1,092 research outputs found
The Isomorphism Relation Between Tree-Automatic Structures
An -tree-automatic structure is a relational structure whose domain
and relations are accepted by Muller or Rabin tree automata. We investigate in
this paper the isomorphism problem for -tree-automatic structures. We
prove first that the isomorphism relation for -tree-automatic boolean
algebras (respectively, partial orders, rings, commutative rings, non
commutative rings, non commutative groups, nilpotent groups of class n >1) is
not determined by the axiomatic system ZFC. Then we prove that the isomorphism
problem for -tree-automatic boolean algebras (respectively, partial
orders, rings, commutative rings, non commutative rings, non commutative
groups, nilpotent groups of class n >1) is neither a -set nor a
-set
Enhanced directed random walk for the identification of breast cancer prognostic markers from multiclass expression data
Artificial intelligence in healthcare can potentially identify the probability of contracting a particular disease more accurately. There are five common molecular subtypes of breast cancer: luminal A, luminal B, basal, ERBB2, and normalâlike. Previous investigations showed that pathway-based microarray analysis could help in the identification of prognostic markers from gene expres-sions. For example, directed random walk (DRW) can infer a greater reproducibility power of the pathway activity between two classes of samples with a higher classification accuracy. However, most of the existing methods (including DRW) ignored the characteristics of different cancer sub-types and considered all of the pathways to contribute equally to the analysis. Therefore, an enhanced DRW (eDRW+) is proposed to identify breast cancer prognostic markers from multiclass expression data. An improved weight strategy using oneâway ANOVA (Fâtest) and pathway selection based on the greatest reproducibility power is proposed in eDRW+. The experimental results show that the eDRW+ exceeds other methods in terms of AUC. Besides this, the eDRW+ identifies 294 gene markers and 45 pathway markers from the breast cancer datasets with better AUC. There-fore, the prognostic markers (pathway markers and gene markers) can identify drug targets and look for cancer subtypes with clinically distinct outcomes
Physical Activity Research in Nursing
Purpose: To present exemplars of physical activity research in nursing, illustrate the importance of physical activity research across the lifespan, and recommend directions for theory development and research.
Methods: Studies of physical activity and exercise currently being conducted by nurse investigators were reported and critiqued by attendees of the Midwest Nursing Research Society 2000 Preconference session entitled âPromoting Physical Activity Among Diverse Groups Across the Health Continuum.â Physical activity and exercise literature during the past decade was reviewed. Databases searched included Medline, CINAHL, Wilson, and ERIC.
Findings: Investigators have emphasized the need to evaluate the effects of theory-based physical activity interventions designed to alter key correlates of physical activity identified through descriptive research.
Conclusions: Regular physical activity is necessary for health promotion and disease prevention for all populations. Continued research in this important area of health behavior is critical to identify the most effective interventions to increase physical activity among diverse populations
Thermodynamic consistency in dissipative particle dynamics simulations of strongly nonideal liquids and liquid mixtures
Profil Kandungan Protein dan Tekstur Tahu Akibat Penambahan Fitat pada Proses Pembuatan Tahu
Telah dilakukan penelitian yang bertujuan untuk mempelajari profil kandungan protein dan tekstur tahu akibat penambahan fitat pada proses pembuatan tahu dengan koagulan asam asetat. Fitat merupakan senyawa monoinositol heksafosfat yang terdapat pada biji-bijian berkisar 1-5 % (b/b) dan dikenal sebagai antioksidan alami. Oleh karena itu diupayakan untuk memanfaatkan fitat kedalam proses pengolahan makanan untuk meningkatkan produknya.Pada penelitian ini tekstur tahu diukur dengan alat Penetrometer dan kadar protein dengan metode Kjeldahl pada variasi pH penggumpalan protein susu kedelai tanpa penambahan fitat dan dengan penambahan fitat.Hasil penelitian menunjukkan bahwa variasi pH penggumpalan protein susu kedelai yang ditambahi fitat ternyata mempengaruhi gumpalan tahu yang terbentuk. Jika dibandingkan dengan tahu tanpa penambahan fitat maka terjadi penurunan berat protein tahu pada pH titik isoelektrik (4,5) yaitu dari 8,131 g menjadi 6,273 g. Bertambahnya konsentrasi fitat hingga 0,05 % (b/v) menyebabkan naiknya kekerasan tahu dari 3,02 cm menjadi 1,88 cm. Diatas konsentrasi tersebut kekerasan tahu menurun. Dari hasil tersebut dapat disimpulkan bahwa penambahan fitat akan menyebabkan meningkatnya kekerasan tahu namun dapat menurunkan kadar protein tahu
