Somatic and cultural knowledge: drivers of a habitus-driven model of tacit knowledge acquisition

Purpose – The purpose of this paper is to identify and explain the role of individual learning and development in acquiring tacit knowledge in the context of the inexorable and intense continuous change (technological and otherwise) that characterizes our society today, and also to investigate the software (SW) sector, which is at the core of contemporary continuous change and is a paradigm of effective and intrinsic knowledge sharing (KS). This makes the SW sector unique and different from others where KS is so hard to implement. Design/methodology/approach – The study employed an inductive qualitative approach based on a multi-case study approach, composed of three successful SW companies in China. These companies are representative of the fabric of the sector, namely a small- and medium-sized enterprise, a large private company and a large state-owned enterprise. The fieldwork included 44 participants who were interviewed using a semi-structured script. The interview data were coded and interpreted following the Straussian grounded theory pattern of open coding, axial coding and selective coding. The process of interviewing was stopped when theoretical saturation was achieved after a careful process of theoretical sampling. Findings – The findings of this research suggest that individual learning and development are deemed to be the fundamental feature for professional success and survival in the continuously changing environment of the SW industry today. However, individual learning was described by the participants as much more than a mere individual process. It involves a collective and participatory effort within the organization and the sector as a whole, and a KS process that transcends organizational, cultural and national borders. Individuals in particular are mostly motivated by the pressing need to face and adapt to the dynamic and changeable environments of today’s digital society that is led by the sector. Software practitioners are continuously in need of learning, refreshing and accumulating tacit knowledge, partly because it is required by their companies, but also due to a sound awareness of continuous technical and technological changes that seem only to increase with the advances of information technology. This led to a clear theoretical understanding that the continuous change that faces the sector has led to individual acquisition of culture and somatic knowledge that in turn lay the foundation for not only the awareness of the need for continuous individual professional development but also for the creation of habitus related to KS and continuous learning. Originality/value – The study reported in this paper shows that there is a theoretical link between the existence of conducive organizational and sector-wide somatic and cultural knowledge, and the success of KS practices that lead to individual learning and development. Therefore, the theory proposed suggests that somatic and cultural knowledge are crucial drivers for the creation of habitus of individual tacit knowledge acquisition. The paper further proposes a habitus-driven individual development (HDID) Theoretical Model that can be of use to both academics and practitioners interested in fostering and developing processes of KS and individual development in knowledge-intensive organization

Extrinsic and intrinsic motivation for experience grounded tacit knowledge sharing in Chinese software organisations

Purpose – The purpose of this study is to identify and explain the role of individuals’ awareness and motivation in facilitating knowledge sharing (KS) in the real world of practice, as well as to establish areas of convergence between theory and practice that can be of use to both academics and practitioners involved in knowledge intensive organisations. Design/methodology/approach – This study used Grounded Theory (GT) as an inductive methodology to collect, analyse and interpret data from multiple case-studies. 44 participants from Chinese software organisations were selected on the basis of their role in SW design and development and were interviewed using a semi-structured interview script. The data analysis followed a Straussian approach to coding, which consists of open coding, axial coding and selective coding. The analysis focused on the impact of individuals’ awareness and motivation to share knowledge. Findings – The findings of this research show that the motivation for KS – a time consuming and demanding activity – is indeed related to awareness by managers and developers of the benefits of KS in their professional practice. Practitioners shared their experiences and tacit knowledge with others, partly because it was required by their companies, but also because they have a sound awareness of the need to share knowledge both inside and outside their organisations. Research limitations/implications – As a typical social science inductive study, this research is bounded by the context in which the theory proposed emerged from. Further research should be conducted into a richer variety of organisational and national contexts, as suggested by good theoretical sampling practice, which could provide further insights or contrasts. Originality/value – Despite a number of theoretical propositions found in the literature, there is a clear lack of implementation strategies and models that explain the role of awareness and motivation in facilitating KS in the world of practice. This issue of applicability of theoretical propositions is now recognised as one of the fundamental key issues in KS. This study provides new and practice grounded insights in this area and is of interest to both practitioners and theoreticians as it explains and bridges the individuals’ awareness and motivation for tacit KS

Nuclear Theory and Science of the Facility for Rare Isotope Beams

The Facility for Rare Isotope Beams (FRIB) will be a world-leading laboratory for the study of nuclear structure, reactions and astrophysics. Experiments with intense beams of rare isotopes produced at FRIB will guide us toward a comprehensive description of nuclei, elucidate the origin of the elements in the cosmos, help provide an understanding of matter in neutron stars, and establish the scientific foundation for innovative applications of nuclear science to society. FRIB will be essential for gaining access to key regions of the nuclear chart, where the measured nuclear properties will challenge established concepts, and highlight shortcomings and needed modifications to current theory. Conversely, nuclear theory will play a critical role in providing the intellectual framework for the science at FRIB, and will provide invaluable guidance to FRIB's experimental programs. This article overviews the broad scope of the FRIB theory effort, which reaches beyond the traditional fields of nuclear structure and reactions, and nuclear astrophysics, to explore exciting interdisciplinary boundaries with other areas. \keywords{Nuclear Structure and Reactions. Nuclear Astrophysics. Fundamental Interactions. High Performance Computing. Rare Isotopes. Radioactive Beams.Comment: 20 pages, 7 figure

