479 research outputs found
Balanced electric-magnetic dihole in Kaluza-Klein theory
We present a four-dimensional double-black-hole (or dihole) solution in
Kaluza-Klein theory, describing a superposition of an electrically charged and
a magnetically charged black hole. This system can be balanced for
appropriately chosen parameters, and the resulting space-time is completely
regular on and outside the event horizons. This solution was constructed using
the inverse-scattering method in five-dimensional vacuum gravity, in which it
describes a rotating black ring surrounding a static black hole on a Taub-NUT
background space. Various properties of this solution are studied, from both a
four- and five-dimensional perspective.Comment: 33 pages, 6 figures; v2: expanded discussion of phase space,
published versio
String Theory on Warped AdS_3 and Virasoro Resonances
We investigate aspects of holographic duals to time-like warped AdS_3
space-times--which include G\"odel's universe--in string theory. Using
worldsheet techniques similar to those that have been applied to AdS_3
backgrounds, we are able to identify space-time symmetry algebras that act on
the dual boundary theory. In particular, we always find at least one Virasoro
algebra with computable central charge. Interestingly, there exists a dense set
of points in the moduli space of these models in which there is actually a
second commuting Virasoro algebra, typically with different central charge than
the first. We analyze the supersymmetry of the backgrounds, finding related
enhancements, and comment on possible interpretations of these results. We also
perform an asymptotic symmetry analysis at the level of supergravity, providing
additional support for the worldsheet analysis.Comment: 24 pages + appendice
Mass hierarchy, mass gap and corrections to Newton's law on thick branes with Poincare symmetry
We consider a scalar thick brane configuration arising in a 5D theory of
gravity coupled to a self-interacting scalar field in a Riemannian manifold. We
start from known classical solutions of the corresponding field equations and
elaborate on the physics of the transverse traceless modes of linear
fluctuations of the classical background, which obey a Schroedinger-like
equation. We further consider two special cases in which this equation can be
solved analytically for any massive mode with m^2>0, in contrast with numerical
approaches, allowing us to study in closed form the massive spectrum of
Kaluza-Klein (KK) excitations and to compute the corrections to Newton's law in
the thin brane limit. In the first case we consider a solution with a mass gap
in the spectrum of KK fluctuations with two bound states - the massless 4D
graviton free of tachyonic instabilities and a massive KK excitation - as well
as a tower of continuous massive KK modes which obey a Legendre equation. The
mass gap is defined by the inverse of the brane thickness, allowing us to get
rid of the potentially dangerous multiplicity of arbitrarily light KK modes. It
is shown that due to this lucky circumstance, the solution of the mass
hierarchy problem is much simpler and transparent than in the (thin)
Randall-Sundrum (RS) two-brane configuration. In the second case we present a
smooth version of the RS model with a single massless bound state, which
accounts for the 4D graviton, and a sector of continuous fluctuation modes with
no mass gap, which obey a confluent Heun equation in the Ince limit. (The
latter seems to have physical applications for the first time within braneworld
models). For this solution the mass hierarchy problem is solved as in the
Lykken-Randall model and the model is completely free of naked singularities.Comment: 25 pages in latex, no figures, content changed, corrections to
Newton's law included for smooth version of RS model and an author adde
Unsuspected pulmonary alveolar proteinosis in a patient with acquired immunodeficiency syndrome: a case report
<p>Abstract</p> <p>Introduction</p> <p>Diffuse lung infiltrates are a common finding in patients with acquired immunodeficiency syndrome and causes range from infectious processes to malignancies or interstitial lung diseases. Pulmonary alveolar proteinosis is a rare pulmonary disorder rarely reported in patients infected with human immunodeficiency virus. Secondary pulmonary alveolar proteinosis is associated with conditions involving functional impairment or reduced numbers of alveolar macrophages. It can be caused by hematologic malignancies, inhalation of toxic dust, fumes or gases, infectious or pharmacologic immunosuppression, or lysinuric protein intolerance.</p> <p>Case presentation</p> <p>A 42-year-old African American man infected with human immunodeficiency virus was admitted with chronic respiratory symptoms and diffuse pulmonary infiltrates. Chest computed tomography revealed bilateral spontaneous pneumothoraces, for which he required bilateral chest tubes. Initial laboratory investigations did not reveal any contributory conditions. Histological examination of a lung biopsy taken during video-assisted thoracoscopy showed pulmonary alveolar proteinosis concurrent with cytomegalovirus pneumonitis. After ganciclovir treatment, our patient showed radiologic and clinical improvement.</p> <p>Conclusion</p> <p>The differential diagnosis for patients with immunosuppression and lung infiltrates requires extensive investigations. As pulmonary alveolar proteinosis is rare, the diagnosis can be easily missed. Our case highlights the importance of invasive investigations and histology in the management of patients infected with human immunodeficiency virus and pulmonary disease who do not respond to empiric therapy.</p
Supergravity Solutions from Floating Branes
We solve the equations of motion of five-dimensional ungauged supergravity
coupled to three U(1) gauge fields using a floating-brane Ansatz in which the
electric potentials are directly related to the gravitational warp factors. We
find a new class of non-BPS solutions, that can be obtained linearly starting
from an Euclidean four-dimensional Einstein-Maxwell base. This class - the
largest known so far - reduces to the BPS and almost-BPS solutions in certain
limits. We solve the equations explicitly when the base space is given by the
Israel-Wilson metric, and obtain solutions describing non-BPS D6 and anti-D6
branes kept in equilibrium by flux. We also examine the action of spectral flow
on solutions with an Israel-Wilson base and show that it relates these
solutions to almost-BPS solutions with a Gibbons-Hawking base.Comment: 24 pages, 1 figur
