Nonlinear self-flipping of polarization states in asymmetric waveguides

Waveguides of subwavelength dimensions with asymmetric geometries, such as rib waveguides, can display nonlinear polarization effects in which the nonlinear phase difference dominates the linear contribution, provided the birefringence is sufficiently small. We demonstrate that self-flipping polarization states can appear in such rib waveguides at low (mW) power levels. We describe an optical power limiting device with optimized rib waveguide parameters that can operate at low powers with switching properties

FORTRAN programs for calculating lower ionosphere electron densities and collision frequencies from rocket data

FORTRAN programs for calculating lower ionosphere electron densities and collision frequencie

Self-written waveguides in photopolymerizable resins

We study the optically-induced growth and interaction of self-written waveguides in a photopolymerizable resin. We investigate experimentally how the interaction depends on the mutual coherence and relative power of the input beams, and suggest an improved analytical model that describes the growth of single self-written waveguides and the main features of their interaction in photosensitive materials.Comment: 3 pages, 3 figure

Nanoliter-scale, regenerable ion sensor: Sensing with surface functionalized microstructured optical fiber

Femtosecond laser written Bragg gratings have been written in exposed-core microstructured optical fibers with core diameters ranging from 2.7 μm to 12.5 μm and can be spliced to conventional single mode fiber. Writing a Bragg grating on an open core fiber allows for real-time refractive index based sensing, with a view to multiplexed biosensing. Smaller core fibers are shown both experimentally and theoretically to provide a higher sensitivity. A 7.5 μm core diameter fiber is shown to provide a good compromise between sensitivity and practicality and was used for monitoring the deposition of polyelectrolyte layers, an important first step in developing a biosensor.Sabrina Heng, Mai-Chi Nguyen, Roman Kostecki, Tanya M. Monro and Andrew D. Abellhttp://spie.org/app/program/index.cfm?fuseaction=conferencedetail&conference_id=1081415&event_id=102223

Biochemical evolution in response to intensive harvesting in algae: evolution of quality and quantity

Evolutionary responses to indirect selection pressures imposed by intensive harvesting are increasingly common. While artificial selection has shown that biochemical components can show rapid and dramatic evolution, it remains unclear as to whether intensive harvesting can inadvertently induce changes in the biochemistry of harvested populations. For applications such as algal culture, many of the desirable bioproducts could evolve in response to harvesting, reducing cost-effectiveness, but experimental tests are lacking. We used an experimental evolution approach where we imposed heavy and light harvesting regimes on multiple lines of an alga of commercial interest for twelve cycles of harvesting and then placed all lines in a common garden regime for four cycles. We have previously shown that lines in a heavy harvesting regime evolve a live fast phenotype with higher growth rates relative to light harvesting regimes. Here, we show that algal biochemistry also shows evolutionary responses, although they were temporarily masked by differences in density under the different harvesting regimes. Heavy harvesting regimes, relative to light harvesting regimes, had reduced productivity of desirable bioproducts, particularly fatty acids. We suggest that commercial operators wishing to maximize productivity of desirable bioproducts should maintain mother cultures, kept at higher densities (which tend to select for desirable phenotypes), and periodically restart their intensively harvested cultures to minimize the negative consequences of biochemical evolution. Our study shows that the burgeoning algal culture industry should pay careful attention to the role of evolution in intensively harvested crops as these effects are nontrivial if subtle

Dynamic self-referencing approach to whispering gallery mode biosensing and its application to measurement within undiluted serum

Biosensing within complex biological samples requires a sensor that can compensate for fluctuations in the signal due to changing environmental conditions and nonspecific binding events. To achieve this, we developed a novel self-referenced biosensor consisting of two almost identically sized dye-doped polystyrene microspheres placed on adjacent holes at the tip of a microstructured optical fiber (MOF). Here self-referenced biosensing is demonstrated with the detection of Neutravidin in undiluted, immunoglobulin-deprived human serum samples. The MOF allows remote excitation and collection of the whispering gallery modes (WGMs) of the microspheres while also providing a robust and easy to manipulate dip-sensing platform. By taking advantage of surface functionalization techniques, one microsphere acts as a dynamic reference, compensating for nonspecific binding events and changes in the environment (such as refractive index and temperature), while the other microsphere is functionalized to detect a specific interaction. The almost identical size allows the two spheres to have virtually identical refractive index sensitivity and surface area, while still having discernible WGM spectra. This ensures their responses to nonspecific binding and environmental changes are almost identical, whereby any specific changes, such as binding events, can be monitored via the relative movement between the two sets of WGM peaks.Tess Reynolds, Alexandre Franc, ois, Nicolas Riesen, Michelle E. Turvey, Stephen J. Nicholls, Peter Hoffmann, and Tanya M. Monr

A fiber-tip label-free biological sensing platform: A practical approach toward in-vivo sensing

The platform presented here was devised to address the unmet need for real time label-free in vivo sensing by bringing together a refractive index transduction mechanism based on Whispering Gallery Modes (WGM) in dye doped microspheres and Microstructured Optical Fibers. In addition to providing remote excitation and collection of the WGM signal, the fiber provides significant practical advantages such as an easy manipulation of the microresonator and the use of this sensor in a dip sensing architecture, alleviating the need for a complex microfluidic interface. Here, we present the first demonstration of the use of this approach for biological sensing and evaluate its limitation in a sensing configuration deprived of liquid flow which is most likely to occur in an in vivo setting. We also demonstrate the ability of this sensing platform to be operated above its lasing threshold, enabling enhanced device performance.Alexandre François, Tess Reynolds, and Tanya M. Monr