Clifford algebras and universal sets of quantum gates

In this paper is shown an application of Clifford algebras to the construction of computationally universal sets of quantum gates for $n$-qubit systems. It is based on the well-known application of Lie algebras together with the especially simple commutation law for Clifford algebras, which states that all basic elements either commute or anticommute.Comment: 4 pages, REVTeX (2 col.), low-level language corrections, PR

On the size of the smallest scales in cosmic string networks

We present a method for the calculation of the gravitational back reaction cutoff on the smallest scales of cosmic string networks taking into account that not all modes on strings interact with all other modes. This results in a small scale structure cutoff that is sensitive to the initial spectrum of perturbations present on strings. From a simple model, we compute the cutoffs in radiation- and matter-dominated universes.Comment: 4 pages, revte

Risk factors associated with lambing traits

peer-reviewedThis article was first published in Animal (2016), 10:1, pp 89–95, © The Animal Consortium 2015The objective of this study was to establish the risk factors associated with both lambing difficulty and lamb mortality in the Irish sheep multibreed population. A total of 135 470 lambing events from 42 675 ewes in 839 Irish crossbred and purebred flocks were available. Risk factors associated with producer-scored ewe lambing difficulty score (scale of one (no difficulty) to four (severe difficulty)) were determined using linear mixed models. Risk factors associated with the logit of the probability of lamb mortality at birth (i.e. binary trait) were determined using generalised estimating equations. For each dependent variable, a series of simple regression models were developed as well as a multiple regression model. In the simple regression models, greater lambing difficulty was associated with quadruplet bearing, younger ewes, of terminal breed origin, lambing in February; for example, first parity ewes experienced greater (P7.0 kg) birth weights, quadruplet born lambs and lambs that experienced a more difficult lambing (predicted probability of death for lambs that required severe and veterinary assistance of 0.15 and 0.32, respectively); lambs from dual-purpose breeds and born to younger ewes were also at greater risk of mortality. In the multiple regression model, the association between ewe parity, age at first lambing, year of lambing and lamb mortality no longer persisted. The trend in solutions of the levels of each fixed effect that remained associated with lamb mortality in the multiple regression model, did not differ from the trends observed in the simple regression models although the differential in relative risk between the different lambing difficulty scores was greater in the multiple regression model. Results from this study show that many common flock- and animal-level factors are associated with both lambing difficulty and lamb mortality and management of different risk category groups (e.g. scanned litter sizes, ewe age groups) can be used to appropriately manage the flock at lambing to reduce their incidence

Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.

The fungal pathogen Candida glabrata has emerged as a major health threat since it readily acquires resistance to multiple drug classes, including triazoles and/or echinocandins. Thus far, cellular mechanisms promoting the emergence of resistance to multiple drug classes have not been described in this organism. Here we demonstrate that a mutator phenotype caused by a mismatch repair defect is prevalent in C. glabrata clinical isolates. Strains carrying alterations in mismatch repair gene MSH2 exhibit a higher propensity to breakthrough antifungal treatment in vitro and in mouse models of colonization, and are recovered at a high rate (55% of all C. glabrata recovered) from patients. This genetic mechanism promotes the acquisition of resistance to multiple antifungals, at least partially explaining the elevated rates of triazole and multi-drug resistance associated with C. glabrata. We anticipate that identifying MSH2 defects in infecting strains may influence the management of patients on antifungal drug therapy

