Nonlinear Effects in Multicomponent Supramolecular Hydrogels

Multicomponent low molecular weight gels are useful for a range of applications. However, when mixing two components, both of which can independently form a gel, there are many potential scenarios. There is a limited understanding as to how to control and direct the assembly. Here, we focus on a pH-triggered two-component system. At high pH, colloidal structures are formed, and there is a degree of mixing of the two gelators. As the pH is decreased, there is a complex situation, where one gelator directs the assembly in a “sergeants and soldiers” manner. The second gelator is not fully incorporated, and the remainder forms an independent network. The result is that there is a nonlinear dependence on the final mechanical properties of the gels, with the storage or loss modulus being very dependent on the absolute ratio of the two components in the system

Pennsylvania Folklife Vol. 33, No. 3

• Moravian, Schwenkfelder, and American Log Construction • The Search for Our German Ancestors Continued: The Breunings of Mohringen • Where the Groundhog is King • The Louisiana Passport of Pennsylvania\u27s Charles Sealsfield • A Garden for the Friends of God : Religious Diversity in the Oley Valley to 1750https://digitalcommons.ursinus.edu/pafolklifemag/1103/thumbnail.jp

Orbital-free Bond Breaking via Machine Learning

Machine learning is used to approximate the kinetic energy of one dimensional diatomics as a functional of the electron density. The functional can accurately dissociate a diatomic, and can be systematically improved with training. Highly accurate self-consistent densities and molecular forces are found, indicating the possibility for ab-initio molecular dynamics simulations

Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2016)

This article lists the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in April 2016. Changes to virus taxonomy (the Universal Scheme of Virus Classification of the International Committee on Taxonomy of Viruses [ICTV]) now take place annually and are the result of a multi-stage process. In accordance with the ICTV Statutes (http://​www.​ictvonline.​org/​statutes.​asp), proposals submitted to the ICTV Executive Committee (EC) undergo a review process that involves input from the ICTV Study Groups (SGs) and Subcommittees (SCs), other interested virologists, and the EC. After final approval by the EC, proposals are then presented for ratification to the full ICTV membership by publication on an ICTV web site (http://​www.​ictvonline.​org/​) followed by an electronic vote. The latest set of proposals approved by the EC was made available on the ICTV website by January 2016 (https://​talk.​ictvonline.​org/​files/​proposals/​). A list of these proposals was then emailed on 28 March 2016 to the 148 members of ICTV, namely the EC Members, Life Members, ICTV Subcommittee Members (including the SG chairs) and ICTV National Representatives. Members were then requested to vote on whether to ratify the taxonomic proposals (voting closed on 29 April 2016)

Fractal dimensions of the Q-state Potts model for the complete and external hulls

Fortuin-Kastelyn clusters in the critical $Q$-state Potts model are conformally invariant fractals. We obtain simulation results for the fractal dimension of the complete and external (accessible) hulls for Q=1, 2, 3, and 4, on clusters that wrap around a cylindrical system. We find excellent agreement between these results and theoretical predictions. We also obtain the probability distributions of the hull lengths and maximal heights of the clusters in this geometry and provide a conjecture for their form.Comment: 9 pages 4 figure

Gut inflammation provides a respiratory electron acceptor for Salmonella.

Salmonella enterica serotype Typhimurium (S. Typhimurium) causes acute gut inflammation by using its virulence factors to invade the intestinal epithelium and survive in mucosal macrophages. The inflammatory response enhances the transmission success of S. Typhimurium by promoting its outgrowth in the gut lumen through unknown mechanisms. Here we show that reactive oxygen species generated during inflammation react with endogenous, luminal sulphur compounds (thiosulphate) to form a new respiratory electron acceptor, tetrathionate. The genes conferring the ability to use tetrathionate as an electron acceptor produce a growth advantage for S. Typhimurium over the competing microbiota in the lumen of the inflamed gut. We conclude that S. Typhimurium virulence factors induce host-driven production of a new electron acceptor that allows the pathogen to use respiration to compete with fermenting gut microbes. Thus the ability to trigger intestinal inflammation is crucial for the biology of this diarrhoeal pathogen

Mass drug administration and beyond : how can we strengthen health systems to deliver complex interventions to eliminate neglected tropical diseases?

Achieving the 2020 goals for Neglected Tropical Diseases (NTDs) requires scale-up of Mass Drug Administration (MDA) which will require long-term commitment of national and global financing partners, strengthening national capacity and, at the community level, systems to monitor and evaluate activities and impact. For some settings and diseases, MDA is not appropriate and alternative interventions are required. Operational research is necessary to identify how existing MDA networks can deliver this more complex range of interventions equitably. The final stages of the different global programmes to eliminate NTDs require eliminating foci of transmission which are likely to persist in complex and remote rural settings. Operational research is required to identify how current tools and practices might be adapted to locate and eliminate these hard-to-reach foci. Chronic disabilities caused by NTDs will persist after transmission of pathogens ceases. Development and delivery of sustainable services to reduce the NTD-related disability is an urgent public health priority. LSTM and its partners are world leaders in developing and delivering interventions to control vector-borne NTDs and malaria, particularly in hard-to-reach settings in Africa. Our experience, partnerships and research capacity allows us to serve as a hub for developing, supporting, monitoring and evaluating global programmes to eliminate NTDs

A Photometric Survey for Variables and Transits in the Field of Praesepe with KELT

The Kilodegree Extremely Little Telescope (KELT) project is a small aperture, wide-angle search for planetary transits of solar-type stars. In this paper, we present the results of a commissioning campaign with the KELT telescope to observe the open cluster Praesepe for 34 nights in early 2005. Lightcurves were obtained for 69,337 stars, out of which we identify 58 long period variables and 152 periodic variables. Sixteen of these are previously known as variable, yielding 194 newly discovered variable stars for which we provide properties and lightcurves. We also searched for planetary-like transits, finding four transit candidates. Follow-up observations indicate that two of the candidates are astrophysical false positives, with two candidates remaining as potential planetary transits.Comment: 45 pages, 16 figures. Submitted to AJ. PDF version with full resolution figures located at http://www.astronomy.ohio-state.edu/~pepper/kelt.pd