A review on recent progress in machine learning and deep learning methods for cancer classification on gene expression data
Data-driven model with predictive ability are important to be used in medical and healthcare. However, the most challenging task in predictive modeling is to construct a prediction model, which can be addressed using machine learning (ML) methods. The methods are used to learn and trained the model using a gene expression dataset without being programmed explicitly. Due to the vast amount of gene expression data, this task becomes complex and time consuming. This paper provides a recent review on recent progress in ML and deep learning (DL) for cancer classification, which has received increasing attention in bioinformatics and computational biology. The development of cancer classification methods based on ML and DL is mostly focused on this review. Although many methods have been applied to the cancer classification problem, recent progress shows that most of the successful techniques are those based on supervised and DL methods. In addition, the sources of the healthcare dataset are also described. The development of many machine learning methods for insight analysis in cancer classification has brought a lot of improvement in healthcare. Currently, it seems that there is highly demanded further development of efficient classification methods to address the expansion of healthcare applications
Molecular and in situ characterization of cadmium-resistant diversified extremophilic strains of Pseudomonas for their bioremediation potential
OtotoksiÄne tvari na radnom mjestu: kratak uvid u stanje
Ototoxic chemicals can impair the sense of hearing and balance. Lately, efforts have been intensifi ed to compile evidence-based lists of workplace agents with ototoxic properties. This article gives a rough overview of the latest relevant publications, which confirm that toluene, styrene, and lead should receive particular attention as ototoxic substances at the workplace. Moreover, there is sufficient evidence that occupational exposure to trichloroethylene, mercury, carbon monoxide, and carbon disulfide can affect the ear. Based on the existing information, industrial hygienists should make sure that occupational health professionals and the workforce are made aware of the risks posed by ototoxic substances; support their replacement or new technical measures to reduce exposure; make these substances a part of regular screening, develop tools that can early diagnose chemically induced hearing impairment, and investigate further into the ototoxic properties of these substances. Further research should focus on quantifying the combined effects of ototoxic substances and noise.OtotoksiÄne kemikalije mogu naruĆĄiti osjetilo sluha i ravnoteĆŸu. Nedavno su uloĆŸeni dodatni napori u izradu znanstveno utemeljenih popisa tvari koje su prisutne na radnom mjestu, a koje imaju ototoksiÄna svojstva. Ovaj rad daje kratak uvid u najnovije publikacije objavljene na ovu temu. Usporedba navedenih publikacija potvrÄuje da bi toluen, stiren i olovo trebalo razmatrati kao izrazito bitne ototoksiÄne tvari koje postoje na radnom mjestu. Nadalje, postoje dovoljni dokazi koji potvrÄuju da ototoksiÄne tvari poput trikloretilena, ĆŸive, ugljikova monoksida i disulfida u radnom okruĆŸenju mogu oĆĄtetiti sluh. Temeljem postojeÄih informacija struÄnjaci u podruÄju higijene rada trebali bi upozoravati struÄnjake u podruÄju medicine rada i same radnike na rizike koje ototoksiÄne tvari predstavljaju; poticati ih na zamjenu takvih tvari ili uvoÄenje novih mjera za smanjenje izlaganja; ukljuÄiti ototoksiÄne tvari u redoviti program praÄenja i osmisliti mjere za rano otkrivanje oĆĄteÄenja sluha zbog izloĆŸenosti kemijskim tvarima; dodatno istraĆŸiti ototoksiÄna svojstva ovih tvari. BuduÄa istraĆŸivanja trebala bi se usredotoÄiti na izraÄun ukupnih uÄinaka ototoksiÄnih tvari i buke
Search for CP violation in decays
A model-independent search for direct CP violation in the Cabibbo suppressed
decay in a sample of approximately 370,000 decays is
carried out. The data were collected by the LHCb experiment in 2010 and
correspond to an integrated luminosity of 35 pb. The normalized Dalitz
plot distributions for and are compared using four different
binning schemes that are sensitive to different manifestations of CP violation.
No evidence for CP asymmetry is found.Comment: 13 pages, 8 figures, submitted to Phys. Rev.
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