Voluntary exercise can strengthen the circadian system in aged mice
Consistent daily rhythms are important to healthy aging according to studies linking disrupted circadian rhythms with negative health impacts. We studied the effects of age and exercise on baseline circadian rhythms and on the circadian system's ability to respond to the perturbation induced by an 8 h advance of the light:dark (LD) cycle as a test of the system's robustness. Mice (male, mPer2luc/C57BL/6) were studied at one of two ages: 3.5 months (n = 39) and >18 months (n = 72). We examined activity records of these mice under entrained and shifted conditions as well as mPER2::LUC measures ex vivo to assess circadian function in the suprachiasmatic nuclei (SCN) and important target organs. Age was associated with reduced running wheel use, fragmentation of activity, and slowed resetting in both behavioral and molecular measures. Furthermore, we observed that for aged mice, the presence of a running wheel altered the amplitude of the spontaneous firing rate rhythm in the SCN in vitro. Following a shift of the LD cycle, both young and aged mice showed a change in rhythmicity properties of the mPER2::LUC oscillation of the SCN in vitro, and aged mice exhibited longer lasting internal desynchrony. Access to a running wheel alleviated some age-related changes in the circadian system. In an additional experiment, we replicated the effect of the running wheel, comparing behavioral and in vitro results from aged mice housed with or without a running wheel (>21 months, n = 8 per group, all examined 4 days after the shift). The impact of voluntary exercise on circadian rhythm properties in an aged animal is a novel finding and has implications for the health of older people living with environmentally induced circadian disruption
MRI of the kidney—state of the art
Ultrasound and computed tomography (CT) are modalities of first choice in renal imaging. Until now, magnetic resonance imaging (MRI) has mainly been used as a problem-solving technique. MRI has the advantage of superior soft-tissue contrast, which provides a powerful tool in the detection and characterization of renal lesions. The MRI features of common and less common renal lesions are discussed as well as the evaluation of the spread of malignant lesions and preoperative assessment. MR urography technique and applications are discussed as well as the role of MRI in the evaluation of potential kidney donors. Furthermore the advances in functional MRI of the kidney are highlighted
Differences between patients' and clinicians' report of sleep disturbance: a field study in mental health care in Norway
<p>Abstract</p> <p>Background</p> <p>The aims of the study was to assess the prevalence of diagnosed insomnia and the agreement between patient- and clinician-reported sleep disturbance and use of prescribed hypnotic medication in patients in treatment for mental disorders.</p> <p>Methods</p> <p>We used three cross-sectional, multicenter data-sets from 2002, 2005, and 2008. Data-set 1 included diagnostic codes from 93% of all patients receiving treatment in mental health care in Norway (<it>N </it>= 40261). Data-sets 2 (<it>N </it>= 1065) and 3 (<it>N </it>= 1181) included diagnostic codes, patient- and clinician-reported sleep disturbance, and use of prescribed hypnotic medication from patients in 8 mental health care centers covering 10% of the Norwegian population.</p> <p>Results</p> <p>34 patients in data-set 1 and none in data-sets 2 and 3 had a diagnosis of insomnia as a primary or comorbid diagnosis. In data-sets 2 and 3, 42% and 40% of the patients reported sleep disturbance, whereas 24% and 13% had clinician-reported sleep disturbance, and 7% and 9% used hypnotics. Patients and clinicians agreed in 29% and 15% of the cases where the patient or the clinician or both had reported sleep disturbance. Positive predictive value (PPV) of clinicians' evaluations of patient sleep disturbance was 62% and 53%. When the patient reported sleep disturbance as one of their most prominent problems PPV was 36% and 37%. Of the patients who received hypnotic medication, 23% and 29% had neither patient nor clinician-rated sleep disturbance.</p> <p>Conclusion</p> <p>When patients meet the criteria for a mental disorder, insomnia is almost never diagnosed, and sleep disturbance is imprecisely recognized relative to the patients' experience of sleep disturbance.</p
Search for gamma-ray emission from magnetars with the Fermi Large Area Telescope
We report on the search for 0.1-10 GeV emission from magnetars in 17 months
of Fermi Large Area Telescope (LAT) observations. No significant evidence for
gamma-ray emission from any of the currently-known magnetars is found. The most
stringent upper limits to date on their persistent emission in the Fermi-LAT
energy range are estimated between ~10^{-12}-10^{-10} erg/s/cm2, depending on
the source. We also searched for gamma-ray pulsations and possible outbursts,
also with no significant detection. The upper limits derived support the
presence of a cut-off at an energy below a few MeV in the persistent emission
of magnetars. They also show the likely need for a revision of current models
of outer gap emission from strongly magnetized pulsars, which, in some
realizations, predict detectable GeV emission from magnetars at flux levels
exceeding the upper limits identified here using the Fermi-LAT observations.Comment: ApJ Letters in press; Corresponding authors: Caliandro G. A., Hadasch
D., Rea N., Burnett
Stationary Black Holes: Uniqueness and Beyond
The spectrum of known black-hole solutions to the stationary Einstein
equations has been steadily increasing, sometimes in unexpected ways. In
particular, it has turned out that not all black-hole-equilibrium
configurations are characterized by their mass, angular momentum and global
charges. Moreover, the high degree of symmetry displayed by vacuum and
electro-vacuum black-hole spacetimes ceases to exist in self-gravitating
non-linear field theories. This text aims to review some developments in the
subject and to discuss them in light of the uniqueness theorem for the
Einstein-Maxwell system.Comment: Major update of the original version by Markus Heusler from 1998.
Piotr T. Chru\'sciel and Jo\~ao Lopes Costa succeeded to this review's
authorship. Significantly restructured and updated all sections; changes are
too numerous to be usefully described here. The number of references
increased from 186 to 32
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