Frames of mind

El artículo trata sobre las inteligencias múltiples. Breve repaso por la biografía de su autor Howard Gardner, el autor de la teoría de las inteligencias múltiples. Se explican las diferentes inteligencias: lingüística, musical, lógico-matemática, espacial, cinestésico-corporal, personal (intrapersonal e interpersonal) y naturalista, explicando los conceptos y con ejemplos de cada una de las inteligencias. Artículo de interés ya que en estos tiempos en los que se habla de innovación educativa, el autor es referente indispensable.The article is about multiple intelligences. Brief review of the biography of its author Howard Gardner, the author of the Theory of multiple intelligences. The different intelligences are explained: Linguistic, Musical, logical-mathematical, spatial, kinesthetic-bodily, personal (intrapersonal and interpersonal) and naturalist, explaining the concepts and with examples of each one of the intelligences. Article of interest since in these times in which we talk about educational innovation, the author is indispensable reference

Marketing digital y posicionamiento de marca de una empresa agroexportadora de banano orgánico de Piura, 2022

El presente informe tuvo como objetivo principal determinar la relación existente entre marketing digital y posicionamiento de marca de una empresa agroexportadora de banano orgánico de Piura 2022. El informe es de tipo aplicada; de enfoque cuantitativo, y el diseño fue correlacional, no experimental y transversal. Siendo la técnica la encuesta; y el instrumento fue un cuestionario. La muestra fue 30 posibles clientes, que fueron seleccionados mediante un muestreo no probabilístico por conveniencia. El informe se examinó mediante la estadística descriptiva inferencial, mediante un Software Estadístico SPSS versión 26. Se aplicó el coeficiente de correlación de Rho de Spearman para realizar el análisis de la hipótesis. Después del análisis se obtuvo los siguientes resultados de un nivel de significancia de 0.00, el cual permitió aceptar el H1; y tuvo un nivel de correlación positiva baja de 0.381*; demostrando que ha mayor incremento de marketing digital, mayor será el posicionamiento de marca; por consiguiente, se concluyó que existe relación significativa entre el marketing digital y el posicionamiento de marca siendo esta una correlación positiva débil

Maitake Pro4X has anti-cancer activity and prevents oncogenesis in BALBc mice

The understanding of the molecular mechanisms of the immune tolerance induced by the tumoral microenvironment is fundamental to prevent cancer development or to treat cancer patients using immunotherapy. Actually, there are investigations about "addressed-drugs" against cancer cells without affecting normal cells. It could be ideal to find selective and specific compounds that only recognize and destroy tumor cells without damaging the host normal cells. For thousands of years, mushrooms have been used for medicinal purposes because of their curative properties. D-Fraction, an extract of Maitake (from the edible Grifola frondosa mushroom), rich in β-glucans, exert notable effects in the immune system. Until now, some published articles suggest that Maitake D-Fraction could have anti-tumoral activity, prevent oncogenesis and metastasis in some tumor types. However, there are no clear data about Maitake D-Fraction action on breast cancer prevention and its exact molecular mechanisms are not yet elucidated. The experiments were performed employing 25 female BALBc mice that were treated with and without Maitake D-Fraction Pro4X or Maitake Standard for 15 days by daily intraperitoneal injection. After treatment period, all mice were implanted with murine tumor cells LM3 to induce mammary tumorigenesis. Animals were checked weekly and killed after 46 days of LM3 transplant; percentage of cancer prevention, rate of tumor growing, and overall survival were determined. Under dissection, the internal organs were evaluated histologically and genetically by RT-PCR. We found that 5 mg/kg per day of Maitake D-Fraction Pro4X, administered dairy during 15 days to BALBc mice was able to block more than 60% breast cancer development. However, Maitake Standard prevents oncogenesis in 26% to respect control. In this work, we found that Maitake D-Fraction Pro4X, administered to BALBc mice, prevents breast carcinogenesis, block tumor invasiveness, reduce angiogenesis, and increase overall survival.Fil: Roldan Deamicis, Agustina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires". Instituto de Investigaciones Biomédicas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas; ArgentinaFil: Alonso, Eliana Noelia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Centro de Recursos Naturales Renovables de la Zona Semiárida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona Semiárida; ArgentinaFil: Brie, Belen. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires". Instituto de Investigaciones Biomédicas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas; ArgentinaFil: Aguilera Braico, Diego Máximo. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires". Instituto de Investigaciones Biomédicas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas; ArgentinaFil: Balogh, Gabriela Andrea. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires". Instituto de Investigaciones Biomédicas. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas; Argentin

Abuso sexual infantil: la atemporalidad del trauma, consecuencias psíquicas y su incidencia en el cuerpo

