1,052 research outputs found

    Extraction and Quantification of Atrazine

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    Accuracy of Medical-Surgical Nurse’s Prediction of Patient’s Health Literacy Level

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    Low health literacy (HL) is common in rural locations with limited resources and abundant socioeconomic issues. This study sought to determine if a relationship existed between a nurse’s assessment of medical-surgical patient’s HL levels and actual HL levels [measured by the Newest Vital Sign (NVS)] of patients seeking care in a rural border region. Data collected from 84 RNs and patients revealed a moderately strong positive correlation of rs=0.418(p=.01), between the RN’s prediction of patient’s HLlevel and actual HL level, contributing to the support for the use of standardized HL assessment tools to accurately identify low HL in patient populations. Recommended Citation Williams, S. A. (2020, October 1-2). Accuracy of medical-surgical nurse’s prediction of patient’s health literacy level [Poster presentation]. Walden University Research Conference 2020 (online). https://scholarworks.waldenu.edu/researchconference/2020/posters/21

    Dutch Euroscepticism: The Manifestation of Pre-Financial Crisis Fears in Post- Financial Crisis Politics and Voting Patterns

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    This paper seeks to explain the recent rise in Dutch Euroscepticism, especially in the wake of the Great Recession and the Euro Crisis. The rise of Eurosceptic sentiment reflects more than just a “left-” versus “right-wing” political divide in Dutch politics; rather, it signals an increasingly prevalent divide between pro-EU and anti-EU voters and policies. Though Eurosceptic sentiment already existed in Dutch politics at the beginning of the 21st century, this paper argues that the financial crises of the 2000s played a major role in the significant rise of Eurosceptic sentiment and rhetoric in Dutch politics. The Great Recession and the resulting Euro Crisis allowed the pre-existing and potentially more “dormant” Eurosceptic sentiments to break through and influence Dutch politics through populist Eurosceptic parties like the Dutch Freedom Party (PVV) and Dutch Socialist Party (SP), as evidenced in voting outcomes in the parliamentary elections following the era of financial crises

    You Got the Job, Now What?: An Evaluation of the New Employee Orientation Program at the University of Montana

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    When new members begin their employment with an organization, they make a transition from being an outsider to an insider. A significant moment arranged by the organization to facilitate socialization is the New Employee Orientation (NEO). This evaluation examines NEO in relation to the encounter stage of the socialization process. Focusing on what and how information is provided during the NEO program at the University of Montana (UM), this evaluation is based on research of the informational components of Klein and Weaver (2000) and the socialization tactics from Van Maanen and Schein (1979). General conclusions regarding NEO and socialization as well as recommendations for improvement are presented for the benefit of the Human Resource Services office at UM

    Unveiling the orbital angular momentum and acceleration of electron beams

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    New forms of electron beams have been intensively investigated recently, including vortex beams carrying orbital angular momentum, as well as Airy beams propagating along a parabolic trajectory. Their traits may be harnessed for applications in materials science, electron microscopy and interferometry, and so it is important to measure their properties with ease. Here we show how one may immediately quantify these beams' parameters without need for additional fabrication or non-standard microscopic tools. Our experimental results are backed by numerical simulations and analytic derivation.Comment: 2 figures in text, 2 in supplementar

    Radiation measurements in the new tandem accelerator FEL

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    The measurements of both spontaneous and stimulated emissions of radiation in the newly configured Israeli EA-FEL are made for the first time. The radiation at the W-band was measured and characterized. The results match the predictions of our earlier theoretical modeling and calculations.Comment: 4 pages, 3 figures, FEL 2003 Conference repor

    Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis

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    Necrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal morbidity and mortality in premature infants. Human and animal studies suggest a role for Paneth cells in NEC pathogenesis. Paneth cells play critical roles in host-microbial interactions and epithelial homeostasis. The ramifications of eliminating Paneth cell function on the immature host-microbial axis remains incomplete. Paneth cell function was depleted in the immature murine intestine using chemical and genetic models, which resulted in intestinal injury consistent with NEC. Paneth cell depletion was confirmed using histology, electron microscopy, flow cytometry, and real time RT-PCR. Cecal samples were analyzed at various time points to determine the effects of Paneth cell depletion with and without Klebsiella gavage on the microbiome. Deficient Paneth cell function induced significant compositional changes in the cecal microbiome with a significant increase in Enterobacteriacae species. Further, the bloom of Enterobacteriaceae species that occurs is phenotypically similar to what is seen in human NEC. This further strengthens our understanding of the importance of Paneth cells to intestinal homeostasis in the immature intestine

    Public welfare or sectarianism: A new challenge for planning

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    Introduction Theoretical background Methodology The Haredi in Jerusalem Kiryat-Ha'Yovel “Terrain of interests” between Haredi and secular in Kiryat-Ha'Yovel Organisation in housing Potential for influencing planning decisions Conclusions: failure of liberalism or all-you-can-grab planning? Full Article Figures & data References Citations Metrics Reprints & Permissions PDF Abstract This article examines the weaknesses of liberal planning institutions when dealing with organised group action. The case under review, the Kiryat-Ha'Yovel neighbourhood in Jerusalem, was considered as secular for many years. In 2000 the neighbourhood became attractive to the nearby Haredi (ultra-orthodox Jews) group of the “Kol-Torah’ community. Differences in lifestyle led to a collision between the group of “Kol-Torah”, who began “Haredification” processes to change the character of the area to be suitable to Haredim, and the veteran population, who tried to prevent it. Identifying the main engines of organised neighbourhood change and evaluating the difficulties of liberalism dealing with non-autonomous individuals in the housing market sheds light on similar processes occurring in other city centres with diverse population groups

    The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM

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    The activation of ATR-ATRIP in response to double-stranded DNA breaks (DSBs) depends upon ATM in human cells and Xenopus egg extracts. One important aspect of this dependency involves regulation of TopBP1 by ATM. In Xenopus egg extracts, ATM associates with TopBP1 and thereupon phosphorylates it on S1131. This phosphorylation enhances the capacity of TopBP1 to activate the ATR-ATRIP complex. We show that TopBP1 also interacts with the Mre11-Rad50-Nbs1 (MRN) complex in egg extracts in a checkpoint-regulated manner. This interaction involves the Nbs1 subunit of the complex. ATM can no longer interact with TopBP1 in Nbs1-depleted egg extracts, which suggests that the MRN complex helps to bridge ATM and TopBP1 together. The association between TopBP1 and Nbs1 involves the first pair of BRCT repeats in TopBP1. In addition, the two tandem BRCT repeats of Nbs1 are required for this binding. Functional studies with mutated forms of TopBP1 and Nbs1 suggested that the BRCT-dependent association of these proteins is critical for a normal checkpoint response to DSBs. These findings suggest that the MRN complex is a crucial mediator in the process whereby ATM promotes the TopBP1-dependent activation of ATR-ATRIP in response to DSBs

    Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling

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    Large brain size is one of the defining characteristics of modern humans. Seckel syndrome (MIM 210600), a disorder of markedly reduced brain and body size, is associated with defective ATR-dependent DNA damage signaling. Only a single hypomorphic mutation of ATR has been identified in this genetically heterogeneous condition. We now report that mutations in the gene encoding pericentrin (PCNT)--resulting in the loss of pericentrin from the centrosome, where it has key functions anchoring both structural and regulatory proteins--also cause Seckel syndrome. Furthermore, we find that cells of individuals with Seckel syndrome due to mutations in PCNT (PCNT-Seckel) have defects in ATR-dependent checkpoint signaling, providing the first evidence linking a structural centrosomal protein with DNA damage signaling. These findings also suggest that other known microcephaly genes implicated in either DNA repair responses or centrosomal function may act in common developmental pathways determining human brain and body size
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