758 research outputs found

    Bilateral Hipoglossal Nerve Palsy In Necrotizing Otitis Externa

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    [No abstract available]734576Benecke Jr., J.A., Management of osteomyelitis of the skull base (1989) Laryngoscope, 99 (12), pp. 1220-1223Boringa, J.B., Hoekstra, O.S., Roos, J.W., Bertelsmann, F.W., Multiple cranial nerve palsy after otitis externa: A case report (1995) Clin Neurol Neurosurg, 97, pp. 332-335Rubin, J., Yu, V.L., Malignant external otitis: Insights into pathogenesis, clinical manifestations and therapy (1998) Am J Med, 85, pp. 391-39

    Concurrent and predictive validity of glim criteria to identify undernutrition in hospitalized patients

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    Ewing's Sarcoma Of The Head And Neck.

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    CONTEXT: Ewing's sarcoma is a rare neoplasm, which usually arises in long bones of the limbs and in flat bones of the pelvis, with the involvement of head and neck bones being very unusual. CASE REPORT: a case of Ewing's sarcoma occurring in the mandible of a 35-year-old female. Pain and swelling of the tumor were the main complaints. The early hypothesis was an undifferentiated malignant neoplasm, possibly a sarcoma. The CT scan depicted an expansive lesion, encapsulated, with septa and characteristics of soft tissue, involving the left side of the mandible and extending to the surrounding tissues. The patient underwent surgical excision of the lesion, the definitive diagnosis of Ewing's sarcoma was established, and the patient commenced on radiotherapy.118619820

    Determinants of workplace exposure and release of ultrafine particles during atmospheric plasma spraying in the ceramic industry

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    Atmospheric plasma spraying (APS) is a frequently used technique to produce enhanced-property coatings for different materials in the ceramic industry. This work aimed to characterise and quantify the impact of APS on workplace exposure to airborne particles, with a focus on ultrafine particles (UFPs, <100 nm) and nanoparticles (<50 nm). Particle number, mass concentrations, alveolar lung deposited surface area concentration, and size distributions, in the range 10 nm – 20 μm were simultaneously monitored at the emission source, in the worker breathing zone, and in outdoor air. Different input materials (known as feedstock) were tested: (a) micro-sized powders, and (b) suspensions containing submicron- or nano-sized particles. Results evidenced significant UFP emissions (up to 3.3x106/cm3) inside the projection chamber, which impacted exposure in the breathing zone outside the projection chamber (up to 8.3x105/cm3). Environmental release of UFPs was also detected and quantified (3.9x105/cm330 ). Engineered nanoparticle (ENP) release to workplace air was also evidenced by TEM microscopy. UFP emissions were detected during the application of both micro-sized powder and suspensions containing submicron- or nano-sized particles, thus suggesting that emissions were process- (and not material-) dependent. An effective risk prevention protocol was implemented, which resulted in a reduction of worker UFP exposure in the breathing zone. These findings evidence the potential risk of occupational exposure to UFPs during atmospheric plasma spraying, and raise the need for further research on UFP formation mechanisms in high-energy industrial processes

    Ultrafine and nanoparticle formation and emission mechanisms during laser processing of ceramic materials

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    The use of laser technology in the ceramic industry is undergoing an increasing trend, as it improves surface properties. The present work aimed to assess ultrafine and nanoparticle emissions from two different types of laser treatments (tile sintering and ablation) applied to two types of tiles. New particle formation mechanisms were identified, as well as primary nanoparticle emissions, with concentrations reaching up to 6.7 x 10(6) particles Cm-3 and a mean diameter of 18 nm. Nanoparticle emission patterns were strongly dependent on temperature and raw tile chemical composition. Nucleation events were detected during the thermal treatment independently of the laser application. TOM images evidenced spherical ultrafine particles, originating from the tile melting processes. When transported across the indoor environment, particles increased in size (up to 38 nm) with concentrations remaining high (2.3 x 10(6) particles cm(-3)), Concentrations of metals such as Zn, Pb, Cu, Cr, As and al were found in particles < 250 nm

    Health risk assessment from exposure to particles during packing in working environments

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    Packing of raw materials in work environments is a known source of potential health impacts (respiratory, cardiovascular) due to exposure to airborne particles. This activity was selected to test different exposure and risk assessment tools, aiming to understand the effectiveness of source enclosure as a strategy to mitigate particle release. Worker exposure to particle mass and number concentrations was monitored during packing of 7 ceramic materials in 3 packing lines in different settings, with low (L), medium (M) and high (H) degrees of source enclosure. Results showed that packing lines L and M significantly increased exposure concentrations (119-609 μg m-3 respirable, 1150-4705 μg m-3 inhalable, 24755-51645 cm-3 particle number), while nonsignificant increases were detected in line H. These results evidence the effectiveness of source enclosure as a mitigation strategy, in the case of packing of ceramic materials. Total deposited particle surface area during packing ranged between 5.4-11.8x105 μm2 min-1, with particles depositing mainly in the alveoli (51-64%) followed by head airways (27-41%) and trachea bronchi (7-10%). The comparison between the results from different risk assessment tools (Stoffenmanager, ART, NanoSafer) and the actual measured exposure concentrations evidenced that all of the tools overestimated exposure concentrations, by factors of 1.5-8. Further research is necessary to bridge the current gap between measured and modelled health risk assessments

    Genomic screening of allelic and genotypic transmission ratio distortion in horse

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    The phenomenon in which the expected Mendelian inheritance is altered is known as transmission ratio distortion (TRD). The TRD analysis relies on the study of the transmission of one of the two alleles from a heterozygous parent to the offspring. These distortions are due to biological mechanisms affecting gametogenesis, embryo development and/or postnatal viability, among others. In this study, TRD phenomenon was characterized in horses using SNP-by-SNP model by TRDscan v.2.0 software. A total of 1,041 Pura Raza Español breed horses were genotyped with 554,634 SNPs. Among them, 277 horses genotyped in trios (stallion-mare-offspring) were used to perform the TRD analysis. Our results revealed 140 and 42 SNPs with allelic and genotypic patterns, respectively. Among them, 63 displayed stallion-TRD and 41 exhibited mare-TRD, while 36 SNPs showed overall TRD. In addition, 42 SNPs exhibited heterosis pattern. Functional analyses revealed that the annotated genes located within the TRD regions identified were associated with biological processes and molecular functions related to spermatogenesis, oocyte division, embryonic development, and hormonal activity. A total of 10 functional candidate genes related to fertility were found. To our knowledge, this is the most extensive study performed to evaluate the presence of alleles and functional candidate genes with transmission ratio distortion affecting reproductive performance in the domestic horse.Fil: Laseca, Nora. Universidad de Córdoba; EspañaFil: Cánovas, Ángela. University of Guelph; CanadáFil: Valera, Mercedes. Universidad de Sevilla; EspañaFil: Id Lahoucine, Samir. Scotland’s Rural College; Reino UnidoFil: Perdomo González, Davinia Isabel. Universidad de Sevilla; EspañaFil: Fonseca, Pablo A. S.. Universidad de León; EspañaFil: Demyda-peyrás, Sebastian. Universidad de Córdoba; España. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Molina, Antonio. Universidad de Córdoba; Españ
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