DESENVOLVIMENTO DE LINFOMA EM CÃO COM LEISHMANIOSE VISCERAL

Canine lymphoma results in the uncontrolled proliferation of malignant lymphocytes originating from lymphoreticular cells, mainly affecting lymphoid organs such as lymph nodes, liver, bone marrow and spleen. It is considered the most common lymphoproliferative neoplasia, which can be classified according to its anatomical location in the forms: multicentric, alimentary, cutaneous, thymic and extranodal. The objective of this study was to report the clinical aspects of lymphoma in a dog with canine visceral leishmaniasis, as well as to emphasize the importance of complementary tests to obtain an   accurate diagnosis in cases of comorbidities. A 5-year-old male Doberman dog, weighing 30 kg, was attended at the Metropolitan Veterinary Hospital of Caucaia (HVM), presenting with edema in the left anterior limb, hypocorous mucosae, halitosis, dehydration, fever, peeling and skin lesion, onychogrifose, anorexia, subcutaneous nodules and palpable lymph nodes, and the left axillary lymph node was markedly enlarged. According to the anamnesis and physical examination, hematological, biochemical (renal and hepatic reviews) tests, serology for Calazar, chest X-ray and lymph node cytology were requested. The cytology result indicated a neoplastic picture suggestive of lymphoma and the serology was reactive for leishmaniasis. The patient was referred to the oncologist in order to establish the best therapeutic form for the lymphoma, thus giving the appropriate prognosis, but the animal died due to its progressive clinical condition before starting the treatment. It is concluded that the clinical signs together with the complementary exams are important in obtaining the diagnosis for lymphoma and leishmaniasis, assuming that these diseases can affect the animal in isolation or in a joint manner.O linfoma canino resulta na proliferação descontrolada dos linfócitos malignos originados pelas células linforreticulares, acometendo principalmente os órgãos linfóides que são os linfonodos, fígado, medula óssea e baço. É considerado a neoplasia linfoproliferativa mais comum, a qual pode ser classificada de acordo com a sua localização anatômica nas formas: multicêntrico, alimentar, cutâneo, tímico e extranodal. O objetivo desse trabalho foi relatar os aspectos clínicos do linfoma em um cão portador da Leishmaniose visceral canina, bem como ressaltar a importância dos exames complementares para a obtenção de um diagnóstico preciso em casos de co-morbidade. Foi atendido no Hospital Veterinário Metropolitano de Caucaia (HVM), um canino da raça Doberman, macho, 5 anos de idade, pesando 30 quilos, apresentando edemaciação no membro anterior esquerdo, mucosas hipocoradas, halitose, desidratação, febre, descamação e lesão na pele, onicogrifose, anorexia, nódulos subcutâneo e linfonodos palpáveis, sendo que o linfonodo axilar esquerdo estava acentuadamente aumentado. De acordo com a anamnese e exame físico, foram solicitados os exames hematológicos, bioquímicos (análises renal e hepática), sorologia para Calazar, radiografia de tórax e citologia do linfonodo. O resultado da citologia indicou um quadro neoplásico sugestivo de linfoma e a sorologia foi reagente para leishmaniose. O paciente foi encaminhado para o oncologista com o intuito de o especialista instituir a melhor forma terapêutica para o linfoma, dando assim o prognóstico adequado, porém o animal veio a óbito devido sua progressiva condição clínica antes de iniciar o tratamento. Conclui-se que os sinais clínicos juntamente com os exames complementares são importantes na obtenção do diagnóstico para o linfoma e leishmaniose, partindo do princípio que essas enfermidades podem acometer o animal de forma isolada ou conjunta

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

A efetividade do processo, o contraditório e a ampla defesa : conciliação dos princípios nas ações cautelares

Tem como escopo buscar argumentos conciliatórios com os princípios dos direitos e garantias fundamentais para que a busca da efetividade não prejudique o contraditório e a ampla defesa e, por outro lado, para que a supervalorização desses dois últimos não prejudique a efetividade da concretização do acesso à justiça

Subcontratación y precarización del trabajo. Un estudio comparativo de la norma laboral brasileña y española

[ES] Tesis doctoral sobre la subcontratación y precarización del trabajo, en la que se realiza un estudio comparativo de la norma laboral brasileña y española.[EN] Doctoral thesis on outsourcing and casualization of labor, in which a comparative study of Brazilian and Spanish labor standard

Run, hide, or fight: anti-predation strategies in endangered red-nosed cuxiú (Chiropotes albinasus, Pitheciidae) in southeastern Amazonia

Although primate predation is rarely observed, a series of primate anti-predation strategies have been described. Energetic costs of such strategies can vary from high-cost mobbing, via less costly alarm calling, to low-cost furtive concealment. Here we report the anti-predation strategies of red-nosed cuxiú, Chiropotes albinasus, based on direct observations from four study sites in southeastern Brazilian Amazonia. Over a collective period of 1255 fieldwork hours, we observed nine direct interactions between raptors (all potential predators) and red-nosed cuxiús. Of these, one (11%) resulted in predation. Raptors involved were: Harpia harpyja (four events), Leucopternis sp. (two events), Spizaëtus tyrannus (one event), and unidentified large raptors (two events). Predation attempts occurred in flooded-forest and terra firme rainforest, were directed at both adult and non-adult cuxiús, and involved both adult and juvenile raptors. Anti-predation strategies adopted by the cuxiús included: (1) group defence and mobbing behaviour (two occasions), (2) dropping into dense sub-canopy (seven occasions), (3) alarm calling (eight occasions), and (4) fleeing to, and hiding in, dense vegetation (eight occasions). During each encounter at least two of these behaviours were recorded. These are the first published records of predation, predation attempts, and anti-predator behaviour involving red-nosed cuxiú. © 2017, Japan Monkey Centre and Springer Japan

Predictors of Coronary Artery Obstructive Disease in Acute Pulmonary Edema of Unclear Origin

<div><p>Abstract Background: Cardiogenic Acute Pulmonary Edema (APE) is considered one of the main medical emergencies, and it is the extreme manifestation of acute heart failure. The main etiology of heart failure is ischemic heart disease. To date, the definition of ischemic etiology in acute pulmonary edema was based on criteria such as: clinical history of ischemic heart disease, noninvasive examinations and, in other patients, coronary angiography. Classified as such, ischemic heart disease has been shown to be its main etiology. The high prevalence between these two diseases was evaluated, but not by the exclusive angiographic criterion, the gold standard of this pathology and the reason of this study. Objective: To evaluate the predictors of obstructive coronary artery disease in patients with acute pulmonary edema of unclear origin. Method: Patients admitted to a cardiovascular disease referral emergency unit were recruited to undergo coronary angiography if the acute pulmonary edema etiology was not adequately elucidated. Obstructive coronary disease was considered if at least one epicardial vessel had 70% of occlusion. Results: Obstructive coronary disease was classified by coronary angiography in 149 consecutively evaluated patients, and coronary artery obstruction was the outcome variable of the predictor model. Among the variables related to coronary disease, the predictor variables were the history of coronary artery disease (p < 0.001) and myocardium segmental deficit at the echocardiogram (p < 0.02). Conclusion: The antecedent of coronary disease and the myocardium segmental deficit at the echocardiogram were able to discriminate patients with acute pulmonary edema associated with obstructive coronary disease. Troponin values classified by two cardiologists as secondary to an acute non-ST-segment elevation myocardial infarction, and chest pain preceding the clinical picture were not able to discriminate patients with or without coronary obstruction and thus, the diagnosis of obstructive coronary disease should not be pursued based on the troponin value and/or chest pain preceding the clinical picture.</p></div