The VANDELS ESO public spectroscopic survey

VANDELS is a uniquely deep spectroscopic survey of high-redshift galaxies with the VIMOS spectrograph on ESO’s Very Large Telescope (VLT). The survey has obtained ultradeep optical (0.48 < λ < 1.0 μ m) spectroscopy of ≃2100 galaxies within the redshift interval 1.0 ≤ z ≤ 7.0, over a total area of ≃0.2 deg2 centred on the CANDELS Ultra Deep Survey and Chandra Deep Field South fields. Based on accurate photometric redshift pre-selection, 85 per cent of the galaxies targeted by VANDELS were selected to be at z ≥ 3. Exploiting the red sensitivity of the refurbished VIMOS spectrograph, the fundamental aim of the survey is to provide the high-signal-to-noise ratio spectra necessary to measure key physical properties such as stellar population ages, masses, metallicities, and outflow velocities from detailed absorption-line studies. Using integration times calculated to produce an approximately constant signal-to-noise ratio (20 < tint< 80 h), the VANDELS survey targeted: (a) bright star-forming galaxies at 2.4 ≤ z ≤ 5.5, (b) massive quiescent galaxies at 1.0 ≤ z ≤ 2.5, (c) fainter star-forming galaxies at 3.0 ≤ z ≤ 7.0, and (d) X-ray/Spitzer-selected active galactic nuclei and Herschel-detected galaxies. By targeting two extragalactic survey fields with superb multiwavelength imaging data, VANDELS will produce a unique legacy data set for exploring the physics underpinning high-redshift galaxy evolution. In this paper, we provide an overview of the VANDELS survey designed to support the science exploitation of the first ESO public data release, focusing on the scientific motivation, survey design, and target selection

Axial solutions for multiple objective linear problems. An application to target setting in DEA models with preferences

In this paper we introduce the class of axial solutions for multiple objective optimization problems in contexts in which partial information on preference weights is available. These solutions combine the use of an improvement axis to direct the search of the most preferred result with the concept of efficiency with respect to preference information. In addition, we show how this solution is used in data envelopment analysis in order to set realistic targets in accordance with either the partially specified preferences of a single decision maker, or the different individual preference information provided by the members of a group of decision makers.Multiple objective linear problems Partial information DEA

Core, least core and nucleolus for multiple scenario cooperative games

Multiple scenario cooperative games model situations where the worth of the coalitions is valued in different scenarios simultaneously or under different states of nature. In this paper we analyze solution concepts for this class of games keeping the multidimensional nature of the characteristic function. We obtain extensions of the notions of core, least core and nucleolus, and explore the relationship among these solution concepts

Soluciones Maxmin en Juegos de Negociación n-Personales

En este trabajo proponemos utilizar el criterio maxmin para obtener soluciones equilibradas en juegos de negociación de n agentes. Se analizan las relaciones existentes entre las soluciones obtenidas al utilizar un criterio consistente en la maximización del mínimo de las utilidades obtenidas por los agentes en relación al punto de desacuerdo, y algunas soluciones axiomáticas clásicas, como son la solución de Kalai-Smorodinsky, la solución igualitaria y en general, la familia de soluciones proporcionales o α-igualitarias.En este trabajo proponemos utilizar el criterio maxmin para obtener soluciones equilibradas en juegos de negociación de n agentes. Se analizan las relaciones existentes entre las soluciones obtenidas al utilizar un criterio consistente en la maximización del mínimo de las utilidades obtenidas por los agentes en relación al punto de desacuerdo, y algunas soluciones axiomáticas clásicas, como son la solución de Kalai-Smorodinsky, la solución igualitaria y en general, la familia de soluciones proporcionales o α-igualitarias

Using MCDA methods THOR in an application for outranking the ballast water management options

The Multicriteria Analysis Methodology has been developed in order to support and guide decision-makers in the evaluation and selection of alternatives/solutions. In this case, it is used to compare alternatives for the management ballast water (BW) exchange systems and treatment methods.<br>O Apoio Multicritério à Decisão (AMD) desenvolve metodologias que ajudam o tomador ou agente de decisão a avaliar e selecionar alternativas. Este trabalho apresenta uma aplicação real do AMD em uma situação de ordenação de alternativas para o gerenciamento do problema de água de lastro

In silico validation of RNA-Seq results can identify gene fusions with oncogenic potential in glioblastoma

Altres ajuts: Fundació La Marató de TV3 (665/C/2013)RNA-Sequencing (RNA-Seq) can identify gene fusions in tumors, but not all these fusions have functional consequences. Using multiple data bases, we have performed an in silico analysis of fusions detected by RNA-Seq in tumor samples from 139 newly diagnosed glioblastoma patients to identify in-frame fusions with predictable oncogenic potential. Among 61 samples with fusions, there were 103 different fusions, involving 167 different genes, including 20 known oncogenes or tumor suppressor genes (TSGs), 16 associated with cancer but not oncogenes or TSGs, and 32 not associated with cancer but previously shown to be involved in fusions in gliomas. After selecting in-frame fusions able to produce a protein product and running Oncofuse, we identified 30 fusions with predictable oncogenic potential and classified them into four non-overlapping categories: six previously described in cancer; six involving an oncogene or TSG; four predicted by Oncofuse to have oncogenic potential; and 14 other in-frame fusions. Only 24 patients harbored one or more of these 30 fusions, and only two fusions were present in more than one patient: FGFR3::TACC3 and EGFR::SEPTIN14. This in silico study provides a good starting point for the identification of gene fusions with functional consequences in the pathogenesis or treatment of glioblastom