509 research outputs found
LFI 30 and 44 GHz receivers Back-End Modules
The 30 and 44 GHz Back End Modules (BEM) for the Planck Low Frequency
Instrument are broadband receivers (20% relative bandwidth) working at room
temperature. The signals coming from the Front End Module are amplified, band
pass filtered and finally converted to DC by a detector diode. Each receiver
has two identical branches following the differential scheme of the Planck
radiometers. The BEM design is based on MMIC Low Noise Amplifiers using GaAs
P-HEMT devices, microstrip filters and Schottky diode detectors. Their
manufacturing development has included elegant breadboard prototypes and
finally qualification and flight model units. Electrical, mechanical and
environmental tests were carried out for the characterization and verification
of the manufactured BEMs. A description of the 30 and 44 GHz Back End Modules
of Planck-LFI radiometers is given, with details of the tests done to determine
their electrical and environmental performances. The electrical performances of
the 30 and 44 GHz Back End Modules: frequency response, effective bandwidth,
equivalent noise temperature, 1/f noise and linearity are presented
Ancient DNA sheds light on the genetic origins of early Iron Age Philistines
The ancient Mediterranean port city of Ashkelon, identified as â}Philistine{â} during the Iron Age, underwent a marked cultural change between the Late Bronze and the early Iron Age. It has been long debated whether this change was driven by a substantial movement of people, possibly linked to a larger migration of the so-called {â}Sea Peoples.{â Here, we report genome-wide data of 10 Bronze and Iron Age individuals from Ashkelon. We find that the early Iron Age population was genetically distinct due to a European-related admixture. This genetic signal is no longer detectible in the later Iron Age population. Our results support that a migration event occurred during the Bronze to Iron Age transition in Ashkelon but did not leave a long-lasting genetic signature
The QUIJOTE experiment: project overview and first results
QUIJOTE (Q-U-I JOint TEnerife) is a new polarimeter aimed to characterize the
polarization of the Cosmic Microwave Background and other Galactic and
extragalactic signals at medium and large angular scales in the frequency range
10-40 GHz. The multi-frequency (10-20~GHz) instrument, mounted on the first
QUIJOTE telescope, saw first light on November 2012 from the Teide Observatory
(2400~m a.s.l). During 2014 the second telescope has been installed at this
observatory. A second instrument at 30~GHz will be ready for commissioning at
this telescope during summer 2015, and a third additional instrument at 40~GHz
is now being developed. These instruments will have nominal sensitivities to
detect the B-mode polarization due to the primordial gravitational-wave
component if the tensor-to-scalar ratio is larger than r=0.05.Comment: To appear in "Highlights of Spanish Astrophysics VIII", Proceedings
of the XI Scientific Meeting of the Spanish Astronomical Society, Teruel,
Spain (2014
Design, development and verification of the 30 and 44 GHz front-end modules for the Planck Low Frequency Instrument
We give a description of the design, construction and testing of the 30 and
44 GHz Front End Modules (FEMs) for the Low Frequency Instrument (LFI) of the
Planck mission to be launched in 2009. The scientific requirements of the
mission determine the performance parameters to be met by the FEMs, including
their linear polarization characteristics.
The FEM design is that of a differential pseudo-correlation radiometer in
which the signal from the sky is compared with a 4-K blackbody load. The Low
Noise Amplifier (LNA) at the heart of the FEM is based on indium phosphide High
Electron Mobility Transistors (HEMTs). The radiometer incorporates a novel
phase-switch design which gives excellent amplitude and phase match across the
band.
The noise temperature requirements are met within the measurement errors at
the two frequencies. For the most sensitive LNAs, the noise temperature at the
band centre is 3 and 5 times the quantum limit at 30 and 44 GHz respectively.
For some of the FEMs, the noise temperature is still falling as the ambient
temperature is reduced to 20 K. Stability tests of the FEMs, including a
measurement of the 1/f knee frequency, also meet mission requirements.
The 30 and 44 GHz FEMs have met or bettered the mission requirements in all
critical aspects. The most sensitive LNAs have reached new limits of noise
temperature for HEMTs at their band centres. The FEMs have well-defined linear
polarization characteristcs.Comment: 39 pages, 33 figures (33 EPS files), 12 tables. Planck LFI technical
papers published by JINST:
http://www.iop.org/EJ/journal/-page=extra.proc5/1748-022
Planck pre-launch status: calibration of the Low Frequency Instrument flight model radiometers
The Low Frequency Instrument (LFI) on-board the ESA Planck satellite carries
eleven radiometer subsystems, called Radiometer Chain Assemblies (RCAs), each
composed of a pair of pseudo-correlation receivers. We describe the on-ground
calibration campaign performed to qualify the flight model RCAs and to measure
their pre-launch performances. Each RCA was calibrated in a dedicated
flight-like cryogenic environment with the radiometer front-end cooled to 20K
and the back-end at 300K, and with an external input load cooled to 4K. A
matched load simulating a blackbody at different temperatures was placed in
front of the sky horn to derive basic radiometer properties such as noise
temperature, gain, and noise performance, e.g. 1/f noise. The spectral response
of each detector was measured as was their susceptibility to thermal variation.
All eleven LFI RCAs were calibrated. Instrumental parameters measured in these
tests, such as noise temperature, bandwidth, radiometer isolation, and
linearity, provide essential inputs to the Planck-LFI data analysis.Comment: 15 pages, 18 figures. Accepted for publication in Astronomy and
Astrophysic
Immunotherapy of lung cancer: An update
In Germany lung cancer is the leading cause of cancer-associated death in men. Surgery, chemotherapy and radiation may enhance survival of patients suffering from lung cancer but the enhancement is typically transient and mostly absent with advanced disease; eventually more than 90% of lung cancer patients will die of disease. New approaches to the treatment of lung cancer are urgently needed. Immunotherapy may represent one new approach with low toxicity and high specificity but implementation has been a challenge because of the poor antigenic characterization of these tumors and their ability to escape immune responses. Several different immunotherapeutic treatment strategies have been developed. This review examines the current state of development and recent advances with respect to non-specific immune stimulation, cellular immunotherapy ( specific and non-specific), therapeutic cancer vaccines and gene therapy for lung cancer. The focus is primarily placed on immunotherapeutic cancer treatments that are already in clinical trial or well progressed in preclinical studies. Although there seems to be a promising future for immunotherapy in lung cancer, presently there is not standard immunotherapy available for clinical routine
Planck pre-launch status: Low Frequency Instrument calibration and expected scientific performance
We give the calibration and scientific performance parameters of the Planck
Low Frequency Instrument (LFI) measured during the ground cryogenic test
campaign. These parameters characterise the instrument response and constitute
our best pre-launch knowledge of the LFI scientific performance. The LFI shows
excellent stability and rejection of instrumental systematic effects;
measured noise performance shows that LFI is the most sensitive instrument of
its kind. The set of measured calibration parameters will be updated during
flight operations through the end of the mission.Comment: Accepted for publications in Astronomy and Astrophysics. Astronomy &
Astrophysics, 2010 (acceptance date: 12 Jan 2010
- âŠ