El abuso sexual infantil es una de las formas más graves de violencia contra la infancia que atenta contra la integridad sexual de los/as niños/as y adolescentes ocasionando efectos devastadores en el psiquismo. Entendemos al abuso sexual infantil como un suceso traumático el cual muchas veces crece en la oscuridad del secreto y la impunidad donde el silencio intensifica las consecuencias y el ocultamiento las agrava. Este produce consecuencias psicológicas que frecuentemente no son asociadas al mismo pero que a largo plazo dejan huellas importantes en el psiquismo. Es en este contexto, donde el cuerpo se presenta como escenario de lo no dicho, de aquello no elaborado, traumático que irrumpe en el psiquismo trayendo consigo síntomas o patologías durante el desarrollo. Las consecuencias del abuso sexual infantil serán más graves cuanto mayor sea la magnitud del estímulo traumático, la implicación afectiva y la autoridad simbólica que el abusador represente, relacionado además con la prolongación en el tiempo de dichos sucesos y su impacto en la temporalidad psíquica. Las investigaciones demuestran que entre las patologías más frecuentes producto del abuso encontramos: trastornos de alimentación, depresión y trastornos por estrés postraumático.Sexual child abuse is one of the most serious forms of violence against childhood, which attempts against sexual integrity of children and teenagers, causing effects on their psyche. We understand child abuse as a traumatic event which, many times, happens in the darkness of secrecy and impunity, where silence intensified the consequences and hiding it makes them worse. Child abuse has psychological consequences that many times are not associated with it, but in long term leave important marks in the psyche. It is in this context where the body is presented as a scene of what is not said, of what is not elaborated, it is traumatic and bursts in the psyche carrying symptoms or pathologies during human development. The consequences of sexual child abuse will be more severe regarding how serious the traumatic stimulus is. The affective implication and the symbolic authority the abuser represents, also related to the duration of the events and their impact on the psychic temporary nature. The investigations show that among the most frequent pathologies resulting from child abuse, we find: eating disorders, depression and post-traumatic stress disorder.Facultad de Psicologí

Abuso sexual infantil: la atemporalidad del trauma, consecuencias psíquicas y su incidencia en el cuerpo

El abuso sexual infantil es una de las formas más graves de violencia contra la infancia que atenta contra la integridad sexual de los/as niños/as y adolescentes ocasionando efectos devastadores en el psiquismo. Entendemos al abuso sexual infantil como un suceso traumático el cual muchas veces crece en la oscuridad del secreto y la impunidad donde el silencio intensifica las consecuencias y el ocultamiento las agrava. Este produce consecuencias psicológicas que frecuentemente no son asociadas al mismo pero que a largo plazo dejan huellas importantes en el psiquismo. Es en este contexto, donde el cuerpo se presenta como escenario de lo no dicho, de aquello no elaborado, traumático que irrumpe en el psiquismo trayendo consigo síntomas o patologías durante el desarrollo. Las consecuencias del abuso sexual infantil serán más graves cuanto mayor sea la magnitud del estímulo traumático, la implicación afectiva y la autoridad simbólica que el abusador represente, relacionado además con la prolongación en el tiempo de dichos sucesos y su impacto en la temporalidad psíquica. Las investigaciones demuestran que entre las patologías más frecuentes producto del abuso encontramos: trastornos de alimentación, depresión y trastornos por estrés postraumático.Sexual child abuse is one of the most serious forms of violence against childhood, which attempts against sexual integrity of children and teenagers, causing effects on their psyche. We understand child abuse as a traumatic event which, many times, happens in the darkness of secrecy and impunity, where silence intensified the consequences and hiding it makes them worse. Child abuse has psychological consequences that many times are not associated with it, but in long term leave important marks in the psyche. It is in this context where the body is presented as a scene of what is not said, of what is not elaborated, it is traumatic and bursts in the psyche carrying symptoms or pathologies during human development. The consequences of sexual child abuse will be more severe regarding how serious the traumatic stimulus is. The affective implication and the symbolic authority the abuser represents, also related to the duration of the events and their impact on the psychic temporary nature. The investigations show that among the most frequent pathologies resulting from child abuse, we find: eating disorders, depression and post-traumatic stress disorder.Facultad de Psicologí

Victimization and Perception of Abuse in Adolescent and Young Homosexual and Heterosexual Couples in Spain

Currently, violence in adolescent and young couples has a significant social impact on young people’s physical and psychological health. However, the study of violence in homosexual couples must also be addressed. This research analyzes the levels of violent victimization and the perception of abuse in both homosexual and heterosexual couples. Participants’ ages ranged between 14 and 29 years (M = 20.14, SD = 3.464). We used The Dating Violence Questionnaire-Revised (CUIVNO-R), which was applied in two consecutive studies. The results indicate high levels of victimization, especially in the sample of homosexual participants. The scores generally show a low perception of couple violence but high victimization rates. The results of this study reveal the importance of the issue of violence in couples from minority groups and suggest that couple violence should not be understood as unidirectional, i.e., exclusively from men to women. These findings show the need for education in healthy relationships and consideration of different types of couples in these relationships.This work was supported by the European Regional Development Funds (European Union and Principality of Asturias) through the Science, Technology and Innovation Plan (AYUD/2021/51411) and the State Research Agency of the Ministry of Economic Affairs and Digital Transformation (MCI-21-PID2020-114736GB-100)

Abuso sexual infantil: la atemporalidad del trauma, consecuencias psíquicas y su incidencia en el cuerpo

