137 research outputs found

    THE APPLICATION OF SPEED READING AT INTERMEDIATE LEVEL (A Case Study of Qualitative Research in One of Senior High School at Majalengka)

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    Muhammad Salim Pajri. 14111330143. THE APPLICATION OF SPEED READING AT INTERMEDIATE LEVEL (A Case Study of Qualitative Research in One of Senior High School at Majalengka) Reading is the important things in education, because people can get knowledge and information from reading. Without reading people cannot absorb many sciences. Here, the researcher use speed reading technique as the tool of analyzing to know the learning and teaching process at intermediate level. Moreover, the aims of this research are (1). To know the teaching and learning process of speed reading. (2). To know students’ attitude towards teaching and learning speed reading. (3). To know overcome of the difficulties of speed reading. Theoretically, is regarding to the reading area, especially in the reading comprehension by using speed reading technique. Practically, the researcher will analyze of speed reading in one of Senior High School at Majalengka which has benefit for teacher to know students’ ability in school. The research finding and discussion told about the teaching and learning process of speed reading at intermediate level. There are three activities of speed reading techniques. (1) Preparation Activity: teacher begins with greetings, deliver material and prepare students by warming up to focuss in learning process. (2) Core Activity: teacher teaches all the materials of speed reading. (3) Follow-up Activity: teacher gives exercise as the activity to know students score of speed reading test. The result of the analysis shows there are 5 students’ attitude towards teaching and learning speed reading. then, the finding shows that (1). Students’ feeling towards teaching and learning using speed reading in general: students like speed reading then also comfortable. (2). Students’ feeling towards the process of teaching and learning speed reading: they get comprehension of this technique. (3). Students’ difficulties in learning using speed reading: there are unfamiliar word on athe text. (4). Students’ feeling towards their comprehension in learning using speed reading: they get purpose in speed reading learning. (5). Students’ motivation in learning using speed reading: they can read books in fast time. It was found the overcome of difficulties of speed reading technique they are the process of the teaching speed reading and response the students’ response towards it, difficulties, disadvantages and teaching using speed reading technique and the result, usefulness, critics, and suggestions of teaching using speed reading technique. From the research that has been done, it can be concluded that there is way to apply speed reading by using steps of speed reading. From this technique will increase students’ ability in reading process. It can help students to read fast and efficient time. Keywords: Reading Comprehension, Speed Reading, Intermediate Leve

    Charged-particle multiplicity distributions over a wide pseudorapidity range in proton-proton collisions at √s = 0.9, 7, and 8 TeV

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    We present the charged-particle multiplicity distributions over a wide pseudorapidity range (−3.4<η<5.0 ) for pp collisions at √s=0.9,7 , and 8 TeV at the LHC. Results are based on information from the Silicon Pixel Detector and the Forward Multiplicity Detector of ALICE, extending the pseudorapidity coverage of the earlier publications and the high-multiplicity reach. The measurements are compared to results from the CMS experiment and to PYTHIA, PHOJET and EPOS LHC event generators, as well as IP-Glasma calculations.publishedVersio

    Dehydroepiandrosterone sulfate mediates activation of transcription factors CREB and ATF-1 via a Gα11-coupled receptor in the spermatogenic cell line GC-2

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    AbstractDehydroepiandrosterone sulfate (DHEAS) is a circulating steroid produced in the adrenal cortex, brain, and gonads. Whereas a series of investigations attest to neuroprotective effects of the steroid in the brain, surprisingly little is known about the physiological effects of DHEAS on cells of the reproductive system. Here we demonstrate that DHEAS acting on the spermatogenic cell line GC-2 induces a time- and concentration-dependent phosphorylation of c-Src and Erk1/2 and activates the transcription factors activating transforming factor-1 (ATF-1) and cyclic AMP-responsive element binding protein (CREB). These actions are consistent with the non-classical signaling pathway of testosterone and suggest that DHEAS is a pro-androgen that is converted into testosterone in order to exert its biological activity. The fact, however, that steroid sulfatase mRNA was not detected in the GC-2 cells and the clear demonstration of DHEAS-induced activation of Erk1/2, ATF-1 and CREB after silencing the androgen receptor by small interfering RNA (siRNA) clearly contradict this assumption and make it appear unlikely that DHEAS has to be converted in the cytosol into a different steroid in order to activate the kinases and transcription factors mentioned. Instead, it is likely that the DHEAS-induced signaling is mediated through the interaction of the steroid with a membrane-bound G-protein-coupled receptor, since silencing of Guanine nucleotide-binding protein subunit alpha-11 (Gnα11) leads to the abolition of the DHEAS-induced stimulation of Erk1/2, ATF-1, and CREB. The investigation presented here shows a hormone-like activity of DHEAS on a spermatogenic cell line. Since DHEAS is produced in male and female reproductive organs, these findings could help to define new roles for DHEAS in the physiology of reproduction

