Studies on flavonoid metabolism. Metabolism of (+)-[(14)C]catechin in the rat and guinea pig

1. The fate of (+)-[U-(14)C]catechin and (+)-[ring A-(14)C]catechin has been studied in the guinea pig and rat. 2. (+)-[U-(14)C]Catechin was shown to give rise to labelled phenolic acids, labelled phenyl-γ-valerolactones and (14)CO(2). 3. (+)-[ring A-(14)C]-Catechin did not give rise to labelled phenolic acids, but labelled phenyl-γ-valerolactones were detected together with a higher proportion of (14)CO(2). 4. Administered [(14)C]δ-(3-hydroxyphenyl)-γ-valerolactone gave rise to labelled m-hydroxyphenylpropionic acid in the rat whereas administered [(14)C]m-hydroxyphenylpropionic acid gave rise to a compound yielding labelled m-hydroxybenzoic acid on hydrolysis. 5. The distribution of radioactivity in the urine and faeces of (+)-[(14)C]catechin-fed animals is described; a high proportion of residual radioactivity was found in urine that had been exhaustively extracted with diethyl ether

Measurement of the top quark pair production cross-section with ATLAS in the single lepton channel

A measurement of the production cross-section for top quark pairs (View the MathML source) in pp collisions at View the MathML source is presented using data recorded with the ATLAS detector at the Large Hadron Collider. Events are selected in the single lepton topology by requiring an electron or muon, large missing transverse momentum and at least three jets. With a data sample of 35 pb−1, two different multivariate methods, one of which uses b -quark jet identification while the other does not, use kinematic variables to obtain cross-section measurements of View the MathML source and View the MathML source respectively. The two measurements are in agreement with each other and with QCD calculations. The first measurement has a better a priori sensitivity and constitutes the main result of this Letter