The computer as a tool for the writer: the quest for the "right" word

This symposium paper discusses the role of dictionaries in the process of writing and the effects of computerization. The authors include examples of several different hypothetical lexical searches and their outcomes, based on a writer's needs, and argue that these relationships differ from what is to be found in lexicons. A key point is that writers often want to break habits of thought, predigested thinking and prejudice, in which case dictionaries will not directly serve their writing requirements. The dictionary could be seen as a decision support system for writing, with a computerized system that tracks what has been written and suggests ideas based on the evolving text or on dictionary searches carried out or attempted by the writer

Single-molecule transport of fullerene-based curcuminoids

We present experimental and theoretical studies of single-molecule conductance through nonplanar fullerocurcuminoid molecular dyads in ambient conditions using the mechanically controllable break junction technique. We show that molecular dyads with bare fullerenes form configurations with conductance features related to different transport channels within the molecules, as identified with filtering and clustering methods. The primary channel corresponds to charge transport through the methylthio-terminated backbone. Additional low-conductance channels involve one backbone side and the fullerene. In fullerenes with four additional equatorial diethyl malonate groups attached to them, the latter transport pathway is blocked. Density functional theory calculations corroborate the experimental observations. In combination with nonequilibrium green functions, the conductance values of the fullerocurcuminoid backbones are found to be similar to those of a planar curcuminoid molecule without a fullerene attached. In the nonplanar fullerocurcuminoid systems, the highest-conductance peak occurs partly through space, compensating for the charge delocalization loss present in the curcuminoid system

Grado de satisfaccion de egresados y graduados con la formacion recibida en el Programa de Magister en Politica y Gestion Educacional de la Universidad de Talca

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Target for PCR amplification on segment 5 as template.

<p>Insert 4 and amino acid in position 266 are indicated. Arrows indicate primer locations.</p

Phylogenetic tree of the <i>orthomyxoviridae</i> family (PB2 gene).

<p>A sub-tree for the <i>Isavirus</i> genus is observed in the lower right corner. The tree was constructed with reference sequences from GenBank database (Accession numbers; Influenza A: NC_004910, HQ117883, AJ40430; Influenza B: NC_002204, AF101982, EF626642; Influenza C: NC_006307, M28061, AF170576; ISAV: NC_006505, AY373381, DQ785183, EU118815, GU830895; Quaranjavirus: GQ499302; Thogotovirus: Y17783). The tree was inferred by using the Maximum Likelihood method based on the Tamura-Nei model with a bootstrap test (1000 replicates) using MEGA 5 software <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0087832#pone.0087832-Tamura1" target="_blank">[33]</a>.</p

Target for PCR amplification on segment 6 as template.

<p>HPR region is indicated. Arrows indicate primer locations.</p

High Resolution Melting Profiles for segment 5.

<p>The lower right corner shows the standard reference variants, with No Insert: red line, and with Insert 4: blue line. The analyzed samples all matched with the No Insert variant.</p

Summary of sequencing results for genomic segments 6 and 5.

<p>As reference sequences we used EU118820 for HPR0 variant and GU830900 for HPR7b variant from the GenBank database.</p>‡<p>Referred to the presence of insert-4 (IN4) and the specific amino acid (AA) in position 266.</p><p>ND: not determined.</p