    Jet shapes in pp and Pb–Pb collisions at ALICE

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    The aim of this work is to explore possible medium modifications to the substructure of inclusive charged jets in Pb-Pb relative to proton-proton collisions by measuring a set of jet shapes. The set of shapes includes the radial moment, g, and the momentum dispersion pTD. They provide complementary information on the fragmentation and can help to discriminate between two different scenarios: intra-jet broadening or collimation as a result of jet quenching. The shapes are measured in Pb–Pb collisions at √sNN = 2.76 TeV with a constituent cutoff of 0.15 GeV/c and jet resolution R = 0.2. New techniques for background subtraction are applied and a two-dimensional unfolding is performed to correct the shapes to particle level. The corrected jet shapes for jet pT 40 ≤ pT,jet ≤ 60 GeV/c are presented and discussed. The observed jet shape modifications suggest that the in-medium fragmentation is harder and more collimated than vacuum fragmentation as obtained by a PYTHIA calculation. The PYTHIA calculation is validated with proton-proton data at 7 TeV.publishedVersio

    Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

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    The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

    Hepatectomía parcial masiva como tratamiento de quistes hepáticos hemorrágicos en un gato Savannah

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    The transverse momentum distributions of the strange and double-strange hyperon resonances Σ(1385)±\Sigma(1385)^{\pm}. Ξ(1530)0\Xi(1530)^{0} produced in p-Pb collisions at sNN=5.02\sqrt{s_{\rm NN}} = 5.02 TeV were measured in the rapidity range 0.5<yCMS<0-0.5< y_{\rm{CMS}}<0 for event classes corresponding to different charged-particle multiplicity densities, dNch/dηlab\langle{\rm d}N_{\rm{ch}}/{\rm d}\eta_{\rm{lab}}\rangle. The mean transverse momentum values are presented as a function of dNch/dηlab\langle{\rm d}N_{\rm{ch}}/{\rm d}\eta_{\rm{lab}}\rangle. as well as a function of the particle masses and compared with previous results on hyperon production. The integrated yield ratios of excited to ground-state hyperons are constant as a function of dNch/dηlab\langle{\rm d}N_{\rm{ch}}/{\rm d}\eta_{\rm{lab}}\rangle. The equivalent ratios to pions exhibit an increase with dNch/dηlab\langle{\rm d}N_{\rm{ch}}/{\rm d}\eta_{\rm{lab}}\rangle. depending on their strangeness content

    Visiones

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    El trabajo obtuvo un Premio Tomás García Verdejo a las buenas prácticas educativas en la Comunidad Autónoma de Extremadura para el curso 2017/2018. Modalidad BSe presenta un proyecto llevado a cabo en la Escuela Oficial de Idiomas de Plasencia (Cáceres) que tenía como objetivo principal el uso de la lengua a través de actividades eminentemente comunicativas que fomenten las relaciones y la convivencia. Se desarrollaron 4 actividades: 'Visiones de Plasencia, El mercado' que pretendía mostrar la visión que los turistas y vecinos extranjeros tienen de Plasencia; 'Visiones de Europa', que consistió en contactar con un ilustrador gráfico y se le encargaron ilustraciones de 5 ciudades europeas, en torno a las cuales se realizaron distintas tareas; 'Visiones culturales' en la que teniendo como base siete ilustraciones de personajes famosos que destacaban por su labor profesional y contribución cultural se investigó sobre su vida y 'Visiones personales' que se construyó con retratos de la ciudad de Plasencia elaborados por los propios alumnos del centro (selfies)ExtremaduraES

    ALICE measurement of the J/ψJ/\psi nuclear modification factor at mid-rapidity in Pb–Pb collisions at sNN=\sqrt{{s}_{NN}}= 5.02 TeV

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    ALICE at the LHC provides unique capabilities to study charmonium production at low transverse momenta ( p T ). At central rapidity, ( |y|<0.8 ), ALICE can reconstruct J/ ψ via their decay into two electrons down to zero p T . Results at mid-rapidity on the inclusive J/ ψ nuclear modification factor RAA as a function of centrality in Pb-Pb collisions at sNN=5.02 TeV and comparisons to lower energies and models are shown. In addition, the yield of the J/ ψ produced with very low p T in the most peripheral collisions and the J/ ψ elliptic flow ( v2 ) are also presented
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