Radioactive stents delay but do not prevent in-stent neointimal hyperplasia

BACKGROUND: Restenosis after conventional stenting is almost exclusively caused by neointimal hyperplasia. Beta-particle-emitting radioactive stents decrease in-stent neointimal hyperplasia at 6-month follow-up. The purpose of this study was to evaluate the 1-year outcome of (32)P radioactive stents with an initial activity of 6 to 12 microCi using serial quantitative coronary angiography and volumetric ECG-gated 3D intravascular ultrasound (IVUS). METHODS AND RESULTS: Of 40 patients undergoing initial stent implantation, 26 were event-free after the 6-month follow-up period and 22 underwent repeat catheterization and IVUS at 1 year; they comprised half of the study population. Significant luminal deterioration was observed within the stents between 6 months and 1 year, as evidenced by a decrease in the angiographic minimum lumen diameter (-0.43+/-0.56 mm; P:=0.028) and in the mean lumen diameter in the stent (-0.55+/-0. 63 mm; P:=0.001); a significant increase in in-stent neointimal hyperplasia by IVUS (18.16+/-12.59 mm(3) at 6 months to 27.75+/-11. 99 mm(3) at 1 year; P:=0.001) was also observed. Target vessel revascularization was performed in 5 patients (23%). No patient experienced late occlusion, myocardial infarction, or death. By 1 year, 21 of the initial 40 patients (65%) remained event-free. CONCLUSIONS: Neointimal proliferation is delayed rather than prevented by radioactive stent implantation. Clinical outcome 1 year after the implantation of stents with an initial activity of 6 to 12 microCi is not favorable when compared with conventional stenting

The 4 Ms Chandra Deep Field-South number counts apportioned by source class : pervasive active galactic nuclei and the ascent of normal galaxies

We present 0.5-2 keV, 2-8 keV, 4-8 keV, and 0.5-8 keV (hereafter soft, hard, ultra-hard, and full bands, respectively) cumulative and differential number-count (log N-log S) measurements for the recently completed ≈4 Ms Chandra Deep Field-South (CDF-S) survey, the deepest X-ray survey to date. We implement a new Bayesian approach, which allows reliable calculation of number counts down to flux limits that are factors of ≈1.9-4.3 times fainter than the previously deepest number-count investigations. In the soft band (SB), the most sensitive bandpass in our analysis, the ≈4 Ms CDF-S reaches a maximum source density of ≈27,800 deg-2. By virtue of the exquisite X-ray and multiwavelength data available in the CDF-S, we are able to measure the number counts from a variety of source populations (active galactic nuclei (AGNs), normal galaxies, and Galactic stars) and subpopulations (as a function of redshift, AGN absorption, luminosity, and galaxy morphology) and test models that describe their evolution. We find that AGNs still dominate the X-ray number counts down to the faintest flux levels for all bands and reach a limiting SB source density of ≈14,900 deg-2, the highest reliable AGN source density measured at any wavelength. We find that the normal-galaxy counts rise rapidly near the flux limits and, at the limiting SB flux, reach source densities of ≈12,700 deg-2 and make up 46% ± 5% of the total number counts. The rapid rise of the galaxy counts toward faint fluxes, as well as significant normal-galaxy contributions to the overall number counts, indicates that normal galaxies will overtake AGNs just below the ≈4 Ms SB flux limit and will provide a numerically significant new X-ray source population in future surveys that reach below the ≈4 Ms sensitivity limit. We show that a future ≈10 Ms CDF-S would allow for a significant increase in X-ray-detected sources, with many of the new sources being cosmologically distant (z >~ 0.6) normal galaxies

X-ray Spectroscopy and Variability of AGN Detected in the 2 Ms Chandra Deep Field-North Survey

