“For explorers by explorers”: A discursive analysis of cruise tourism in Norway

The Norwegian company Hurtigruten operates ships cruising along the Norwegian coast and has played an important role in tourism for over a century. This article provides a multimodal discourse analysis of the website advertising Hurtigruten’s most popular journey, drawing on a critical tourism studies approach. It aims to answer the question as to what central themes emerge in tourism discourse on Norway, targeted at an international audience. Central characteristics of tourism discourse (Dann 1996), i.e., strangerhood, conflict, authenticity, and playfulness, are shown to be crucial in the analysed material. The paper discusses the notion of authenticity as a performative strategy in the promotion of Norwegian cruise tourism. One central aim of this paper is finding out what and how the notion of “authentically Norwegian” is advertised. The results imply that these topics, and especially the notion of authenticity, are aligned with general tourism imaginaries, which are similar globally.         &nbsp

Rolle des humanen Apolipoprotein E im angeborenen Immunsystem

Research on age-related diseases like arteriosclerosis, dementia and age-related macular degeneration (AMD) is playing an important role in our steadily aging society. A conspicuous feature of many of these diseases is their association with the apolipoprotein E (ApoE). ApoE is an important protein in lipid metabolism and binds lipids as well as lipid receptors. Three isoforms, ApoE2, ApoE3 and ApoE4 differ only by one or two amino acids. Carriers of the ApoE2 isoform have an increased risk to develop AMD wheres the ApoE4 isoform is associated with a higher risk to develop dementia and arteriosclerosis. The cause of this is currently unknown. ApoE is found mainly in the deposits characteristic for the diseases. The deposits consist to a large extent of lipids, amyloid beta and cell debris, and form an activator surface for the complement system. An important role of the complement system is to eliminate body-borne waste products anti-inflammatorily, such as dead and damaged cells or modified lipids, with the help of regulators. However, in the case of the disease-related deposits, overactivation of the complement system, permanent inflammation and local damage occur. An association of the ApoE isoforms with the complement system has not yet been investigated. For the first time, this thesis shows that ApoE inhibits the classical pathway of the complement system at the level of the initial phase. Thus, ApoE is a new regulator of this pathway. All ApoE isoforms bind to the N-terminal domain between amino acids 139 and 152 to C1q. ApoE does not compete with the C1s-C1r-C1r-C1s tetramer to bind to C1q, but prevents the proteolytic cleavage of C2 and C4 by the C1 complex. According to that, ApoE has a double function: it acts as a lipid transport molecule and at the same time as a regulator of the classical complement pathway. Complement-activating surfaces, such as oxidized lipids which bind C1q, can thus be eliminated anti-inflammatorily with the aid of ApoE

Reciprocal circulation pattern of SARS-CoV-2 and influenza viruses during the influenza seasons 2019/2020 and 2020/2021 in the Bavarian Influenza Sentinel (Germany) – CORRIGENDUM

Peer Reviewe

PIAAC 2012: Die wichtigsten Ergebnisse im Überblick

Die Organisation für wirtschaftliche Zusammenarbeit und Entwicklung (OECD) untersucht mit dem Programme for the International Assessment of Adult Com-petencies (PIAAC) zentrale Grundkompetenzen in der erwachsenen Bevölkerung – wie die Lesekompetenz, die alltagsmathematische Kompetenz und technologiebasiertes Problemlösen –, von denen angenommen wird, dass sie für die erfolgreiche Teilhabe an der heutigen Gesellschaft von zentraler Bedeutung sind. Sie sind ein wichtiger Grundstein für die Entwicklung zahlreicher weiterer spezifischer Kompetenzen und Fertigkeiten. Mittels PIAAC sollen diese Schlüsselkompetenzen im Erwachsenenalter international verglichen werden. Der Fokus liegt hierbei auf der Bevölkerung im erwerbsfähigen Alter (16 bis 65 Jahre). Ergänzend hierzu werden in einigen Ländern, so auch in Deutschland, die Kompetenzen im höheren Alter untersucht, was insbesondere vor dem Hintergrund der Verschiebung des Renteneintrittsalters in Deutschland wichtige Informationen über den Kompetenzerhalt liefer

The Allen Telescope Array: The First Widefield, Panchromatic, Snapshot Radio Camera for Radio Astronomy and SETI

The first 42 elements of the Allen Telescope Array (ATA-42) are beginning to deliver data at the Hat Creek Radio Observatory in Northern California. Scientists and engineers are actively exploiting all of the flexibility designed into this innovative instrument for simultaneously conducting surveys of the astrophysical sky and conducting searches for distant technological civilizations. This paper summarizes the design elements of the ATA, the cost savings made possible by the use of COTS components, and the cost/performance trades that eventually enabled this first snapshot radio camera. The fundamental scientific program of this new telescope is varied and exciting; some of the first astronomical results will be discussed.Comment: Special Issue of Proceedings of the IEEE: "Advances in Radio Telescopes", Baars,J. Thompson,R., D'Addario, L., eds, 2009, in pres

The Allen Telescope Array Pi GHz Sky Survey I. Survey Description and Static Catalog Results for the Bootes Field

The Pi GHz Sky Survey (PiGSS) is a key project of the Allen Telescope Array. PiGSS is a 3.1 GHz survey of radio continuum emission in the extragalactic sky with an emphasis on synoptic observations that measure the static and time-variable properties of the sky. During the 2.5-year campaign, PiGSS will twice observe ~250,000 radio sources in the 10,000 deg^2 region of the sky with b > 30 deg to an rms sensitivity of ~1 mJy. Additionally, sub-regions of the sky will be observed multiple times to characterize variability on time scales of days to years. We present here observations of a 10 deg^2 region in the Bootes constellation overlapping the NOAO Deep Wide Field Survey field. The PiGSS image was constructed from 75 daily observations distributed over a 4-month period and has an rms flux density between 200 and 250 microJy. This represents a deeper image by a factor of 4 to 8 than we will achieve over the entire 10,000 deg^2. We provide flux densities, source sizes, and spectral indices for the 425 sources detected in the image. We identify ~100$ new flat spectrum radio sources; we project that when completed PiGSS will identify 10^4 flat spectrum sources. We identify one source that is a possible transient radio source. This survey provides new limits on faint radio transients and variables with characteristic durations of months.Comment: Accepted for publication in ApJ; revision submitted with extraneous figure remove