310 research outputs found

    Anaphylaxis to clavulanic acid: seven-year survey

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    info:eu-repo/semantics/publishedVersio

    Development of weCope, a mobile app for illness self-management in schizophrenia

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    Objective: To describe the development of weCope, a Portuguese mobile app for people with schizophrenia. Methods: The development of weCope followed 4 stages: I-102 people with psychotic disorders completed an online questionnaire; II-a multidisciplinary focus group was conducted among five mental health professionals; III-we developed the app; IV-9 participants used weCope during 8 weeks to assess its efficiency. Results: weCope targets coping with voices, problem solving, goals setting and stress management, and results indicated that: weCope improved symptoms, sense of recovery and personal and social functioning; 59% of the participants were willing to download an application for illness self-management; professionals revealed some concerns about mHealth but enhanced the high importance to develop these apps; usability testing revealed that 89% considered weCope useful for illness self-management. However, the more years with mental illness, the less importance is given to a mobile application for this purpose. Discussion: weCope was developed through a comprehensive development process and may contribute to a subjective perception of the patient’s better well-being and health condition

    Internet of Things-Aided Smart Home Off-Grid Photovoltaic-Powered

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    Nowadays, smart devices which can be controlled remotely by the Internet appear in the preference setting rather than the manual control to improve the standard of living. In this paper, a domotic system integrated into PV power generation has been developed on the Internet of Things (IoT). The system uses sensors for fire detection and monitoring of the temperature and relative air humidity. Based on real-time, the home automation off-grid system is developed so that makes the system cost-effective and portable

    Quantitative and Qualitative Approach of Scientific Paper Popularity By Naïve Bayes Classifier

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    Usually, scientific research begins with the collection of data in which online social media tools can be some of the most rewarding and informative resources. The extensive measure of accessible information pulls in users from undergraduate students to postdoc. The search for scientific themes has popularized due to the availability of abundant publications that resides in scientific social networks such as Mendeley, ResearchGate etc. Articles are published on these media inform of text for knowledge dissemination, scientific support, research, updates etc, and are frequently uploaded after its publication in a proceedings or journal. In this sense, data collected from database often contains high noise and its analysis can be treated as a characterization undertaking as it groups the introduction of a content into either good or bad. In this text, we present quantitative and qualitative analysis of papers popularity in Mendeley repository by using naive Bayes Classifier

    Quantitative Analysis Powered by Naïve Bayes Classifier Algorithm to Data-Related Publications Social-Scientific Network

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    Quantitative evaluation of a dataset can play an important role in pattern recognition of technical-scientific research involving behavior and dynamics in social networks. As an example, are the adaptive feature weighting approaches by naive Bayes text algorithm. This work aims to present an exploratory data analysis with a quantitative approach that involves pattern recognition using the Mendeley research network; to identify logics given the popularity of document access. To better analyze the results, the work was divided into four categories, each with three subcategories, that is, five, three, and two output classes. The name for these categories came up due to data collection, which also presented documents with open access, dismembering proceedings, and journals for two more categories. As a result, the performance for the test examples showed a lower error rate related to the subcategory two output classes in the criterion of popularity by using the naive Bayes algorithm in Mendeley

    Enhancement of carrier lifetimes in type-II quantum dot/quantum well hybrid structures

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    FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORWe investigate optical transitions and carrier dynamics in hybrid structures containing type-I GaAs/AlGaAs quantum wells (QWs) and type-II GaSb/AlGaAs quantum dots (QDs). We show that the optical recombination of photocreated electrons confined in the QWs with holes in the QDs and wetting layer can be modified according to the QW/QD spatial separation. In particular, for low spacer thicknesses, the QW optical emission can be suppressed due to the transference of holes from the QW to the GaSb layer, favoring the optical recombination of spatially separated carriers, which can be useful for optical memory and solar cell applications. Time-resolved photoluminescence (PL) measurements reveal non-exponential recombination dynamics. We demonstrate that the PL transients can only be quantitatively described by considering both linear and quadratic terms of the carrier density in the bimolecular recombination approximation for type-II semiconductor nanostructures. We extract long exciton lifetimes from 700 ns to 5 mu s for QDs depending on the spacer layer thickness. Published by AIP Publishing.We investigate optical transitions and carrier dynamics in hybrid structures containing type-I GaAs/AlGaAs quantum wells (QWs) and type-II GaSb/AlGaAs quantum dots (QDs). We show that the optical recombination of photocreated electrons confined in the QWs with holes in the QDs and wetting layer can be modified according to the QW/QD spatial separation. In particular, for low spacer thicknesses, the QW optical emission can be suppressed due to the transference of holes from the QW to the GaSb layer, favoring the optical recombination of spatially separated carriers, which can be useful for optical memory and solar cell applications. Time-resolved photoluminescence (PL) measurements reveal non-exponential recombination dynamics. We demonstrate that the PL transients can only be quantitatively described by considering both linear and quadratic terms of the carrier density in the bimolecular recombination approximation for type-II semiconductor nanostructures. We extract long exciton lifetimes from 700 ns to 5 mu s for QDs depending on the spacer layer thickness.120817FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIORFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOCNPQ - CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOCAPES - COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR2012/11382-9 , 2014/17141-9Sem informaçãoSem informaçã

    Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology.

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    Trypanosoma cruzi, the flagellate protozoan agent of Chagas disease or American trypanosomiasis, is unable to synthesize sialic acids de novo. Mucins and trans-sialidase (TS) are substrate and enzyme, respectively, of the glycobiological system that scavenges sialic acid from the host in a crucial interplay for T. cruzi life cycle. The acquisition of the sialyl residue allows the parasite to avoid lysis by serum factors and to interact with the host cell. A major drawback to studying the sialylation kinetics and turnover of the trypomastigote glycoconjugates is the difficulty to identify and follow the recently acquired sialyl residues. To tackle this issue, we followed an unnatural sugar approach as bioorthogonal chemical reporters, where the use of azidosialyl residues allowed identifying the acquired sugar. Advanced microscopy techniques, together with biochemical methods, were used to study the trypomastigote membrane from its glycobiological perspective. Main sialyl acceptors were identified as mucins by biochemical procedures and protein markers. Together with determining their shedding and turnover rates, we also report that several membrane proteins, including TS and its substrates, both glycosylphosphatidylinositol-anchored proteins, are separately distributed on parasite surface and contained in different and highly stable membrane microdomains. Notably, labeling for α(1,3)Galactosyl residues only partially colocalize with sialylated mucins, indicating that two species of glycosylated mucins do exist, which are segregated at the parasite surface. Moreover, sialylated mucins were included in lipid-raft-domains, whereas TS molecules are not. The location of the surface-anchored TS resulted too far off as to be capable to sialylate mucins, a role played by the shed TS instead. Phosphatidylinositol-phospholipase-C activity is actually not present in trypomastigotes. Therefore, shedding of TS occurs via microvesicles instead of as a fully soluble form
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