Learning to live with nephrotic syndrome: experiences of adult patients and parents of children with nephrotic syndrome

People living with nephrotic syndrome (NS) need to develop an in-depth understanding of their condition in order to participate in treatment decisions, develop self-management skills and integrate illness into daily life. However, the learning needs of adult patients and parents of children with NS are unknown. We therefore explored patient and parent perspectives on learning needs related to NS as part of a larger study to develop a shared learning tool for NS

Genotype and clinical characteristics of patients with Wolfram syndrome and WFS1-related disorders

Objective: Wolfram syndrome (WFS) is an autosomal recessive disorder associated with juvenile-onset diabetes mellitus, optic atrophy, diabetes insipidus, and sensorineural hearing loss. We sought to elucidate the relationship between genotypic and phenotypic presentations of Wolfram syndrome which would assist clinicians in classifying the severity and prognosis of Wolfram syndrome more accurately.Approach: Patient data from the Washington University International Registry and Clinical Study for Wolfram Syndrome and patient case reports were analyzed to select for patients with two recessive mutations in the WFS1 gene. Mutations were classified as being either nonsense/frameshift variants or missense/in-frame insertion/deletion variants. Missense/in-frame variants were further classified as transmembrane or non-transmembrane based on whether they affected amino acid residues predicted to be in transmembrane domains of WFS1. Statistical analysis was performed using Wilcoxon rank-sum tests with multiple test adjustment applied via the Bonferonni correction.Results: A greater number of genotype variants correlated with earlier onset and a more severe presentation of Wolfram syndrome. Secondly, non-sense and frameshift variants had more severe phenotypic presentations than missense variants, as evidenced by diabetes mellitus and optic atrophy emerging significantly earlier in patients with two nonsense/frameshift variants compared with zero or one nonsense/frameshift variants. In addition, the number of transmembrane in-frame variants demonstrated a statistically significant dose-effect on age of onset of diabetes mellitus and optic atrophy among patients with either one or two in-frame variants.Summary/Conclusion: The results contribute to our current understanding of the genotype-phenotype relationship of Wolfram syndrome, suggesting that alterations in coding sequences result in significant changes in the presentation and severity of Wolfram. The impact of these findings is significant, as the results will aid clinicians in predicting more accurate prognoses and pave the way for personalized treatments for Wolfram syndrome

A Bimodal Science Measurements for Earth Remote Sensing on a 3U CubeSat Platform

Solar energetic events, which include solar flares and solar mass ejections affect the Earth\u27s atmosphere. While solar energetic events have been observed to influence the chemistry of the mesospheric ozone, a comprehensive collection of quantitative data detailing the frequency, energy, and intensity of these interactions with the mesosphere have, to our knowledge, not before been collected. High-energy charged particles from solar energetic events can ionize molecules found within the mesosphere, accelerating the formation rate of reactive hydrogen atoms and nitrogen oxides. This results in reactions that catalyze the conversion of ozone back into diatomic oxygen. The Variability in Atmosphere – Solar Energetic Event study (VIA-SEEs) mission intends to utilize a 3U-CubeSat in Low Earth Orbit (LEO) to establish a singular data set for the purpose of understanding the correlation between flux in solar energetic events and variability in total reactive nitrogen oxides (NOy) and ozone (O3) concentrations in the mesosphere. This mission intends to produce a unique data set using a bimodal measurement scheme involving two instruments – one Variability in Atmosphere (VIA) commercial-off-the-shelf spectrophotometer for measuring NOy and O3 concentrations, and one in-house designed and fabricated solid-state radiation detector for observing the energy and flux of solar energetic electrons and protons

Allergic Rhinitis and its Associated Co-Morbidities at Bugando Medical Centre in Northwestern Tanzania; A Prospective Review of 190 Cases.

