Evaluasi USAbilitas Pada Aplikasi Program Simulasi Warna Batik

Saat ini penggunaan aplikasi berbasis komputer telah berbukti mampu mereduksi secara signifikan waktu yangdibutuhkan untuk merancang produk dibandingkan jika menggunakan metode konvensional. Hal ini cobaditerapkan pada industri batik oleh Rif'ah (2015) dengan mengembangkan Program Simulasi Warna Batik.Berdasarkan uji USAbility satisfaction yang telah dilakukan, aplikasi tersebut memiliki penerimaan oleh respondenrata-rata sebesar 3,87 dalam skala 1-5. Padahal menurut Nielsen (1993), suatu produk dikatakan memuaskan bilarata-rata nilainya 4 pada skala 1-5. Oleh karena itu aplikasi perangkat lunak ini masih perlu dikembangkan lebihlanjut. Metode yang digunakan pada penelitian ini adalah Heuristic Evaluation, yang merupakan salah satu metodedalam kajian USAbilitas. Usabilitas adalah atribut kualitatif yang menentukan seberapa mudah user menggunakanantarmuka suatu aplikasi. Berdasarkan penelitian yang telah dilakukan, masalah USAbilitas pada Program SimulasiWarna Batik yang terutama (48%) adalah berkenaan dengan “Match with user's task” (kesesuaian antaraketersediaan pada sistem dengan cara umum yang digunakan sesuai dengan persepsi pengguna). Selain itu,berdasarkan perhitungan persentase jumlah masalah USAbilitas yang ditemukan, diperoleh kesimpulan bahwajumlah evaluator sebanyak 15 orang berdasarkan model Nielsen (1992) masih cukup representatif

The Application of a Decision-making Approach Based on Fuzzy ANP and TOPSIS for Selecting a Strategic Supplier

Supplier selection becomes very important when used in the context of strategic partnerships because of the long-term orientation of the relationship. This paper describes the application of a decision-making approach for selecting a strategic partner (supplier). The approach starts with defining a set of criteria that fits the company's condition. In the next steps, a combination of fuzzy-ANP and TOPSIS methods is used to determine the weight for each criterion and rank all the alternatives. The application of the approach in an Indonesian manufacturing company showed that the three factors that got the highest weight were “geographical location”, “current operating performance”, and “reliability”. Geographical location got the highest weight because it affects many other factors such as reaction to changes in demand, after-sales service, and delivery lead-time. Application of the approach helps decision-makers to gain effectiveness and efficiency in the decision-making process because it facilitates them to express their group's collective preferences while also providing opportunities for members to express their individual preferences. Future research can be directed at combining qualitative and quantitative criteria to develop the best criteria and methods for the selection of the best suppliers based on fuzzy ANP and TOPSIS

Kinetic and thermodynamic study of oxidative degradation of acid yellow 17 dye by Fenton-like process: Effect of HCO3−, CO32−, Cl− and SO42− on dye degradation

We report here the degradation of AY-17 dye using Fenton-like process (H2O2/Fe3+). The maximum degradation (83%) of AY17 dye is achieved at pH 3 in 60 min, with optimum concentrations of AY 17 (0.06 mM), H2O2 (0.9 mM), and Fe2+ (0.06 mM). The scavenging effects of HCO3−, CO32−, Cl− and SO42− on dye degradation are also examined. The activation energy (Ea), activation enthalpy (rH*), and activation entropy (rS*) are calculated for the dye degradation using pseudo-first-order kinetics at various temperature.               KEY WORDS: Acid Yellow 17, H2O2/Fe3+, Fenton-like process, Oxidative degradation, Scavenging effects Bull. Chem. Soc. Ethiop. 2019, 33(2), 243-254.DOI: https://dx.doi.org/10.4314/bcse.v33i2.

The characteristic of PE (preeclampsia) complication at lupus on pregnancy

Background Indonesia had the serious challenge of highly maternal mortality over last ten years reflecting the real national health problem. There was 305 maternal death/100.000 deliveries, where 3 major possible cause of PE, PPH and infection persisted. Recently the new comer of diseases was standing tightly behind them: lupus on pregnancy. Material & Method This was a retrospective study from medical records.. Fifty-two cases of Lupus from 4592 pregnancy during 4 years (1.13%) have been observed in DR. Soetomo Teaching Hospital (tertiary hospital) Surabaya, Indonesia from January 2013 through December 2016. Results Sixteen cases of lupus were complicated by PE (30.7%), and 37.5% cases with Lupus Nephritis (that mostly showing increased serum creatinin level > 1.4 mg%). The maternal age were 25–34 years old (62.5%) and 62.5% were multigravida. Almost half cases (43.75%) got flare, leading to 25% early termination, while the remaining casesed (75%) were conservatively managed until 34 weeks gestation. Fetal outcome reported as 11 cases (68.75%) having birthweight > 2 kg, with 37.5% asphyxia (low apgar score). Discussion Pregnancy was discouraged in women affected by SLE, due to the disease becoming more aggresive during pregnancy and a poor pregnancy outcome was frequently reported. During pregnancy, the maternal immune system adapts to allow the growth of a semi-allogenic fetus. Significant immunological changes occur including suppression of type-2 helper cells (Th2), but the upregulation of Th1 cytokines in pregnancy may increase the risk for Th1-mediated diseases. The aboved concept was reflected at our study where most cases were sucessfully managed conservative until 34 weeks gestation and majority baby born with birthweight > 2 kg. Conclusions Our results suggest that lupus women are much more likely to develop worsening maternal spesifically preeclampsia and fetal outcomes when they become pregnant

Technical challenges of working with extracellular vesicles

Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with potential applications in diagnosis, prognosis and therapeutic guidance in most pathological conditions. These nanosized particles transmit signals determined by their protein, lipid, nucleic acid and sugar content, and the unique molecular pattern of EVs dictates the type of signal to be transmitted to recipient cells. However, their small sizes and the limited quantities that can usually be obtained from patient-derived samples pose a number of challenges to their isolation, study and characterization. These challenges and some possible options to overcome them are discussed in this review

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised