1990, 1999), entre outros, fundamentaram teoricamente o tema liderança. O tema planejamento estratégico foi fundamentado, principalmente pelos autores Ansoff (l987), Mintzberg (2004), Hrebiniak (2006) e Pereira (2010). Com os resultados da pesquisa, pode-se concluir a grande influência que a liderança exerce na condução do processo de implementação do planejamento estratégico

The effect of botulinum toxin type A injection in the viability of dorsal flap in rats

Purpose: Botulinum toxin A (BoNTA) increased the viability of skin flap in healthy rats. Most of the studies injected&nbsp;this substance some days (7-15) before the flap surgery. This treatment is used only for elective surgery, there was no data&nbsp;about the efficacy of BontA when injected in the surgical period. This study aimed to analyze the effect of BontA on the&nbsp;viability of Random flap in a intra surgical injection.&nbsp;Methods: Twenty male Wistar rats (250–300 g) were randomly divided into four groups: saline injection 15 days prior&nbsp;the surgery (G1), BoNTA injection 15 days prior the surgery (G2), saline injection intraoperative period (G3), BoNTA&nbsp;injection intraoperative (G4). A dorsal cutaneous flap (3×10cm) was performed. Survival area and total area of the flaps&nbsp;were measured. Lumen diameter, external arterial diameter and lumen/wall thickness ratio were recorded.&nbsp;Results: Viable area increased in Bonta 15days group when compared to saline-15days (1080.7 ± 307.5 mm2 vs. 1594.5&nbsp;± 419.7mm2, p= 0.01) and in the Bonta –intraoperative injection when compared to saline intraoperative injection (1133.3&nbsp;± 462.0 mm2 vs. 1389.9 ± 320.4 mm2, p=0.014). The ratio viable area/total area showed similar results (G1 versus G2,&nbsp;0.43 vs. 0.74; p&lt;0.001, respectively) and G3 versus G4 (0.44 vs. 0.61 p= 0,04). We did not find any difference in the&nbsp;microscopic analysis (lumen diameter, external arterial diameter and lumen/wall thickness ratio).&nbsp;Conclusion: BoNTA injected fifteen days before the surgery increased skin flap viability. However, BontA injected intraoperatory&nbsp;time did not increased the flap viability

Submarine mud volcanoes as a source of chromophoric dissolved organic matter to the deep waters of the Gulf of Cadiz

Seafloor structures related to the emission of different fluids, such as submarine mud volcanoes (MVs), have been recently reported to largely contribute with dissolved organic matter (DOM) into the oceans. Submarine MVs are common structures in the Gulf of Cadiz. However, little is known about the biogeochemical processes that occur in these peculiar environments, especially those involving DOM. Here, we report DOM characterization in the sediment pore water of three MVs of the Gulf of Cadiz. Estimated benthic fluxes of dissolved organic carbon (DOC) and chromophoric DOM (CDOM) were higher than in other marine sediments with an average of 0.11 +/- 0.04 mmol m(-2) d(-1) for DOC and ranging between 0.11 and 2.86 m(-1) L m(-2) d(-1), for CDOM. Protein-like components represented similar to 70% of the total fluorescent DOM (FDOM). We found that deep fluids migration from MVs (cold seeps) and anaerobic production via sulfate-reducing bacteria represent a source of DOC and FDOM to the overlying water column. Our results also indicate that fluorescent components can have many diverse sources not captured by common classifications. Overall, MVs act as a source of DOC, CDOM, and FDOM to the deep waters of the Gulf of Cadiz, providing energy to the microbial communities living there

Uso de ultrasonido para guiar la punción venosa periférica en niños: significado para la enfermera

OBJECTIVE: To understand the meaning of technological innovations applied in pediatric nurse, such as ultrasound to guide peripheral venipuncture in hospitalized children. METHODS: It is a descriptive and qualitative research conducted in a pediatric surgery unit of a teaching hospital, in the city of São Paulo. Semi-structured interviews were conducted with eight nurses. The qualitative content analysis was utilized to guide the collection and analysis of data. RESULTS: The analysis identified that the challenge weas the element that motivated the nurse to promote their adaptation to technological innovation in their practice. CONCLUSION: It is necessary to invest in studies to help broaden the understanding of this process to stimulate the development, implementation and use of changes in current professional practice.OBJETIVO: Comprender el significado de una aplicación de innovación tecnológica para la enfermera pediatra, como es el caso de ultrasonido utilizado guiar la punción venosa periférica en niños hospitalizados. MÉTODOS: Se trata de una investigación descriptiva de abordaje cualitativo, realizada en una unidad de cirugía pediátrica en un hospital vinculado a la enseñanza, en la ciudad de São Paulo. Fueron realizadas entrevistas semiestructuradas con ocho enfermeras. El análisis cualitativo de contenido fue aplicado para guiar la recolección y análisis de los datos. RESULTADOS: El análisis permitió identificar que el desafío es el elemento que motiva a la enfermera a promover la adaptación a la innovación tecnológica en su práctica. CONCLUSIÓN: Es necesario realizar inversiones en estudios que ayuden a ampliar la comprensión de ese proceso, a fin de estimular el desarrollo, la aplicación y la utilización de las innovaciones en lo cotidiano profesional.OBJETIVO: Compreender o significado da aplicação de inovação tecnológica para a enfermeira pediatra, como o ultra-som para guiar a punção venosa periférica em crianças hospitalizadas. MÉTODOS: Pesquisa descritiva de abordagem qualitativa realizada em uma unidade de cirurgia pediátrica de um hospital vinculado ao ensino, na cidade de São Paulo. Foram realizadas entrevistas semi-estruturadas com oito enfermeiras. A análise qualitativa de conteúdo foi aplicada para guiar a coleta e análise dos dados. RESULTADOS: A análise permitiu identificar que o desafio é o elemento motivador da enfermeira para promover sua adaptação à inovação tecnológica em sua prática. CONCLUSÃO: É necessário investir em estudos que ajudem a ampliar a compreensão desse processo, de maneira a estimular o desenvolvimento, a aplicação e a utilização das mudanças no cotidiano profissional.Universidade Federal de São Paulo (UNIFESP) Departamento de EnfermagemUNIFESP, Depto. de EnfermagemSciEL