El abuso sexual infantil es una de las formas más graves de violencia contra la infancia que atenta contra la integridad sexual de los/as niños/as y adolescentes ocasionando efectos devastadores en el psiquismo. Entendemos al abuso sexual infantil como un suceso traumático el cual muchas veces crece en la oscuridad del secreto y la impunidad donde el silencio intensifica las consecuencias y el ocultamiento las agrava. Este produce consecuencias psicológicas que frecuentemente no son asociadas al mismo pero que a largo plazo dejan huellas importantes en el psiquismo. Es en este contexto, donde el cuerpo se presenta como escenario de lo no dicho, de aquello no elaborado, traumático que irrumpe en el psiquismo trayendo consigo síntomas o patologías durante el desarrollo. Las consecuencias del abuso sexual infantil serán más graves cuanto mayor sea la magnitud del estímulo traumático, la implicación afectiva y la autoridad simbólica que el abusador represente, relacionado además con la prolongación en el tiempo de dichos sucesos y su impacto en la temporalidad psíquica. Las investigaciones demuestran que entre las patologías más frecuentes producto del abuso encontramos: trastornos de alimentación, depresión y trastornos por estrés postraumático.Sexual child abuse is one of the most serious forms of violence against childhood, which attempts against sexual integrity of children and teenagers, causing effects on their psyche. We understand child abuse as a traumatic event which, many times, happens in the darkness of secrecy and impunity, where silence intensified the consequences and hiding it makes them worse. Child abuse has psychological consequences that many times are not associated with it, but in long term leave important marks in the psyche. It is in this context where the body is presented as a scene of what is not said, of what is not elaborated, it is traumatic and bursts in the psyche carrying symptoms or pathologies during human development. The consequences of sexual child abuse will be more severe regarding how serious the traumatic stimulus is. The affective implication and the symbolic authority the abuser represents, also related to the duration of the events and their impact on the psychic temporary nature. The investigations show that among the most frequent pathologies resulting from child abuse, we find: eating disorders, depression and post-traumatic stress disorder.Facultad de Psicologí

Do humans spread zoonotic enteric bacteria in Antarctica?

Reports of enteric bacteria in Antarctic wildlife have suggested its spread from people to seabirds and seals, but evidence is scarce and fragmentary. We investigated the occurrence of zoonotic enteric bacteria in seabirds across the Antarctic and subantarctic region; for comparison purposes, in addition to seabirds, poultry in a subantarctic island was also sampled. Three findings suggest reverse zoonosis from humans to seabirds: the detection of a zoonotic Salmonella serovar (ser. Enteritidis) and Campylobacter species (e.g. C. jejuni), typical of human infections; the resistance of C. lari isolates to ciprofloxacin and enrofloxacin, antibiotics commonly used in human and veterinary medicine; and most importantly, the presence of C. jejuni genotypes mostly found in humans and domestic animals but rarely or never found in wild birds so far. We also show further spread of zoonotic agents among Antarctic wildlife is facilitated by substantial connectivity among populations of opportunistic seabirds, notably skuas (Stercorarius). Our results highlight the need for even stricter biosecurity measures to limit human impacts in Antarctica.info:eu-repo/semantics/acceptedVersio

Fragment C Domain of Tetanus Toxin Mitigates Methamphetamine Neurotoxicity and Its Motor Consequences in Mice

The C-terminal domain of the heavy chain of tetanus toxin (Hc-TeTx) is a nontoxic peptide with demonstrated in vitro and in vivo neuroprotective effects against striatal dopaminergic damage induced by 1-methyl-4-phenylpyridinium and 6-hydoxydopamine, suggesting its possible therapeutic potential in Parkinson's disease. Methamphetamine, a widely abused psychostimulant, has selective dopaminergic neurotoxicity in rodents, monkeys, and humans. This study was undertaken to determine whether Hc-TeTx might also protect against methamphetamine-induced dopaminergic neurotoxicity and the consequent motor impairment. For this purpose, we treated mice with a toxic regimen of methamphetamine (4mg/kg, 3 consecutive i.p. injections, 3 hours apart) followed by 3 injections of 40 ug/kg of Hc-TeTx into grastrocnemius muscle at 1, 24, and 48 hours post methamphetamine treatment. We found that Hc-TeTx significantly reduced the loss of dopaminergic markers tyrosine hydroxylase and dopamine transporter and the increases in silver staining (a well stablished degeneration marker) induced by methamphetamine in the striatum. Moreover, Hc-TeTx prevented the increase of neuronal nitric oxide synthase but did not affect microglia activation induced by methamphetamine. Stereological neuronal count in the substantia nigra indicated loss of tyrosine hydroxylase-positive neurons after methamphetamine that was partially prevented by Hc-TeTx. Importantly, impairment in motor behaviors post methamphetamine treatment were significantly reduced by Hc-TeTx. Here we demonstrate that Hc-TeTx can provide significant protection against acute methamphetamine-induced neurotoxicity and motor impairment, suggesting its therapeutic potential in methamphetamine abusers