Monthly 43 GHz VLBA Polarimetric Monitoring of 3C120 over 16 Epochs: Evidence for Trailing Shocks in a Relativistic Jet

We present a 16-month sequence of monthly polarimetric 43 GHz VLBA images of the radio galaxy 3C 120. The images probe the inner regions of the radio jet of this relatively nearby superluminal radio galaxy at a linear resolution of 0.07 $h_{65}^{-1}$ pc ($H_o= 65 h_{65}$ km s$^{-1}$ Mpc$^{-1}$). We follow the motion of a number of features with apparent velocities between 4.01$\pm$0.08 and $5.82\pm 0.13 h_{65}^{-1} c$. A new superluminal knot, moving at $4.29\pm 0.16 h_{65}^{-1} c$, is observed to be ejected from the core at a time coincident with the largest flare ever observed for this source at millimeter wavelengths. Changes in the position angle of this component, as well as a progressive rotation of its magnetic polarization vector, suggest the presence of a twisted (resembling a helix in projection) configuration of the underlying jet magnetic field and jet geometry. We identify several knots that appear in the wake of the new superluminal component, moving at proper motions $\sim 4$ times slower than any of the other moving knots observed in 3C 120. These features have properties similar to those of the ``trailing'' shocks seen in relativistic, time-dependent, hydrodynamical and emission simulations of compact jets. Such trailing compressions are triggered by pinch-mode jet-body instabilities caused by the propagation of a strong perturbation, which we associate with the new strong superluminal component.Comment: 4 pages, 5 figures, accepted for publication in Astrophysical Journal Letter

MUC1 positive cutaneous metastasis with transepidermal elimination from a breast carcinoma

Breast cancer is the most common cause of cutaneous metastases from internal malignancies. Generally, the neoplastic cells are located in the dermis or hypodermis, while a finding of transepidermal elimination on cutaneous metastases is exceptional. In this report we present a patient with perforating cutaneous metastases from breast cancer with mucin 1 expression. Cutaneous, bone, lung, and hepatic lesions were detected two years after the diagnosis of the primary tumor.Fil: Luna, Amalia. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; ArgentinaFil: Merino, María Emilia. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; ArgentinaFil: Alberdi, Cecilio G.. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; ArgentinaFil: Abba, Martín Carlos. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Segal Eiras, Amada. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; ArgentinaFil: Croce, María Virginia. Universidad Nacional de La Plata. Facultad de Ciencias Médicas. Centro de Investigaciones Inmunológicas Básicas y Aplicadas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

The connection between radio and high energy emission in black hole powered systems in the SKA era

Strong evidence exists for a highly significant correlation between the radio flux density and gamma-ray energy flux in blazars revealed by Fermi. However, there are central issues that need to be clarified in this field: what are the counterparts of the about 30% of gamma-ray sources that are as yet unidentified? Are they just blazars in disguise or they are something more exotic, possibly associated with dark matter? How would they fit in the radio-gamma ray connection studied so far? With their superb sensitivity, SKA1-MID and SKA1-SUR will help to resolve all of these questions. Even more, while the radio-MeV/GeV connection has been firmly established, a radio-VHE connection has been entirely elusive so far. The advent of CTA in the next few years and the expected CTA-SKA1 synergy will offer the chance to explore this connection, even more intriguing as it involves the opposite ends of the electromagnetic spectrum and the acceleration of particles up to the highest energies. We are already preparing to address these questions by exploiting data from the various SKA pathfinders and precursors. We have obtained 18 cm European VLBI Network observations of E>10 GeV sources, with a detection rate of 83%. Moreover, we are cross correlating the Fermi catalogs with the MWA commissioning survey: when faint gamma-ray sources are considered, pure positional coincidence is not significant enough for selecting counterparts and we need an additional physical criterion to pinpoint the right object. It can be radio spectral index, variability, polarization, or compactness, needing high angular resolution in SKA1-MID; timing studies can also reveal pulsars, which are often found from dedicated searches of unidentified gamma-ray sources. SKA will be the ideal instrument for investigating these characteristics in conjunction with CTA. (abridged)Comment: 12 pages, to be published in the proceedings of "Advancing Astrophysics with the Square Kilometre Array", PoS(AASKA14)15

Lesson from the habitat suitability models to evaluate the environmental of Pinus nigra Arnold and Pinus sylvesris L. in the Iberian Peninsula

PREDICT POTENTIAL DISTRIBUTION. Spatial and temporal evolution of the species under different climate scenarios. Generation of habitat suitability models (HSM) high degree of uncertainty and limitations. The importance of their validation has been stressed. In this work we discuss the present potential distribution of P. sylvestris and P. nigra in the Iberian Peninsula by using MaxEnt, and evaluate the influence of the different environmental variables. Our intention is to select a set of environmental variables that explains better their current distribution, to achieve the most accurate and reliable models. Then we project them to the past climatic conditions (21 to 0 kyrs BP), to evaluate the outputs with existing palaeo-ecological data

The milliarcsecond-scale jet of PKS 0735+178 during quiescence

We present polarimetric 5 GHz to 43 GHz VLBI observations of the BL Lacertae object PKS 0735+178, spanning March 1996 to May 2000. Comparison with previous and later observations suggests that the overall kinematic and structural properties of the jet are greatly influenced by its activity. Time intervals of enhanced activity, as reported before 1993 and after 2000 by other studies, are followed by highly superluminal motion along a rectilinear jet. In contrast the less active state in which we performed our observations, shows subluminal or slow superluminal jet features propagating through a twisted jet with two sharp bends of about 90 deg. within the innermost three-milliarcsecond jet structure. Proper motion estimates from the data presented here allow us to constrain the jet viewing angle to values < 9 deg., and the bulk Lorentz factor to be between 2 and 4.Comment: 11 pages, 12 figures. Accepted for publication in A&

