270 research outputs found

    HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth

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    Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that indicates the possibility of viral migration to the human vestibular labyrinth. Distribution of HSV-1 DNA was determined in geniculate ganglia, VGs, semicircular canals, and macula organs of 21 randomly obtained human temporal bones by nested PCR. Viral DNA was detected in 48% of the labyrinths, 62% of the VGs, and 57% of the geniculate ganglia. The potential significance of this finding is twofold: (1) Inflammation in VN could also involve the labyrinth and thereby cause acute unilateral vestibular deafferentation. (2) As benign paroxysmal positional vertigo often occurs in patients who have had VN, it could also be a sequel of viral labyrinthitis. Copyright (C) 2001 S. Karger AG, Basel

    Zeitgenössische Parallelberichte zum Chronicon Livoniae Heinrichs von Lettland

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    Digiteeritud Euroopa Regionaalarengu Fondi rahastusel, projekti "Eesti teadus- ja õppekirjandus" (2014-2020.12.03.21-0848) raames.https://www.ester.ee/record=b1088896*es

    Grundriss der Geschichte Liv-, Est- und Kurlands

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    http://tartu.ester.ee/record=b1795499~S1*es

    Phytol synthesis from geranylgeraniol in spinach chloroplasts

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    The reduction of /2-14C/-geranylgeranylpyrophosphate to phytylpyrophosphosphate is shown for the first time in chloroplasts. The esterification of exogenous /2-14C/-geranylgeranylpyrophosphate with endogenous chlorophyllide and the stepwise reduction of the pigment bound geranylgeraniol to phytol was also proved for spinach chloroplasts for the first time

    Akten und Rezesse der livländischen Ständetage : mit Unterstützung der baltischen Ritterschaften und Städte

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    Hauptsacht. 1.1907,1: Akten und Recesse der livländischen Ständetage. Band 1 (1304-1460), Erste Lieferung, Riga : Deubner, 1907. Hrsg. von Oskar Stavenhagen. Behandelt die Zeit 1304-1404. Band 1 (1304-1460), Zweite Lieferung (1404-1417), Riga : Jonck & Poliewsky, 1923. Bearb. von Oskar Stavenhagen und Leonid Arbusow jun. Band 2, (1460-1494), Erste Lieferung (1460-1466), Riga : Bruhns, 1934. Bearb. von Albert Bauer. Band 2, (1460-1494), Zweite Lieferung (1467 -1472), Riga : Bruhns, 1938. Bearb. von Albert Bauer

    Multicomponent Synthesis of 3,6-Dihydro-2H-1,3-thiazine-2-thiones

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    Non-fused 3,6-dihydro-2H-1,3-thiazine-2-thiones constitute a so far rather unexplored class of compounds, with the latest report dating back more than two decades. Thiazine-2-thiones contain an endocyclic dithiocarbamate group, which is often found in pesticides, in substrates for radical chemistry and in synthetic intermediates towards thioureas and amidines. We now report the multicomponent reaction (MCR) of in situ-generated 1-azadienes with carbon disulfide. With this reaction, a one-step protocol towards the potentially interesting 3,6-dihydro-2H-1,3-thiazine-2-thiones was established and a small library was synthesized
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