You are What you Eat (and Drink): Identifying Cultural Boundaries by Analyzing Food & Drink Habits in Foursquare

Food and drink are two of the most basic needs of human beings. However, as society evolved, food and drink became also a strong cultural aspect, being able to describe strong differences among people. Traditional methods used to analyze cross-cultural differences are mainly based on surveys and, for this reason, they are very difficult to represent a significant statistical sample at a global scale. In this paper, we propose a new methodology to identify cultural boundaries and similarities across populations at different scales based on the analysis of Foursquare check-ins. This approach might be useful not only for economic purposes, but also to support existing and novel marketing and social applications. Our methodology consists of the following steps. First, we map food and drink related check-ins extracted from Foursquare into users' cultural preferences. Second, we identify particular individual preferences, such as the taste for a certain type of food or drink, e.g., pizza or sake, as well as temporal habits, such as the time and day of the week when an individual goes to a restaurant or a bar. Third, we show how to analyze this information to assess the cultural distance between two countries, cities or even areas of a city. Fourth, we apply a simple clustering technique, using this cultural distance measure, to draw cultural boundaries across countries, cities and regions.Comment: 10 pages, 10 figures, 1 table. Proceedings of 8th AAAI Intl. Conf. on Weblogs and Social Media (ICWSM 2014

A Human-machine Cooperation Protocol for Machine Translation Output Edit Annotation

We report on a study exploring automatic edit annotation in a post-editing corpus with a new method for computing edit types. We examine edit type association with quality scores assigned to the machine translation output and the post-edited texts. Finally, we account for shortcomings in our method and point out edit types worth leveraging.Presentem un estudi que explora la detecció automàtica d'errors en un corpus de postedició amb un mètode inèdit per calcular tipus d'edició. Examinem la seva associació amb les puntuacions de qualitat assignades a la producció de traducció automàtica i als textos posteditats. Finalment, expliquem les deficiències del nostre mètode i assenyalem els tipus d'edició que val la pena aprofitar.Presentamos un estudio que explora la detección automática de errores en un corpus de posedición con un método novedoso para computar los diferentes tipos de corrección. Examinamos su asociación con la puntuación asignada a la calidad de los resultados de la traducción automática y de los textos poseditados. Por último, analizamos algunos defectos de nuestro método y destacamos los tipos de correcciones que conviene aprovechar

Enhancement of antibiotic activity by Cordia verbenacea DC

Escherichia coli is known to produce enterotoxins whose properties and its role in diarrheal disease has been extensively investigated. Some species of Staphylococcus are often recognized as etiological agents of many animal and human opportunistic infections. This study is the first test of change in resistance of antibiotic activity by Cordia verbenacea DC. against multiresistant strains of Escherichia coli and Staphylococcus aureus. In this study, the hexane and methanol extract of Cordia verbenacea DC. were tested for antibacterial activity alone and in combination with aminoglycosides against bacterial strains. The synergy of the methanolic and hexane were verified by microdilution method. A synergistic effect of both extracts combined with the aminoglycosides was demonstrated. It is therefore suggested that the extracts from Cordia verbenacea DC. could be used as a source of natural products derived from this plant with resistance-modifying antibacterial activity, providing a new weapon against the problem of bacterial resistance to antibiotics.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Enhancement of antibiotic activity by Cordia verbenacea DC

Escherichia coli is known to produce enterotoxins whose properties and its role in diarrheal disease has been extensively investigated. Some species of Staphylococcus are often recognized as etiological agents of many animal and human opportunistic infections. This study is the first test of change in resistance of antibiotic activity by Cordia verbenacea DC. against multiresistant strains of Escherichia coli and Staphylococcus aureus. In this study, the hexane and methanol extract of Cordia verbenacea DC. were tested for antibacterial activity alone and in combination with aminoglycosides against bacterial strains. The synergy of the methanolic and hexane were verified by microdilution method. A synergistic effect of both extracts combined with the aminoglycosides was demonstrated. It is therefore suggested that the extracts from Cordia verbenacea DC. could be used as a source of natural products derived from this plant with resistance-modifying antibacterial activity, providing a new weapon against the problem of bacterial resistance to antibiotics.Colegio de Farmacéuticos de la Provincia de Buenos Aire