Design and integration of WAAM technology and in situ monitoring system in a gantry machine

Wire arc additive manufacturing, WAAM, is a popular wire-feed additive manufacturing technology that creates components through the deposition of material layer-by-layer. WAAM has become a promising alternative to conventional machining due to its high deposition rate, environmental friendliness and cost-competitiveness. In this research work, an adaptation of a gantry machine with in-situ monitoring and a control system has been carried out, in order to expose the ability of the WAAM technology to fabricate complex-shaped parts. The retrofitting of the machine has been done in several layers called respectively hardware, control and software layers. For the validation of the implemented system, a stainless steel 316L demonstrator has been manufactured, and the required stages have been employed, including part design (CAD), process parameters selection, tool-path definition (CAM) and part manufacturing. This study has shown the feasibility of the adapted machine for additive manufacturing as a controlled process.The authors acknowledge the European Commission for support from project AMAZE (FP7-2012-NMP-ICT-FoF, project 313781) and the Basque Government for support from project EUSK-ADDI (Etorgai 2014)

Invasive breast cancer in Argentine women: Association between risk and prognostic factors with antigens of a peptidic and carbohydrate nature

Objective: In breast cancer, several tumor markers have been identified. The marker most extensively associated with breast cancer is MUC1. The objective of the study was to analyze prognostic and risk factors in relation to tumor markers in order to clarify breast cancer biology. A total of 349 primary tumor samples and lymph nodes from breast cancer patients were studied. Risk and prognostic factors were considered. An immunohistochemical approach was applied and an extensive statistical analysis was performed, including frequency analysis and analysis of variance. Correlation among variables was performed with principal component analysis. Results: All the antigens showed an increased expression according to tumor size increment; moreover, sialyl Lewis x expression showed a significant increase in relation to disease stage, whereas Tn and TF presented a positive tendency. Vascular invasion was related to sialyl Lewis x expression and number of metastatic lymph nodes. Taking into account risk factors, when a patient had at least one child, Lewis antigens diminished their expression. In relation to breastfeeding, sialyl Lewis x expression diminished, although its apical expression increased. Conclusion: Associations between MUC1 and carbohydrate antigens and risk and prognostic factors show the complexity of the cellular biological behavior that these antigens modulate in breast cancer.Facultad de Ciencias Médica

Invasive breast cancer in Argentine women: Association between risk and prognostic factors with antigens of a peptidic and carbohydrate nature

Objective: In breast cancer, several tumor markers have been identified. The marker most extensively associated with breast cancer is MUC1. The objective of the study was to analyze prognostic and risk factors in relation to tumor markers in order to clarify breast cancer biology. A total of 349 primary tumor samples and lymph nodes from breast cancer patients were studied. Risk and prognostic factors were considered. An immunohistochemical approach was applied and an extensive statistical analysis was performed, including frequency analysis and analysis of variance. Correlation among variables was performed with principal component analysis. Results: All the antigens showed an increased expression according to tumor size increment; moreover, sialyl Lewis x expression showed a significant increase in relation to disease stage, whereas Tn and TF presented a positive tendency. Vascular invasion was related to sialyl Lewis x expression and number of metastatic lymph nodes. Taking into account risk factors, when a patient had at least one child, Lewis antigens diminished their expression. In relation to breastfeeding, sialyl Lewis x expression diminished, although its apical expression increased. Conclusion: Associations between MUC1 and carbohydrate antigens and risk and prognostic factors show the complexity of the cellular biological behavior that these antigens modulate in breast cancer.Facultad de Ciencias Médica

Paleoclimatic and paleobiological correlations by mammal faunas from Southern America and SW Europe

Proceedings of the 1" R.C.A.N.S. Congress, Lisboa, October 1992The preliminary results of a research dealing with the study of global changes in the last 5 Ma by correlations of continental records between the Northern and the Southern Hemispheres (SW Europe and Argentina, respectively) are reported. The first analyses of the evolutionary patterns point out, in Argentina, two different turnover times: the first one is characterized by a high percentage of mammalautochthonous extinctions placed in the span of time between the last Chapadmalalan and the first Ensenadan faunas, around 2.5-2.3 Ma. It is possible to identify a high percentage of new immigrant genera from North America in the first turnover, while the second one, associated to the "last Pleistocene megafaunal extinctions", probably occurred at the beginning of the "Glacial Pleistocene", around 1.0-0.8 Ma. The oxygen isotope composition of phosphate from fossil mammal bones was measured to have a better climatic resolution from faunal elements of two hemispheres and to compare them by results as quantitative as possible. The preliminary efforts are brought out on fourteen deposits from SE Spain. Isotopic and chemical results strongly suggest the existence of a relation between the oxygen isotope composition in various skeletal components and the taphonomic processes of a single deposit. The variations of 0180 in the mammal teeth of Equidae from SE Spain suggest a shift towards a colder environment from the older one, Huelago, to more recent deposits, as well as from Venta Micena to Fuensanta in agreement with the transition from the Middle to the Upper Villafranchian, around 2.5 Ma, and the transition between the "Preglacial" to the "Glacial" Pleistocene, around 1.9-0.8 Ma

MUC1 positive cutaneous metastasis with transepidermal elimination from a breast carcinoma

Breast cancer is the most common cause of cutaneous metastases from internal malignancies. Generally, the neoplastic cells are located in the dermis or hypodermis, while a finding of transepidermal elimination on cutaneous metastases is exceptional. In this report we present a patient with perforating cutaneous metastases from breast cancer with mucin 1 expression. Cutaneous, bone, lung, and hepatic lesions were detected two years after the diagnosis of the primary tumor.Centro de Investigaciones Inmunológicas Básicas y Aplicada