We investigate the nature of the faint X-ray source population through X-ray spectroscopy and variability analyses of 136 AGN detected in the 2 Ms Chandra Deep Field-North survey with > 200 background-subtracted 0.5-8.0 keV counts [F(0.5-8.0 keV)=(1.4-200)e-15 erg cm^{-2} s^{-1}]. Our preliminary spectral analyses yield median spectral parameters of Gamma=1.61 and intrinsic N_H=6.2e21 cm^{-2} (z=1 assumed when no redshift available) when the AGN spectra are fitted with a simple absorbed power-law model. However, considerable spectral complexity is apparent (e.g., reflection, partial covering) and must be taken into account to model the data accurately. Moreover, the choice of spectral model (i.e., free vs. fixed photon index) has a pronounced effect on the derived N_H distribution and, to a lesser extent, the X-ray luminosity distribution. Ten of the 136 AGN (~7%) show significant Fe Kalpha emission-line features with equivalent widths in the range 0.1-1.3 keV. Two of these emission-line AGN could potentially be Compton thick (i.e., Gamma < 1.0 and large Fe Kalpha equivalent width). Finally, we find that 81 (~60%) of the 136 AGN show signs of variability, and that this fraction increases significantly (~80-90%) when better photon statistics are available.Comment: Submitted to Advances in Space Research for New X-ray Results from Clusters of Galaxies and Black Holes (Oct 2002; Houston, TX), eds. C. Done, E.M. Puchnarewicz, M.J. Ward. Requires cospar.sty (6 pgs, 10 figs

Black Hole Growth Is Mainly Linked to Host-galaxy Stellar Mass Rather Than Star Formation Rate

We investigate the dependence of black-hole accretion rate (BHAR) on host-galaxy star formation rate (SFR) and stellar mass (M∗) in the CANDELS/GOODS-South field in the redshift range of 0.5≤z<2.0. Our sample consists of ≈18000 galaxies, allowing us to probe galaxies with 0.1≲SFR≲100 M⊙ yr−1 and/or 108≲M∗≲1011 M⊙. We use sample-mean BHAR to approximate long-term average BHAR. Our sample-mean BHARs are derived from the Chandra Deep Field-South 7 Ms observations, while the SFRs and M∗ have been estimated by the CANDELS team through SED fitting. The average BHAR is correlated positively with both SFR and M∗, and the BHAR-SFR and BHAR-M∗ relations can both be described acceptably by linear models with a slope of unity. However, BHAR appears to be correlated more strongly with M∗ than SFR. This result indicates that M∗ is the primary host-galaxy property related to black-hole growth, and the apparent BHAR-SFR relation is largely a secondary effect due to the star-forming main sequence. Among our sources, massive galaxies (M∗≳1010M⊙) have significantly higher BHAR/SFR ratios than less-massive galaxies, indicating the former have higher black-hole fueling efficiency and/or higher SMBH occupation fraction than the latter. Our results can naturally explain the observed proportionality between MBH and M∗ for local giant ellipticals, and suggest their MBH/M∗ is higher than that of local star-forming galaxies. Among local star-forming galaxies, massive systems might have higher MBH/M∗ compared to dwarfs

Effects of the field modulation on the Hofstadter's spectrum

We study the effect of spatially modulated magnetic fields on the energy spectrum of a two-dimensional (2D) Bloch electron. Taking into account four kinds of modulated fields and using the method of direct diagonalization of the Hamiltonian matrix, we calculate energy spectra with varying system parameters (i.e., the kind of the modulation, the relative strength of the modulated field to the uniform background field, and the period of the modulation) to elucidate that the energy band structure sensitively depends on such parameters: Inclusion of spatially modulated fields into a uniform field leads occurrence of gap opening, gap closing, band crossing, and band broadening, resulting distinctive energy band structure from the Hofstadter's spectrum. We also discuss the effect of the field modulation on the symmetries appeared in the Hofstadter's spectrum in detail.Comment: 7 pages (in two-column), 10 figures (including 2 tables

X-Ray Spectral Constraints for z ≈ 2 Massive Galaxies: The Identification of Reflection-dominated Active Galactic Nuclei

We use the 4 Ms Chandra Deep Field-South (CDF-S) survey to place direct constraints on the ubiquity of z 2 heavily obscured active galactic nuclei (AGNs) in K 10 keV observatories. On the basis of these analyses, we estimate the space density for typical (intrinsic X-ray luminosities of L 2-10 keV 1043 erg s–1) heavily obscured and Compton-thick AGNs at z 2. Our space-density constraints are conservative lower limits but they are already consistent with the range of predictions from X-ray background models