Allergic rhinitis is one of the commonest atopic diseases which contribute to significant morbidity world wide while its epidemiology in Tanzania remains sparse. There was paucity of information regarding allergic rhinitis in our setting; therefore it was important to conduct this study to describe our experience on allergic rhinitis, associated co-morbidities and treatment outcome in patients attending Bugando Medical Centre. This was descriptive cross-sectional study involving all patients with a clinical diagnosis of allergic rhinitis at Bugando Medical Centre over a three-month period between June 2011 and August 2011. Data was collected using a pre-tested coded questionnaire and analyzed using SPSS statistical computer software version 17.0. A total of 190 patients were studied giving the prevalence of allergic rhinitis 14.7%. The median age of the patients was 8.5 years. The male to female ratio was 1:1. Adenoid hypertrophy, tonsillitis, hypertrophy of inferior turbinate, nasal polyps, otitis media and sinusitis were the most common co-morbidities affecting 92.6% of cases and were the major reason for attending hospital services. Sleep disturbance was common in children with adenoids hypertrophy (χ2 = 28.691, P = 0.000). Allergic conjunctivitis was found in 51.9%. The most common identified triggers were dust, strong perfume odors and cold weather (P < 0.05). Strong perfume odors affect female than males (χ2 = 4.583, P = 0.032). In this study family history of allergic rhinitis was not a significant risk factor (P =0.423). The majority of patients (68.8%) were treated surgically for allergic rhinitis co morbidities. Post operative complication and mortality rates were 2.9% and 1.6% respectively. The overall median duration of hospital stay of in-patients was 3 days (2 - 28 days). Most patients (98.4%) had satisfactory results at discharge. The study shows that allergic rhinitis is common in our settings representing 14.7% of all otorhinolaryngology and commonly affecting children and adolescent. Sufferers seek medical services due to co-morbidities of which combination of surgical and medical treatment was needed. High index of suspicions in diagnosing allergic rhinitis and early treatment is recommended

Influence of continuous exposure to gaseous ozone on the quality of red bell peppers, cucumbers and zucchini

The effect of continuous exposure to ozone on quality changes during the storage of red bell peppers, cucumbers and zucchini was investigated. Peppers were stored at 14 °C and were exposed to ozone at 0.1 and 0.3 μmol mol−1, while cucumbers and zucchini were stored at 12 and 8 °C, respectively, and exposed to ozone at 0.1 μmol mol−1. The content of fructose (2.75 g/100 g FW) and glucose (2.00 g/100 g FW) in red bell peppers exposed to ozone at 0.1 μmol mol−1 was increased by 8 and 7%, respectively, when compared to controls. Continuous exposure to ozone at 0.3 μmol mol−1, on the other hand, had no effect on fructose (2.52 g/100 g FW) and glucose (1.88 g/100 g FW) content. The content of vitamin C was significantly enhanced in red bell peppers exposed to ozone at 0.1 and 0.3 μmol mol−1 after 7 d of storage, however, this effect was not maintained. After 14 d, vitamin C content in peppers exposed to ozone at 0.1 μmol mol−1 was not significantly different from the control, whereas it was reduced at 0.3 μmol mol−1. Total phenolics content was increased in peppers exposed to ozone at 0.1 μmol mol−1, but was unaffected at 0.3 μmol mol−1. Continuous exposure of red bell peppers to ozone at 0.1 and 0.3 μmol mol−1 had no significant effect on weight loss, texture and colour. In cucumbers and zucchini, continuous exposure to ozone at 0.1 μmol mol−1 reduced weight loss by more than 40% and improved texture maintenance, while having no significant effect on their biochemistry. The findings from this study suggest that continuous exposure to ozone at 0.1 μmol mol−1 is a promising method for shelf-life extension of cucumbers and zucchini. Even though in red bell peppers continuously exposed to ozone at 0.1 μmol mol−1 sugars and phenolics content was increased, further work is still needed to better understand the exact mechanism of ozone action and its potential for the industrial use

Evaluation of qPCR-Based Assays for Leprosy Diagnosis Directly in Clinical Specimens

The increased reliability and efficiency of the quantitative polymerase chain reaction (qPCR) makes it a promising tool for performing large-scale screening for infectious disease among high-risk individuals. To date, no study has evaluated the specificity and sensitivity of different qPCR assays for leprosy diagnosis using a range of clinical samples that could bias molecular results such as difficult-to-diagnose cases. In this study, qPCR assays amplifying different M. leprae gene targets, sodA, 16S rRNA, RLEP and Ag 85B were compared for leprosy differential diagnosis. qPCR assays were performed on frozen skin biopsy samples from a total of 62 patients: 21 untreated multibacillary (MB), 26 untreated paucibacillary (PB) leprosy patients, as well as 10 patients suffering from other dermatological diseases and 5 healthy donors. To develop standardized protocols and to overcome the bias resulted from using chromosome count cutoffs arbitrarily defined for different assays, decision tree classifiers were used to estimate optimum cutoffs and to evaluate the assays. As a result, we found a decreasing sensitivity for Ag 85B (66.1%), 16S rRNA (62.9%), and sodA (59.7%) optimized assay classifiers, but with similar maximum specificity for leprosy diagnosis. Conversely, the RLEP assay showed to be the most sensitive (87.1%). Moreover, RLEP assay was positive for 3 samples of patients originally not diagnosed as having leprosy, but these patients developed leprosy 5–10 years after the collection of the biopsy. In addition, 4 other samples of patients clinically classified as non-leprosy presented detectable chromosome counts in their samples by the RLEP assay suggesting that those patients either had leprosy that was misdiagnosed or a subclinical state of leprosy. Overall, these results are encouraging and suggest that RLEP assay could be useful as a sensitive diagnostic test to detect M. leprae infection before major clinical manifestations