Evolving Convolutional Neural Networks for Glaucoma Diagnosis / Redes neurais convolucionais em evolução para diagnóstico de glaucoma

O glaucoma é uma doença ocular que causa danos ao nervo óptico do olho e sucessivo estreitamento do campo visual nos pacientes afetados, o que pode levar o paciente, em estágio avançado, à cegueira. Este trabalho apresenta um estudo sobre o uso de Redes Neurais Convolucionais (CNNs) para o diagnóstico automático através de imagens de fundo de olho. No entanto, a construção de uma CNN capaz de alcançar resultados satisfatórios para o diagnóstico do glaucoma, envolve muito esforço que, em muitas situações, nem sempre é capaz de tais resultados. O objetivo deste trabalho é utilizar um algoritmo genético (AG) para otimizar arquiteturas de CNNs através da técnica de evolução de algoritmos que possa aprimorar o diagnóstico do glaucoma em imagens de fundo do olho do conjunto de dados RIM-ONE-r2. Nosso artigo demonstra resultados satisfatórios após o treinamento do melhor indivíduo escolhido pelo AG, com a obtenção de uma acurácia de 91%

The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases

<p>Abstract</p> <p>Background</p> <p>Pathogens depend on peptidase activities to accomplish many physiological processes, including interaction with their hosts, highlighting parasitic peptidases as potential drug targets. In this study, a major leucyl aminopeptidolytic activity was identified in <it>Trypanosoma cruzi</it>, the aetiological agent of Chagas disease.</p> <p>Results</p> <p>The enzyme was isolated from epimastigote forms of the parasite by a two-step chromatographic procedure and associated with a single 330-kDa homohexameric protein as determined by sedimentation velocity and light scattering experiments. Peptide mass fingerprinting identified the enzyme as the predicted <it>T. cruzi </it>aminopeptidase EAN97960. Molecular and enzymatic analysis indicated that this leucyl aminopeptidase of <it>T. cruzi </it>(LAPTc) belongs to the peptidase family M17 or leucyl aminopeptidase family. LAPTc has a strong dependence on neutral pH, is mesophilic and retains its oligomeric form up to 80°C. Conversely, its recombinant form is thermophilic and requires alkaline pH.</p> <p>Conclusions</p> <p>LAPTc is a 330-kDa homohexameric metalloaminopeptidase expressed by all <it>T. cruzi </it>forms and mediates the major parasite leucyl aminopeptidolytic activity. Since biosynthetic pathways for essential amino acids, including leucine, are lacking in <it>T. cruzi</it>, LAPTc could have a function in nutritional supply.</p

Enhancement of antibiotic activity by Cordia verbenacea DC

Escherichia coli is known to produce enterotoxins whose properties and its role in diarrheal disease has been extensively investigated. Some species of Staphylococcus are often recognized as etiological agents of many animal and human opportunistic infections. This study is the first test of change in resistance of antibiotic activity by Cordia verbenacea DC. against multiresistant strains of Escherichia coli and Staphylococcus aureus. In this study, the hexane and methanol extract of Cordia verbenacea DC. were tested for antibacterial activity alone and in combination with aminoglycosides against bacterial strains. The synergy of the methanolic and hexane were verified by microdilution method. A synergistic effect of both extracts combined with the aminoglycosides was demonstrated. It is therefore suggested that the extracts from Cordia verbenacea DC. could be used as a source of natural products derived from this plant with resistance-modifying antibacterial activity, providing a new weapon against the problem of bacterial resistance to antibiotics.Colegio de Farmacéuticos de la Provincia de Buenos Aire